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Showing 13 to 24 of 54 entries
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Long-term disease control of a pancreatic neuroendocrine tumor with lanreotide autogel(®): a case report.

Case reports in oncology

Lybaert W, Van Hul E, Woestenborghs H.
PMID: 25408662
Case Rep Oncol. 2014 Sep 26;7(3):673-80. doi: 10.1159/000368207. eCollection 2014 Sep.

The CLARINET study (ClinicalTrials.gov: NCT00353496) showed that somatostatin analogs are able to stabilize tumor growth in patients with intestinal and pancreatic neuroendocrine tumors (NETs). Here, we present a case of NET originating from the pancreatic tail that was treated...

Multidisciplinary molecular tumour board: a tool to improve clinical practice and selection accrual for clinical trials in patients with cancer.

ESMO open

Rolfo C, Manca P, Salgado R, Van Dam P, Dendooven A, Ferri Gandia J, Rutten A, Lybaert W, Vermeij J, Gevaert T, Weyn C, Lefebure A, Metsu S, Van Laere S, Peeters M, Pauwels P, Machado Coelho A.
PMID: 30094075
ESMO Open. 2018 Jul 23;3(5):e000398. doi: 10.1136/esmoopen-2018-000398. eCollection 2018.

BACKGROUND: The complexity of delivering precision medicine to oncology patients has led to the creation of molecular tumourboards (MTBs) for patient selection and assessment of treatment options. New technologies like the liquid biopsy are augmenting available therapeutic opportunities. This...

Versatile Loading of Diverse Cargo into Functional Polymer Capsules.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Richardson JJ, Maina JW, Ejima H, Hu M, Guo J, Choy MY, Gunawan ST, Lybaert L, Hagemeyer CE, De Geest BG, Caruso F.
PMID: 27980899
Adv Sci (Weinh). 2015 Jan 29;2(1):1400007. doi: 10.1002/advs.201400007. eCollection 2015 Feb.

Polymer microcapsules are of particular interest for applications including self-healing coatings, catalysis, bioreactions, sensing, and drug delivery. The primary way that polymer capsules can exhibit functionality relevant to these diverse fields is through the incorporation of functional cargo in...

Connexin and pannexin (hemi)channels in the liver.

Frontiers in physiology

Maes M, Decrock E, Cogliati B, Oliveira AG, Marques PE, Dagli ML, Menezes GB, Mennecier G, Leybaert L, Vanhaecke T, Rogiers V, Vinken M.
PMID: 24454290
Front Physiol. 2014 Jan 10;4:405. doi: 10.3389/fphys.2013.00405. eCollection 2014 Jan 10.

The liver was among the first organs in which connexin proteins have been identified. Hepatocytes harbor connexin32 and connexin26, while non-parenchymal liver cells typically express connexin43. Connexins give rise to hemichannels, which dock with counterparts on adjacent cells to...

The silica balance in the world ocean: a reestimate.

Science (New York, N.Y.)

Tréguer P, Nelson DM, Van Bennekom AJ, Demaster DJ, Leynaert A, Quéguiner B.
PMID: 17746543
Science. 1995 Apr 21;268(5209):375-9. doi: 10.1126/science.268.5209.375.

The net inputs of silicic acid (dissolved silica) to the world ocean have been revised to 6.1 +/- 2.0 teramoles of silicon per year (1 teramole = 10(12) moles). The major contribution (about 80 percent) comes from rivers, whose...

A simple and practical method to acquire geometrically correct images with resonant scanning-based line scanning in a custom-built video-rate laser scanning microscope.

Journal of microscopy

Leybaert L, de Meyer A, Mabilde C, Sanderson MJ.
PMID: 16176253
J Microsc. 2005 Sep;219:133-40. doi: 10.1111/j.1365-2818.2005.01502.x.

Most currently available confocal or two-photon laser scanning microscopes (LSMs) allow acquisition rates of the order of 1-5 images s(-1), which is too slow to fully resolve dynamic changes in intracellular messenger concentration in living cells or tissues. Several...

Rapamycin prevents mesenteric neo-angiogenesis and reduces splanchnic blood flow in portal hypertensive mice.

Hepatology research : the official journal of the Japan Society of Hepatology

Geerts AM, Vanheule E, Van Vlierberghe H, Leybaert L, Van Steenkiste C, De Vos M, Colle I.
PMID: 18564143
Hepatol Res. 2008;38(11):1130-9. doi: 10.1111/j.1872-034X.2008.00369.x. Epub 2008 Jun 17.

AIM: Increased angiogenesis in the mesenteric microvasculature of portal hypertensive animals may contribute to the development of splanchnic vasodilation associated with portal hypertension (PHT). Experimental data suggest that rapamycin may reduce angiogenesis and tumour growth by inhibiting the vascular...

Opening of pannexin- and connexin-based channels increases the excitability of nodose ganglion sensory neurons.

Frontiers in cellular neuroscience

Retamal MA, Alcayaga J, Verdugo CA, Bultynck G, Leybaert L, Sáez PJ, Fernández R, León LE, Sáez JC.
PMID: 24999316
Front Cell Neurosci. 2014 Jun 20;8:158. doi: 10.3389/fncel.2014.00158. eCollection 2014.

Satellite glial cells (SGCs) are the main glia in sensory ganglia. They surround neuronal bodies and form a cap that prevents the formation of chemical or electrical synapses between neighboring neurons. SGCs have been suggested to establish bidirectional paracrine...

Outdoor Mold and Respiratory Health: State of Science of Epidemiological Studies.

The journal of allergy and clinical immunology. In practice

Caillaud D, Keirsbulck M, Leger C, Leynaert B.
PMID: 34648953
J Allergy Clin Immunol Pract. 2021 Oct 11; doi: 10.1016/j.jaip.2021.09.042. Epub 2021 Oct 11.

BACKGROUND: Fungal spores are the predominant biological particulates in outdoor air. However, in contrast to pollens or outdoor air pollution, little is known about their respiratory health risks.OBJECTIVES: The objectives were to conduct the first review of epidemiological studies...

How is the McGurk effect modulated by Cued Speech in deaf and hearing adults?.

Frontiers in psychology

Bayard C, Colin C, Leybaert J.
PMID: 24904451
Front Psychol. 2014 May 19;5:416. doi: 10.3389/fpsyg.2014.00416. eCollection 2014.

Speech perception for both hearing and deaf people involves an integrative process between auditory and lip-reading information. In order to disambiguate information from lips, manual cues from Cued Speech may be added. Cued Speech (CS) is a system of...

Conserved Mechanism of Bicarbonate-Induced Sensitization of CatSper Channels in Human and Mouse Sperm.

Frontiers in cell and developmental biology

Ferreira JJ, Lybaert P, Puga-Molina LC, Santi CM.
PMID: 34650979
Front Cell Dev Biol. 2021 Sep 28;9:733653. doi: 10.3389/fcell.2021.733653. eCollection 2021.

To fertilize an egg, mammalian sperm must undergo capacitation in the female genital tract. A key contributor to capacitation is the calcium (Ca

Blood Cytokine Analysis Suggests That SARS-CoV-2 Infection Results in a Sustained Tumour Promoting Environment in Cancer Patients.

Cancers

De Winter FHR, Hotterbeekx A, Huizing MT, Konnova A, Fransen E, Jongers B, Jairam RK, Van Averbeke V, Moons P, Roelant E, Le Blon D, Vanden Berghe W, Janssens A, Lybaert W, Croes L, Vulsteke C, Malhotra-Kumar S, Goossens H, Berneman Z, Peeters M, van Dam PA, Kumar-Singh S.
PMID: 34830872
Cancers (Basel). 2021 Nov 15;13(22). doi: 10.3390/cancers13225718.

Cytokines, chemokines, and (angiogenic) growth factors (CCGs) have been shown to play an intricate role in the progression of both solid and haematological malignancies. Recent studies have shown that SARS-CoV-2 infection leads to a worse outcome in cancer patients,...

Showing 13 to 24 of 54 entries