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Showing 13 to 24 of 1563 entries
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Loss of cystic fibrosis transmembrane conductance regulator impairs lung endothelial cell barrier function and increases susceptibility to microvascular damage from cigarette smoke.

Pulmonary circulation

Brown MB, Hunt WR, Noe JE, Rush NI, Schweitzer KS, Leece TC, Moldobaeva A, Wagner EM, Dudek SM, Poirier C, Presson RG, Gulbins E, Petrache I.
PMID: 25006445
Pulm Circ. 2014 Jun;4(2):260-8. doi: 10.1086/675989.

Abnormal lung microvascular endothelial vascular barrier function may contribute to pulmonary inflammation, such as that occurring during inhalation of cigarette smoke (CS). Cystic fibrosis transmembrane conductance regulator (CFTR), an anion channel expressed in both epithelial and endothelial cells, regulates...

Discontinuities Between Health Technology Assessment (HTA) and Health Care Service Objectives of the NHS.

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research

Brazier PJ, Durand A, Tierney R, Kelly S.
PMID: 27201237
Value Health. 2014 Nov;17(7):A450. doi: 10.1016/j.jval.2014.08.1210. Epub 2014 Oct 26.

No abstract available.

The efficacy of an extended scope physiotherapy clinic in paediatric orthopaedics.

Journal of children's orthopaedics

O Mir M, Cooney C, O'Sullivan C, Blake C, Kelly P, Kiely P, Noel J, Moore D.
PMID: 27039314
J Child Orthop. 2016 Apr;10(2):169-75. doi: 10.1007/s11832-016-0725-9. Epub 2016 Apr 02.

BACKGROUND: The demand for paediatric orthopaedic care is growing, and providing the service required is an increasingly challenging task. Physiotherapist-led triage clinics are utilised in adult orthopaedics to enable the provision of care to patients who may not require...

Co-production of 11α-hydroxyprogesterone and ethanol using recombinant yeast expressing fungal steroid hydroxylases.

Biotechnology for biofuels

Hull CM, Warrilow AGS, Rolley NJ, Price CL, Donnison IS, Kelly DE, Kelly SL.
PMID: 29021826
Biotechnol Biofuels. 2017 Sep 29;10:226. doi: 10.1186/s13068-017-0904-z. eCollection 2017.

BACKGROUND: Bioethanol production from sustainable sources of biomass that limit effect on food production are needed and in a biorefinery approach co-products are desirable, obtained from both the plant material and from the microbial biomass. Fungal biotransformation of steroids...

Ligand uptake in Mycobacterium tuberculosis truncated hemoglobins is controlled by both internal tunnels and active site water molecules.

F1000Research

Boron I, Bustamante JP, Davidge KS, Singh S, Bowman LA, Tinajero-Trejo M, Carballal S, Radi R, Poole RK, Dikshit K, Estrin DA, Marti MA, Boechi L.
PMID: 26478812
F1000Res. 2015 Jan 23;4:22. doi: 10.12688/f1000research.5921.1. eCollection 2015.

Mycobacterium tuberculosis, the causative agent of human tuberculosis, has two proteins belonging to the truncated hemoglobin (trHb) family. Mt-trHbN presents well-defined internal hydrophobic tunnels that allow O 2 and (•)NO to migrate easily from the solvent to the active...

DVT presentations to an Emergency Department: A study of guideline based care and decision making.

Irish medical journal

Lillis DA, Lloyd C, Kelada S, O'Kelly P, Kelly S, Gilligan P.
PMID: 27685687
Ir Med J. 2016 Feb 19;109(2):354.

Pre-test probability scoring and blood tests for deep venous thrombosis (DVT) assessment are sensitive but not specific leading to increased demands on radiology services. 385 patients presenting to an Emergency Department with suspected DVT were studied to explore our...

Isolation of Uranyl Dicyanamide Complexes from N-Donor Ionic Liquids.

Inorganic chemistry

Kelley SP, Rogers RD.
PMID: 26479078
Inorg Chem. 2015 Nov 02;54(21):10323-34. doi: 10.1021/acs.inorgchem.5b01699. Epub 2015 Oct 19.

An ionic liquid (IL) approach for soft-donor f-element chemistry has been demonstrated by the isolation of several new uranyl dicyanamide complexes through reactions of UO2(NO3)2·6H2O with dicyanamide ([N(CN)2](-))-containing ILs. The [N(CN)2](-) ions are able to rapidly substitute uranium's O-donor...

Turn It Off: An Action Research Study of Top Management Influence on Energy Conservation in the Workplace.

Frontiers in psychology

Russell SV, Evans A, Fielding KS, Hill C.
PMID: 27047417
Front Psychol. 2016 Mar 21;7:389. doi: 10.3389/fpsyg.2016.00389. eCollection 2016.

This paper reports the results of an intervention study that aimed to encourage workplace energy conservation behavior by office-based employees. Taking a co-production approach we worked with the participating organization to design and implement an intervention that used the...

Very-Brief, Web-Based Interventions for Reducing Alcohol Use and Related Problems among College Students: A Review.

Frontiers in psychiatry

Leeman RF, Perez E, Nogueira C, DeMartini KS.
PMID: 26441690
Front Psychiatry. 2015 Sep 28;6:129. doi: 10.3389/fpsyt.2015.00129. eCollection 2015.

Very-brief, web-based alcohol interventions have great potential due to their convenience, ease of dissemination, and college students' stated preference for this intervention modality. To address the efficacy of these interventions, we conducted a review of the literature to identify...

Allergen immunotherapy for the treatment of allergic rhinitis and/or asthma: an umbrella review.

CMAJ open

Elliott J, Kelly SE, Johnston A, Skidmore B, Gomes T, Wells GA.
PMID: 28495938
CMAJ Open. 2017 May 10;5(2):E373-E385. doi: 10.9778/cmajo.20160066.

BACKGROUND: Allergic rhinitis and asthma are important public health concerns, yet there is no consensus about the benefits and harms of allergen-specific immunotherapy to treat these conditions. We performed an umbrella review of systematic reviews summarizing the current evidence...

Understanding the mechanisms underpinning health inequalities: lessons from economics.

Global health promotion

Kelly MP.
PMID: 27353317
Glob Health Promot. 2016 Jun;23(2):3-5. doi: 10.1177/1757975916647676.

No abstract available.

A novel approach to the repair of urethrocutaneous fistulae arising after abdominoperineal anorectal resection.

Canadian Urological Association journal = Journal de l'Association des urologues du Canada

Yassein A, Dason S, Davies T, Kelly S.
PMID: 26834897
Can Urol Assoc J. 2015 Nov-Dec;9(11):E879-81. doi: 10.5489/cuaj.2938. Epub 2015 Dec 14.

This case report describes a novel approach to the repair of perineal urethrocutaneous fistulae (UCF) after abdominoperineal resection (APR). A 62-year-old patient developed a UCF after an APR for rectal cancer complicated by perineal abscess formation. The patient presented...

Showing 13 to 24 of 1563 entries