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Showing 925 to 936 of 955 entries
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A phase I/II trial of brentuximab vedotin plus rituximab as frontline therapy for patients with immunosuppression-associated CD30+ and/or EBV + lymphomas.

Leukemia & lymphoma

Pearse WB, Petrich AM, Gordon LI, Karmali R, Winter JN, Ma S, Kaplan JB, Behdad A, Klein A, Jovanovic B, Helenowski I, Smith SM, Evens AM, Pro B.
PMID: 34338127
Leuk Lymphoma. 2021 Dec;62(14):3493-3500. doi: 10.1080/10428194.2021.1957867. Epub 2021 Aug 02.

Treatment strategies for post-transplant lymphoproliferative disorders (PTLD) consist of response-adapted risk-stratified methods using immunosuppression reduction, immunotherapy, and chemotherapy. We investigated the efficacy of Brentuximab vedotin given concurrently with Rituximab (BV + R) once weekly for four weeks, followed by...

Taphonomic and spatial analyses from the Early Pleistocene site of Venta Micena 4 (Orce, Guadix-Baza Basin, southern Spain).

Scientific reports

Luzón C, Yravedra J, Courtenay LA, Saarinen J, Blain HA, DeMiguel D, Viranta S, Azanza B, Rodríguez-Alba JJ, Herranz-Rodrigo D, Serrano-Ramos A, Solano JA, Oms O, Agustí J, Fortelius M, Jiménez-Arenas JM.
PMID: 34234181
Sci Rep. 2021 Jul 07;11(1):13977. doi: 10.1038/s41598-021-93261-1.

Venta Micena is an area containing several palaeontological sites marking the beginning of the Calabrian stage (Early Pleistocene). The richness of the fossil accumulation including species of Asian, African and European origin, makes Venta Micena a key site for...

Highly Efficient Solution-Processed Organic Light-Emitting Diodes Containing a New Cross-linkable Hole Transport Material Blended with Commercial Hole Transport Materials.

ACS applied materials & interfaces

Ha H, Shim YJ, Lee DH, Park EY, Lee IH, Yoon SK, Suh MC.
PMID: 33909414
ACS Appl Mater Interfaces. 2021 May 12;13(18):21954-21963. doi: 10.1021/acsami.1c01835. Epub 2021 Apr 28.

A new small-molecular thermally cross-linkable material {[4-(9-phenyl-9

Retrospective Enhanced Bat Lyssavirus Surveillance in Germany between 2018-2020.

Viruses

Klein A, Calvelage S, Schlottau K, Hoffmann B, Eggerbauer E, Müller T, Freuling CM.
PMID: 34452403
Viruses. 2021 Aug 03;13(8). doi: 10.3390/v13081538.

Lyssaviruses are the causative agents for rabies, a zoonotic and fatal disease. Bats are the ancestral reservoir host for lyssaviruses, and at least three different lyssaviruses have been found in bats from Germany. Across Europe, novel lyssaviruses were identified...

Proteomic Identification and Meta-Analysis in .

Plants (Basel, Switzerland)

Klein A, Husselmann LHH, Williams A, Bell L, Cooper B, Ragar B, Tabb DL.
PMID: 33919777
Plants (Basel). 2021 Apr 14;10(4). doi: 10.3390/plants10040765.

While proteomics has demonstrated its value for model organisms and for organisms with mature genome sequence annotations, proteomics has been of less value in nonmodel organisms that are unaccompanied by genome sequence annotations. This project sought to determine the...

A Rare Germline HOXB13 Variant Contributes to Risk of Prostate Cancer in Men of African Ancestry.

European urology

Darst BF, Hughley R, Pfennig A, Hazra U, Fan C, Wan P, Sheng X, Xia L, Andrews C, Chen F, Berndt SI, Kote-Jarai Z, Govindasami K, Bensen JT, Ingles SA, Rybicki BA, Nemesure B, John EM, Fowke JH, Huff CD, Strom SS, Isaacs WB, Park JY, Zheng W, Ostrander EA, Walsh PC, Carpten J, Sellers TA, Yamoah K, Murphy AB, Sanderson M, Crawford DC, Gapstur SM, Bush WS, Aldrich MC, Cussenot O, Petrovics G, Cullen J, Neslund-Dudas C, Kittles RA, Xu J, Stern MC, Chokkalingam AP, Multigner L, Parent ME, Menegaux F, Cancel-Tassin G, Kibel AS, Klein EA, Goodman PJ, Stanford JL, Drake BF, Hu JJ, Clark PE, Blanchet P, Casey G, Hennis AJM, Lubwama A, Thompson IM, Leach RJ, Gundell SM, Pooler L, Mohler JL, Fontham ETH, Smith GJ, Taylor JA, Brureau L, Blot WJ, Biritwum R, Tay E, Truelove A, Niwa S, Tettey Y, Varma R, McKean-Cowdin R, Torres M, Jalloh M, Magueye Gueye S, Niang L, Ogunbiyi O, Oladimeji Idowu M, Popoola O, Adebiyi AO, Aisuodionoe-Shadrach OI, Nwegbu M, Adusei B, Mante S, Darkwa-Abrahams A, Yeboah ED, Mensah JE, Anthony Adjei A, Diop H, Cook MB, Chanock SJ, Watya S, Eeles RA, Chiang CWK, Lachance J, Rebbeck TR, Conti DV, Haiman CA.
PMID: 35031163
Eur Urol. 2022 Jan 11; doi: 10.1016/j.eururo.2021.12.023. Epub 2022 Jan 11.

A rare African ancestry-specific germline deletion variant in HOXB13 (X285K, rs77179853) was recently reported in Martinican men with early-onset prostate cancer. Given the role of HOXB13 germline variation in prostate cancer, we investigated the association between HOXB13 X285K and...

GAGrank: Software for Glycosaminoglycan Sequence Ranking Using a Bipartite Graph Model.

Molecular & cellular proteomics : MCP

Hogan JD, Wu J, Klein JA, Lin C, Carvalho L, Zaia J.
PMID: 33992776
Mol Cell Proteomics. 2021 May 14;20:100093. doi: 10.1016/j.mcpro.2021.100093. Epub 2021 May 14.

The sulfated glycosaminoglycans (GAGs) are long, linear polysaccharide chains that are typically found as the glycan portion of proteoglycans. These GAGs are characterized by repeating disaccharide units with variable sulfation and acetylation patterns along the chain. GAG length and...

25th Anniversary of Molecules-Recent Advances in Inorganic Chemistry.

Molecules (Basel, Switzerland)

Blom B, Ferrari E, Tangoulis V, Mayer CR, Klein A, Stoumpos CC.
PMID: 33946693
Molecules. 2021 Apr 29;26(9). doi: 10.3390/molecules26092589.

Celebrating the "25th Anniversary of Molecules" with a Special Issue dedicated to "Recent Advances in Inorganic Chemistry" strengthens the renewed role that inorganic chemistry, one of the oldest chemistry divisions, has lately earned thanks to cutting-edge perspectives and interdisciplinary...

Spatiotemporal Dynamics of Stemphylium Leaf Blight and Potential Inoculum Sources in New York Onion Fields.

Plant disease

Hay F, Heck DW, Klein A, Sharma S, Hoepting CA, Pethybridge SJ.
PMID: 34798786
Plant Dis. 2021 Nov 19; doi: 10.1094/PDIS-07-21-1587-RE. Epub 2021 Nov 19.

Stemphylium leaf blight (SLB) caused by

Cardiac resynchronization therapy with- or without defibrillator. Estimating the risk of arrhythmic death or assessing the likelihood of non-arrhythmic mortality?.

International journal of cardiology

Klein HU.
PMID: 33582197
Int J Cardiol. 2021 May 01;330:82-83. doi: 10.1016/j.ijcard.2021.02.024. Epub 2021 Feb 11.

No abstract available.

Use of a 2 Dimensional Vessel Navigator Roadmap Decreases Patient Radiation Dose Compared to Standard 3D Mapping for Fenestrated Endovascular Aneurysm Repair.

Annals of vascular surgery

Klein A, Guild J, Xi Y, Chamseddin K, Shih M, Siah M, Timaran C, Kirkwood M.
PMID: 34748947
Ann Vasc Surg. 2021 Nov 05; doi: 10.1016/j.avsg.2021.08.042. Epub 2021 Nov 05.

OBJECTIVE: For fenestrated endovascular aneurysm repair (FEVAR), the implementation of the VesselNavigator (Philips Healthcare, Best, The Netherlands) to provide a 3-dimensional vessel roadmap has been shown to reduce patient radiation exposure. Unfortunately, FEVAR radiation doses remain substantial despite utilization...

Convergent evolution of bacterial ceramide synthesis.

Nature chemical biology

Stankeviciute G, Tang P, Ashley B, Chamberlain JD, Hansen MEB, Coleman A, D'Emilia R, Fu L, Mohan EC, Nguyen H, Guan Z, Campopiano DJ, Klein EA.
PMID: 34969973
Nat Chem Biol. 2021 Dec 30; doi: 10.1038/s41589-021-00948-7. Epub 2021 Dec 30.

The bacterial domain produces numerous types of sphingolipids with various physiological functions. In the human microbiome, commensal and pathogenic bacteria use these lipids to modulate the host inflammatory system. Despite their growing importance, their biosynthetic pathway remains undefined since...

Showing 925 to 936 of 955 entries