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Showing 25 to 36 of 166 entries
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Mutations of N1 Riboswitch Affect its Dynamics and Recognition by Neomycin Through Conformational Selection.

Frontiers in molecular biosciences

Chyży P, Kulik M, Re S, Sugita Y, Trylska J.
PMID: 33708793
Front Mol Biosci. 2021 Feb 18;8:633130. doi: 10.3389/fmolb.2021.633130. eCollection 2021.

Short, structured fragments of non-coding mRNA may act as molecular switches upon binding specific ligands, regulating the translation of proteins encoded downstream this mRNA sequence. One switch, called riboswitch N1, is regulated by aminoglycosides such as neomycin. Nucleobase mutations...

Eating Disorders, Pregnancy, and the Postpartum Period: Findings from the Norwegian Mother and Child Cohort Study (MoBa).

Norsk epidemiologi = Norwegian journal of epidemiology

Watson HJ, Torgersen L, Zerwas S, Reichborn-Kjennerud T, Knoph C, Stoltenberg C, Siega-Riz AM, Von Holle A, Hamer RM, Meltzer H, Ferguson EH, Haugen M, Magnus P, Kuhns R, Bulik CM.
PMID: 27110061
Nor Epidemiol. 2014 Jan 01;24(1):51-62. doi: 10.5324/nje.v24i1-2.1758.

This review summarizes studies on eating disorders in pregnancy and the postpartum period that have been conducted as part of the broader Norwegian Mother and Child Cohort Study (MoBa). Prior to the 2000s, empirical literature on eating disorders in...

Codecaying Dark Matter.

Physical review letters

Dror JA, Kuflik E, Ng WH.
PMID: 27911563
Phys Rev Lett. 2016 Nov 18;117(21):211801. doi: 10.1103/PhysRevLett.117.211801. Epub 2016 Nov 18.

We propose a new mechanism for thermal dark matter freeze-out, called codecaying dark matter. Multicomponent dark sectors with degenerate particles and out-of-equilibrium decays can codecay to obtain the observed relic density. The dark matter density is exponentially depleted through...

A bilayer small diameter .

Biomicrofluidics

Hoganson DM, Finkelstein EB, Owens GE, Hsiao JC, Eng KY, Kulig KM, Kim ES, Kniazeva T, Pomerantseva I, Neville CM, Turk JR, Fermini B, Borenstein JT, Vacanti JP.
PMID: 27795748
Biomicrofluidics. 2016 Oct 12;10(5):054116. doi: 10.1063/1.4964814. eCollection 2016 Sep.

In pre-clinical safety studies, drug-induced vascular injury (DIVI) is defined as an adverse response to a drug characterized by degenerative and hyperplastic changes of endothelial cells and vascular smooth muscle cells. Inflammation may also be seen, along with extravasation...

The Genetic Architecture of Obsessive-Compulsive Disorder: Contribution of Liability to OCD From Alleles Across the Frequency Spectrum.

The American journal of psychiatry

Mahjani B, Klei L, Mattheisen M, Halvorsen MW, Reichenberg A, Roeder K, Pedersen NL, Boberg J, de Schipper E, Bulik CM, Landén M, Fundín B, Mataix-Cols D, Sandin S, Hultman CM, Crowley JJ, Buxbaum JD, Rück C, Devlin B, Grice DE.
PMID: 34789012
Am J Psychiatry. 2021 Nov 18;appiajp202121010101. doi: 10.1176/appi.ajp.2021.21010101. Epub 2021 Nov 18.

OBJECTIVE: Obsessive-compulsive disorder (OCD) is known to be substantially heritable; however, the contribution of genetic variation across the allele frequency spectrum to this heritability remains uncertain. The authors used two new homogeneous cohorts to estimate the heritability of OCD...

Differential Activity of APOBEC3F, APOBEC3G, and APOBEC3H in the Restriction of HIV-2.

Journal of molecular biology

Meissner ME, Willkomm NA, Lucas J, Arndt WG, Aitken SF, Julik EJ, Baliga S, Mansky LM.
PMID: 34774569
J Mol Biol. 2021 Nov 10;434(2):167355. doi: 10.1016/j.jmb.2021.167355. Epub 2021 Nov 10.

Human immunodeficiency virus (HIV) mutagenesis is driven by a variety of internal and external sources, including the host APOBEC3 (apolipoprotein B mRNA editing enzyme catalytic polypetide-like 3; A3) family of mutagenesis factors, which catalyze G-to-A transition mutations during virus...

Caries status of first-born child is a predictor for caries experience in younger siblings.

Clinical oral investigations

Grieshaber A, Haschemi AA, Waltimo T, Bornstein MM, Kulik EM.
PMID: 34196854
Clin Oral Investig. 2021 Jul 01; doi: 10.1007/s00784-021-04003-6. Epub 2021 Jul 01.

OBJECTIVES: This study analysed if children of families in need of dental interventions can be identified by using the caries status of the first-born child as a predictor for caries in younger siblings of the same family.MATERIAL AND METHODS:...

Interdental biofilm reduction and composition after use of an activated and inactivated side-to-side toothbrush - a proof-of-principle clinical study.

Clinical oral investigations

Difloe-Geisert JC, Fiedler S, Kulik EM, Schlueter N, Ganss C, Walter C.
PMID: 35018500
Clin Oral Investig. 2022 Jan 11; doi: 10.1007/s00784-021-04273-0. Epub 2022 Jan 11.

OBJECTIVES: To evaluate interdental biofilm reduction and composition after powered toothbrushing with a side-to-side (sonic) toothbrush compared to manual toothbrushing following single brushing exercises in periodontally healthy young adults.MATERIALS AND METHODS: All participants brushed with a side-to-side toothbrush without...

Gut feelings: A role for the intestinal microbiota in anorexia nervosa?.

The International journal of eating disorders

Kleiman SC, Carroll IM, Tarantino LM, Bulik CM.
PMID: 25639767
Int J Eat Disord. 2015 Jul;48(5):449-51. doi: 10.1002/eat.22394. Epub 2015 Jan 30.

No abstract available.

Percutaneous extraction of residual post-cholecystectomy gallstones through the T-tube tract.

Polish journal of radiology

Sobstyl J, Sojka M, Kuczyńska M, Światłowski Ł, Kuklik E, Jargiełło T.
PMID: 30627233
Pol J Radiol. 2018 May 07;83:e183-e188. doi: 10.5114/pjr.2018.75811. eCollection 2018.

PURPOSE: In the present study, the effectiveness and safety of minimally invasive percutaneous extraction of residual post-cholecystectomy gallstones through the T-tube tract were assessed.MATERIAL AND METHODS: Between 2000 and 2015, 12 patients (seven women and five men, mean age...

Familial co-aggregation of schizophrenia and eating disorders in Sweden and Denmark.

Molecular psychiatry

Zhang R, Larsen JT, Kuja-Halkola R, Thornton L, Yao S, Larsson H, Lichtenstein P, Petersen LV, Bulik CM, Bergen SE.
PMID: 32382133
Mol Psychiatry. 2021 Sep;26(9):5389-5397. doi: 10.1038/s41380-020-0749-x. Epub 2020 May 07.

Eating disorders and schizophrenia are both moderately to highly heritable and share significant genetic risk despite distinct diagnostic criteria. Large-scale family studies on the co-aggregation of these disorders are lacking. Thus, we aimed to estimate the co-occurrence and familial...

Tolerance and Persister Formation in Oral Streptococci.

Antibiotics (Basel, Switzerland)

Suppiger S, Astasov-Frauenhoffer M, Schweizer I, Waltimo T, Kulik EM.
PMID: 32276310
Antibiotics (Basel). 2020 Apr 08;9(4). doi: 10.3390/antibiotics9040167.

The aim of this study was to analyze the potential influence of long-term exposure in subinhibitory concentrations of chlorhexidine on the emergence of tolerant and/or persistent cells in oral streptococci. The two oral streptococcal isolates

Showing 25 to 36 of 166 entries