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Showing 13 to 24 of 125 entries
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The Snake Study: Survey of National Attitudes and Knowledge in Envenomation.

Toxins

Braitberg G, Nimorakiotakis V, Yap CYL, Mukaro V, Welton R, Parker A, Knott J, Story D.
PMID: 34357954
Toxins (Basel). 2021 Jul 12;13(7). doi: 10.3390/toxins13070482.

Despite recent reviews of best practice for the treatment of Australian venomous bites and stings, there is controversy about some aspects of care, particularly the use of antivenom. Our aim was to understand current attitudes and practice in the...

An atomic Boltzmann machine capable of self-adaption.

Nature nanotechnology

Kiraly B, Knol EJ, van Weerdenburg WMJ, Kappen HJ, Khajetoorians AA.
PMID: 33526837
Nat Nanotechnol. 2021 Apr;16(4):414-420. doi: 10.1038/s41565-020-00838-4. Epub 2021 Feb 01.

The quest to implement machine learning algorithms in hardware has focused on combining various materials, each mimicking a computational primitive, to create device functionality. Ultimately, these piecewise approaches limit functionality and efficiency, while complicating scaling and on-chip learning, necessitating...

The genetics of circulating BDNF: towards understanding the role of BDNF in brain structure and function in middle and old ages.

Brain communications

Li S, Weinstein G, Zare H, Teumer A, Völker U, Friedrich N, Knol MJ, Satizabal CL, Petyuk VA, Adams HHH, Launer LJ, Bennett DA, De Jager PL, Grabe HJ, Ikram MA, Gudnason V, Yang Q, Seshadri S.
PMID: 33345186
Brain Commun. 2020 Oct 28;2(2):fcaa176. doi: 10.1093/braincomms/fcaa176. eCollection 2020.

Brain-derived neurotrophic factor (BDNF) plays an important role in brain development and function. Substantial amounts of BDNF are present in peripheral blood, and may serve as biomarkers for Alzheimer's disease incidence as well as targets for intervention to reduce...

Vaccine effectiveness against SARS-CoV-2 transmission and infections among household and other close contacts of confirmed cases, the Netherlands, February to May 2021.

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin

de Gier B, Andeweg S, Joosten R, Ter Schegget R, Smorenburg N, van de Kassteele J, Hahné SJ, van den Hof S, de Melker HE, Knol MJ.
PMID: 34355689
Euro Surveill. 2021 Aug;26(31). doi: 10.2807/1560-7917.ES.2021.26.31.2100640.

Several studies report high effectiveness of COVID-19 vaccines against SARS-CoV-2 infection and severe disease, however an important knowledge gap is the vaccine effectiveness against transmission (VET). We present estimates of the VET to household and other close contacts in...

Screening major trauma patients for prevalence of illicit drugs.

Drug and alcohol review

Knott J, Yap C, Mitra B, Gerdtz M, Daniel C, Braitberg G.
PMID: 34263497
Drug Alcohol Rev. 2022 Jan;41(1):285-292. doi: 10.1111/dar.13355. Epub 2021 Jul 15.

INTRODUCTION: Australasian emergency departments (ED) routinely test patient alcohol levels following major trauma, but assessment for illicit drugs is uncommon.METHODS: A prospective cross-sectional study of major motor-vehicle-related trauma patients attending both adult major trauma centres in Victoria, Australia. All...

Dietary sugar restriction reduces hepatic de novo lipogenesis in adolescent boys with fatty liver disease.

The Journal of clinical investigation

Cohen CC, Li KW, Alazraki AL, Beysen C, Carrier CA, Cleeton RL, Dandan M, Figueroa J, Knight-Scott J, Knott CJ, Newton KP, Nyangau EM, Sirlin CB, Ugalde-Nicalo PA, Welsh JA, Hellerstein MK, Schwimmer JB, Vos MB.
PMID: 34907907
J Clin Invest. 2021 Dec 15;131(24). doi: 10.1172/JCI150996.

BACKGROUNDHepatic de novo lipogenesis (DNL) is elevated in nonalcoholic fatty liver disease (NAFLD). Improvements in hepatic fat by dietary sugar reduction may be mediated by reduced DNL, but data are limited, especially in children. We examined the effects of...

Kinetic analysis of Cas12a and Cas13a RNA-Guided nucleases for development of improved CRISPR-Based diagnostics.

iScience

Nalefski EA, Patel N, Leung PJY, Islam Z, Kooistra RM, Parikh I, Marion E, Knott GJ, Doudna JA, Le Ny AM, Madan D.
PMID: 34505008
iScience. 2021 Aug 18;24(9):102996. doi: 10.1016/j.isci.2021.102996. eCollection 2021 Sep 24.

Bacterial CRISPR systems provide acquired immunity against invading nucleic acids by activating RNA-programmable RNases and DNases. Cas13a and Cas12a enzymes bound to CRISPR RNA (crRNA) recognize specific nucleic acid targets, initiating cleavage of the targets as well as non-target...

Association of low-frequency and rare coding variants with information processing speed.

Translational psychiatry

Bressler J, Davies G, Smith AV, Saba Y, Bis JC, Jian X, Hayward C, Yanek L, Smith JA, Mirza SS, Wang R, Adams HHH, Becker D, Boerwinkle E, Campbell A, Cox SR, Eiriksdottir G, Fawns-Ritchie C, Gottesman RF, Grove ML, Guo X, Hofer E, Kardia SLR, Knol MJ, Koini M, Lopez OL, Marioni RE, Nyquist P, Pattie A, Polasek O, Porteous DJ, Rudan I, Satizabal CL, Schmidt H, Schmidt R, Sidney S, Simino J, Smith BH, Turner ST, van der Lee SJ, Ware EB, Whitmer RA, Yaffe K, Yang Q, Zhao W, Gudnason V, Launer LJ, Fitzpatrick AL, Psaty BM, Fornage M, Arfan Ikram M, van Duijn CM, Seshadri S, Mosley TH, Deary IJ.
PMID: 34864818
Transl Psychiatry. 2021 Dec 04;11(1):613. doi: 10.1038/s41398-021-01736-6.

Measures of information processing speed vary between individuals and decline with age. Studies of aging twins suggest heritability may be as high as 67%. The Illumina HumanExome Bead Chip genotyping array was used to examine the association of rare...

Dietary sugar restriction reduces hepatic de novo lipogenesis in adolescent boys with fatty liver disease.

The Journal of clinical investigation

Cohen CC, Li KW, Alazraki AL, Beysen C, Carrier CA, Cleeton RL, Dandan M, Figueroa J, Knight-Scott J, Knott CJ, Newton KP, Nyangau EM, Sirlin CB, Ugalde-Nicalo PA, Welsh JA, Hellerstein MK, Schwimmer JB, Vos MB.
PMID: 34907907
J Clin Invest. 2021 Dec 15;131(24). doi: 10.1172/JCI150996.

BACKGROUNDHepatic de novo lipogenesis (DNL) is elevated in nonalcoholic fatty liver disease (NAFLD). Improvements in hepatic fat by dietary sugar reduction may be mediated by reduced DNL, but data are limited, especially in children. We examined the effects of...

Changes in Invasive Pneumococcal Disease Caused by .

Microorganisms

Bennett JC, Hetrich MK, Garcia Quesada M, Sinkevitch JN, Deloria Knoll M, Feikin DR, Zeger SL, Kagucia EW, Cohen AL, Ampofo K, Brandileone MC, Bruden D, Camilli R, Castilla J, Chan G, Cook H, Cornick JE, Dagan R, Dalby T, Danis K, de Miguel S, De Wals P, Desmet S, Georgakopoulou T, Gilkison C, Grgic-Vitek M, Hammitt LL, Hilty M, Ho PL, Jayasinghe S, Kellner JD, Kleynhans J, Knol MJ, Kozakova J, Kristinsson KG, Ladhani SN, MacDonald L, Mackenzie GA, Mad'arová L, McGeer A, Mereckiene J, Morfeldt E, Mungun T, Muñoz-Almagro C, Nuorti JP, Paragi M, Pilishvili T, Puentes R, Saha SK, Sahu Khan A, Savrasova L, Scott JA, Skoczyńska A, Suga S, van der Linden M, Verani JR, von Gottberg A, Winje BA, Yildirim I, Zerouali K, Hayford K.
PMID: 33801760
Microorganisms. 2021 Mar 27;9(4). doi: 10.3390/microorganisms9040696.

No abstract available.

Dietary sugar restriction reduces hepatic de novo lipogenesis in adolescent boys with fatty liver disease.

The Journal of clinical investigation

Cohen CC, Li KW, Alazraki AL, Beysen C, Carrier CA, Cleeton RL, Dandan M, Figueroa J, Knight-Scott J, Knott CJ, Newton KP, Nyangau EM, Sirlin CB, Ugalde-Nicalo PA, Welsh JA, Hellerstein MK, Schwimmer JB, Vos MB.
PMID: 34907907
J Clin Invest. 2021 Dec 15;131(24). doi: 10.1172/JCI150996.

BACKGROUNDHepatic de novo lipogenesis (DNL) is elevated in nonalcoholic fatty liver disease (NAFLD). Improvements in hepatic fat by dietary sugar reduction may be mediated by reduced DNL, but data are limited, especially in children. We examined the effects of...

Anisotropic Two-Dimensional Screening at the Surface of Black Phosphorus.

Physical review letters

Kiraly B, Knol EJ, Volckaert K, Biswas D, Rudenko AN, Prishchenko DA, Mazurenko VG, Katsnelson MI, Hofmann P, Wegner D, Khajetoorians AA.
PMID: 31809169
Phys Rev Lett. 2019 Nov 22;123(21):216403. doi: 10.1103/PhysRevLett.123.216403.

Electronic screening can have direct consequences for structural arrangements on the nanoscale, such as on the periodic ordering of adatoms on a surface. So far, such ordering phenomena have been explained in terms of isotropic screening of free electronlike...

Showing 13 to 24 of 125 entries