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Showing 229 to 239 of 239 entries
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Using Biometric Sensor Data to Monitor Cancer Patients During Radiotherapy: Protocol for the OncoWatch Feasibility Study.

JMIR research protocols

Holländer-Mieritz C, Vogelius IR, Kristensen CA, Green A, Rindum JL, Pappot H.
PMID: 33983123
JMIR Res Protoc. 2021 May 13;10(5):e26096. doi: 10.2196/26096.

BACKGROUND: Patients with head and neck cancer (HNC) experience severe side effects during radiotherapy (RT). Ongoing technological advances in wearable biometric sensors allow for the collection of objective data (eg, physical activity and heart rate), which might, in the...

Treatment outcomes and survival following definitive (chemo)radiotherapy in HPV-positive oropharynx cancer: Large-scale comparison of DAHANCA vs PMH cohorts.

International journal of cancer

Lassen P, Huang SH, Su J, Waldron J, Andersen M, Primdahl H, Johansen J, Kristensen CA, Andersen E, Eriksen JG, Hansen CR, Alsner J, Lilja-Fisher J, Bratman SV, Ringash J, Kim J, Hope A, Spreafico A, de Almeida J, Xu W, O'Sullivan B, Overgaard J.
PMID: 34792199
Int J Cancer. 2021 Nov 18; doi: 10.1002/ijc.33876. Epub 2021 Nov 18.

We compare outcomes in two large-scale contemporaneously treated HPV-positive (HPV+) oropharynx cancer (OPC) cohorts treated with definitive radiotherapy/chemoradiotherapy (RT/CRT). p16-confirmed HPV+ OPC treated between 2007 and 2015 at PMH and DAHANCA were identified. Locoregional failure (LRF), distant metastasis (DM),...

Managing Known Difficult Airways in Obstetric Patients Using a Flexible Bronchoscope and IRRIS: A Case-Illustrated Guide for Nonexpert Anesthesiologists, without Surgical Backup.

Case reports in anesthesiology

Hannig KE, Hauritz RW, Jessen C, Herzog J, Grejs AM, Kristensen MS.
PMID: 34659836
Case Rep Anesthesiol. 2021 Oct 08;2021:6778805. doi: 10.1155/2021/6778805. eCollection 2021.

Pregnancy is associated with anatomical and physiological changes leading to potential difficult airway management. Some pregnant women have known difficult airways and cannot be intubated even with a hyperangulated videolaryngoscope. If neuraxial techniques are also impossible, awake tracheal intubation...

FDG-PET/CT identified distant metastases and synchronous cancer in squamous cell carcinoma of the head and neck: the impact of smoking and P16-s.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

Bernsdorf M, Loft A, Berthelsen AK, Kjems J, Vogelius IR, von Buchwald C, Kristensen CA, Gothelf AB, Friborg J.
PMID: 34075488
Eur Arch Otorhinolaryngol. 2022 Jan;279(1):521-526. doi: 10.1007/s00405-021-06890-7. Epub 2021 Jun 01.

PURPOSE: Whole-body FDG-PET-CT is widely used at diagnosis of squamous cell carcinoma of the head and neck (SCCHN) but may identify suspicious lesions outside the neck that require investigation. This study evaluated the impact of smoking and P16-status on...

Altered lipid metabolism marks glioblastoma stem and non-stem cells in separate tumor niches.

Acta neuropathologica communications

Shakya S, Gromovsky AD, Hale JS, Knudsen AM, Prager B, Wallace LC, Penalva LOF, Brown HA, Kristensen BW, Rich JN, Lathia JD, Brown JM, Hubert CG.
PMID: 34059134
Acta Neuropathol Commun. 2021 May 31;9(1):101. doi: 10.1186/s40478-021-01205-7.

Glioblastoma (GBM) displays marked cellular and metabolic heterogeneity that varies among cellular microenvironments within a tumor. Metabolic targeting has long been advocated as a therapy against many tumors including GBM, but how lipid metabolism is altered to suit different...

Are fatty acids associated with disease activity and biomarkers in patients with psoriatic arthritis? Data from a multicenter clinical trial.

Rheumatology international

Kristensen S, Nielsen SH, Schmidt EB, Bay-Jensen AC, Karsdal MA, Christensen JH.
PMID: 34327558
Rheumatol Int. 2021 Jul 29; doi: 10.1007/s00296-021-04953-w. Epub 2021 Jul 29.

The pathogenesis of psoriatic arthritis (PsA) involves inflammation and bone and soft tissue turnover. Dietary fatty acids have previously been associated with pro-inflammatory effects induced by saturated fatty acids (SFA) and anti-inflammatory effects achieved by at least some polyunsaturated...

The Prognostic Value of Methylation Signatures and .

Cancers

Meta R, Boldt HB, Kristensen BW, Sahm F, Sjursen W, Torp SH.
PMID: 33809258
Cancers (Basel). 2021 Mar 12;13(6). doi: 10.3390/cancers13061262.

No abstract available.

Pronounced Plastic and Evolutionary Responses to Unpredictable Thermal Fluctuations in .

Frontiers in genetics

Sørensen JG, Manenti T, Bechsgaard JS, Schou MF, Kristensen TN, Loeschcke V.
PMID: 33193631
Front Genet. 2020 Oct 28;11:555843. doi: 10.3389/fgene.2020.555843. eCollection 2020.

Organisms are exposed to temperatures that vary, for example on diurnal and seasonal time scales. Thus, the ability to behaviorally and/or physiologically respond to variation in temperatures is a fundamental requirement for long-term persistence. Studies on thermal biology in...

Non-specific effects of maternal and offspring rabies vaccination on mortality and antibiotic use in a Danish pig herd: A randomized trial.

Vaccine

Jensen KJ, Tolstrup LK, Knobel DL, Aaby P, Jungersen G, Larsen LE, Kristensen CS, Benn CS.
PMID: 33840563
Vaccine. 2021 Apr 09; doi: 10.1016/j.vaccine.2021.03.083. Epub 2021 Apr 09.

INTRODUCTION: Human non-live vaccines have been associated with detrimental non-specific effects (NSE), particularly in females. A large trial found 2-fold increased overall mortality in girls receiving a new malaria vaccine compared to the rabies vaccine used as a coontrol;...

Layer-specific longitudinal strain detects transmural dysfunction in chronic severe aortic regurgitation before and after aortic valve surgery.

The international journal of cardiovascular imaging

Grund FF, Kristensen CB, Bahrami HSZ, Mogelvang R, Hassager C.
PMID: 34928462
Int J Cardiovasc Imaging. 2021 Dec 20; doi: 10.1007/s10554-021-02492-w. Epub 2021 Dec 20.

To assess if layer-specific longitudinal strain (LS) provides incremental diagnostic and prognostic value compared to global longitudinal strain (GLS) in patients with chronic severe aortic regurgitation (AR) scheduled for aortic valve surgery. Forty-one patients were examined with speckle tracking...

Three-dimensional missense tolerance ratio analysis.

Genome research

Perszyk RE, Kristensen AS, Lyuboslavsky P, Traynelis SF.
PMID: 34301626
Genome Res. 2021 Aug;31(8):1447-1461. doi: 10.1101/gr.275528.121. Epub 2021 Jul 22.

A wealth of genetic information is available describing single-nucleotide variants in the human population that appear to be well-tolerated and in and of themselves do not confer disease. These variant data sets contain signatures about the protein structure-function relationships...

Showing 229 to 239 of 239 entries