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Investigating the Interaction between Negative Strand RNA Viruses and Their Hosts for Enhanced Vaccine Development and Production.

Vaccines

Mara K, Dai M, Brice AM, Alexander MR, Tribolet L, Layton DS, Bean AGD.
PMID: 33477334
Vaccines (Basel). 2021 Jan 17;9(1). doi: 10.3390/vaccines9010059.

The current pandemic has highlighted the ever-increasing risk of human to human spread of zoonotic pathogens. A number of medically-relevant zoonotic pathogens are negative-strand RNA viruses (NSVs). NSVs are derived from different virus families. Examples like Ebola are known...

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Mara K, Dai M, Brice AM, et al. Investigating the Interaction between Negative Strand RNA Viruses and Their Hosts for Enhanced Vaccine Development and Production. Vaccines (Basel). 2021;9(1)doi: 10.3390/vaccines9010059.
Mara, K., Dai, M., Brice, A. M., Alexander, M. R., Tribolet, L., Layton, D. S., & Bean, A. G. D. (2021). Investigating the Interaction between Negative Strand RNA Viruses and Their Hosts for Enhanced Vaccine Development and Production. Vaccines, 9(1), . https://doi.org/10.3390/vaccines9010059
Mara, Kostlend, et al. "Investigating the Interaction between Negative Strand RNA Viruses and Their Hosts for Enhanced Vaccine Development and Production." Vaccines vol. 9,1 (2021). doi: https://doi.org/10.3390/vaccines9010059
Mara K, Dai M, Brice AM, Alexander MR, Tribolet L, Layton DS, Bean AGD. Investigating the Interaction between Negative Strand RNA Viruses and Their Hosts for Enhanced Vaccine Development and Production. Vaccines (Basel). 2021 Jan 17;9(1). doi: 10.3390/vaccines9010059. PMID: 33477334; PMCID: PMC7830660.
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Prospective and detailed behavioral phenotyping in DDX3X syndrome.

Molecular autism

Tang L, Levy T, Guillory S, Halpern D, Zweifach J, Giserman-Kiss I, Foss-Feig JH, Frank Y, Lozano R, Belani P, Layton C, Lerman B, Frowner E, Breen MS, De Rubeis S, Kostic A, Kolevzon A, Buxbaum JD, Siper PM, Grice DE.
PMID: 33993884
Mol Autism. 2021 May 16;12(1):36. doi: 10.1186/s13229-021-00431-z.

BACKGROUND: DDX3X syndrome is a recently identified genetic disorder that accounts for 1-3% of cases of unexplained developmental delay and/or intellectual disability (ID) in females, and is associated with motor and language delays, and autism spectrum disorder (ASD). To...

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Tang L, Levy T, Guillory S, et al. Prospective and detailed behavioral phenotyping in DDX3X syndrome. Mol Autism. 2021;12(1):36doi: 10.1186/s13229-021-00431-z.
Tang, L., Levy, T., Guillory, S., Halpern, D., Zweifach, J., Giserman-Kiss, I., Foss-Feig, J. H., Frank, Y., Lozano, R., Belani, P., Layton, C., Lerman, B., Frowner, E., Breen, M. S., De Rubeis, S., Kostic, A., Kolevzon, A., Buxbaum, J. D., Siper, P. M., & Grice, D. E. (2021). Prospective and detailed behavioral phenotyping in DDX3X syndrome. Molecular autism, 12(1), 36. https://doi.org/10.1186/s13229-021-00431-z
Tang, Lara, et al. "Prospective and detailed behavioral phenotyping in DDX3X syndrome." Molecular autism vol. 12,1 (2021): 36. doi: https://doi.org/10.1186/s13229-021-00431-z
Tang L, Levy T, Guillory S, Halpern D, Zweifach J, Giserman-Kiss I, Foss-Feig JH, Frank Y, Lozano R, Belani P, Layton C, Lerman B, Frowner E, Breen MS, De Rubeis S, Kostic A, Kolevzon A, Buxbaum JD, Siper PM, Grice DE. Prospective and detailed behavioral phenotyping in DDX3X syndrome. Mol Autism. 2021 May 16;12(1):36. doi: 10.1186/s13229-021-00431-z. PMID: 33993884; PMCID: PMC8127248.
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Estimating the number of undetected COVID-19 cases among travellers from mainland China.

Wellcome open research

Bhatia S, Imai N, Cuomo-Dannenburg G, Baguelin M, Boonyasiri A, Cori A, Cucunubá Z, Dorigatti I, FitzJohn R, Fu H, Gaythorpe K, Ghani A, Hamlet A, Hinsley W, Laydon D, Nedjati-Gilani G, Okell L, Riley S, Thompson H, van Elsland S, Volz E, Wang H, Wang Y, Whittaker C, Xi X, Donnelly CA, Ferguson NM.
PMID: 34632083
Wellcome Open Res. 2020 Jun 15;5:143. doi: 10.12688/wellcomeopenres.15805.1. eCollection 2020.

No abstract available.

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Bhatia S, Imai N, Cuomo-Dannenburg G, et al. Estimating the number of undetected COVID-19 cases among travellers from mainland China. Wellcome Open Res. 2020;5:143doi: 10.12688/wellcomeopenres.15805.1.
Bhatia, S., Imai, N., Cuomo-Dannenburg, G., Baguelin, M., Boonyasiri, A., Cori, A., Cucunubá, Z., Dorigatti, I., FitzJohn, R., Fu, H., Gaythorpe, K., Ghani, A., Hamlet, A., Hinsley, W., Laydon, D., Nedjati-Gilani, G., Okell, L., Riley, S., Thompson, H., van Elsland, S., Volz, E., Wang, H., Wang, Y., Whittaker, C., Xi, X., Donnelly, C. A., & Ferguson, N. M. (2020). Estimating the number of undetected COVID-19 cases among travellers from mainland China. Wellcome open research, 5143. https://doi.org/10.12688/wellcomeopenres.15805.1
Bhatia, Sangeeta, et al. "Estimating the number of undetected COVID-19 cases among travellers from mainland China." Wellcome open research vol. 5 (2020): 143. doi: https://doi.org/10.12688/wellcomeopenres.15805.1
Bhatia S, Imai N, Cuomo-Dannenburg G, Baguelin M, Boonyasiri A, Cori A, Cucunubá Z, Dorigatti I, FitzJohn R, Fu H, Gaythorpe K, Ghani A, Hamlet A, Hinsley W, Laydon D, Nedjati-Gilani G, Okell L, Riley S, Thompson H, van Elsland S, Volz E, Wang H, Wang Y, Whittaker C, Xi X, Donnelly CA, Ferguson NM. Estimating the number of undetected COVID-19 cases among travellers from mainland China. Wellcome Open Res. 2020 Jun 15;5:143. doi: 10.12688/wellcomeopenres.15805.1. eCollection 2020. PMID: 34632083; PMCID: PMC8477353.
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Antimicrobial stewardship in Australia: the role of qualitative research in programme development.

JAC-antimicrobial resistance

Thursky KA, Hardefeldt LY, Rajkhowa A, Ierano C, Bishop J, Hawes L, Biezen R, Saha SK, Dowson L, Bailey KE, Scarborough R, Little SB, Gotterson F, Hur B, Khanina A, Urbancic K, Crabb HK, Richards S, Sri A, James R, Kong DCM, Marshall C, Mazza D, Peel T, Stuart RL, Manski-Nankervis JA, Friedman ND, Bennett N, Schulz T, Billman-Jacobe H, Buono E, Worth L, Bull A, Richards M, Ayton D, Gilkerson JR, Browning GF, Buising KL.
PMID: 34806005
JAC Antimicrob Resist. 2021 Nov 18;3(4):dlab166. doi: 10.1093/jacamr/dlab166. eCollection 2021 Dec.

Antimicrobial stewardship (AMS) in Australia is supported by a number of factors, including enabling national policies, sectoral clinical governance frameworks and surveillance programmes, clinician-led educational initiatives and health services research. A One Health research programme undertaken by the National...

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Thursky KA, Hardefeldt LY, Rajkhowa A, et al. Antimicrobial stewardship in Australia: the role of qualitative research in programme development. JAC Antimicrob Resist. 2021;3(4):dlab166doi: 10.1093/jacamr/dlab166.
Thursky, K. A., Hardefeldt, L. Y., Rajkhowa, A., Ierano, C., Bishop, J., Hawes, L., Biezen, R., Saha, S. K., Dowson, L., Bailey, K. E., Scarborough, R., Little, S. B., Gotterson, F., Hur, B., Khanina, A., Urbancic, K., Crabb, H. K., Richards, S., Sri, A., James, R., Kong, D. C. M., Marshall, C., Mazza, D., Peel, T., Stuart, R. L., Manski-Nankervis, J. A., Friedman, N. D., Bennett, N., Schulz, T., Billman-Jacobe, H., Buono, E., Worth, L., Bull, A., Richards, M., Ayton, D., Gilkerson, J. R., Browning, G. F., Buising, K. L. (2021). Antimicrobial stewardship in Australia: the role of qualitative research in programme development. JAC-antimicrobial resistance, 3(4), dlab166. https://doi.org/10.1093/jacamr/dlab166
Thursky, Karin A, et al. "Antimicrobial stewardship in Australia: the role of qualitative research in programme development." JAC-antimicrobial resistance vol. 3,4 (2021): dlab166. doi: https://doi.org/10.1093/jacamr/dlab166
Thursky KA, Hardefeldt LY, Rajkhowa A, Ierano C, Bishop J, Hawes L, Biezen R, Saha SK, Dowson L, Bailey KE, Scarborough R, Little SB, Gotterson F, Hur B, Khanina A, Urbancic K, Crabb HK, Richards S, Sri A, James R, Kong DCM, Marshall C, Mazza D, Peel T, Stuart RL, Manski-Nankervis JA, Friedman ND, Bennett N, Schulz T, Billman-Jacobe H, Buono E, Worth L, Bull A, Richards M, Ayton D, Gilkerson JR, Browning GF, Buising KL. Antimicrobial stewardship in Australia: the role of qualitative research in programme development. JAC Antimicrob Resist. 2021 Nov 18;3(4):dlab166. doi: 10.1093/jacamr/dlab166. eCollection 2021 Dec. PMID: 34806005; PMCID: PMC8600289.
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Sensory Reactivity Phenotype in Phelan-McDermid Syndrome Is Distinct from Idiopathic ASD.

Genes

Tavassoli T, Layton C, Levy T, Rowe M, George-Jones J, Zweifach J, Lurie S, Buxbaum JD, Kolevzon A, Siper PM.
PMID: 34206779
Genes (Basel). 2021 Jun 26;12(7). doi: 10.3390/genes12070977.

Phelan-McDermid syndrome (PMS) is one of the most common genetic forms of autism spectrum disorder (ASD). While sensory reactivity symptoms are widely reported in idiopathic ASD (iASD), few studies have examined sensory symptoms in PMS. The current study delineates...

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Tavassoli T, Layton C, Levy T, et al. Sensory Reactivity Phenotype in Phelan-McDermid Syndrome Is Distinct from Idiopathic ASD. Genes (Basel). 2021;12(7)doi: 10.3390/genes12070977.
Tavassoli, T., Layton, C., Levy, T., Rowe, M., George-Jones, J., Zweifach, J., Lurie, S., Buxbaum, J. D., Kolevzon, A., & Siper, P. M. (2021). Sensory Reactivity Phenotype in Phelan-McDermid Syndrome Is Distinct from Idiopathic ASD. Genes, 12(7), . https://doi.org/10.3390/genes12070977
Tavassoli, Teresa, et al. "Sensory Reactivity Phenotype in Phelan-McDermid Syndrome Is Distinct from Idiopathic ASD." Genes vol. 12,7 (2021). doi: https://doi.org/10.3390/genes12070977
Tavassoli T, Layton C, Levy T, Rowe M, George-Jones J, Zweifach J, Lurie S, Buxbaum JD, Kolevzon A, Siper PM. Sensory Reactivity Phenotype in Phelan-McDermid Syndrome Is Distinct from Idiopathic ASD. Genes (Basel). 2021 Jun 26;12(7). doi: 10.3390/genes12070977. PMID: 34206779; PMCID: PMC8306746.
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It doesn't stop at validation: patient reported outcome measures require ongoing and iterative development.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Parker C, Wei A, Liew D, Zomer E, Ayton D.
PMID: 34529139
Support Care Cancer. 2021 Sep 16; doi: 10.1007/s00520-021-06553-7. Epub 2021 Sep 16.

Patient reported outcomes (PROs) are a pillar of modern-day patient-centered care and clinical trials. PROs complement clinical information with the patient's own report about their experiences of health, without influence or interpretation by other people. However, choosing an appropriate...

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Parker C, Wei A, Liew D, et al. It doesn't stop at validation: patient reported outcome measures require ongoing and iterative development. Support Care Cancer. 2021;doi: 10.1007/s00520-021-06553-7.
Parker, C., Wei, A., Liew, D., Zomer, E., & Ayton, D. (2021). It doesn't stop at validation: patient reported outcome measures require ongoing and iterative development. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, . https://doi.org/10.1007/s00520-021-06553-7
Parker, Catriona, et al. "It doesn't stop at validation: patient reported outcome measures require ongoing and iterative development." Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer vol. (2021). doi: https://doi.org/10.1007/s00520-021-06553-7
Parker C, Wei A, Liew D, Zomer E, Ayton D. It doesn't stop at validation: patient reported outcome measures require ongoing and iterative development. Support Care Cancer. 2021 Sep 16; doi: 10.1007/s00520-021-06553-7. Epub 2021 Sep 16. PMID: 34529139.
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Order-disorder transitions of cytoplasmic N-termini in the mechanisms of P-type ATPases.

Faraday discussions

Hossain KR, Clayton D, Goodchild SC, Rodger A, Payne RJ, Cornelius F, Clarke RJ.
PMID: 34549220
Faraday Discuss. 2021 Dec 24;232:172-187. doi: 10.1039/d0fd00040j.

Membrane protein structure and function are modulated

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Hossain KR, Clayton D, Goodchild SC, et al. Order-disorder transitions of cytoplasmic N-termini in the mechanisms of P-type ATPases. Faraday Discuss. 2021;232:172-187doi: 10.1039/d0fd00040j.
Hossain, K. R., Clayton, D., Goodchild, S. C., Rodger, A., Payne, R. J., Cornelius, F., & Clarke, R. J. (2021). Order-disorder transitions of cytoplasmic N-termini in the mechanisms of P-type ATPases. Faraday discussions, 232172-187. https://doi.org/10.1039/d0fd00040j
Hossain, Khondker R, et al. "Order-disorder transitions of cytoplasmic N-termini in the mechanisms of P-type ATPases." Faraday discussions vol. 232 (2021): 172-187. doi: https://doi.org/10.1039/d0fd00040j
Hossain KR, Clayton D, Goodchild SC, Rodger A, Payne RJ, Cornelius F, Clarke RJ. Order-disorder transitions of cytoplasmic N-termini in the mechanisms of P-type ATPases. Faraday Discuss. 2021 Dec 24;232:172-187. doi: 10.1039/d0fd00040j. PMID: 34549220.
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A randomized controlled trial of intranasal oxytocin in Phelan-McDermid syndrome.

Molecular autism

Fastman J, Foss-Feig J, Frank Y, Halpern D, Harony-Nicolas H, Layton C, Sandin S, Siper P, Tang L, Trelles P, Zweifach J, Buxbaum JD, Kolevzon A.
PMID: 34593045
Mol Autism. 2021 Sep 30;12(1):62. doi: 10.1186/s13229-021-00459-1.

BACKGROUND: Phelan-McDermid syndrome (PMS) is a rare neurodevelopmental disorder caused by haploinsufficiency of the SHANK3 gene and characterized by global developmental delays, deficits in speech and motor function, and autism spectrum disorder (ASD). Monogenic causes of ASD such as...

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Fastman J, Foss-Feig J, Frank Y, et al. A randomized controlled trial of intranasal oxytocin in Phelan-McDermid syndrome. Mol Autism. 2021;12(1):62doi: 10.1186/s13229-021-00459-1.
Fastman, J., Foss-Feig, J., Frank, Y., Halpern, D., Harony-Nicolas, H., Layton, C., Sandin, S., Siper, P., Tang, L., Trelles, P., Zweifach, J., Buxbaum, J. D., & Kolevzon, A. (2021). A randomized controlled trial of intranasal oxytocin in Phelan-McDermid syndrome. Molecular autism, 12(1), 62. https://doi.org/10.1186/s13229-021-00459-1
Fastman, J, et al. "A randomized controlled trial of intranasal oxytocin in Phelan-McDermid syndrome." Molecular autism vol. 12,1 (2021): 62. doi: https://doi.org/10.1186/s13229-021-00459-1
Fastman J, Foss-Feig J, Frank Y, Halpern D, Harony-Nicolas H, Layton C, Sandin S, Siper P, Tang L, Trelles P, Zweifach J, Buxbaum JD, Kolevzon A. A randomized controlled trial of intranasal oxytocin in Phelan-McDermid syndrome. Mol Autism. 2021 Sep 30;12(1):62. doi: 10.1186/s13229-021-00459-1. PMID: 34593045; PMCID: PMC8482590.
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Life-threatening skin conditions presenting to critical care.

BJA education

Bromley M, Marsh S, Layton A, Connor DJ.
PMID: 34567792
BJA Educ. 2021 Oct;21(10):376-383. doi: 10.1016/j.bjae.2021.05.007. Epub 2021 Jul 23.

No abstract available.

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Bromley M, Marsh S, Layton A, et al. Life-threatening skin conditions presenting to critical care. BJA Educ. 2021;21(10):376-383doi: 10.1016/j.bjae.2021.05.007.
Bromley, M., Marsh, S., Layton, A., & Connor, D. J. (2021). Life-threatening skin conditions presenting to critical care. BJA education, 21(10), 376-383. https://doi.org/10.1016/j.bjae.2021.05.007
Bromley, M, et al. "Life-threatening skin conditions presenting to critical care." BJA education vol. 21,10 (2021): 376-383. doi: https://doi.org/10.1016/j.bjae.2021.05.007
Bromley M, Marsh S, Layton A, Connor DJ. Life-threatening skin conditions presenting to critical care. BJA Educ. 2021 Oct;21(10):376-383. doi: 10.1016/j.bjae.2021.05.007. Epub 2021 Jul 23. PMID: 34567792; PMCID: PMC8446252.
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Technology for Healthy Aging and Wellbeing: Co-producing Solutions.

Frontiers in psychology

Astell AJ, Andrews JA, Bennion MR, Clayton D.
PMID: 34925149
Front Psychol. 2021 Dec 02;12:745947. doi: 10.3389/fpsyg.2021.745947. eCollection 2021.

Methods to facilitate co-production in mental health are important for engaging end users. As part of the Technology for Healthy Aging and Wellbeing (THAW) initiative we organized two interactive co-production workshops, to bring together older adults, health and social...

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Astell AJ, Andrews JA, Bennion MR, et al. Technology for Healthy Aging and Wellbeing: Co-producing Solutions. Front Psychol. 2021;12:745947doi: 10.3389/fpsyg.2021.745947.
Astell, A. J., Andrews, J. A., Bennion, M. R., & Clayton, D. (2021). Technology for Healthy Aging and Wellbeing: Co-producing Solutions. Frontiers in psychology, 12745947. https://doi.org/10.3389/fpsyg.2021.745947
Astell, Arlene J, et al. "Technology for Healthy Aging and Wellbeing: Co-producing Solutions." Frontiers in psychology vol. 12 (2021): 745947. doi: https://doi.org/10.3389/fpsyg.2021.745947
Astell AJ, Andrews JA, Bennion MR, Clayton D. Technology for Healthy Aging and Wellbeing: Co-producing Solutions. Front Psychol. 2021 Dec 02;12:745947. doi: 10.3389/fpsyg.2021.745947. eCollection 2021. PMID: 34925149; PMCID: PMC8674183.
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Type I Hypersensitivity in Ferrets Following Exposure to SARS-CoV-2 Inoculum: Lessons Learned.

ILAR journal

Layton D, Burkett K, Marsh GA, Singanallur NB, Barr J, Layton R, Riddell SJ, Brown S, Trinidad L, Au GG, McAuley AJ, Lowther S, Watson J, Vasan SS.
PMID: 34157067
ILAR J. 2021 Jun 23; doi: 10.1093/ilar/ilab019. Epub 2021 Jun 23.

This case report discusses Type I hypersensitivity in ferrets following exposure to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) inoculum, observed during a study investigating the efficacy of candidate COVID-19 vaccines. Following a comprehensive internal root-cause investigation, it was...

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Layton D, Burkett K, Marsh GA, et al. Type I Hypersensitivity in Ferrets Following Exposure to SARS-CoV-2 Inoculum: Lessons Learned. ILAR J. 2021;doi: 10.1093/ilar/ilab019.
Layton, D., Burkett, K., Marsh, G. A., Singanallur, N. B., Barr, J., Layton, R., Riddell, S. J., Brown, S., Trinidad, L., Au, G. G., McAuley, A. J., Lowther, S., Watson, J., & Vasan, S. S. (2021). Type I Hypersensitivity in Ferrets Following Exposure to SARS-CoV-2 Inoculum: Lessons Learned. ILAR journal, . https://doi.org/10.1093/ilar/ilab019
Layton, Daniel, et al. "Type I Hypersensitivity in Ferrets Following Exposure to SARS-CoV-2 Inoculum: Lessons Learned." ILAR journal vol. (2021). doi: https://doi.org/10.1093/ilar/ilab019
Layton D, Burkett K, Marsh GA, Singanallur NB, Barr J, Layton R, Riddell SJ, Brown S, Trinidad L, Au GG, McAuley AJ, Lowther S, Watson J, Vasan SS. Type I Hypersensitivity in Ferrets Following Exposure to SARS-CoV-2 Inoculum: Lessons Learned. ILAR J. 2021 Jun 23; doi: 10.1093/ilar/ilab019. Epub 2021 Jun 23. PMID: 34157067; PMCID: PMC8344777.
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Social networks and subjective wellbeing of adults in a Housing First program.

Journal of community psychology

Addo R, Yuma P, Barrera I, Layton D.
PMID: 33751632
J Community Psychol. 2022 Jan;50(1):238-249. doi: 10.1002/jcop.22548. Epub 2021 Mar 22.

This study explored the social network properties and the correlates between social networks and subjective wellbeing of adults (N = 80) in a Housing First (HF) program. Using structured interviews, participants' social network properties were assessed. Bivariate correlations and...

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Addo R, Yuma P, Barrera I, et al. Social networks and subjective wellbeing of adults in a Housing First program. J Community Psychol. 2021;50(1):238-249doi: 10.1002/jcop.22548.
Addo, R., Yuma, P., Barrera, I., & Layton, D. (2022). Social networks and subjective wellbeing of adults in a Housing First program. Journal of community psychology, 50(1), 238-249. https://doi.org/10.1002/jcop.22548
Addo, Reuben, et al. "Social networks and subjective wellbeing of adults in a Housing First program." Journal of community psychology vol. 50,1 (2022): 238-249. doi: https://doi.org/10.1002/jcop.22548
Addo R, Yuma P, Barrera I, Layton D. Social networks and subjective wellbeing of adults in a Housing First program. J Community Psychol. 2022 Jan;50(1):238-249. doi: 10.1002/jcop.22548. Epub 2021 Mar 22. PMID: 33751632.
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