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Showing 25 to 36 of 201 entries
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Tyrosine kinase inhibitors as next generation oncological therapeutics: Current strategies, limitations and future perspectives.

Therapie

Shinde A, Panchal K, Katke S, Paliwal R, Chaurasiya A.
PMID: 34823895
Therapie. 2021 Nov 02; doi: 10.1016/j.therap.2021.10.010. Epub 2021 Nov 02.

Protein kinases, a class of enzymes that govern various biological phenomena at a cellular level, are responsible for signal transduction in cells that regulate cellular proliferation, differentiation, and growth. Protein kinase enzyme mutation results in abnormal cell division leading...

Atlas-based auto-segmentation for delineating the heart and cardiac substructures in breast cancer radiation therapy.

Acta oncologica (Stockholm, Sweden)

Milo MLH, Nyeng TB, Lorenzen EL, Hoffmann L, Møller DS, Offersen BV.
PMID: 34427497
Acta Oncol. 2021 Aug 24;1-8. doi: 10.1080/0284186X.2021.1967445. Epub 2021 Aug 24.

BACKGROUND: This study aimed to develop and validate an automatic multi-atlas segmentation method for delineating the heart and substructures in breast cancer radiation therapy (RT).MATERIAL AND METHODS: The atlas database consisted of non-contrast-enhanced planning CT scans from 42 breast...

Relaxation dynamics of Pd-Ni-P metallic glass: decoupling of anelastic and viscous processes.

Journal of physics. Condensed matter : an Institute of Physics journal

Soriano D, Zhou H, Hilke S, Pineda E, Ruta B, Wilde G.
PMID: 33725689
J Phys Condens Matter. 2021 Apr 20;33(16). doi: 10.1088/1361-648X/abef27.

The stress relaxation dynamics of metallic glass Pd

Training of healthcare providers and use of long-acting reversible contraception in low- and middle-income countries: A systematic review.

Acta obstetricia et gynecologica Scandinavica

Stokholm Baekgaard R, Gjaerevold Damhaugh E, Mrema D, Rasch V, Khan K, Linde DS.
PMID: 33594675
Acta Obstet Gynecol Scand. 2021 Apr;100(4):619-628. doi: 10.1111/aogs.14127. Epub 2021 Mar 16.

INTRODUCTION: Unintended pregnancy, a major global health issue resulting in unsafe terminations of pregnancy and maternal deaths in low- and middle-income countries, could be significantly reduced through increased use of modern contraception, including long-acting reversible contraceptives (LARC). Training of...

Cross-Format Integration of Auditory Number Words and Visual-Arabic Digits: An ERP Study.

Frontiers in psychology

Finke S, Kemény F, Clayton FJ, Banfi C, Steiner AF, Perchtold-Stefan CM, Papousek I, Göbel SM, Landerl K.
PMID: 34887813
Front Psychol. 2021 Nov 23;12:765709. doi: 10.3389/fpsyg.2021.765709. eCollection 2021.

Converting visual-Arabic digits to auditory number words and vice versa is seemingly effortless for adults. However, it is still unclear whether this process takes place automatically and whether accessing the underlying magnitude representation is necessary during this process. In...

Effects of an open lung ventilatory strategy on lung gas exchange during laparoscopic surgery.

Anaesthesia and intensive care

Peyton PJ, Aitken S, Wallin M.
PMID: 34871514
Anaesth Intensive Care. 2021 Dec 06;310057X211047602. doi: 10.1177/0310057X211047602. Epub 2021 Dec 06.

In general anaesthesia, early collapse of poorly ventilated lung segments with low alveolar ventilation-perfusion ratios occurs and may lead to postoperative pulmonary complications after abdominal surgery. An 'open lung' ventilation strategy involves lung recruitment followed by 'individualised' positive end-expiratory...

Nucleolar stress controls mutant Huntington toxicity and monitors Huntington's disease progression.

Cell death & disease

Sönmez A, Mustafa R, Ryll ST, Tuorto F, Wacheul L, Ponti D, Litke C, Hering T, Kojer K, Koch J, Pitzer C, Kirsch J, Neueder A, Kreiner G, Lafontaine DLJ, Orth M, Liss B, Parlato R.
PMID: 34880223
Cell Death Dis. 2021 Dec 08;12(12):1139. doi: 10.1038/s41419-021-04432-x.

Transcriptional and cellular-stress surveillance deficits are hallmarks of Huntington's disease (HD), a fatal autosomal-dominant neurodegenerative disorder caused by a pathological expansion of CAG repeats in the Huntingtin (HTT) gene. The nucleolus, a dynamic nuclear biomolecular condensate and the site...

Public sensemaking of active packaging technologies: A feature-based perspective.

Public understanding of science (Bristol, England)

Festila A, Chrysochou P, Hieke S, Massri C.
PMID: 34053362
Public Underst Sci. 2021 Nov;30(8):1024-1040. doi: 10.1177/09636625211015830. Epub 2021 May 31.

Taking a point of departure in the idea that technology features can act as cues for sensemaking, we explore how the public makes sense of new active packaging technologies; technologies that absorb or release substances from or into the...

Second harmonic generation on chiral cyanido-bridged Fe.

Dalton transactions (Cambridge, England : 2003)

Kawabata S, Nakabayashi K, Imoto K, Klimke S, Renz F, Ohkoshi SI.
PMID: 34075991
Dalton Trans. 2021 Jun 22;50(24):8524-8532. doi: 10.1039/d1dt01324f.

Incorporating chiral organic ligands into cyanido-bridged FeII-NbIV assemblies synthesized chiral spin-crossover complexes, FeII2[NbIV(CN)8](L)8·6H2O (L = R-, S-, or rac-1-(3-pyridyl)ethanol: R-FeNb, S-FeNb, or rac-FeNb). Rietveld analyses based on a racemic complex of rac-FeNb indicate that the chiral complexes have a...

The structure of unliganded sterol carrier protein 2 from Yarrowia lipolytica unveils a mechanism for binding site occlusion.

Journal of structural biology

Gianotti AR, Klinke S, Ermácora MR.
PMID: 33278583
J Struct Biol. 2021 Mar;213(1):107675. doi: 10.1016/j.jsb.2020.107675. Epub 2020 Dec 02.

Isolated or as a part of multidomain proteins, Sterol Carrier Protein 2 (SCP2) exhibits high affinity and broad specificity for different lipidic and hydrophobic compounds. A wealth of structural information on SCP2 domains in all forms of life is...

Assessment of Gastrointestinal Autonomic Dysfunction: Present and Future Perspectives.

Journal of clinical medicine

Kornum DS, Terkelsen AJ, Bertoli D, Klinge MW, Høyer KL, Kufaishi HHA, Borghammer P, Drewes AM, Brock C, Krogh K.
PMID: 33807256
J Clin Med. 2021 Mar 31;10(7). doi: 10.3390/jcm10071392.

The autonomic nervous system delicately regulates the function of several target organs, including the gastrointestinal tract. Thus, nerve lesions or other nerve pathologies may cause autonomic dysfunction (AD). Some of the most common causes of AD are diabetes mellitus...

Author Correction: Interaction between the microbiome and TP53 in human lung cancer.

Genome biology

Greathouse KL, White JR, Vargas AJ, Bliskovsky VV, Beck JA, von Muhlinen N, Polley EC, Bowman ED, Khan MA, Robles AI, Cooks T, Ryan BM, Padgett N, Dzutsev AH, Trinchieri G, Pineda MA, Bilke S, Meltzer PS, Hokenstad AN, Stickrod TM, Walther-Antonio MR, Earl JP, Mell JC, Krol JE, Balashov SV, Bhat AS, Ehrlich GD, Valm A, Deming C, Conlan S, Oh J, Segre JA, Harris CC.
PMID: 32079537
Genome Biol. 2020 Feb 20;21(1):41. doi: 10.1186/s13059-020-01961-0.

Following publication of the original paper [1], the authors submitted a new Additional file 5 to replace the one containing formatting issues. The updated Additional file 5 is published in this correction.

Showing 25 to 36 of 201 entries