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Showing 61 to 69 of 69 entries
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Comparison of the medical students' perceived self-efficacy and the evaluation of the observers and patients.

BMC medical education

Ammentorp J, Thomsen JL, Jarbøl DE, Holst R, Øvrehus AL, Kofoed PE.
PMID: 23565905
BMC Med Educ. 2013 Apr 08;13:49. doi: 10.1186/1472-6920-13-49.

BACKGROUND: The accuracy of self-assessment has been questioned in studies comparing physicians' self-assessments to observed assessments; however, none of these studies used self-efficacy as a method for self-assessment. The aim of the study was to investigate how medical students'...

Application of Lime ( Citrus aurantifolia ) Juice to Drinking Water and Food as a Cholera-Preventive Measure.

Journal of food protection

Dalsgaard A, Reichert P, Mortensen HF, Sandström A, Kofoed PE, Larsen JL, Mølbak K.
PMID: 31207773
J Food Prot. 1997 Nov;60(11):1329-1333. doi: 10.4315/0362-028X-60.11.1329.

The protective activity of lime juice against cholera was suggested in a recent case-control study from Guinea-Bissau, On the basis of these findings, we investigated the vibriocidal properties of juice from lime ( Citrus aurantifolia ) fruits added to...

Correction to: Health-related qualify of life, angina type and coronary artery disease in patients with stable chest pain.

Health and quality of life outcomes

Rieckmann N, Neumann K, Feger S, Ibes P, Napp A, Preuß D, Dreger H, Feuchtner G, Plank F, Suchánek V, Veselka J, Engstrøm T, Kofoed KF, Schröder S, Zelesny T, Gutberlet M, Woinke M, Maurovich-Horvat P, Merkely B, Donnelly P, Ball P, Dodd JD, Hensey M, Loi B, Saba L, Francone M, Mancone M, Berzina M, Erglis A, Vaitiekiene A, Zajanckauskiene L, Harań T, Suckiel MI, Faria R, Gama-Ribeiro V, Benedek I, Rodean I, Adjić F, Adjić NČ, Rodriguez-Palomares J, Del Blanco BG, Brooksbank K, Collison D, Davis G, Thwaite E, Knuuti J, Saraste A, Kępka C, Kruk M, Benedek T, Ratiu M, Neskovic AN, Vidakovic R, Diez I, Lecumberri I, Fisher M, Ruzsics B, Hollingworth W, Gutiérrez-Ibarluzea I, Dewey M, Müller-Nordhorn J.
PMID: 32600467
Health Qual Life Outcomes. 2020 Jun 29;18(1):205. doi: 10.1186/s12955-020-01443-8.

An amendment to this paper has been published and can be accessed via the original article.

Shigella ubiquitin ligase IpaH7.8 targets gasdermin D for degradation to prevent pyroptosis and enable infection.

Cell host & microbe

Luchetti G, Roncaioli JL, Chavez RA, Schubert AF, Kofoed EM, Reja R, Cheung TK, Liang Y, Webster JD, Lehoux I, Skippington E, Reeder J, Haley B, Tan MW, Rose CM, Newton K, Kayagaki N, Vance RE, Dixit VM.
PMID: 34492225
Cell Host Microbe. 2021 Oct 13;29(10):1521-1530.e10. doi: 10.1016/j.chom.2021.08.010. Epub 2021 Sep 06.

The pore-forming protein gasdermin D (GSDMD) executes lytic cell death called pyroptosis to eliminate the replicative niche of intracellular pathogens. Evolution favors pathogens that circumvent this host defense mechanism. Here, we show that the Shigella ubiquitin ligase IpaH7.8 functions...

Robot-Assisted Hybrid Esophagectomy Is Associated with a Shorter Length of Stay Compared to Conventional Transthoracic Esophagectomy: A Retrospective Study.

Minimally invasive surgery

Rolff HC, Ambrus RB, Belmouhand M, Achiam MP, Wegmann M, Siemsen M, Kofoed SC, Svendsen LB.
PMID: 29362674
Minim Invasive Surg. 2017;2017:6907896. doi: 10.1155/2017/6907896. Epub 2017 Dec 06.

AIM: To compare the peri- and postoperative data between a hybrid minimally invasive esophagectomy (HMIE) and the conventional Ivor Lewis esophagectomy.METHODS: Retrospective comparison of perioperative characteristics, postoperative complications, and survival between HMIE and Ivor Lewis esophagectomy.RESULTS: 216 patients were...

The effect of fatty diacid acylation of human PYY.

Scientific reports

Østergaard S, Paulsson JF, Kofoed J, Zosel F, Olsen J, Jeppesen CB, Spetzler J, Ynddal L, Schleiss LG, Christoffersen BØ, Raun K, Sensfuss U, Nielsen FS, Jørgensen R, Wulff BS.
PMID: 34707178
Sci Rep. 2021 Oct 27;11(1):21179. doi: 10.1038/s41598-021-00654-3.

Peptides are notoriously known to display very short in vivo half-lives often measured in minutes which in many cases greatly reduces or eliminates sufficient in vivo efficacy. To obtain long half-lives allowing for up to once-weekly dosing regimen, fatty...

Monitoring process-related impurities in biologics-host cell protein analysis.

Analytical and bioanalytical chemistry

Pilely K, Johansen MR, Lund RR, Kofoed T, Jørgensen TK, Skriver L, Mørtz E.
PMID: 34595561
Anal Bioanal Chem. 2021 Oct 01; doi: 10.1007/s00216-021-03648-2. Epub 2021 Oct 01.

During biologics development, manufacturers must demonstrate clearance of host cell impurities and contaminants to ensure drug purity, manufacturing process consistency, and patient safety. Host cell proteins (HCPs) are a major class of process-related impurities and require monitoring and documentation...

Transgene distribution and immune response after ultrasound delivery of rAAV9 and PHP.B to the brain in a mouse model of amyloidosis.

Molecular therapy. Methods & clinical development

Kofoed RH, Heinen S, Silburt J, Dubey S, Dibia CL, Maes M, Simpson EM, Hynynen K, Aubert I.
PMID: 34761053
Mol Ther Methods Clin Dev. 2021 Oct 08;23:390-405. doi: 10.1016/j.omtm.2021.10.001. eCollection 2021 Dec 10.

Efficient disease-modifying treatments for Alzheimer disease, the most common form of dementia, have yet to be established. Gene therapy has the potential to provide the long-term production of therapeutic in the brain following a single administration. However, the blood-brain...

Elevated lipoprotein(a) in mitral and aortic valve calcification and disease: The Copenhagen General Population Study.

Atherosclerosis

Kaltoft M, Sigvardsen PE, Afzal S, Langsted A, Fuchs A, Kühl JT, Køber L, Kamstrup PR, Kofoed KF, Nordestgaard BG.
PMID: 34903381
Atherosclerosis. 2021 Dec 03; doi: 10.1016/j.atherosclerosis.2021.11.029. Epub 2021 Dec 03.

BACKGROUND AND AIMS: We tested the hypotheses (i) that elevated lipoprotein(a) is causally associated with both mitral and aortic valve calcification and disease, and (ii) that aortic valve calcification mediates the effect of elevated lipoprotein(a) on aortic valve stenosis.METHODS:...

Showing 61 to 69 of 69 entries