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Managing Deviating EQA Results: A Survey to Assess the Corrective and Preventive Actions of Medical Laboratories Testing for Oncological Biomarkers.

Diagnostics (Basel, Switzerland)

Keppens C, Schuuring E, Dequeker EM.
PMID: 33080995
Diagnostics (Basel). 2020 Oct 18;10(10). doi: 10.3390/diagnostics10100837.

Laboratories testing predictive biomarkers in lung and colorectal cancer are advised to participate in external quality assessment (EQA) schemes. This study aimed to investigate which corrective actions were taken by laboratories if predetermined performance criteria were not met, to...

Comparison of Fasciocutaneous and Muscle-based Free Flaps for Soft Tissue Reconstruction of the Upper Extremity.

Plastic and reconstructive surgery. Global open

Koepple C, Kallenberger AK, Pollmann L, Hundeshagen G, Schmidt VJ, Kneser U, Hirche C.
PMID: 32537297
Plast Reconstr Surg Glob Open. 2019 Dec 31;7(12):e2543. doi: 10.1097/GOX.0000000000002543. eCollection 2019 Dec.

Soft tissue free flap reconstruction of upper extremities has proven to be reliable and essential for limb salvage and function. Nevertheless, comparative data regarding flap outcome are still lacking. The present study aimed to compare procedural features and individual...

Virtual Reality Augments Movement during Physical Therapy: A Pragmatic Randomized Trial.

American journal of physical medicine & rehabilitation

Hemphill S, Rodriguez S, Wang E, Koeppen K, Aitken-Young B, Jackson C, Simons L, Caruso TJ.
PMID: 33935153
Am J Phys Med Rehabil. 2021 Apr 30; doi: 10.1097/PHM.0000000000001779. Epub 2021 Apr 30.

OBJECTIVE: Virtual reality (VR) facilitates physical therapy (PT) via improved engagement. While shown to benefit specific patient populations, such as stroke patients, it is less established in otherwise healthy adults and children receiving outpatient PT. The primary objective was...

Deep brain stimulation (DBS) of anterior nucleus thalami (ANT) in female epilepsy patients during pregnancy and delivery: experience from two cases.

Epileptic disorders : international epilepsy journal with videotape

House PM, Herzer A, Lorenzi I, Niedernhöfer P, Voges B, Stodieck S, Westphal M, Schaper M, Koeppen JA, Hamel W.
PMID: 34612820
Epileptic Disord. 2021 Oct 05; doi: 10.1684/epd.2021.1330. Epub 2021 Oct 05.

No abstract available.

GAUGE-Annotated Microbial Transcriptomic Data Facilitate Parallel Mining and High-Throughput Reanalysis To Form Data-Driven Hypotheses.

mSystems

Li Z, Koeppen K, Holden VI, Neff SL, Cengher L, Demers EG, Mould DL, Stanton BA, Hampton TH.
PMID: 33758032
mSystems. 2021 Mar 23;6(2). doi: 10.1128/mSystems.01305-20.

The NCBI Gene Expression Omnibus (GEO) provides tools to query and download transcriptomic data. However, less than 4% of microbial experiments include the sample group annotations required to assess differential gene expression for high-throughput reanalysis, and data deposited after...

Decoding non-canonical mRNA decay by the endoplasmic-reticulum stress sensor IRE1α.

Nature communications

Le Thomas A, Ferri E, Marsters S, Harnoss JM, Lawrence DA, Zuazo-Gaztelu I, Modrusan Z, Chan S, Solon M, Chalouni C, Li W, Koeppen H, Rudolph J, Wang W, Wu TD, Walter P, Ashkenazi A.
PMID: 34911951
Nat Commun. 2021 Dec 15;12(1):7310. doi: 10.1038/s41467-021-27597-7.

Inositol requiring enzyme 1 (IRE1) mitigates endoplasmic-reticulum (ER) stress by orchestrating the unfolded-protein response (UPR). IRE1 spans the ER membrane, and signals through a cytosolic kinase-endoribonuclease module. The endoribonuclease generates the transcription factor XBP1s by intron excision between similar...

Decoding non-canonical mRNA decay by the endoplasmic-reticulum stress sensor IRE1α.

Nature communications

Le Thomas A, Ferri E, Marsters S, Harnoss JM, Lawrence DA, Zuazo-Gaztelu I, Modrusan Z, Chan S, Solon M, Chalouni C, Li W, Koeppen H, Rudolph J, Wang W, Wu TD, Walter P, Ashkenazi A.
PMID: 34911951
Nat Commun. 2021 Dec 15;12(1):7310. doi: 10.1038/s41467-021-27597-7.

Inositol requiring enzyme 1 (IRE1) mitigates endoplasmic-reticulum (ER) stress by orchestrating the unfolded-protein response (UPR). IRE1 spans the ER membrane, and signals through a cytosolic kinase-endoribonuclease module. The endoribonuclease generates the transcription factor XBP1s by intron excision between similar...

Clinical Course of Infection and Cross-Species Detection of Equine Parvovirus-Hepatitis.

Viruses

Reinecke B, Klöhn M, Brüggemann Y, Kinast V, Todt D, Stang A, Badenhorst M, Koeppel K, Guthrie A, Groner U, Puff C, de le Roi M, Baumgärtner W, Cavalleri JV, Steinmann E.
PMID: 34452320
Viruses. 2021 Jul 26;13(8). doi: 10.3390/v13081454.

Since its first discovery by Arnold Theiler in 1918, serum hepatitis also known as Theiler's disease has been reported worldwide, causing idiopathic acute hepatitis and liver failure in horses. Recent studies have suggested a novel parvovirus, named equine parvovirus...

Microenvironmental regulation of tumour immunity and response to immunotherapy.

The Journal of pathology

Kockx MM, McCleland M, Koeppen H.
PMID: 33846997
J Pathol. 2021 Jul;254(4):374-383. doi: 10.1002/path.5681. Epub 2021 May 19.

The confluence of immunology and oncology has led to a lot of uncertainty and questions about relevant biomarkers. Despite the complexity of the tumour microenvironment, most clinical studies have relied on a single-parameter immunohistochemical assay to prospectively select patients...

Measurement of the electric form factor of the neutron at Q2=0.5 and 1.0 GeV2/c2.

Physical review letters

Warren G, Wesselmann F, Zhu H, McKee P, Savvinov N, Zeier M, Aghalaryan A, Ahmidouch A, Arenhövel H, Asaturyan R, Ben-Dayan I, Bloch F, Boeglin W, Boillat B, Breuer H, Brower J, Carasco C, Carl M, Carlini R, Cha J, Chant N, Christy E, Cole L, Coman L, Coman M, Crabb D, Danagoulian S, Day D, Duek K, Dunne J, Elaasar M, Ent R, Farrell J, Fatemi R, Fawcett D, Fenker H, Forest T, Garrow K, Gasparian A, Goussev I, Gueye P, Harvey M, Hauger M, Herrera R, Hu B, Jaegle I, Jones M, Jourdan J, Keith C, Kelly J, Keppel C, Khandaker M, Klein A, Klimenko A, Kramer L, Krusche B, Kuhn S, Liang Y, Lichtenstadt J, Lindgren R, Liu J, Lung A, Mack D, Maclachlan G, Markowitz P, McNulty D, Meekins D, Mitchell J, Mkrtchyan H, Nasseripour R, Niculescu I, Normand K, Norum B, Opper A, Piasetzky E, Pierce J, Pitt M, Prok Y, Raue B, Reinhold J, Roche J, Rohe D, Rondon O, Sacker D, Sawatzky B, Seely M, Sick I, Simicevic N, Smith C, Smith G, Steinacher M, Stepanyan S, Stout J, Tadevosyan V, Tajima S, Tang L, Testa G, Trojer R, Vlahovic B, Vulcan B, Wang K, Wells S, Woehrle H, Wood S, Yan C, Yanay Y, Yuan L, Yun J, Zihlmann B.
PMID: 14995367
Phys Rev Lett. 2004 Jan 30;92(4):042301. doi: 10.1103/PhysRevLett.92.042301. Epub 2004 Jan 29.

The electric form factor of the neutron was determined from measurements of the d-->(e-->,e'n)p reaction for quasielastic kinematics. Polarized electrons were scattered off a polarized deuterated ammonia (15ND3) target in which the deuteron polarization was perpendicular to the momentum...

The molecular landscape of high-risk early breast cancer: comprehensive biomarker analysis of a phase III adjuvant population.

NPJ breast cancer

Wilson TR, Yu J, Lu X, Spoerke JM, Xiao Y, O'Brien C, Savage HM, Huw LY, Zou W, Koeppen H, Forrest WF, Fridlyand J, Fu L, Tam R, Schleifman EB, Sumiyoshi T, Molinero L, Hampton GM, O'Shaughnessy JA, Lackner MR.
PMID: 28721382
NPJ Breast Cancer. 2016 Jul 13;2:16022. doi: 10.1038/npjbcancer.2016.22. eCollection 2016.

Breast cancer is a heterogeneous disease and patients are managed clinically based on ER, PR, HER2 expression, and key risk factors. We sought to characterize the molecular landscape of high-risk breast cancer patients enrolled onto an adjuvant chemotherapy study...

Correction: Combined MEK and ERK inhibition overcomes therapy-mediated pathway reactivation in RAS mutant tumors.

PloS one

Merchant M, Moffat J, Schaefer G, Chan J, Wang X, Orr C, Cheng J, Hunsaker T, Shao L, Wang SJ, Wagle MC, Lin E, Haverty PM, Shahidi-Latham S, Ngu H, Solon M, Eastham-Anderson J, Koeppen H, Huang SA, Schwarz J, Belvin M, Kirouac D, Junttila MR.
PMID: 29370292
PLoS One. 2018 Jan 25;13(1):e0192059. doi: 10.1371/journal.pone.0192059. eCollection 2018.

[This corrects the article DOI: 10.1371/journal.pone.0185862.].

Showing 25 to 36 of 136 entries