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Showing 25 to 36 of 221 entries
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Crystal structure of human 14-3-3ζ complexed with the noncanonical phosphopeptide from proapoptotic BAD.

Biochemical and biophysical research communications

Sluchanko NN, Tugaeva KV, Gushchin I, Remeeva A, Kovalev K, Cooley RB.
PMID: 34735870
Biochem Biophys Res Commun. 2021 Oct 26;583:100-105. doi: 10.1016/j.bbrc.2021.10.053. Epub 2021 Oct 26.

Several signaling pathways control phosphorylation of the proapoptotic protein BAD and its phosphorylation-dependent association with 14-3-3 proteins in the cytoplasm. The stability of the 14-3-3/BAD complex determines the cell fate: unphosphorylated BAD escapes from 14-3-3, migrates to the mitochondria...

Synthesis of .

Organic letters

Collin DE, Kovacic K, Light ME, Linclau B.
PMID: 34133174
Org Lett. 2021 Jun 16; doi: 10.1021/acs.orglett.1c01702. Epub 2021 Jun 16.

The cubane ring has received intense attention as a 3D benzene isostere and scaffold. Mono- and 1,4-disubstituted cubanes are well-described. Here we report a practical procedure for a direct radical-mediated chlorocarbonylation process initially reported by Bashir-Hashemi, to access a...

Determining diabetic kidney disease severity using traditional Chinese medicine syndrome classification.

Singapore medical journal

Lam ARL, Zheng HF, Teo KK, Xin XH, Tan CS, Kovalik JP, Ghosh S, Tan HC.
PMID: 34717305
Singapore Med J. 2021 Oct 31; doi: 10.11622/smedj.2021179. Epub 2021 Oct 31.

No abstract available.

Stereotactic radiotherapy for reirradiation of head and neck cancer: Dosimetric details matter.

Head & neck

West N, Kelly C, Kovarik J, Iqbal MS.
PMID: 34766399
Head Neck. 2022 Jan;44(1):287-288. doi: 10.1002/hed.26925. Epub 2021 Nov 12.

No abstract available.

Stereotactic radiotherapy for reirradiation of head and neck cancer: Dosimetric details matter.

Head & neck

West N, Kelly C, Kovarik J, Iqbal MS.
PMID: 34766399
Head Neck. 2022 Jan;44(1):287-288. doi: 10.1002/hed.26925. Epub 2021 Nov 12.

No abstract available.

Na.

Science advances

Alleva C, Kovalev K, Astashkin R, Berndt MI, Baeken C, Balandin T, Gordeliy V, Fahlke C, Machtens JP.
PMID: 33208356
Sci Adv. 2020 Nov 18;6(47). doi: 10.1126/sciadv.aba9854. Print 2020 Nov.

Excitatory amino acid transporters (EAATs) harness [Na

Author Correction: Small-wedge synchrotron and serial XFEL datasets for Cysteinyl leukotriene GPCRs.

Scientific data

Marin E, Luginina A, Gusach A, Kovalev K, Bukhdruker S, Khorn P, Polovinkin V, Lyapina E, Rogachev A, Gordeliy V, Mishin A, Cherezov V, Borshchevskiy V.
PMID: 33230124
Sci Data. 2020 Nov 23;7(1):419. doi: 10.1038/s41597-020-00759-w.

A Correction to this paper has been published: https://doi.org/10.1038/s41597-020-00759-w.

Rate and selectivity hysteresis during the carbon monoxide hydrogenation over promoted Co/MnOx catalysts.

Nature communications

Xiang Y, Kovarik L, Kruse N.
PMID: 31477697
Nat Commun. 2019 Sep 02;10(1):3953. doi: 10.1038/s41467-019-11836-z.

While cobalt-based catalysts have been used in industrial Fischer-Tropsch synthesis for decades, little is known about how the dynamics of the Co-Co

Cetuximab in the management of nasopharyngeal carcinoma - a narrative review.

The Journal of laryngology and otology

Iqbal MS, Wilkinson D, Tin A, Bossi P, Gradwell-Nelson L, Kovarik J, O'Hara J, Kelly C.
PMID: 31506113
J Laryngol Otol. 2019 Oct;133(10):843-855. doi: 10.1017/S0022215119001853. Epub 2019 Sep 11.

BACKGROUND: Concurrent chemotherapy with radiotherapy is the standard treatment for locoregionally advanced nasopharyngeal cancer. Cetuximab can be used in the treatment of head and neck squamous cell carcinoma. However, the randomised studies that led to approval for its use...

Imaging the Optical Fields of Functionalized Silver Nanowires through Molecular TERS.

The journal of physical chemistry letters

Bhattarai A, Crampton KT, Joly AG, Kovarik L, Hess WP, El-Khoury PZ.
PMID: 30517015
J Phys Chem Lett. 2018 Dec 20;9(24):7105-7109. doi: 10.1021/acs.jpclett.8b03324. Epub 2018 Dec 07.

We image 4-mercaptobenzonitrile-functionalized silver nanowires (∼20 nm diameter) through tip-enhanced Raman scattering (TERS). The enhanced local optical field-molecular interactions that govern the recorded hyperspectral TERS images are dissected through hybrid finite-difference time-domain density functional theory simulations. Our forward simulations...

Using Atom Dynamics to Map the Defect Structure Around an Impurity in Nano-Hematite.

The journal of physical chemistry letters

Ilton ES, Kovarik L, Nakouzi E, Mergelsberg ST, McBriarty ME, Bylaska EJ.
PMID: 33238102
J Phys Chem Lett. 2020 Dec 17;11(24):10396-10400. doi: 10.1021/acs.jpclett.0c02798. Epub 2020 Nov 25.

The bulk behavior of materials is often controlled by minor impurities that create nonperiodic localized defect structures due to ionic size, symmetry, and charge balance mismatches. Here, we used transmission electron microscopy (TEM) of atom-resolved dynamics to directly map...

Cranial nerve monitoring in endoscopic endonasal surgery of skull base tumors (observing of 23 cases).

Chinese neurosurgical journal

Shkarubo AN, Chernov IV, Ogurtsova AA, Chernov VE, Borisov OV, Koval KV, Andreev DN.
PMID: 32922898
Chin Neurosurg J. 2018 Dec 21;4:38. doi: 10.1186/s41016-018-0146-3. eCollection 2018.

BACKGROUND: Preservation of anatomic integrity and function of the cranial nerves during the removal of skull base tumors is one of the most challenging procedures in endoscopic endonasal surgery. It is possible to use intraoperative mapping and identification of...

Showing 25 to 36 of 221 entries