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Showing 181 to 182 of 182 entries
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The finding and researching algorithm for potentially oscillating enzymatic systems.

Vavilovskii zhurnal genetiki i selektsii

Lakhova TN, Kazantsev FV, Lashin SA, Matushkin YG.
PMID: 34901728
Vavilovskii Zhurnal Genet Selektsii. 2021 May;25(3):318-330. doi: 10.18699/VJ21.035.

Many processes in living organisms are subject to periodic oscillations at different hierarchical levels of their organization: from molecular-genetic to population and ecological. Oscillatory processes are responsible for cell cycles in both prokaryotes and eukaryotes, for circadian rhythms, for...

Constraints on error rate revealed by computational study of G•U tautomerization in translation.

Nucleic acids research

Kazantsev A, Ignatova Z.
PMID: 34669948
Nucleic Acids Res. 2021 Nov 18;49(20):11823-11833. doi: 10.1093/nar/gkab947.

In translation, G•U mismatch in codon-anticodon decoding is an error hotspot likely due to transition of G•U from wobble (wb) to Watson-Crick (WC) geometry, which is governed by keto/enol tautomerization (wb-WC reaction). Yet, effects of the ribosome on the...

Showing 181 to 182 of 182 entries