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Showing 313 to 323 of 323 entries
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CXCR4 blockade reduces the severity of murine heart allograft rejection by plasmacytoid dendritic cell-mediated immune regulation.

Scientific reports

Fu J, Lehmann CHK, Wang X, Wahlbuhl M, Allabauer I, Wilde B, Amon L, Dolff S, Cesnjevar R, Kribben A, Woelfle J, Rascher W, Hoyer PF, Dudziak D, Witzke O, Hoerning A.
PMID: 34893663
Sci Rep. 2021 Dec 10;11(1):23815. doi: 10.1038/s41598-021-03115-z.

Allograft-specific regulatory T cells (T

Guillain-Barré syndrome.

Lancet (London, England)

Shahrizaila N, Lehmann HC, Kuwabara S.
PMID: 33647239
Lancet. 2021 Mar 27;397(10280):1214-1228. doi: 10.1016/S0140-6736(21)00517-1. Epub 2021 Feb 26.

Guillain-Barré syndrome is the most common cause of acute flaccid paralysis worldwide. Most patients present with an antecedent illness, most commonly upper respiratory tract infection, before the onset of progressive motor weakness. Several microorganisms have been associated with Guillain-Barré...

Impact of decreasing vancomycin exposure on acute kidney injury in stem cell transplant recipients.

Infection control and hospital epidemiology

Hambrick HR, Greco KF, Weller E, Ganapathi L, Lehmann LE, Sandora TJ.
PMID: 34874001
Infect Control Hosp Epidemiol. 2021 Dec 07;1-7. doi: 10.1017/ice.2021.454. Epub 2021 Dec 07.

OBJECTIVE: To evaluate the change in vancomycin days of therapy (DOT) and vancomycin-associated acute kidney injury (AKI) after an antimicrobial stewardship program (ASP) intervention to decrease vancomycin use in stable patients after hematopoietic stem cell transplantation (HSCT).DESIGN: Retrospective cohort...

[Literature review on pharmacovigilance of medicines derived from traditional pharmacopoeias. Part II: risks assessment and prevention].

Annales pharmaceutiques francaises

Ouoba K, Lehmann H, Pabst JY, Semde R.
PMID: 34896380
Ann Pharm Fr. 2021 Dec 09; doi: 10.1016/j.pharma.2021.11.007. Epub 2021 Dec 09.

After the initial stage of the pharmacovigilance process for medicines from traditional pharmacopoeias - which concerns the identification of the risks associated with their use - the risk assessment should now be approached. The latter makes it possible to...

[Literature review on pharmacovigilance of medicines derived from traditional pharmacopoeias. Part I: risks identification].

Annales pharmaceutiques francaises

Ouoba K, Lehmann H, Semde R, Pabst JY.
PMID: 34914891
Ann Pharm Fr. 2021 Dec 13; doi: 10.1016/j.pharma.2021.11.008. Epub 2021 Dec 13.

Globally, the use of drugs from traditional pharmacopoeias is a major subject. The confidence of the populations in these drugs is linked to their presumption of safety and also to the fact that geographically and financially they are more...

Two species? - Limits of the species concepts in the pygmy grasshoppers of the .

ZooKeys

Moser V, Baur H, Lehmann AW, Lehmann GUC.
PMID: 34163294
Zookeys. 2021 Jun 11;1043:33-59. doi: 10.3897/zookeys.1043.68316. eCollection 2021.

Today, integrative taxonomy is often considered the gold standard when it comes to species recognition and delimitation. Using the

Characterization of Weak Protein Domain Structure by Spin-Label Distance Distributions.

Frontiers in molecular biosciences

Ritsch I, Esteban-Hofer L, Lehmann E, Emmanouilidis L, Yulikov M, Allain FH, Jeschke G.
PMID: 33912586
Front Mol Biosci. 2021 Apr 12;8:636599. doi: 10.3389/fmolb.2021.636599. eCollection 2021.

Function of intrinsically disordered proteins may depend on deviation of their conformational ensemble from that of a random coil. Such deviation may be hard to characterize and quantify, if it is weak. We explored the potential of distance distributions...

A scoping review of knowledge authoring tools used for developing computerized clinical decision support systems.

JAMIA open

Nair SS, Li C, Doijad R, Nagy P, Lehmann H, Kharrazi H.
PMID: 34927003
JAMIA Open. 2021 Dec 16;4(4):ooab106. doi: 10.1093/jamiaopen/ooab106. eCollection 2021 Oct.

OBJECTIVE: Clinical Knowledge Authoring Tools (CKATs) are integral to the computerized Clinical Decision Support (CDS) development life cycle. CKATs enable authors to generate accurate, complete, and reliable digital knowledge artifacts in a relatively efficient and affordable manner. This scoping...

Development of a Mobile App for Ecological Momentary Assessment of Circadian Data: Design Considerations and Usability Testing.

JMIR formative research

Woolf TB, Goheer A, Holzhauer K, Martinez J, Coughlin JW, Martin L, Zhao D, Song S, Ahmad Y, Sokolinskyi K, Remayeva T, Clark JM, Bennett W, Lehmann H.
PMID: 34296999
JMIR Form Res. 2021 Jul 23;5(7):e26297. doi: 10.2196/26297.

BACKGROUND: Collecting data on daily habits across a population of individuals is challenging. Mobile-based circadian ecological momentary assessment (cEMA) is a powerful frame for observing the impact of daily living on long-term health.OBJECTIVE: In this paper, we (1) describe...

Whole Genome Interpretation for a Family of Five.

Frontiers in genetics

Corpas M, Megy K, Mistry V, Metastasio A, Lehmann E.
PMID: 33763108
Front Genet. 2021 Mar 08;12:535123. doi: 10.3389/fgene.2021.535123. eCollection 2021.

Although best practices have emerged on how to analyse and interpret personal genomes, the utility of whole genome screening remains underdeveloped. A large amount of information can be gathered from various types of analyses via whole genome sequencing including...

Synergies and distinctions between computational disciplines in biomedical research: perspective from the Clinical andTranslational Science Award programs.

Anderson N, Bernstam EV, Harris PA, Eichmann D, Hersh WR, Johnson SB, Chute CG, Nguyen H, Sim I, Nahm M, Weiner MG, Miller P, DiLaura RP, Overcash M, Lehmann HP, Athey BD, Scheuermann RH, Starren J, Smith JW, Barbour E, Silverstein JC, Krusch DA, Nagarajan R, Becich MJ.
UIID-AD: 2662
2009;84:964-70. doi: 10.1097/ACM.0b013e3181a8144d.

Clinical and translational research increasingly requires computation. Projects may involve multiple computationally oriented groups including information technology (IT) professionals, computer scientists, and biomedical informaticians. However, many biomedical researchers are not aware of the distinctions among these complementary groups, leading...

Showing 313 to 323 of 323 entries