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Metformin-Incorporated Gelatin/Nano-Hydroxyapatite Scaffolds Promotes Bone Regeneration in Critical Size Rat Alveolar Bone Defect Model.

International journal of molecular sciences

Fang CH, Sun CK, Lin YW, Hung MC, Lin HY, Li CH, Lin IP, Chang HC, Sun JS, Chang JZ.
PMID: 35008984
Int J Mol Sci. 2022 Jan 05;23(1). doi: 10.3390/ijms23010558.

In this study, we fabricated gelatin/nano-hydroxyapatite/metformin scaffold (GHMS) and compared its effectiveness in bone regeneration with extraction-only, Sinbone, and Bio-Oss Collagen

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Fang CH, Sun CK, Lin YW, et al. Metformin-Incorporated Gelatin/Nano-Hydroxyapatite Scaffolds Promotes Bone Regeneration in Critical Size Rat Alveolar Bone Defect Model. Int J Mol Sci. 2022;23(1)doi: 10.3390/ijms23010558.
Fang, C. H., Sun, C. K., Lin, Y. W., Hung, M. C., Lin, H. Y., Li, C. H., Lin, I. P., Chang, H. C., Sun, J. S., & Chang, J. Z. (2022). Metformin-Incorporated Gelatin/Nano-Hydroxyapatite Scaffolds Promotes Bone Regeneration in Critical Size Rat Alveolar Bone Defect Model. International journal of molecular sciences, 23(1), . https://doi.org/10.3390/ijms23010558
Fang, Chih-Hsiang, et al. "Metformin-Incorporated Gelatin/Nano-Hydroxyapatite Scaffolds Promotes Bone Regeneration in Critical Size Rat Alveolar Bone Defect Model." International journal of molecular sciences vol. 23,1 (2022). doi: https://doi.org/10.3390/ijms23010558
Fang CH, Sun CK, Lin YW, Hung MC, Lin HY, Li CH, Lin IP, Chang HC, Sun JS, Chang JZ. Metformin-Incorporated Gelatin/Nano-Hydroxyapatite Scaffolds Promotes Bone Regeneration in Critical Size Rat Alveolar Bone Defect Model. Int J Mol Sci. 2022 Jan 05;23(1). doi: 10.3390/ijms23010558. PMID: 35008984.
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Positive allosteric modulation of the mu-opioid receptor produces analgesia with reduced side effects.

Proceedings of the National Academy of Sciences of the United States of America

Kandasamy R, Hillhouse TM, Livingston KE, Kochan KE, Meurice C, Eans SO, Li MH, White AD, Roques BP, McLaughlin JP, Ingram SL, Burford NT, Alt A, Traynor JR.
PMID: 33846240
Proc Natl Acad Sci U S A. 2021 Apr 20;118(16). doi: 10.1073/pnas.2000017118.

Positive allosteric modulators (PAMs) of the mu-opioid receptor (MOR) have been hypothesized as potentially safer analgesics than traditional opioid drugs. This is based on the idea that PAMs will promote the action of endogenous opioid peptides while preserving their...

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Kandasamy R, Hillhouse TM, Livingston KE, et al. Positive allosteric modulation of the mu-opioid receptor produces analgesia with reduced side effects. Proc Natl Acad Sci U S A. 2021;118(16)doi: 10.1073/pnas.2000017118.
Kandasamy, R., Hillhouse, T. M., Livingston, K. E., Kochan, K. E., Meurice, C., Eans, S. O., Li, M. H., White, A. D., Roques, B. P., McLaughlin, J. P., Ingram, S. L., Burford, N. T., Alt, A., & Traynor, J. R. (2021). Positive allosteric modulation of the mu-opioid receptor produces analgesia with reduced side effects. Proceedings of the National Academy of Sciences of the United States of America, 118(16), . https://doi.org/10.1073/pnas.2000017118
Kandasamy, Ram, et al. "Positive allosteric modulation of the mu-opioid receptor produces analgesia with reduced side effects." Proceedings of the National Academy of Sciences of the United States of America vol. 118,16 (2021). doi: https://doi.org/10.1073/pnas.2000017118
Kandasamy R, Hillhouse TM, Livingston KE, Kochan KE, Meurice C, Eans SO, Li MH, White AD, Roques BP, McLaughlin JP, Ingram SL, Burford NT, Alt A, Traynor JR. Positive allosteric modulation of the mu-opioid receptor produces analgesia with reduced side effects. Proc Natl Acad Sci U S A. 2021 Apr 20;118(16). doi: 10.1073/pnas.2000017118. PMID: 33846240; PMCID: PMC8072371.
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Human carboxylesterase 1A plays a predominant role in the hydrolytic activation of remdesivir in humans.

Chemico-biological interactions

Zhang F, Li HX, Zhang TT, Xiong Y, Wang HN, Lu ZH, Xiong L, He YQ, Ge GB.
PMID: 34774545
Chem Biol Interact. 2021 Nov 11;351:109744. doi: 10.1016/j.cbi.2021.109744. Epub 2021 Nov 11.

Remdesivir, an intravenous nucleotide prodrug, has been approved for treating COVID-19 in hospitalized adults and pediatric patients. Upon administration, remdesivir can be readily hydrolyzed to form its active form GS-441524, while the cleavage of the carboxylic ester into GS-704277...

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Zhang F, Li HX, Zhang TT, et al. Human carboxylesterase 1A plays a predominant role in the hydrolytic activation of remdesivir in humans. Chem Biol Interact. 2021;351:109744doi: 10.1016/j.cbi.2021.109744.
Zhang, F., Li, H. X., Zhang, T. T., Xiong, Y., Wang, H. N., Lu, Z. H., Xiong, L., He, Y. Q., & Ge, G. B. (2021). Human carboxylesterase 1A plays a predominant role in the hydrolytic activation of remdesivir in humans. Chemico-biological interactions, 351109744. https://doi.org/10.1016/j.cbi.2021.109744
Zhang, Feng, et al. "Human carboxylesterase 1A plays a predominant role in the hydrolytic activation of remdesivir in humans." Chemico-biological interactions vol. 351 (2021): 109744. doi: https://doi.org/10.1016/j.cbi.2021.109744
Zhang F, Li HX, Zhang TT, Xiong Y, Wang HN, Lu ZH, Xiong L, He YQ, Ge GB. Human carboxylesterase 1A plays a predominant role in the hydrolytic activation of remdesivir in humans. Chem Biol Interact. 2021 Nov 11;351:109744. doi: 10.1016/j.cbi.2021.109744. Epub 2021 Nov 11. PMID: 34774545.
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Highly sensitive novel fluorescent chiral probe possessing (S)-2-methylproline structures for the determination of chiral amino compounds by ultra-performance liquid chromatography with fluorescence: An application in the saliva of healthy volunteer.

Journal of chromatography. A

Li XL, Han Y, Huang Y, Sun X, Xiao S, Min JZ.
PMID: 34896695
J Chromatogr A. 2021 Nov 14;1661:462672. doi: 10.1016/j.chroma.2021.462672. Epub 2021 Nov 14.

We developed a novel fluorescent chiral probe, DBD-trans-2-methyl-L-proline (DBD-M-Pro), which can be used to target recognition of amino functional groups using chiral resolution. To investigate the chiral resolution efficiency, 20 chiral amino enantiomers (19 DL-amino acids and phenylethylamine) were...

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Li XL, Han Y, Huang Y, et al. Highly sensitive novel fluorescent chiral probe possessing (S)-2-methylproline structures for the determination of chiral amino compounds by ultra-performance liquid chromatography with fluorescence: An application in the saliva of healthy volunteer. J Chromatogr A. 2021;1661:462672doi: 10.1016/j.chroma.2021.462672.
Li, X. L., Han, Y., Huang, Y., Sun, X., Xiao, S., & Min, J. Z. (2021). Highly sensitive novel fluorescent chiral probe possessing (S)-2-methylproline structures for the determination of chiral amino compounds by ultra-performance liquid chromatography with fluorescence: An application in the saliva of healthy volunteer. Journal of chromatography. A, 1661462672. https://doi.org/10.1016/j.chroma.2021.462672
Li, Xi-Ling, et al. "Highly sensitive novel fluorescent chiral probe possessing (S)-2-methylproline structures for the determination of chiral amino compounds by ultra-performance liquid chromatography with fluorescence: An application in the saliva of healthy volunteer." Journal of chromatography. A vol. 1661 (2021): 462672. doi: https://doi.org/10.1016/j.chroma.2021.462672
Li XL, Han Y, Huang Y, Sun X, Xiao S, Min JZ. Highly sensitive novel fluorescent chiral probe possessing (S)-2-methylproline structures for the determination of chiral amino compounds by ultra-performance liquid chromatography with fluorescence: An application in the saliva of healthy volunteer. J Chromatogr A. 2021 Nov 14;1661:462672. doi: 10.1016/j.chroma.2021.462672. Epub 2021 Nov 14. PMID: 34896695.
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Effective Renal Clearance and Photothermal Therapy of a Cyclodextrin-Modified Quaterrylene Derivative.

ACS applied bio materials

Luo YL, Rong RX, Li JM, Chen X, Wang SS, Li XL, Wang KR.
PMID: 35025381
ACS Appl Bio Mater. 2020 May 18;3(5):3390-3400. doi: 10.1021/acsabm.0c00311. Epub 2020 May 06.

Metabolic clearance of drugs from the body is a key element for future clinical applications. Compared with the liver-bile metabolic route, the renal-urinary route is the most desirable and efficient clearance pathway for practical use in clinical trials and...

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Luo YL, Rong RX, Li JM, et al. Effective Renal Clearance and Photothermal Therapy of a Cyclodextrin-Modified Quaterrylene Derivative. ACS Appl Bio Mater. 2020;3(5):3390-3400doi: 10.1021/acsabm.0c00311.
Luo, Y. L., Rong, R. X., Li, J. M., Chen, X., Wang, S. S., Li, X. L., & Wang, K. R. (2020). Effective Renal Clearance and Photothermal Therapy of a Cyclodextrin-Modified Quaterrylene Derivative. ACS applied bio materials, 3(5), 3390-3400. https://doi.org/10.1021/acsabm.0c00311
Luo, Ya-Li, et al. "Effective Renal Clearance and Photothermal Therapy of a Cyclodextrin-Modified Quaterrylene Derivative." ACS applied bio materials vol. 3,5 (2020): 3390-3400. doi: https://doi.org/10.1021/acsabm.0c00311
Luo YL, Rong RX, Li JM, Chen X, Wang SS, Li XL, Wang KR. Effective Renal Clearance and Photothermal Therapy of a Cyclodextrin-Modified Quaterrylene Derivative. ACS Appl Bio Mater. 2020 May 18;3(5):3390-3400. doi: 10.1021/acsabm.0c00311. Epub 2020 May 06. PMID: 35025381.
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Educating Cancer Prevention Researchers in Emerging Biobehavioral Models: Lessons Learned.

Chang S, Cameron C, Correa-Fernandez V, Davila M, Kamrudin SA, Li DH, Noor SW, Oluyomi AO.
UIID-AD: 396
2011;26:633-640. doi: 10.1007/s13187-011-0251-x.

To increase the adoption of transdisciplinary research methods among future cancer prevention investigators, faculty members from The University of Texas MD Anderson Cancer Center developed a graduate-level course in biobehavioral methods in cancer prevention research. Two instructors paired by...

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Chang S, Cameron C, Correa-Fernandez V, et al. Educating Cancer Prevention Researchers in Emerging Biobehavioral Models: Lessons Learned. 2011;26:633-640doi: 10.1007/s13187-011-0251-x.
Chang, S., Cameron, C., Correa-Fernandez, V., Davila, M., Kamrudin, S. A., Li, D. H., Noor, S. W., & Oluyomi, A. O. (2011). Educating Cancer Prevention Researchers in Emerging Biobehavioral Models: Lessons Learned. 26633-640. https://doi.org/10.1007/s13187-011-0251-x
Chang, S, et al. "Educating Cancer Prevention Researchers in Emerging Biobehavioral Models: Lessons Learned." vol. 26 (2011): 633-640. doi: https://doi.org/10.1007/s13187-011-0251-x
Chang S, Cameron C, Correa-Fernandez V, Davila M, Kamrudin SA, Li DH, Noor SW, Oluyomi AO. Educating Cancer Prevention Researchers in Emerging Biobehavioral Models: Lessons Learned. 2011;26:633-640. doi: 10.1007/s13187-011-0251-x. UIID-AD: 396.
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Showing 7585 to 7590 of 7590 entries