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Cognitive profiling and proteomic analysis of the modafinil analogue S-CE-123 in experienced aged rats.

Scientific reports

Gyertyán I, Lubec J, Ernyey AJ, Gerner C, Kassai F, Kalaba P, Kozma K, Cobankovic I, Brenner G, Wackerlig J, Franschitz E, Urban E, Langer T, Malikovic J, Lubec G.
PMID: 34907284
Sci Rep. 2021 Dec 14;11(1):23962. doi: 10.1038/s41598-021-03372-y.

The lack of novel cognitive enhancer drugs in the clinic highlights the prediction problems of animal assays. The objective of the current study was to test a putative cognitive enhancer in a rodent cognitive test system with improved translational...

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Gyertyán I, Lubec J, Ernyey AJ, et al. Cognitive profiling and proteomic analysis of the modafinil analogue S-CE-123 in experienced aged rats. Sci Rep. 2021;11(1):23962doi: 10.1038/s41598-021-03372-y.
Gyertyán, I., Lubec, J., Ernyey, A. J., Gerner, C., Kassai, F., Kalaba, P., Kozma, K., Cobankovic, I., Brenner, G., Wackerlig, J., Franschitz, E., Urban, E., Langer, T., Malikovic, J., & Lubec, G. (2021). Cognitive profiling and proteomic analysis of the modafinil analogue S-CE-123 in experienced aged rats. Scientific reports, 11(1), 23962. https://doi.org/10.1038/s41598-021-03372-y
Gyertyán, István, et al. "Cognitive profiling and proteomic analysis of the modafinil analogue S-CE-123 in experienced aged rats." Scientific reports vol. 11,1 (2021): 23962. doi: https://doi.org/10.1038/s41598-021-03372-y
Gyertyán I, Lubec J, Ernyey AJ, Gerner C, Kassai F, Kalaba P, Kozma K, Cobankovic I, Brenner G, Wackerlig J, Franschitz E, Urban E, Langer T, Malikovic J, Lubec G. Cognitive profiling and proteomic analysis of the modafinil analogue S-CE-123 in experienced aged rats. Sci Rep. 2021 Dec 14;11(1):23962. doi: 10.1038/s41598-021-03372-y. PMID: 34907284; PMCID: PMC8671572.
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A Phase I Study of an MPS1 Inhibitor (BAY 1217389) in Combination with Paclitaxel Using a Novel Randomized Continual Reassessment Method for Dose Escalation.

Clinical cancer research : an official journal of the American Association for Cancer Research

Atrafi F, Boix O, Subbiah V, Diamond JR, Chawla SP, Tolcher AW, LoRusso PM, Eder JP, Gutierrez M, Sankhala K, Rajagopalan P, Genvresse I, Langer S, Mathijssen RHJ, Verweij J, Bruns I, Lolkema MP.
PMID: 34518310
Clin Cancer Res. 2021 Dec 01;27(23):6366-6375. doi: 10.1158/1078-0432.CCR-20-4185. Epub 2021 Sep 13.

PURPOSE: Monopolar spindle 1 (MPS1) kinase inhibitor, BAY 1217389 (BAY) synergizes with paclitaxel. This phase I study assessed the combination of BAY with paclitaxel using a novel randomized continuous reassessment method (rCRM) to improve dose determination.PATIENTS AND METHODS: Patients...

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Atrafi F, Boix O, Subbiah V, et al. A Phase I Study of an MPS1 Inhibitor (BAY 1217389) in Combination with Paclitaxel Using a Novel Randomized Continual Reassessment Method for Dose Escalation. Clin Cancer Res. 2021;27(23):6366-6375doi: 10.1158/1078-0432.CCR-20-4185.
Atrafi, F., Boix, O., Subbiah, V., Diamond, J. R., Chawla, S. P., Tolcher, A. W., LoRusso, P. M., Eder, J. P., Gutierrez, M., Sankhala, K., Rajagopalan, P., Genvresse, I., Langer, S., Mathijssen, R. H. J., Verweij, J., Bruns, I., & Lolkema, M. P. (2021). A Phase I Study of an MPS1 Inhibitor (BAY 1217389) in Combination with Paclitaxel Using a Novel Randomized Continual Reassessment Method for Dose Escalation. Clinical cancer research : an official journal of the American Association for Cancer Research, 27(23), 6366-6375. https://doi.org/10.1158/1078-0432.CCR-20-4185
Atrafi, Florence, et al. "A Phase I Study of an MPS1 Inhibitor (BAY 1217389) in Combination with Paclitaxel Using a Novel Randomized Continual Reassessment Method for Dose Escalation." Clinical cancer research : an official journal of the American Association for Cancer Research vol. 27,23 (2021): 6366-6375. doi: https://doi.org/10.1158/1078-0432.CCR-20-4185
Atrafi F, Boix O, Subbiah V, Diamond JR, Chawla SP, Tolcher AW, LoRusso PM, Eder JP, Gutierrez M, Sankhala K, Rajagopalan P, Genvresse I, Langer S, Mathijssen RHJ, Verweij J, Bruns I, Lolkema MP. A Phase I Study of an MPS1 Inhibitor (BAY 1217389) in Combination with Paclitaxel Using a Novel Randomized Continual Reassessment Method for Dose Escalation. Clin Cancer Res. 2021 Dec 01;27(23):6366-6375. doi: 10.1158/1078-0432.CCR-20-4185. Epub 2021 Sep 13. PMID: 34518310.
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[Standardized structured reports for gastrointestinal tumors].

Der Pathologe

Hewer E, Rump A, Langer R.
PMID: 34609569
Pathologe. 2021 Oct 05; doi: 10.1007/s00292-021-00986-x. Epub 2021 Oct 05.

Synoptic reporting in pathology as opposed to traditional narrative reporting is defined by a laboratory value-like format and use of standardized checklists. It contributes to completeness and comprehensibility of pathology reports and ultimately patient care. As of today, two...

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Hewer E, Rump A, Langer R. Standardisierte strukturierte Befundberichte gastrointestinaler Tumoren. [Standardized structured reports for gastrointestinal tumors]. Pathologe. 2021;doi: 10.1007/s00292-021-00986-x.
Hewer, E., Rump, A., & Langer, R. (2021). Standardisierte strukturierte Befundberichte gastrointestinaler Tumoren. [Standardized structured reports for gastrointestinal tumors]. Der Pathologe, . https://doi.org/10.1007/s00292-021-00986-x
Hewer, Ekkehard, et al. "Standardisierte strukturierte Befundberichte gastrointestinaler Tumoren." [Standardized structured reports for gastrointestinal tumors]. Der Pathologe vol. (2021). doi: https://doi.org/10.1007/s00292-021-00986-x
Hewer E, Rump A, Langer R. Standardisierte strukturierte Befundberichte gastrointestinaler Tumoren. [Standardized structured reports for gastrointestinal tumors]. Pathologe. 2021 Oct 05; doi: 10.1007/s00292-021-00986-x. Epub 2021 Oct 05. German. PMID: 34609569.
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Accuracy of Physicians in Differentiating Type 1 and Type 2 Myocardial Infarction Based on Clinical Information.

CJC open

Borges FK, Sheth T, Patel A, Marcucci M, Yung T, Langer T, Alboim C, Polanczyk CA, Germini F, Azeredo-da-Silva AF, Sloan E, Kaila K, Ree R, Bertoletti A, Vedovati MC, Galzerano A, Spence J, Devereaux PJ.
PMID: 33305218
CJC Open. 2020 Jul 17;2(6):577-584. doi: 10.1016/j.cjco.2020.07.009. eCollection 2020 Nov.

BACKGROUND: Physicians commonly judge whether a myocardial infarction (MI) is type 1 (thrombotic) vs type 2 (supply/demand mismatch) based on clinical information. Little is known about the accuracy of physicians' clinical judgement in this regard. We aimed to determine...

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Borges FK, Sheth T, Patel A, et al. Accuracy of Physicians in Differentiating Type 1 and Type 2 Myocardial Infarction Based on Clinical Information. CJC Open. 2020;2(6):577-584doi: 10.1016/j.cjco.2020.07.009.
Borges, F. K., Sheth, T., Patel, A., Marcucci, M., Yung, T., Langer, T., Alboim, C., Polanczyk, C. A., Germini, F., Azeredo-da-Silva, A. F., Sloan, E., Kaila, K., Ree, R., Bertoletti, A., Vedovati, M. C., Galzerano, A., Spence, J., & Devereaux, P. J. (2020). Accuracy of Physicians in Differentiating Type 1 and Type 2 Myocardial Infarction Based on Clinical Information. CJC open, 2(6), 577-584. https://doi.org/10.1016/j.cjco.2020.07.009
Borges, Flavia K, et al. "Accuracy of Physicians in Differentiating Type 1 and Type 2 Myocardial Infarction Based on Clinical Information." CJC open vol. 2,6 (2020): 577-584. doi: https://doi.org/10.1016/j.cjco.2020.07.009
Borges FK, Sheth T, Patel A, Marcucci M, Yung T, Langer T, Alboim C, Polanczyk CA, Germini F, Azeredo-da-Silva AF, Sloan E, Kaila K, Ree R, Bertoletti A, Vedovati MC, Galzerano A, Spence J, Devereaux PJ. Accuracy of Physicians in Differentiating Type 1 and Type 2 Myocardial Infarction Based on Clinical Information. CJC Open. 2020 Jul 17;2(6):577-584. doi: 10.1016/j.cjco.2020.07.009. eCollection 2020 Nov. PMID: 33305218; PMCID: PMC7711010.
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Contrast inversion of the h-BN nanomesh investigated by nc-AFM and Kelvin probe force microscopy.

Journal of physics. Condensed matter : an Institute of Physics journal

Koch S, Langer M, Kawai S, Meyer E, Glatzel T.
PMID: 22820852
J Phys Condens Matter. 2012 Aug 08;24(31):314212. doi: 10.1088/0953-8984/24/31/314212. Epub 2012 Jul 20.

Single sheets of hexagonal boron nitride (h-BN) on transition metals provide a model system for layered insulating materials as well as a functional substrate for molecules and metal clusters. The progress in the understanding of h-BN layers on transition...

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Koch S, Langer M, Kawai S, et al. Contrast inversion of the h-BN nanomesh investigated by nc-AFM and Kelvin probe force microscopy. J Phys Condens Matter. 2012;24(31):314212doi: 10.1088/0953-8984/24/31/314212.
Koch, S., Langer, M., Kawai, S., Meyer, E., & Glatzel, T. (2012). Contrast inversion of the h-BN nanomesh investigated by nc-AFM and Kelvin probe force microscopy. Journal of physics. Condensed matter : an Institute of Physics journal, 24(31), 314212. https://doi.org/10.1088/0953-8984/24/31/314212
Koch, S, et al. "Contrast inversion of the h-BN nanomesh investigated by nc-AFM and Kelvin probe force microscopy." Journal of physics. Condensed matter : an Institute of Physics journal vol. 24,31 (2012): 314212. doi: https://doi.org/10.1088/0953-8984/24/31/314212
Koch S, Langer M, Kawai S, Meyer E, Glatzel T. Contrast inversion of the h-BN nanomesh investigated by nc-AFM and Kelvin probe force microscopy. J Phys Condens Matter. 2012 Aug 08;24(31):314212. doi: 10.1088/0953-8984/24/31/314212. Epub 2012 Jul 20. PMID: 22820852.
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Greedy 3-Point Search (G3PS)-A Novel Algorithm for Pharmacophore Alignment.

Molecules (Basel, Switzerland)

Permann C, Seidel T, Langer T.
PMID: 34885781
Molecules. 2021 Nov 27;26(23). doi: 10.3390/molecules26237201.

Chemical features of small molecules can be abstracted to 3D pharmacophore models, which are easy to generate, interpret, and adapt by medicinal chemists. Three-dimensional pharmacophores can be used to efficiently match and align molecules according to their chemical feature...

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Permann C, Seidel T, Langer T. Greedy 3-Point Search (G3PS)-A Novel Algorithm for Pharmacophore Alignment. Molecules. 2021;26(23)doi: 10.3390/molecules26237201.
Permann, C., Seidel, T., & Langer, T. (2021). Greedy 3-Point Search (G3PS)-A Novel Algorithm for Pharmacophore Alignment. Molecules (Basel, Switzerland), 26(23), . https://doi.org/10.3390/molecules26237201
Permann, Christian, et al. "Greedy 3-Point Search (G3PS)-A Novel Algorithm for Pharmacophore Alignment." Molecules (Basel, Switzerland) vol. 26,23 (2021). doi: https://doi.org/10.3390/molecules26237201
Permann C, Seidel T, Langer T. Greedy 3-Point Search (G3PS)-A Novel Algorithm for Pharmacophore Alignment. Molecules. 2021 Nov 27;26(23). doi: 10.3390/molecules26237201. PMID: 34885781; PMCID: PMC8658842.
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Dataset for the reporting of carcinoma of the esophagus in resection specimens: recommendations from the International Collaboration on Cancer Reporting.

Human pathology

Lam AK, Bourke MJ, Chen R, Fiocca R, Fujishima F, Fujii S, Jansen M, Kumarasinghe P, Langer R, Law S, Meijer SL, Muldoon C, Novelli M, Shi C, Tang L, Nagtegaal ID.
PMID: 33992659
Hum Pathol. 2021 Aug;114:54-65. doi: 10.1016/j.humpath.2021.05.003. Epub 2021 May 13.

BACKGROUND AND OBJECTIVES: A standardized data set for esophageal carcinoma pathology reporting was developed based on the approach of the International Collaboration on Cancer Reporting (ICCR) for the purpose of improving cancer patient outcomes and international benchmarking in cancer...

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Lam AK, Bourke MJ, Chen R, et al. Dataset for the reporting of carcinoma of the esophagus in resection specimens: recommendations from the International Collaboration on Cancer Reporting. Hum Pathol. 2021;114:54-65doi: 10.1016/j.humpath.2021.05.003.
Lam, A. K., Bourke, M. J., Chen, R., Fiocca, R., Fujishima, F., Fujii, S., Jansen, M., Kumarasinghe, P., Langer, R., Law, S., Meijer, S. L., Muldoon, C., Novelli, M., Shi, C., Tang, L., & Nagtegaal, I. D. (2021). Dataset for the reporting of carcinoma of the esophagus in resection specimens: recommendations from the International Collaboration on Cancer Reporting. Human pathology, 11454-65. https://doi.org/10.1016/j.humpath.2021.05.003
Lam, Alfred K, et al. "Dataset for the reporting of carcinoma of the esophagus in resection specimens: recommendations from the International Collaboration on Cancer Reporting." Human pathology vol. 114 (2021): 54-65. doi: https://doi.org/10.1016/j.humpath.2021.05.003
Lam AK, Bourke MJ, Chen R, Fiocca R, Fujishima F, Fujii S, Jansen M, Kumarasinghe P, Langer R, Law S, Meijer SL, Muldoon C, Novelli M, Shi C, Tang L, Nagtegaal ID. Dataset for the reporting of carcinoma of the esophagus in resection specimens: recommendations from the International Collaboration on Cancer Reporting. Hum Pathol. 2021 Aug;114:54-65. doi: 10.1016/j.humpath.2021.05.003. Epub 2021 May 13. PMID: 33992659.
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Acid-base effects of regional citrate anticoagulation for continuous renal replacement therapy: don't judge the technique only by its name, every bag is not the same!.

Minerva anestesiologica

Langer T, Giani M.
PMID: 34874133
Minerva Anestesiol. 2021 Dec;87(12):1281-1283. doi: 10.23736/S0375-9393.21.16207-8.

No abstract available.

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Langer T, Giani M. Acid-base effects of regional citrate anticoagulation for continuous renal replacement therapy: don't judge the technique only by its name, every bag is not the same!. Minerva Anestesiol. 2021;87(12):1281-1283doi: 10.23736/S0375-9393.21.16207-8.
Langer, T., & Giani, M. (2021). Acid-base effects of regional citrate anticoagulation for continuous renal replacement therapy: don't judge the technique only by its name, every bag is not the same!. Minerva anestesiologica, 87(12), 1281-1283. https://doi.org/10.23736/S0375-9393.21.16207-8
Langer, Thomas, and Giani, Marco. "Acid-base effects of regional citrate anticoagulation for continuous renal replacement therapy: don't judge the technique only by its name, every bag is not the same!." Minerva anestesiologica vol. 87,12 (2021): 1281-1283. doi: https://doi.org/10.23736/S0375-9393.21.16207-8
Langer T, Giani M. Acid-base effects of regional citrate anticoagulation for continuous renal replacement therapy: don't judge the technique only by its name, every bag is not the same!. Minerva Anestesiol. 2021 Dec;87(12):1281-1283. doi: 10.23736/S0375-9393.21.16207-8. PMID: 34874133.
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Showing 1549 to 1556 of 1556 entries