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Characterization, pharmacokinetics, and pharmacodynamics of anti-Siglec-15 antibody and its potency for treating osteoporosis and as follow-up treatment after parathyroid hormone use.

Bone

Tsuda E, Fukuda C, Okada A, Karibe T, Hiruma Y, Takagi N, Isumi Y, Yamamoto T, Hasegawa T, Uehara S, Koide M, Udagawa N, Amizuka N, Kumakura S.
PMID: 34715394
Bone. 2021 Oct 27;155:116241. doi: 10.1016/j.bone.2021.116241. Epub 2021 Oct 27.

Recent studies have established the idea that Siglec-15 is involved in osteoclast differentiation and/or function, and it is anticipated that therapies suppressing Siglec-15 function can be used to treat bone diseases such as osteoporosis. We have produced rat monoclonal...

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Tsuda E, Fukuda C, Okada A, et al. Characterization, pharmacokinetics, and pharmacodynamics of anti-Siglec-15 antibody and its potency for treating osteoporosis and as follow-up treatment after parathyroid hormone use. Bone. 2021;155:116241doi: 10.1016/j.bone.2021.116241.
Tsuda, E., Fukuda, C., Okada, A., Karibe, T., Hiruma, Y., Takagi, N., Isumi, Y., Yamamoto, T., Hasegawa, T., Uehara, S., Koide, M., Udagawa, N., Amizuka, N., & Kumakura, S. (2021). Characterization, pharmacokinetics, and pharmacodynamics of anti-Siglec-15 antibody and its potency for treating osteoporosis and as follow-up treatment after parathyroid hormone use. Bone, 155116241. https://doi.org/10.1016/j.bone.2021.116241
Tsuda, Eisuke, et al. "Characterization, pharmacokinetics, and pharmacodynamics of anti-Siglec-15 antibody and its potency for treating osteoporosis and as follow-up treatment after parathyroid hormone use." Bone vol. 155 (2021): 116241. doi: https://doi.org/10.1016/j.bone.2021.116241
Tsuda E, Fukuda C, Okada A, Karibe T, Hiruma Y, Takagi N, Isumi Y, Yamamoto T, Hasegawa T, Uehara S, Koide M, Udagawa N, Amizuka N, Kumakura S. Characterization, pharmacokinetics, and pharmacodynamics of anti-Siglec-15 antibody and its potency for treating osteoporosis and as follow-up treatment after parathyroid hormone use. Bone. 2021 Oct 27;155:116241. doi: 10.1016/j.bone.2021.116241. Epub 2021 Oct 27. PMID: 34715394.
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The Development of Teachers' and Their Students' Social and Emotional Learning During the "Learning to Be Project"-Training Course in Five European Countries.

Frontiers in psychology

Berg M, Talvio M, Hietajärvi L, Benítez I, Cavioni V, Conte E, Cuadrado F, Ferreira M, Košir M, Martinsone B, Ornaghi V, Raudiene I, Šukyte D, Talić S, Lonka K.
PMID: 34484059
Front Psychol. 2021 Aug 13;12:705336. doi: 10.3389/fpsyg.2021.705336. eCollection 2021.

In recent years, the school curricula in many European countries have introduced social and emotional learning (SEL). This calls for the teachers to have SEL competencies. The present study evaluates teachers' and their students' readiness for SEL during an...

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Berg M, Talvio M, Hietajärvi L, et al. The Development of Teachers' and Their Students' Social and Emotional Learning During the "Learning to Be Project"-Training Course in Five European Countries. Front Psychol. 2021;12:705336doi: 10.3389/fpsyg.2021.705336.
Berg, M., Talvio, M., Hietajärvi, L., Benítez, I., Cavioni, V., Conte, E., Cuadrado, F., Ferreira, M., Košir, M., Martinsone, B., Ornaghi, V., Raudiene, I., Šukyte, D., Talić, S., & Lonka, K. (2021). The Development of Teachers' and Their Students' Social and Emotional Learning During the "Learning to Be Project"-Training Course in Five European Countries. Frontiers in psychology, 12705336. https://doi.org/10.3389/fpsyg.2021.705336
Berg, Minna, et al. "The Development of Teachers' and Their Students' Social and Emotional Learning During the "Learning to Be Project"-Training Course in Five European Countries." Frontiers in psychology vol. 12 (2021): 705336. doi: https://doi.org/10.3389/fpsyg.2021.705336
Berg M, Talvio M, Hietajärvi L, Benítez I, Cavioni V, Conte E, Cuadrado F, Ferreira M, Košir M, Martinsone B, Ornaghi V, Raudiene I, Šukyte D, Talić S, Lonka K. The Development of Teachers' and Their Students' Social and Emotional Learning During the "Learning to Be Project"-Training Course in Five European Countries. Front Psychol. 2021 Aug 13;12:705336. doi: 10.3389/fpsyg.2021.705336. eCollection 2021. PMID: 34484059; PMCID: PMC8414967.
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Trends in voluntary vaccination coverage in a Japanese city.

Pediatrics international : official journal of the Japan Pediatric Society

Hoshina T, Kawase M, Watanabe S, Shibahara J, Kojiro M, Miyake T, Sakaguchi Y, Kajiwara Y, Kusuhara K.
PMID: 33780596
Pediatr Int. 2021 Dec;63(12):1466-1471. doi: 10.1111/ped.14712. Epub 2021 Nov 08.

BACKGROUND: Large numbers of patients with diseases preventable by voluntary vaccines have been reported in Japan. However, it is difficult to analyze the impact of voluntary vaccination on disease prevention, as governments do not aggregate the number of recipients...

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Hoshina T, Kawase M, Watanabe S, et al. Trends in voluntary vaccination coverage in a Japanese city. Pediatr Int. 2021;63(12):1466-1471doi: 10.1111/ped.14712.
Hoshina, T., Kawase, M., Watanabe, S., Shibahara, J., Kojiro, M., Miyake, T., Sakaguchi, Y., Kajiwara, Y., & Kusuhara, K. (2021). Trends in voluntary vaccination coverage in a Japanese city. Pediatrics international : official journal of the Japan Pediatric Society, 63(12), 1466-1471. https://doi.org/10.1111/ped.14712
Hoshina, Takayuki, et al. "Trends in voluntary vaccination coverage in a Japanese city." Pediatrics international : official journal of the Japan Pediatric Society vol. 63,12 (2021): 1466-1471. doi: https://doi.org/10.1111/ped.14712
Hoshina T, Kawase M, Watanabe S, Shibahara J, Kojiro M, Miyake T, Sakaguchi Y, Kajiwara Y, Kusuhara K. Trends in voluntary vaccination coverage in a Japanese city. Pediatr Int. 2021 Dec;63(12):1466-1471. doi: 10.1111/ped.14712. Epub 2021 Nov 08. PMID: 33780596.
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Self-Assembly of a Pyridine-Based Amphiphile Complexed with Regioisomeric Dihydroxy Naphthalenes into Supramolecular Nanotubes with Different Inner Diameters.

Chemistry (Weinheim an der Bergstrasse, Germany)

Kameta N, Kogiso M.
PMID: 34296478
Chemistry. 2021 Sep 01;27(49):12566-12573. doi: 10.1002/chem.202101354. Epub 2021 Aug 04.

A pyridine-based amphiphile complexed with 1,5-, 1,6-, 2,6-, or 2,7-dihydroxy naphthalene self-assembled in water to form nanotubes with inner diameters of 46, 38, 24, 18, and 11 nm in which the naphthalene molecules formed J-type aggregates. In contrast, the...

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Kameta N, Kogiso M. Self-Assembly of a Pyridine-Based Amphiphile Complexed with Regioisomeric Dihydroxy Naphthalenes into Supramolecular Nanotubes with Different Inner Diameters. Chemistry. 2021;27(49):12566-12573doi: 10.1002/chem.202101354.
Kameta, N., & Kogiso, M. (2021). Self-Assembly of a Pyridine-Based Amphiphile Complexed with Regioisomeric Dihydroxy Naphthalenes into Supramolecular Nanotubes with Different Inner Diameters. Chemistry (Weinheim an der Bergstrasse, Germany), 27(49), 12566-12573. https://doi.org/10.1002/chem.202101354
Kameta, Naohiro, and Kogiso, Masaki. "Self-Assembly of a Pyridine-Based Amphiphile Complexed with Regioisomeric Dihydroxy Naphthalenes into Supramolecular Nanotubes with Different Inner Diameters." Chemistry (Weinheim an der Bergstrasse, Germany) vol. 27,49 (2021): 12566-12573. doi: https://doi.org/10.1002/chem.202101354
Kameta N, Kogiso M. Self-Assembly of a Pyridine-Based Amphiphile Complexed with Regioisomeric Dihydroxy Naphthalenes into Supramolecular Nanotubes with Different Inner Diameters. Chemistry. 2021 Sep 01;27(49):12566-12573. doi: 10.1002/chem.202101354. Epub 2021 Aug 04. PMID: 34296478.
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History-Driven Genetic Modification Design Technique Using a Domain-Specific Lexical Model for the Acceleration of DBTL Cycles for Microbial Cell Factories.

ACS synthetic biology

Nakazawa S, Imaichi O, Kogure T, Kubota T, Toyoda K, Suda M, Inui M, Ito K, Shirai T, Araki M.
PMID: 34351735
ACS Synth Biol. 2021 Sep 17;10(9):2308-2317. doi: 10.1021/acssynbio.1c00234. Epub 2021 Aug 05.

The development of microbes for conducting bioprocessing

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Nakazawa S, Imaichi O, Kogure T, et al. History-Driven Genetic Modification Design Technique Using a Domain-Specific Lexical Model for the Acceleration of DBTL Cycles for Microbial Cell Factories. ACS Synth Biol. 2021;10(9):2308-2317doi: 10.1021/acssynbio.1c00234.
Nakazawa, S., Imaichi, O., Kogure, T., Kubota, T., Toyoda, K., Suda, M., Inui, M., Ito, K., Shirai, T., & Araki, M. (2021). History-Driven Genetic Modification Design Technique Using a Domain-Specific Lexical Model for the Acceleration of DBTL Cycles for Microbial Cell Factories. ACS synthetic biology, 10(9), 2308-2317. https://doi.org/10.1021/acssynbio.1c00234
Nakazawa, Shiori, et al. "History-Driven Genetic Modification Design Technique Using a Domain-Specific Lexical Model for the Acceleration of DBTL Cycles for Microbial Cell Factories." ACS synthetic biology vol. 10,9 (2021): 2308-2317. doi: https://doi.org/10.1021/acssynbio.1c00234
Nakazawa S, Imaichi O, Kogure T, Kubota T, Toyoda K, Suda M, Inui M, Ito K, Shirai T, Araki M. History-Driven Genetic Modification Design Technique Using a Domain-Specific Lexical Model for the Acceleration of DBTL Cycles for Microbial Cell Factories. ACS Synth Biol. 2021 Sep 17;10(9):2308-2317. doi: 10.1021/acssynbio.1c00234. Epub 2021 Aug 05. PMID: 34351735.
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Phase-separated protein droplets of amyotrophic lateral sclerosis-associated p62/SQSTM1 mutants show reduced inner fluidity.

The Journal of biological chemistry

Faruk MO, Ichimura Y, Kageyama S, Komatsu-Hirota S, El-Gowily AH, Sou YS, Koike M, Noda NN, Komatsu M.
PMID: 34774801
J Biol Chem. 2021 Nov 12;297(6):101405. doi: 10.1016/j.jbc.2021.101405. Epub 2021 Nov 12.

Several amyotrophic lateral sclerosis (ALS)-related proteins such as FUS, TDP-43, and hnRNPA1 demonstrate liquid-liquid phase separation, and their disease-related mutations correlate with a transition of their liquid droplet form into aggregates. Missense mutations in SQSTM1/p62, which have been identified...

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Faruk MO, Ichimura Y, Kageyama S, et al. Phase-separated protein droplets of amyotrophic lateral sclerosis-associated p62/SQSTM1 mutants show reduced inner fluidity. J Biol Chem. 2021;297(6):101405doi: 10.1016/j.jbc.2021.101405.
Faruk, M. O., Ichimura, Y., Kageyama, S., Komatsu-Hirota, S., El-Gowily, A. H., Sou, Y. S., Koike, M., Noda, N. N., & Komatsu, M. (2021). Phase-separated protein droplets of amyotrophic lateral sclerosis-associated p62/SQSTM1 mutants show reduced inner fluidity. The Journal of biological chemistry, 297(6), 101405. https://doi.org/10.1016/j.jbc.2021.101405
Faruk, Mohammad Omar, et al. "Phase-separated protein droplets of amyotrophic lateral sclerosis-associated p62/SQSTM1 mutants show reduced inner fluidity." The Journal of biological chemistry vol. 297,6 (2021): 101405. doi: https://doi.org/10.1016/j.jbc.2021.101405
Faruk MO, Ichimura Y, Kageyama S, Komatsu-Hirota S, El-Gowily AH, Sou YS, Koike M, Noda NN, Komatsu M. Phase-separated protein droplets of amyotrophic lateral sclerosis-associated p62/SQSTM1 mutants show reduced inner fluidity. J Biol Chem. 2021 Nov 12;297(6):101405. doi: 10.1016/j.jbc.2021.101405. Epub 2021 Nov 12. PMID: 34774801.
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Showing 661 to 666 of 666 entries