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Showing 253 to 262 of 262 entries
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Drivers of Burnout Among Critical Care Providers: A Multi-Center Mixed Methods Study.

Chest

Mehta AB, Lockhart S, Reed K, Griesmer C, Glasgow RE, Moss M, Douglas IS, Morris MA.
PMID: 34896094
Chest. 2021 Dec 08; doi: 10.1016/j.chest.2021.11.034. Epub 2021 Dec 08.

BACKGROUND: Critical care practitioners have some of the highest levels of burnout in healthcare.RESEARCH QUESTION: What are key drivers of burnout across the multidisciplinary ICU team?STUDY DESIGN AND METHODS: We conducted a multi-center mixed methods cohort study in ICUs...

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Mehta AB, Lockhart S, Reed K, et al. Drivers of Burnout Among Critical Care Providers: A Multi-Center Mixed Methods Study. Chest. 2021;doi: 10.1016/j.chest.2021.11.034.
Mehta, A. B., Lockhart, S., Reed, K., Griesmer, C., Glasgow, R. E., Moss, M., Douglas, I. S., & Morris, M. A. (2021). Drivers of Burnout Among Critical Care Providers: A Multi-Center Mixed Methods Study. Chest, . https://doi.org/10.1016/j.chest.2021.11.034
Mehta, Anuj B, et al. "Drivers of Burnout Among Critical Care Providers: A Multi-Center Mixed Methods Study." Chest vol. (2021). doi: https://doi.org/10.1016/j.chest.2021.11.034
Mehta AB, Lockhart S, Reed K, Griesmer C, Glasgow RE, Moss M, Douglas IS, Morris MA. Drivers of Burnout Among Critical Care Providers: A Multi-Center Mixed Methods Study. Chest. 2021 Dec 08; doi: 10.1016/j.chest.2021.11.034. Epub 2021 Dec 08. PMID: 34896094.
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Identification of Parachlamydiaceae DNA in nasal and rectal passages of healthy dairy cattle.

Journal of applied microbiology

Wheelhouse N, Hearn J, Livingstone M, Flockhart A, Dagleish M, Longbottom D.
PMID: 34932865
J Appl Microbiol. 2021 Dec 21; doi: 10.1111/jam.15422. Epub 2021 Dec 21.

AIMS: The order Chlamydiales comprises a broad range of bacterial pathogens and endosymbionts, which infect a wide variety of host species. Within this order, members of the family Parachlamydiaceae, which includes Parachlamydia and Neochlamydia species, have been particularly associated...

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Wheelhouse N, Hearn J, Livingstone M, et al. Identification of Parachlamydiaceae DNA in nasal and rectal passages of healthy dairy cattle. J Appl Microbiol. 2021;doi: 10.1111/jam.15422.
Wheelhouse, N., Hearn, J., Livingstone, M., Flockhart, A., Dagleish, M., & Longbottom, D. (2021). Identification of Parachlamydiaceae DNA in nasal and rectal passages of healthy dairy cattle. Journal of applied microbiology, . https://doi.org/10.1111/jam.15422
Wheelhouse, Nick, et al. "Identification of Parachlamydiaceae DNA in nasal and rectal passages of healthy dairy cattle." Journal of applied microbiology vol. (2021). doi: https://doi.org/10.1111/jam.15422
Wheelhouse N, Hearn J, Livingstone M, Flockhart A, Dagleish M, Longbottom D. Identification of Parachlamydiaceae DNA in nasal and rectal passages of healthy dairy cattle. J Appl Microbiol. 2021 Dec 21; doi: 10.1111/jam.15422. Epub 2021 Dec 21. PMID: 34932865.
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Mastering Atari, Go, chess and shogi by planning with a learned model.

Nature

Schrittwieser J, Antonoglou I, Hubert T, Simonyan K, Sifre L, Schmitt S, Guez A, Lockhart E, Hassabis D, Graepel T, Lillicrap T, Silver D.
PMID: 33361790
Nature. 2020 Dec;588(7839):604-609. doi: 10.1038/s41586-020-03051-4. Epub 2020 Dec 23.

Constructing agents with planning capabilities has long been one of the main challenges in the pursuit of artificial intelligence. Tree-based planning methods have enjoyed huge success in challenging domains, such as chess

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Schrittwieser J, Antonoglou I, Hubert T, et al. Mastering Atari, Go, chess and shogi by planning with a learned model. Nature. 2020;588(7839):604-609doi: 10.1038/s41586-020-03051-4.
Schrittwieser, J., Antonoglou, I., Hubert, T., Simonyan, K., Sifre, L., Schmitt, S., Guez, A., Lockhart, E., Hassabis, D., Graepel, T., Lillicrap, T., & Silver, D. (2020). Mastering Atari, Go, chess and shogi by planning with a learned model. Nature, 588(7839), 604-609. https://doi.org/10.1038/s41586-020-03051-4
Schrittwieser, Julian, et al. "Mastering Atari, Go, chess and shogi by planning with a learned model." Nature vol. 588,7839 (2020): 604-609. doi: https://doi.org/10.1038/s41586-020-03051-4
Schrittwieser J, Antonoglou I, Hubert T, Simonyan K, Sifre L, Schmitt S, Guez A, Lockhart E, Hassabis D, Graepel T, Lillicrap T, Silver D. Mastering Atari, Go, chess and shogi by planning with a learned model. Nature. 2020 Dec;588(7839):604-609. doi: 10.1038/s41586-020-03051-4. Epub 2020 Dec 23. PMID: 33361790.
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World Workshop on Oral Medicine VII: Bleeding control interventions for invasive dental procedures in patients with inherited functional platelet disorders: A systematic review.

Oral surgery, oral medicine, oral pathology and oral radiology

Karasneh J, Christoforou J, Walker JS, Dios PD, Lockhart PB, Patton LL.
PMID: 34758941
Oral Surg Oral Med Oral Pathol Oral Radiol. 2021 Aug 14; doi: 10.1016/j.oooo.2021.08.003. Epub 2021 Aug 14.

OBJECTIVES: The objective of this study was to determine bleeding control interventions (BCIs) that were reported to be effective in controlling postoperative bleeding in patients with inherited functional platelet disorders (IFPDs) undergoing invasive dental procedures.STUDY DESIGN: We searched MEDLINE/PubMed,...

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Karasneh J, Christoforou J, Walker JS, et al. World Workshop on Oral Medicine VII: Bleeding control interventions for invasive dental procedures in patients with inherited functional platelet disorders: A systematic review. Oral Surg Oral Med Oral Pathol Oral Radiol. 2021;doi: 10.1016/j.oooo.2021.08.003.
Karasneh, J., Christoforou, J., Walker, J. S., Dios, P. D., Lockhart, P. B., & Patton, L. L. (2021). World Workshop on Oral Medicine VII: Bleeding control interventions for invasive dental procedures in patients with inherited functional platelet disorders: A systematic review. Oral surgery, oral medicine, oral pathology and oral radiology, . https://doi.org/10.1016/j.oooo.2021.08.003
Karasneh, Jumana, et al. "World Workshop on Oral Medicine VII: Bleeding control interventions for invasive dental procedures in patients with inherited functional platelet disorders: A systematic review." Oral surgery, oral medicine, oral pathology and oral radiology vol. (2021). doi: https://doi.org/10.1016/j.oooo.2021.08.003
Karasneh J, Christoforou J, Walker JS, Dios PD, Lockhart PB, Patton LL. World Workshop on Oral Medicine VII: Bleeding control interventions for invasive dental procedures in patients with inherited functional platelet disorders: A systematic review. Oral Surg Oral Med Oral Pathol Oral Radiol. 2021 Aug 14; doi: 10.1016/j.oooo.2021.08.003. Epub 2021 Aug 14. PMID: 34758941.
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Genetic heterogeneity of polymicrogyria: study of 123 patients using deep sequencing.

Brain communications

Stutterd CA, Brock S, Stouffs K, Fanjul-Fernandez M, Lockhart PJ, McGillivray G, Mandelstam S, Pope K, Delatycki MB, Jansen A, Leventer RJ.
PMID: 33604570
Brain Commun. 2020 Dec 26;3(1):fcaa221. doi: 10.1093/braincomms/fcaa221. eCollection 2021.

Polymicrogyria is a malformation of cortical development characterized by overfolding and abnormal lamination of the cerebral cortex. Manifestations include epilepsy, speech disturbance and motor and cognitive disability. Causes include acquired prenatal insults and inherited and

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Stutterd CA, Brock S, Stouffs K, et al. Genetic heterogeneity of polymicrogyria: study of 123 patients using deep sequencing. Brain Commun. 2020;3(1):fcaa221doi: 10.1093/braincomms/fcaa221.
Stutterd, C. A., Brock, S., Stouffs, K., Fanjul-Fernandez, M., Lockhart, P. J., McGillivray, G., Mandelstam, S., Pope, K., Delatycki, M. B., Jansen, A., & Leventer, R. J. (2021). Genetic heterogeneity of polymicrogyria: study of 123 patients using deep sequencing. Brain communications, 3(1), fcaa221. https://doi.org/10.1093/braincomms/fcaa221
Stutterd, Chloe A, et al. "Genetic heterogeneity of polymicrogyria: study of 123 patients using deep sequencing." Brain communications vol. 3,1 (2021): fcaa221. doi: https://doi.org/10.1093/braincomms/fcaa221
Stutterd CA, Brock S, Stouffs K, Fanjul-Fernandez M, Lockhart PJ, McGillivray G, Mandelstam S, Pope K, Delatycki MB, Jansen A, Leventer RJ. Genetic heterogeneity of polymicrogyria: study of 123 patients using deep sequencing. Brain Commun. 2020 Dec 26;3(1):fcaa221. doi: 10.1093/braincomms/fcaa221. eCollection 2021. PMID: 33604570; PMCID: PMC7878248.
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Molecular characteristics and clinical outcomes of patients with Neurofibromin 1-altered metastatic colorectal cancer.

Oncogene

Arai H, Elliott A, Millstein J, Xiu J, Ou FS, Innocenti F, Wang J, Battaglin F, Jayachandran P, Kawanishi N, Soni S, Zhang W, Sohal D, Goldberg RM, Hall MJ, Scott AJ, Khushman M, Hwang JJ, Lou E, Weinberg BA, Lockhart AC, Shields AF, Abraham JP, Magee D, Stafford P, Zhang J, Venook AP, Korn WM, Lenz HJ.
PMID: 34728807
Oncogene. 2022 Jan;41(2):260-267. doi: 10.1038/s41388-021-02074-z. Epub 2021 Nov 02.

Loss-of-function alterations of Neurofibromin 1 (NF1) activate RAS, a driver of colorectal cancer. However, the clinical implications of NF1 alterations are largely unknown. We performed a comprehensive molecular profiling of NF1-mutant colorectal cancer using data from 8150 patients included...

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Arai H, Elliott A, Millstein J, et al. Molecular characteristics and clinical outcomes of patients with Neurofibromin 1-altered metastatic colorectal cancer. Oncogene. 2021;41(2):260-267doi: 10.1038/s41388-021-02074-z.
Arai, H., Elliott, A., Millstein, J., Xiu, J., Ou, F. S., Innocenti, F., Wang, J., Battaglin, F., Jayachandran, P., Kawanishi, N., Soni, S., Zhang, W., Sohal, D., Goldberg, R. M., Hall, M. J., Scott, A. J., Khushman, M., Hwang, J. J., Lou, E., Weinberg, B. A., Lockhart, A. C., Shields, A. F., Abraham, J. P., Magee, D., Stafford, P., Zhang, J., Venook, A. P., Korn, W. M., & Lenz, H. J. (2022). Molecular characteristics and clinical outcomes of patients with Neurofibromin 1-altered metastatic colorectal cancer. Oncogene, 41(2), 260-267. https://doi.org/10.1038/s41388-021-02074-z
Arai, Hiroyuki, et al. "Molecular characteristics and clinical outcomes of patients with Neurofibromin 1-altered metastatic colorectal cancer." Oncogene vol. 41,2 (2022): 260-267. doi: https://doi.org/10.1038/s41388-021-02074-z
Arai H, Elliott A, Millstein J, Xiu J, Ou FS, Innocenti F, Wang J, Battaglin F, Jayachandran P, Kawanishi N, Soni S, Zhang W, Sohal D, Goldberg RM, Hall MJ, Scott AJ, Khushman M, Hwang JJ, Lou E, Weinberg BA, Lockhart AC, Shields AF, Abraham JP, Magee D, Stafford P, Zhang J, Venook AP, Korn WM, Lenz HJ. Molecular characteristics and clinical outcomes of patients with Neurofibromin 1-altered metastatic colorectal cancer. Oncogene. 2022 Jan;41(2):260-267. doi: 10.1038/s41388-021-02074-z. Epub 2021 Nov 02. PMID: 34728807.
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A family study implicates GBE1 in the etiology of autism spectrum disorder.

Human mutation

Fanjul-Fernández M, Brown NJ, Hickey P, Diakumis P, Rafehi H, Bozaoglu K, Green CC, Rattray A, Young S, Alhuzaimi D, Mountford HS, Gillies G, Lukic V, Vick T, Finlay K, Coe BP, Eichler EE, Delatycki MB, Wilson SJ, Bahlo M, Scheffer IE, Lockhart PJ.
PMID: 34633740
Hum Mutat. 2022 Jan;43(1):16-29. doi: 10.1002/humu.24289. Epub 2021 Oct 21.

Autism spectrum disorders (ASD) are neurodevelopmental disorders with an estimated heritability of >60%. Family-based genetic studies of ASD have generally focused on multiple small kindreds, searching for de novo variants of major effect. We hypothesized that molecular genetic analysis...

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Fanjul-Fernández M, Brown NJ, Hickey P, et al. A family study implicates GBE1 in the etiology of autism spectrum disorder. Hum Mutat. 2021;43(1):16-29doi: 10.1002/humu.24289.
Fanjul-Fernández, M., Brown, N. J., Hickey, P., Diakumis, P., Rafehi, H., Bozaoglu, K., Green, C. C., Rattray, A., Young, S., Alhuzaimi, D., Mountford, H. S., Gillies, G., Lukic, V., Vick, T., Finlay, K., Coe, B. P., Eichler, E. E., Delatycki, M. B., Wilson, S. J., Bahlo, M., Scheffer, I. E., & Lockhart, P. J. (2022). A family study implicates GBE1 in the etiology of autism spectrum disorder. Human mutation, 43(1), 16-29. https://doi.org/10.1002/humu.24289
Fanjul-Fernández, Miriam, et al. "A family study implicates GBE1 in the etiology of autism spectrum disorder." Human mutation vol. 43,1 (2022): 16-29. doi: https://doi.org/10.1002/humu.24289
Fanjul-Fernández M, Brown NJ, Hickey P, Diakumis P, Rafehi H, Bozaoglu K, Green CC, Rattray A, Young S, Alhuzaimi D, Mountford HS, Gillies G, Lukic V, Vick T, Finlay K, Coe BP, Eichler EE, Delatycki MB, Wilson SJ, Bahlo M, Scheffer IE, Lockhart PJ. A family study implicates GBE1 in the etiology of autism spectrum disorder. Hum Mutat. 2022 Jan;43(1):16-29. doi: 10.1002/humu.24289. Epub 2021 Oct 21. PMID: 34633740; PMCID: PMC8720068.
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Resection of tuber centers only for seizure control in tuberous sclerosis complex.

Epilepsy research

Stephenson SEM, Maixner WJ, Barton SM, D'Arcy C, Mandelstam SA, MacGregor D, Lockhart PJ, Leventer RJ, Harvey AS.
PMID: 33662678
Epilepsy Res. 2021 Mar;171:106572. doi: 10.1016/j.eplepsyres.2021.106572. Epub 2021 Feb 08.

Our previous studies suggest the tuber center is the seizure focus in tuberous sclerosis complex (TSC). We report findings from 5 epilepsy surgeries in 4 children with TSC and focal motor seizures from single tubers in primary sensorimotor cortex...

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Stephenson SEM, Maixner WJ, Barton SM, et al. Resection of tuber centers only for seizure control in tuberous sclerosis complex. Epilepsy Res. 2021;171:106572doi: 10.1016/j.eplepsyres.2021.106572.
Stephenson, S. E. M., Maixner, W. J., Barton, S. M., D'Arcy, C., Mandelstam, S. A., MacGregor, D., Lockhart, P. J., Leventer, R. J., & Harvey, A. S. (2021). Resection of tuber centers only for seizure control in tuberous sclerosis complex. Epilepsy research, 171106572. https://doi.org/10.1016/j.eplepsyres.2021.106572
Stephenson, Sarah E M, et al. "Resection of tuber centers only for seizure control in tuberous sclerosis complex." Epilepsy research vol. 171 (2021): 106572. doi: https://doi.org/10.1016/j.eplepsyres.2021.106572
Stephenson SEM, Maixner WJ, Barton SM, D'Arcy C, Mandelstam SA, MacGregor D, Lockhart PJ, Leventer RJ, Harvey AS. Resection of tuber centers only for seizure control in tuberous sclerosis complex. Epilepsy Res. 2021 Mar;171:106572. doi: 10.1016/j.eplepsyres.2021.106572. Epub 2021 Feb 08. PMID: 33662678.
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Experiences of stigma in hospitals with addiction consultation services: A qualitative analysis of patients' and hospital-based providers' perspectives.

Journal of substance abuse treatment

Hoover K, Lockhart S, Callister C, Holtrop JS, Calcaterra SL.
PMID: 34991950
J Subst Abuse Treat. 2021 Dec 27;108708. doi: 10.1016/j.jsat.2021.108708. Epub 2021 Dec 27.

BACKGROUND: Addiction consultation services (ACS) provide evidence-based treatment to hospitalized patients with substance use disorders (SUD). Expansion of hospital-based addiction care may help to counteract the stigma that patients with SUD experience within the health care system. Stigma is...

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Hoover K, Lockhart S, Callister C, et al. Experiences of stigma in hospitals with addiction consultation services: A qualitative analysis of patients' and hospital-based providers' perspectives. J Subst Abuse Treat. 2021;108708doi: 10.1016/j.jsat.2021.108708.
Hoover, K., Lockhart, S., Callister, C., Holtrop, J. S., & Calcaterra, S. L. (2021). Experiences of stigma in hospitals with addiction consultation services: A qualitative analysis of patients' and hospital-based providers' perspectives. Journal of substance abuse treatment, 108708. https://doi.org/10.1016/j.jsat.2021.108708
Hoover, Kaitlyn, et al. "Experiences of stigma in hospitals with addiction consultation services: A qualitative analysis of patients' and hospital-based providers' perspectives." Journal of substance abuse treatment vol. (2021): 108708. doi: https://doi.org/10.1016/j.jsat.2021.108708
Hoover K, Lockhart S, Callister C, Holtrop JS, Calcaterra SL. Experiences of stigma in hospitals with addiction consultation services: A qualitative analysis of patients' and hospital-based providers' perspectives. J Subst Abuse Treat. 2021 Dec 27;108708. doi: 10.1016/j.jsat.2021.108708. Epub 2021 Dec 27. PMID: 34991950.
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Paraneoplastic neurologic syndromes with multiple neural autoantibodies: A report of two cases.

Journal of neuroimmunology

Lockhart A, Boers P.
PMID: 34329983
J Neuroimmunol. 2021 Sep 15;358:577665. doi: 10.1016/j.jneuroim.2021.577665. Epub 2021 Jul 15.

We present two patients who presented with classical paraneoplastic syndromes with multiple central nervous system (CNS) autoantibodies in each case. The presence of multiple antibodies made the detection of a malignancy more likely and both patients were subsequently diagnosed...

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Lockhart A, Boers P. Paraneoplastic neurologic syndromes with multiple neural autoantibodies: A report of two cases. J Neuroimmunol. 2021;358:577665doi: 10.1016/j.jneuroim.2021.577665.
Lockhart, A., & Boers, P. (2021). Paraneoplastic neurologic syndromes with multiple neural autoantibodies: A report of two cases. Journal of neuroimmunology, 358577665. https://doi.org/10.1016/j.jneuroim.2021.577665
Lockhart, Andrew, and Boers, Peter. "Paraneoplastic neurologic syndromes with multiple neural autoantibodies: A report of two cases." Journal of neuroimmunology vol. 358 (2021): 577665. doi: https://doi.org/10.1016/j.jneuroim.2021.577665
Lockhart A, Boers P. Paraneoplastic neurologic syndromes with multiple neural autoantibodies: A report of two cases. J Neuroimmunol. 2021 Sep 15;358:577665. doi: 10.1016/j.jneuroim.2021.577665. Epub 2021 Jul 15. PMID: 34329983.
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Showing 253 to 262 of 262 entries