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Emergence of SGLT2 Inhibitors as Powerful Antioxidants in Human Diseases.

Antioxidants (Basel, Switzerland)

Tsai KF, Chen YL, Chiou TT, Chu TH, Li LC, Ng HY, Lee WC, Lee CT.
PMID: 34439414
Antioxidants (Basel). 2021 Jul 22;10(8). doi: 10.3390/antiox10081166.

Sodium-glucose cotransporter 2 (SGLT2) inhibitors are a new class of oral glucose-lowering agents. Apart from their glucose-lowering effects, large clinical trials assessing certain SGLT2 inhibitors have revealed cardiac and renal protective effects in non-diabetic patients. These excellent outcomes motivated...

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Tsai KF, Chen YL, Chiou TT, et al. Emergence of SGLT2 Inhibitors as Powerful Antioxidants in Human Diseases. Antioxidants (Basel). 2021;10(8)doi: 10.3390/antiox10081166.
Tsai, K. F., Chen, Y. L., Chiou, T. T., Chu, T. H., Li, L. C., Ng, H. Y., Lee, W. C., & Lee, C. T. (2021). Emergence of SGLT2 Inhibitors as Powerful Antioxidants in Human Diseases. Antioxidants (Basel, Switzerland), 10(8), . https://doi.org/10.3390/antiox10081166
Tsai, Kai-Fan, et al. "Emergence of SGLT2 Inhibitors as Powerful Antioxidants in Human Diseases." Antioxidants (Basel, Switzerland) vol. 10,8 (2021). doi: https://doi.org/10.3390/antiox10081166
Tsai KF, Chen YL, Chiou TT, Chu TH, Li LC, Ng HY, Lee WC, Lee CT. Emergence of SGLT2 Inhibitors as Powerful Antioxidants in Human Diseases. Antioxidants (Basel). 2021 Jul 22;10(8). doi: 10.3390/antiox10081166. PMID: 34439414; PMCID: PMC8388972.
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Peripheral vasoreactivity in acute ischemic stroke with hemiplegia.

Scientific reports

Wang SJ, Lee CH, Kang HG, Kim KW, Kim M, Jeong HJ, Shin BS.
PMID: 33879816
Sci Rep. 2021 Apr 20;11(1):8531. doi: 10.1038/s41598-021-88050-9.

The association between vasomotor tone of the peripheral arteries and cerebral hemisphere function has not been established. This study analyzed the peripheral vasoreactivity of patients with acute ischemic stroke and hemiplegia using a modified Raynaud scan, which is a...

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Wang SJ, Lee CH, Kang HG, et al. Peripheral vasoreactivity in acute ischemic stroke with hemiplegia. Sci Rep. 2021;11(1):8531doi: 10.1038/s41598-021-88050-9.
Wang, S. J., Lee, C. H., Kang, H. G., Kim, K. W., Kim, M., Jeong, H. J., & Shin, B. S. (2021). Peripheral vasoreactivity in acute ischemic stroke with hemiplegia. Scientific reports, 11(1), 8531. https://doi.org/10.1038/s41598-021-88050-9
Wang, Su Jeong, et al. "Peripheral vasoreactivity in acute ischemic stroke with hemiplegia." Scientific reports vol. 11,1 (2021): 8531. doi: https://doi.org/10.1038/s41598-021-88050-9
Wang SJ, Lee CH, Kang HG, Kim KW, Kim M, Jeong HJ, Shin BS. Peripheral vasoreactivity in acute ischemic stroke with hemiplegia. Sci Rep. 2021 Apr 20;11(1):8531. doi: 10.1038/s41598-021-88050-9. PMID: 33879816; PMCID: PMC8058338.
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Cytokine ranking via mutual information algorithm correlates cytokine profiles with presenting disease severity in patients with COVID-19.

medRxiv : the preprint server for health sciences

Huntington KE, Louie AD, Lee CG, Elias JA, Ross EA, El-Deiry WS.
PMID: 33269361
medRxiv. 2020 Nov 27; doi: 10.1101/2020.11.24.20235721.

Although the range of immune responses to COVID-19 infection is variable, cytokine storm is observed in many affected individuals. To further understand the disease pathogenesis and, consequently, to develop an additional tool for clinicians to evaluate patients for presumptive...

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Huntington KE, Louie AD, Lee CG, et al. Cytokine ranking via mutual information algorithm correlates cytokine profiles with presenting disease severity in patients with COVID-19. medRxiv. 2020;doi: 10.1101/2020.11.24.20235721.
Huntington, K. E., Louie, A. D., Lee, C. G., Elias, J. A., Ross, E. A., & El-Deiry, W. S. (2020). Cytokine ranking via mutual information algorithm correlates cytokine profiles with presenting disease severity in patients with COVID-19. medRxiv : the preprint server for health sciences, . https://doi.org/10.1101/2020.11.24.20235721
Huntington, Kelsey E, et al. "Cytokine ranking via mutual information algorithm correlates cytokine profiles with presenting disease severity in patients with COVID-19." medRxiv : the preprint server for health sciences vol. (2020). doi: https://doi.org/10.1101/2020.11.24.20235721
Huntington KE, Louie AD, Lee CG, Elias JA, Ross EA, El-Deiry WS. Cytokine ranking via mutual information algorithm correlates cytokine profiles with presenting disease severity in patients with COVID-19. medRxiv. 2020 Nov 27; doi: 10.1101/2020.11.24.20235721. PMID: 33269361; PMCID: PMC7709181.
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Expanded IL-22.

Immune network

Min HK, Moon J, Lee SY, Lee AR, Lee CR, Lee J, Kwok SK, Cho ML, Park SH.
PMID: 35036030
Immune Netw. 2021 Nov 18;21(6):e43. doi: 10.4110/in.2021.21.e43. eCollection 2021 Dec.

Group 3 innate lymphoid cells (ILC3), which express IL-22 and IL-17A, has been introduced as one of pathologic cells in axial spondyloarthritis (axSpA). Dyslipidaemia should be managed in axSpA patients to reduce cardiovascular disease, and dyslipidaemia promotes inflammation. This...

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Min HK, Moon J, Lee SY, et al. Expanded IL-22. Immune Netw. 2021;21(6):e43doi: 10.4110/in.2021.21.e43.
Min, H. K., Moon, J., Lee, S. Y., Lee, A. R., Lee, C. R., Lee, J., Kwok, S. K., Cho, M. L., & Park, S. H. (2021). Expanded IL-22. Immune network, 21(6), e43. https://doi.org/10.4110/in.2021.21.e43
Min, Hong Ki, et al. "Expanded IL-22." Immune network vol. 21,6 (2021): e43. doi: https://doi.org/10.4110/in.2021.21.e43
Min HK, Moon J, Lee SY, Lee AR, Lee CR, Lee J, Kwok SK, Cho ML, Park SH. Expanded IL-22. Immune Netw. 2021 Nov 18;21(6):e43. doi: 10.4110/in.2021.21.e43. eCollection 2021 Dec. PMID: 35036030; PMCID: PMC8733192.
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Serum levels of 4-hydroxynonenal adducts and responding autoantibodies correlate with the pathogenesis from hyperglycemia to Alzheimer's disease.

Clinical biochemistry

Renuka Sanotra M, Huang WC, Silver S, Lin CY, Chang TC, Doan Phuong Quy N, Lee CK, Kao SH, Chang-Cheng Shieh J, Lin YF.
PMID: 34933007
Clin Biochem. 2021 Dec 18; doi: 10.1016/j.clinbiochem.2021.12.005. Epub 2021 Dec 18.

OBJECTIVE: Hyperglycemia leads to lipid peroxidation, producing 4-hydroxynonenal (HNE) adducts which correlate with the production of amyloid-beta (Aβ), one of the hallmarks of Alzheimer's disease (AD). This study is to investigate the interactions of Aβ, HNE adducts and responding...

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Renuka Sanotra M, Huang WC, Silver S, et al. Serum levels of 4-hydroxynonenal adducts and responding autoantibodies correlate with the pathogenesis from hyperglycemia to Alzheimer's disease. Clin Biochem. 2021;doi: 10.1016/j.clinbiochem.2021.12.005.
Renuka Sanotra, M., Huang, W. C., Silver, S., Lin, C. Y., Chang, T. C., Doan Phuong Quy, N., Lee, C. K., Kao, S. H., Chang-Cheng Shieh, J., & Lin, Y. F. (2021). Serum levels of 4-hydroxynonenal adducts and responding autoantibodies correlate with the pathogenesis from hyperglycemia to Alzheimer's disease. Clinical biochemistry, . https://doi.org/10.1016/j.clinbiochem.2021.12.005
Renuka Sanotra, Monika, et al. "Serum levels of 4-hydroxynonenal adducts and responding autoantibodies correlate with the pathogenesis from hyperglycemia to Alzheimer's disease." Clinical biochemistry vol. (2021). doi: https://doi.org/10.1016/j.clinbiochem.2021.12.005
Renuka Sanotra M, Huang WC, Silver S, Lin CY, Chang TC, Doan Phuong Quy N, Lee CK, Kao SH, Chang-Cheng Shieh J, Lin YF. Serum levels of 4-hydroxynonenal adducts and responding autoantibodies correlate with the pathogenesis from hyperglycemia to Alzheimer's disease. Clin Biochem. 2021 Dec 18; doi: 10.1016/j.clinbiochem.2021.12.005. Epub 2021 Dec 18. PMID: 34933007.
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Lung Cancer Screening Considerations During Respiratory Infection Outbreaks, Epidemics or Pandemics: An IASLC Early Detection and Screening Committee Report.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

Huber RM, Cavic M, Kerpel-Fronius A, Viola L, Field J, Jiang L, Kazerooni EA, Koegelenberg CF, Mohan A, Sales Dos Santos R, Ventura L, Wynes M, Yang D, Zulueta J, Lee CT, Tammemagi CM, Henschke CI, Lam S.
PMID: 34864164
J Thorac Oncol. 2021 Dec 02; doi: 10.1016/j.jtho.2021.11.008. Epub 2021 Dec 02.

After the results of two large, randomized trials, the global implementation of lung cancer screening is of outmost importance. However, COVID-19 infections occurring at heightened levels during the current global pandemic, and also other respiratory infections, can influence scan...

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Huber RM, Cavic M, Kerpel-Fronius A, et al. Lung Cancer Screening Considerations During Respiratory Infection Outbreaks, Epidemics or Pandemics: An IASLC Early Detection and Screening Committee Report. J Thorac Oncol. 2021;doi: 10.1016/j.jtho.2021.11.008.
Huber, R. M., Cavic, M., Kerpel-Fronius, A., Viola, L., Field, J., Jiang, L., Kazerooni, E. A., Koegelenberg, C. F., Mohan, A., Sales Dos Santos, R., Ventura, L., Wynes, M., Yang, D., Zulueta, J., Lee, C. T., Tammemagi, C. M., Henschke, C. I., Lam, S. (2021). Lung Cancer Screening Considerations During Respiratory Infection Outbreaks, Epidemics or Pandemics: An IASLC Early Detection and Screening Committee Report. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, . https://doi.org/10.1016/j.jtho.2021.11.008
Huber, Rudolf M, et al. "Lung Cancer Screening Considerations During Respiratory Infection Outbreaks, Epidemics or Pandemics: An IASLC Early Detection and Screening Committee Report." Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer vol. (2021). doi: https://doi.org/10.1016/j.jtho.2021.11.008
Huber RM, Cavic M, Kerpel-Fronius A, Viola L, Field J, Jiang L, Kazerooni EA, Koegelenberg CF, Mohan A, Sales Dos Santos R, Ventura L, Wynes M, Yang D, Zulueta J, Lee CT, Tammemagi CM, Henschke CI, Lam S. Lung Cancer Screening Considerations During Respiratory Infection Outbreaks, Epidemics or Pandemics: An IASLC Early Detection and Screening Committee Report. J Thorac Oncol. 2021 Dec 02; doi: 10.1016/j.jtho.2021.11.008. Epub 2021 Dec 02. PMID: 34864164; PMCID: PMC8639478.
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Fasting Blood Glucose Variability and Unfavorable Trajectory Patterns Are Associated with the Risk of Colorectal Cancer.

Gut and liver

Jun H, Lee J, Lee HA, Kim SE, Shim KN, Jung HK, Jung SA, Moon CM.
PMID: 34593671
Gut Liver. 2021 Oct 01; doi: 10.5009/gnl210048. Epub 2021 Oct 01.

BACKGROUND/AIMS: The relationship between fasting blood glucose (FBG) variability and colorectal cancer (CRC) remains ill-defined. This study aimed to evaluate the association of FBG variability with CRC risk in the healthy population without overt diabetes.METHODS: In the data from...

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Jun H, Lee J, Lee HA, et al. Fasting Blood Glucose Variability and Unfavorable Trajectory Patterns Are Associated with the Risk of Colorectal Cancer. Gut Liver. 2021;doi: 10.5009/gnl210048.
Jun, H., Lee, J., Lee, H. A., Kim, S. E., Shim, K. N., Jung, H. K., Jung, S. A., & Moon, C. M. (2021). Fasting Blood Glucose Variability and Unfavorable Trajectory Patterns Are Associated with the Risk of Colorectal Cancer. Gut and liver, . https://doi.org/10.5009/gnl210048
Jun, Hyoju, et al. "Fasting Blood Glucose Variability and Unfavorable Trajectory Patterns Are Associated with the Risk of Colorectal Cancer." Gut and liver vol. (2021). doi: https://doi.org/10.5009/gnl210048
Jun H, Lee J, Lee HA, Kim SE, Shim KN, Jung HK, Jung SA, Moon CM. Fasting Blood Glucose Variability and Unfavorable Trajectory Patterns Are Associated with the Risk of Colorectal Cancer. Gut Liver. 2021 Oct 01; doi: 10.5009/gnl210048. Epub 2021 Oct 01. PMID: 34593671.
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A novel microsurgery clamp incorporating the cuff technique for ultrasmall vessel coaptation.

Journal of plastic, reconstructive & aesthetic surgery : JPRAS

Wang AYL, Shen HH, Lo WH, Yu WL, Liu YL, Lee CM, Loh CYY.
PMID: 34697004
J Plast Reconstr Aesthet Surg. 2021 Dec;74(12):3443-3476. doi: 10.1016/j.bjps.2021.09.006. Epub 2021 Oct 07.

No abstract available.

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Wang AYL, Shen HH, Lo WH, et al. A novel microsurgery clamp incorporating the cuff technique for ultrasmall vessel coaptation. J Plast Reconstr Aesthet Surg. 2021;74(12):3443-3476doi: 10.1016/j.bjps.2021.09.006.
Wang, A. Y. L., Shen, H. H., Lo, W. H., Yu, W. L., Liu, Y. L., Lee, C. M., & Loh, C. Y. Y. (2021). A novel microsurgery clamp incorporating the cuff technique for ultrasmall vessel coaptation. Journal of plastic, reconstructive & aesthetic surgery : JPRAS, 74(12), 3443-3476. https://doi.org/10.1016/j.bjps.2021.09.006
Wang, Aline Yen Ling, et al. "A novel microsurgery clamp incorporating the cuff technique for ultrasmall vessel coaptation." Journal of plastic, reconstructive & aesthetic surgery : JPRAS vol. 74,12 (2021): 3443-3476. doi: https://doi.org/10.1016/j.bjps.2021.09.006
Wang AYL, Shen HH, Lo WH, Yu WL, Liu YL, Lee CM, Loh CYY. A novel microsurgery clamp incorporating the cuff technique for ultrasmall vessel coaptation. J Plast Reconstr Aesthet Surg. 2021 Dec;74(12):3443-3476. doi: 10.1016/j.bjps.2021.09.006. Epub 2021 Oct 07. PMID: 34697004.
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A Perspective on Imiquimod Microneedles for Treating Warts.

Pharmaceutics

Chiu TM, Hsu PC, Khan MY, Lin CJ, Lee CH, Hsu TC, Chen MH, Hanagata N.
PMID: 33922157
Pharmaceutics. 2021 Apr 22;13(5). doi: 10.3390/pharmaceutics13050607.

Warts are a common skin problem and are caused by infection with a virus. Warts are currently mainly treated by therapies involving ablating tissue or interrupting cellular division. However, all these existing treatments are either invasive or cause skin...

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Chiu TM, Hsu PC, Khan MY, et al. A Perspective on Imiquimod Microneedles for Treating Warts. Pharmaceutics. 2021;13(5)doi: 10.3390/pharmaceutics13050607.
Chiu, T. M., Hsu, P. C., Khan, M. Y., Lin, C. J., Lee, C. H., Hsu, T. C., Chen, M. H., & Hanagata, N. (2021). A Perspective on Imiquimod Microneedles for Treating Warts. Pharmaceutics, 13(5), . https://doi.org/10.3390/pharmaceutics13050607
Chiu, Tsu-Man, et al. "A Perspective on Imiquimod Microneedles for Treating Warts." Pharmaceutics vol. 13,5 (2021). doi: https://doi.org/10.3390/pharmaceutics13050607
Chiu TM, Hsu PC, Khan MY, Lin CJ, Lee CH, Hsu TC, Chen MH, Hanagata N. A Perspective on Imiquimod Microneedles for Treating Warts. Pharmaceutics. 2021 Apr 22;13(5). doi: 10.3390/pharmaceutics13050607. PMID: 33922157; PMCID: PMC8146107.
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COVID Toes: Concurrent Lower Limb Arterial and Venous Thromboembolism in a Patient with COVID-19 Pneumonitis Presenting with Foot Ischaemia.

Vascular and endovascular surgery

Lee KA, McBride RS, Narlawar R, Myers R, Antoniou GA.
PMID: 34592855
Vasc Endovascular Surg. 2021 Sep 30;15385744211045600. doi: 10.1177/15385744211045600. Epub 2021 Sep 30.

We present a 74-year-old gentleman, who presented with foot ischaemia requiring bilateral amputation in the absence of radiological signs of occlusive peripheral arterial disease. He was found to have COVID-19 pneumonitis and concurrent arterial and venous thromboemboli despite no...

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Lee KA, McBride RS, Narlawar R, et al. COVID Toes: Concurrent Lower Limb Arterial and Venous Thromboembolism in a Patient with COVID-19 Pneumonitis Presenting with Foot Ischaemia. Vasc Endovascular Surg. 2021;15385744211045600doi: 10.1177/15385744211045600.
Lee, K. A., McBride, R. S., Narlawar, R., Myers, R., & Antoniou, G. A. (2021). COVID Toes: Concurrent Lower Limb Arterial and Venous Thromboembolism in a Patient with COVID-19 Pneumonitis Presenting with Foot Ischaemia. Vascular and endovascular surgery, 15385744211045600. https://doi.org/10.1177/15385744211045600
Lee, Kathryn A, et al. "COVID Toes: Concurrent Lower Limb Arterial and Venous Thromboembolism in a Patient with COVID-19 Pneumonitis Presenting with Foot Ischaemia." Vascular and endovascular surgery vol. (2021): 15385744211045600. doi: https://doi.org/10.1177/15385744211045600
Lee KA, McBride RS, Narlawar R, Myers R, Antoniou GA. COVID Toes: Concurrent Lower Limb Arterial and Venous Thromboembolism in a Patient with COVID-19 Pneumonitis Presenting with Foot Ischaemia. Vasc Endovascular Surg. 2021 Sep 30;15385744211045600. doi: 10.1177/15385744211045600. Epub 2021 Sep 30. PMID: 34592855.
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Pars Plana Vitrectomy for Endophthalmitis: Microbiologic Spectrum and Clinical Outcomes.

Ocular immunology and inflammation

Lee CS, Khan M, Patrie J, Bajwa A, Shildkrot YE.
PMID: 31906757
Ocul Immunol Inflamm. 2021 Jul 04;29(5):871-876. doi: 10.1080/09273948.2019.1698750. Epub 2020 Jan 06.

No abstract available.

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Lee CS, Khan M, Patrie J, et al. Pars Plana Vitrectomy for Endophthalmitis: Microbiologic Spectrum and Clinical Outcomes. Ocul Immunol Inflamm. 2020;29(5):871-876doi: 10.1080/09273948.2019.1698750.
Lee, C. S., Khan, M., Patrie, J., Bajwa, A., & Shildkrot, Y. E. (2021). Pars Plana Vitrectomy for Endophthalmitis: Microbiologic Spectrum and Clinical Outcomes. Ocular immunology and inflammation, 29(5), 871-876. https://doi.org/10.1080/09273948.2019.1698750
Lee, Chang Sup, et al. "Pars Plana Vitrectomy for Endophthalmitis: Microbiologic Spectrum and Clinical Outcomes." Ocular immunology and inflammation vol. 29,5 (2021): 871-876. doi: https://doi.org/10.1080/09273948.2019.1698750
Lee CS, Khan M, Patrie J, Bajwa A, Shildkrot YE. Pars Plana Vitrectomy for Endophthalmitis: Microbiologic Spectrum and Clinical Outcomes. Ocul Immunol Inflamm. 2021 Jul 04;29(5):871-876. doi: 10.1080/09273948.2019.1698750. Epub 2020 Jan 06. PMID: 31906757.
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Indirect Radiological Signs of Hollow Organ Perforation.

Journal of acute medicine

Lee CH.
PMID: 33928014
J Acute Med. 2021 Mar 01;11(1):28-31. doi: 10.6705/j.jacme.202103_11(1).0005.

Hollow organ perforation is a serious and common abdominal emergency. The diagnosis depends on history taking, physical examination, and radiological fi ndings. We reported a hollow organ perforation patient with only indirect radiological signs of the heterogenous enhanced lesion...

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Lee CH. Indirect Radiological Signs of Hollow Organ Perforation. J Acute Med. 2021;11(1):28-31doi: 10.6705/j.jacme.202103_11(1).0005.
Lee, C. H. (2021). Indirect Radiological Signs of Hollow Organ Perforation. Journal of acute medicine, 11(1), 28-31. https://doi.org/10.6705/j.jacme.202103_11(1).0005
Lee, Ching-Hsing. "Indirect Radiological Signs of Hollow Organ Perforation." Journal of acute medicine vol. 11,1 (2021): 28-31. doi: https://doi.org/10.6705/j.jacme.202103_11(1).0005
Lee CH. Indirect Radiological Signs of Hollow Organ Perforation. J Acute Med. 2021 Mar 01;11(1):28-31. doi: 10.6705/j.jacme.202103_11(1).0005. PMID: 33928014; PMCID: PMC8075965.
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Showing 9985 to 9996 of 10218 entries