Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 25 to 36 of 251 entries
Sorted by: Best Match Show Resources per page
What Is the Profile of Overweight Individuals Who Are Unsuccessful Responders to a Low-Energy Diet? A PREVIEW Sub-study.

Frontiers in nutrition

Tremblay A, Fogelholm M, Jalo E, Westerterp-Plantenga MS, Adam TC, Huttunen-Lenz M, Stratton G, Lam T, Handjieva-Darlenska T, Handjiev S, Martinez JA, Macdonald IA, Simpson EJ, Brand-Miller J, Muirhead R, Poppitt SD, Silvestre MP, Larsen TM, Vestentoft PS, Schlicht W, Drapeau V, Raben A.
PMID: 34796192
Front Nutr. 2021 Nov 02;8:707682. doi: 10.3389/fnut.2021.707682. eCollection 2021.

This study was performed to evaluate the profile of overweight individuals with pre-diabetes enrolled in PREVIEW who were unable to achieve a body weight loss of ≥8% of the baseline value in response to a 2-month low-energy diet (LED)....

Dietary carbohydrate restriction augments weight loss-induced improvements in glycaemic control and liver fat in individuals with type 2 diabetes: a randomised controlled trial.

Diabetologia

Thomsen MN, Skytte MJ, Samkani A, Carl MH, Weber P, Astrup A, Chabanova E, Fenger M, Frystyk J, Hartmann B, Holst JJ, Larsen TM, Madsbad S, Magkos F, Thomsen HS, Haugaard SB, Krarup T.
PMID: 34993571
Diabetologia. 2022 Jan 07; doi: 10.1007/s00125-021-05628-8. Epub 2022 Jan 07.

AIMS/HYPOTHESIS: Lifestyle modification and weight loss are cornerstones of type 2 diabetes management. However, carbohydrate restriction may have weight-independent beneficial effects on glycaemic control. This has been difficult to demonstrate because low-carbohydrate diets readily decrease body weight. We hypothesised...

Diagnostic accuracy of ultra-low-dose chest computed tomography in an emergency department.

Acta radiologica (Stockholm, Sweden : 1987)

Tækker M, Kristjánsdóttir B, Andersen MB, Fransen ML, Greisen PW, Laursen CB, Mussmann B, Posth S, Graumann O.
PMID: 33663246
Acta Radiol. 2021 Mar 04;284185121995804. doi: 10.1177/0284185121995804. Epub 2021 Mar 04.

BACKGROUND: This study examined whether ultra-low-dose chest computed tomography (ULD-CT) could improve detection of acute chest conditions.PURPOSE: To determine (i) whether diagnostic accuracy of ULD-CT is superior to supine chest X-ray (sCXR) for acute chest conditions and (ii) the...

Association of Psychobehavioral Variables With HOMA-IR and BMI Differs for Men and Women With Prediabetes in the PREVIEW Lifestyle Intervention.

Diabetes care

Adam TC, Drummen M, Macdonald I, Jalo E, Siig-Vestentoft P, Martinez JA, Handjiev-Darlenska T, Brand-Miller J, Poppitt S, Stratton G, Fogelholm M, Pietiläinen KH, Taylor M, Navas-Carretero S, Winkens B, Handjiev S, Muirhead R, Silvestre M, Swindell N, Huttunen-Lenz M, Schlicht W, Lam T, Sundvall J, Råman L, Feskens E, Larssen TM, Tremblay A, Raben A, Westerterp-Plantenga M.
PMID: 34088702
Diabetes Care. 2021 Jul;44(7):1491-1498. doi: 10.2337/dc21-0059. Epub 2021 Jun 04.

OBJECTIVE: Stress, sleep, eating behavior, and physical activity are associated with weight change and insulin resistance (IR). The aim of this analysis was the assessment of the overall and sex-specific associations of psychobehavioral variables throughout the 3-year PREVIEW intervention...

The association between sleep quality, preoperative risk factors for chronic postoperative pain and postoperative pain intensity 12 months after knee and hip arthroplasty.

British journal of pain

Boye Larsen D, Laursen M, Simonsen O, Arendt-Nielsen L, Petersen KK.
PMID: 34840796
Br J Pain. 2021 Nov;15(4):486-496. doi: 10.1177/20494637211005803. Epub 2021 Nov 15.

BACKGROUND: Chronic postoperative pain following total joint replacement (TJA) is a substantial clinical problem, and poor sleep may affect predictive factors for postoperative pain, such as pain catastrophizing. However, the magnitude of these associations is currently unknown. This exploratory...

Rational Design of Bright Long Fluorescence Lifetime Dyad Fluorophores for Single Molecule Imaging and Detection.

Journal of the American Chemical Society

Kacenauskaite L, Bisballe N, Mucci R, Santella M, Pullerits T, Chen J, Vosch T, Laursen BW.
PMID: 33427468
J Am Chem Soc. 2021 Jan 27;143(3):1377-1385. doi: 10.1021/jacs.0c10457. Epub 2021 Jan 11.

Increasing demand for detecting single molecules in challenging environments has raised the bar for the fluorophores used. To achieve better resolution and/or contrast in fluorescence microscopy, it is now essential to use bright and stable dyes with tailored photophysical...

The Association Between Cardiovascular Autonomic Function and Changes in Kidney and Myocardial Function in Type 2 Diabetes and Healthy Controls.

Frontiers in endocrinology

Laursen JC, Rasmussen IKB, Zobel EH, Hasbak P, von Scholten BJ, Holmvang L, Ripa RS, Hansen CS, Frimodt-Moeller M, Kjaer A, Rossing P, Hansen TW.
PMID: 34966359
Front Endocrinol (Lausanne). 2021 Dec 13;12:780679. doi: 10.3389/fendo.2021.780679. eCollection 2021.

RESULTS: Mean age at inclusion was 61 ± 10 years and 36% were female. Mean follow up time was 6 ± 0 years. A lower response in heart rate to the Valsalva test (corresponding to weaker autonomic function) was...

SARS-CoV-2 Spike triggers barrier dysfunction and vascular leak via integrins and TGF-β signaling.

bioRxiv : the preprint server for biology

Biering SB, de Sousa FTG, Tjang LV, Pahmeier F, Ruan R, Blanc SF, Patel TS, Worthington CM, Glasner DR, Castillo-Rojas B, Servellita V, Lo NTN, Wong MP, Warnes CM, Sandoval DR, Clausen TM, Santos YA, Ortega V, Aguilar HC, Esko JD, Chui CY, Pak JE, Beatty PR, Harris E.
PMID: 34931188
bioRxiv. 2021 Dec 13; doi: 10.1101/2021.12.10.472112.

Severe COVID-19 is associated with epithelial and endothelial barrier dysfunction within the lung as well as in distal organs. While it is appreciated that an exaggerated inflammatory response is associated with barrier dysfunction, the triggers of this pathology are...

Membrane anchoring facilitates colocalization of enzymes in plant cytochrome P450 redox systems.

Communications biology

Laursen T, Lam HYM, Sørensen KK, Tian P, Hansen CC, Groves JT, Jensen KJ, Christensen SM.
PMID: 34504298
Commun Biol. 2021 Sep 09;4(1):1057. doi: 10.1038/s42003-021-02604-1.

Plant metabolism depends on cascade reactions mediated by dynamic enzyme assemblies known as metabolons. In this context, the cytochrome P450 (P450) superfamily catalyze key reactions underpinning the unique diversity of bioactive compounds. In contrast to their soluble bacterial counterparts,...

Pyrolytic carbon resonators for micromechanical thermal analysis.

Microsystems & nanoengineering

Nguyen LQ, Larsen PE, Larsen T, Goswami SB, Villanueva LG, Boisen A, Keller SS.
PMID: 31646000
Microsyst Nanoeng. 2019 Oct 21;5:58. doi: 10.1038/s41378-019-0094-x. eCollection 2019.

Thermal analysis is essential for the characterization of polymers and drugs. However, the currently established methods require a large amount of sample. Here, we present pyrolytic carbon resonators as promising tools for micromechanical thermal analysis (MTA) of nanograms of...

Systemic Corticosteroids and the Risk of Venous Thromboembolism in Patients with Severe COPD: A Nationwide Study of 30,473 Outpatients.

Biomedicines

Rastoder E, Sivapalan P, Eklöf J, Saeed MI, Jordan AS, Meteran H, Tønnesen L, Biering-Sørensen T, Løkke A, Seersholm N, Lynghøj Nielsen T, Carlsen J, Janner J, Godtfredsen N, Bodtger U, Laursen CB, Hilberg O, Knop FK, Priemé H, Ingebrigtsen TS, Gottlieb V, Wilcke JT, Stæhr Jensen JU.
PMID: 34440079
Biomedicines. 2021 Jul 23;9(8). doi: 10.3390/biomedicines9080874.

Due to frequent exacerbations, many patients with chronic obstructive pulmonary disease (COPD) are exposed to oral corticosteroids (OCS), which may be thrombogenic. We evaluated the risk of hospitalisation with venous thromboembolism (VTE) and death in patients with acute exacerbation...

Nature and prevalence of combinations of mental disorders and their association with excess mortality in a population-based cohort study.

World psychiatry : official journal of the World Psychiatric Association (WPA)

Plana-Ripoll O, Musliner KL, Dalsgaard S, Momen NC, Weye N, Christensen MK, Agerbo E, Iburg KM, Laursen TM, Mortensen PB, Pedersen CB, Petersen LV, Santomauro DF, Vilhjálmsson BJ, Whiteford HA, McGrath JJ.
PMID: 32931098
World Psychiatry. 2020 Oct;19(3):339-349. doi: 10.1002/wps.20802.

The nature and prevalence of combinations of mental disorders and their associations with premature mortality have never been reported in a comprehensive way. We describe the most common combinations of mental disorders and estimate excess mortality associated with these...

Showing 25 to 36 of 251 entries