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Showing 9973 to 9984 of 20856 entries
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Characteristics of Metastatic Mediastinal Lymph Nodes of Non-Small Cell Lung Cancer on Preoperative F-18 FDG PET/CT.

Nuclear medicine and molecular imaging

Lee AY, Choi SJ, Jung KP, Park JS, Lee SM, Bae SK.
PMID: 24900137
Nucl Med Mol Imaging. 2014 Mar;48(1):41-6. doi: 10.1007/s13139-013-0244-2. Epub 2013 Nov 06.

PURPOSE: The aim of this study was to evaluate the characteristics of PET and CT features of mediastinal metastatic lymph nodes on F-18 FDG PET/CT and to determine the diagnostic criteria in nodal staging of non-small cell lung cancer.METHODS:...

4-Methoxy-N-[2-(trifluoromethyl)biphenyl-4-ylcarbamoyl]nicotinamide: A Potent and Selective Agonist of S1P1.

ACS medicinal chemistry letters

Pennington LD, Sham KK, Pickrell AJ, Harrington PE, Frohn MJ, Lanman BA, Reed AB, Croghan MD, Lee MR, Xu H, McElvain M, Xu Y, Zhang X, Fiorino M, Horner M, Morrison HG, Arnett HA, Fotsch C, Wong M, Cee VJ.
PMID: 24900263
ACS Med Chem Lett. 2011 Jul 29;2(10):752-7. doi: 10.1021/ml2001399. eCollection 2011 Oct 13.

The sphingosine-1-phosphate-1 receptor (S1P1) and its endogenous ligand sphingosine-1-phosphate (S1P) cooperatively regulate lymphocyte trafficking from the lymphatic system. Herein, we disclose 4-methoxy-N-[2-(trifluoromethyl)biphenyl-4-ylcarbamoyl]nicotinamide (8), an uncommon example of a synthetic S1P1 agonist lacking a polar headgroup, which is shown to...

Influence of plasma conditions on the intensity ratio calibration curve during laser induced breakdown spectroscopy analysis.

Optics letters

Kim CK, In JH, Lee SH, Jeong S.
PMID: 24978745
Opt Lett. 2014 Jul 01;39(13):3818-21. doi: 10.1364/OL.39.003818.

Quantitative prediction of elemental concentration or concentration ratio of solid samples can be achieved by laser induced breakdown spectroscopy if a calibration curve that is little influenced by plasma conditions could be obtained. This work demonstrates that such a...

Synthesis and SAR of Thiazolylmethylphenyl Glucoside as Novel C-Aryl Glucoside SGLT2 Inhibitors.

ACS medicinal chemistry letters

Song KS, Lee SH, Kim MJ, Seo HJ, Lee J, Lee SH, Jung ME, Son EJ, Lee M, Kim J, Lee J.
PMID: 24900297
ACS Med Chem Lett. 2010 Dec 13;2(2):182-7. doi: 10.1021/ml100256c. eCollection 2011 Feb 10.

Novel C-aryl glucoside SGLT2 inhibitors containing the thiazole motif were designed and synthesized for biological evaluation. Among the compounds assayed, thiazole containing furanyl moiety 14v and thiophenyl moiety 14y demonstrated the best in vitro inhibitory activity against SGLT2 in...

What type of plastic do sea turtles in Korean waters mainly ingest? Quantity, shape, color, size, polymer composition, and original usage.

Environmental pollution (Barking, Essex : 1987)

Moon Y, Shim WJ, Han GM, Jeong J, Cho Y, Kim IH, Kim MS, Lee HR, Hong SH.
PMID: 35032602
Environ Pollut. 2022 Jan 12;118849. doi: 10.1016/j.envpol.2022.118849. Epub 2022 Jan 12.

Globally, sea turtles are at high risk of ingesting plastic. However, research on plastic ingestion by sea turtles in East Asia is scant, and no quantitative or qualitative investigation has been conducted in Korean waters. This study examined the...

Multiple Primary Malignancies in Patients with Gynecologic Cancer.

Journal of clinical medicine

Yang EJ, Lee JH, Lee AJ, Kim NR, Ouh YT, Kim MK, Shim SH, Lee SJ, Kim TJ, So KA.
PMID: 35011855
J Clin Med. 2021 Dec 26;11(1). doi: 10.3390/jcm11010115.

OBJECTIVE: To investigate the prevalence and oncologic outcomes of patients with multiple primary malignant tumors (MPMT) with gynecologic cancer.METHODS: This retrospective study included 1929 patients diagnosed with gynecologic cancer at a tertiary medical center between August 2005 and April...

Risk Factors for Orbital Implant Extrusion after Evisceration.

Journal of clinical medicine

Kim JM, Sung JY, Lim HB, Choi EJ, Lee SB.
PMID: 34362115
J Clin Med. 2021 Jul 28;10(15). doi: 10.3390/jcm10153329.

This study analyzed risk factors for extrusion of orbital implants after evisceration by comparing patients with and without implant extrusion.METHODS: We retrospectively reviewed the medical records of patients who underwent evisceration with primary implant placement by a single surgeon...

The Urinary Proteomic Profile Implicates Key Regulators for Urologic Chronic Pelvic Pain Syndrome (UCPPS): A MAPP Research Network Study.

Molecular & cellular proteomics : MCP

Froehlich JW, Wang HS, Logvinenko T, Kostel S, DiMartino S, van Bokhoven A, Moses MA, Lee RS.
PMID: 34774759
Mol Cell Proteomics. 2021 Nov 11;21(1):100176. doi: 10.1016/j.mcpro.2021.100176. Epub 2021 Nov 11.

Urologic chronic pelvic pain syndrome (UCPPS) is a condition of unknown etiology characterized by pelvic pain and urinary frequency and/or urgency. As the proximal fluid of this syndrome, urine is an ideal candidate sample matrix for an unbiased study...

Ribosomal Protein S6: A Potential Therapeutic Target against Cancer?.

International journal of molecular sciences

Yi YW, You KS, Park JS, Lee SG, Seong YS.
PMID: 35008473
Int J Mol Sci. 2021 Dec 21;23(1). doi: 10.3390/ijms23010048.

Ribosomal protein S6 (RPS6) is a component of the 40S small ribosomal subunit and participates in the control of mRNA translation. Additionally, phospho (p)-RPS6 has been recognized as a surrogate marker for the activated PI3K/AKT/mTORC1 pathway, which occurs in...

Moisture-induced autonomous surface potential oscillations for energy harvesting.

Nature communications

Long Y, He P, Shao Z, Li Z, Kim H, Yao AM, Peng Y, Xu R, Ahn CH, Lee SW, Zhong J, Lin L.
PMID: 34489424
Nat Commun. 2021 Sep 06;12(1):5287. doi: 10.1038/s41467-021-25554-y.

A variety of autonomous oscillations in nature such as heartbeats and some biochemical reactions have been widely studied and utilized for applications in the fields of bioscience and engineering. Here, we report a unique phenomenon of moisture-induced electrical potential...

Evaluation of persistence and healthcare utilization in patients treated with anti-seizure medications as add-on therapy: A nationwide cohort study in South Korea.

Epilepsy & behavior : E&B

Lee JW, Kim JA, Kim MY, Lee SK.
PMID: 34902660
Epilepsy Behav. 2021 Dec 10;126:108459. doi: 10.1016/j.yebeh.2021.108459. Epub 2021 Dec 10.

OBJECTIVE: To compare medication adherence and healthcare utilization among patients who were treated with anti-seizure medications (ASMs) as first add-on to monotherapy for epilepsy using the national health insurance claims data.METHODS: A retrospective observational cohort study was conducted using...

Optimization of dose selection using multiple surrogates of toxicity as a continuous variable in phase I cancer trial.

Contemporary clinical trials

Lee SY, Munafo A, Girard P, Goteti K.
PMID: 34954097
Contemp Clin Trials. 2021 Dec 22;113:106657. doi: 10.1016/j.cct.2021.106657. Epub 2021 Dec 22.

In phase I trials, it is the top priority of clinicians to effectively treat patients and minimize the chance of exposing them to subtherapeutic and overly toxic doses, while exploiting patient information. Motived by this practical consideration, we revive...

Showing 9973 to 9984 of 20856 entries