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Inducible expression quantitative trait locus analysis of the MUC5AC gene in asthma in urban populations of children.

The Journal of allergy and clinical immunology

Altman MC, Flynn K, Rosasco MG, Dapas M, Kattan M, Lovinsky-Desir S, O'Connor GT, Gill MA, Gruchalla RS, Liu AH, Pongracic JA, Khurana Hershey GK, Zoratti EM, Teach SJ, Rastrogi D, Wood RA, Bacharier LB, LeBeau P, Gergen PJ, Togias A, Busse WW, Presnell S, Gern JE, Ober C, Jackson DJ.
PMID: 34019912
J Allergy Clin Immunol. 2021 Dec;148(6):1505-1514. doi: 10.1016/j.jaci.2021.04.035. Epub 2021 May 18.

BACKGROUND: Mucus plugging can worsen asthma control, lead to reduced lung function and fatal exacerbations. MUC5AC is the secretory mucin implicated in mucus plugging, and MUC5AC gene expression has been associated with development of airway obstruction and asthma exacerbations...

Showing 217 to 217 of 217 entries