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Predictors of urinary polycyclic aromatic hydrocarbon metabolites in girls from the San Francisco Bay Area.

Environmental research

John EM, Koo J, Ingles SA, Keegan TH, Nguyen JT, Thomsen C, Terry MB, Santella RM, Nguyen K, Yan B.
PMID: 34896321
Environ Res. 2021 Dec 10;205:112534. doi: 10.1016/j.envres.2021.112534. Epub 2021 Dec 10.

BACKGROUND: Polycyclic aromatic hydrocarbon (PAH) exposures from tobacco smoke, automobile exhaust, grilled or smoked meat and other sources are widespread and are a public health concern, as many are classified as probable carcinogens and suspected endocrine-disrupting chemicals. PAH exposures...

Sox2 modulation increases naïve pluripotency plasticity.

iScience

Tremble KC, Stirparo GG, Bates LE, Maskalenka K, Stuart HT, Jones K, Andersson-Rolf A, Radzisheuskaya A, Koo BK, Bertone P, Silva JCR.
PMID: 33665571
iScience. 2021 Feb 06;24(3):102153. doi: 10.1016/j.isci.2021.102153. eCollection 2021 Mar 19.

Induced pluripotency provides a tool to explore mechanisms underlying establishment, maintenance, and differentiation of naive pluripotent stem cells (nPSCs). Here, we report that self-renewal of nPSCs requires minimal Sox2 expression (Sox2-low). Sox2-low nPSCs do not show impaired neuroectoderm specification...

Showing 1225 to 1226 of 1226 entries