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Showing 13 to 24 of 643 entries
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Decreased SIRT1 expression and LKB1 phosphorylation occur with long-term high-fat diet feeding, in addition to AMPK phosphorylation impairment in the early phase.

Obesity research & clinical practice

Yoneda M, Guo Y, Ono H, Nakatsu Y, Zhang J, Cui X, Iwashita M, Kumamoto S, Tsuchiya Y, Sakoda H, Fujishiro M, Kushiyama A, Koketsu Y, Kikuchi T, Kamata H, Nishimura F, Asano T.
PMID: 24345663
Obes Res Clin Pract. 2010 Jul-Sep;4(3):e163-246. doi: 10.1016/j.orcp.2010.02.002.

AIMS: Energy sensing systems including AMPK and SIRT1 play important roles in the regulation of hepatic gluconeogenesis and fatty acid oxidation. In this study, we investigated how hepatic LKB1-AMPK signaling and SIRT1 expression are altered after 2 or 8...

Widespread Expression of Erythropoietin Receptor in Brain and Its Induction by Injury.

Molecular medicine (Cambridge, Mass.)

Ott C, Martens H, Hassouna I, Oliveira B, Erck C, Zafeiriou MP, Peteri UK, Hesse D, Gerhart S, Altas B, Kolbow T, Stadler H, Kawabe H, Zimmermann WH, Nave KA, Schulz-Schaeffer W, Jahn O, Ehrenreich H.
PMID: 26349059
Mol Med. 2015 Dec;21(1):803-815. doi: 10.2119/molmed.2015.00192. Epub 2015 Sep 01.

Erythropoietin (EPO) exerts potent neuroprotective, neuroregenerative and procognitive functions. However, unequivocal demonstration of erythropoietin receptor (EPOR) expression in brain cells has remained difficult since previously available anti-EPOR antibodies (EPOR-AB) were unspecific. We report here a new, highly specific, polyclonal...

Clinical outcomes of sigmoid colon volvulus: identification of the factors associated with successful endoscopic detorsion.

Intestinal research

Iida T, Nakagaki S, Satoh S, Shimizu H, Kaneto H, Nakase H.
PMID: 28522952
Intest Res. 2017 Apr;15(2):215-220. doi: 10.5217/ir.2017.15.2.215. Epub 2017 Apr 27.

BACKGROUND/AIMS: Although multiple treatment options exist for the management of sigmoid colon volvulus, no study has examined the factors associated with successful endoscopic detorsion. This study aimed to examine the clinical course of patients with sigmoid colon volvulus and...

Translational regulation of the expression of the ubiquitin E3 ligase Nedd4-1 by mTORC1-dependent signaling.

Communicative & integrative biology

Hsia HE, Kawabe H.
PMID: 26479408
Commun Integr Biol. 2015 Aug 07;8(4):e1017161. doi: 10.1080/19420889.2015.1017161. eCollection 2015.

We found recently that mTORC1 regulates the biosynthesis of the ubiquitin E3 ligase Nedd4-1, but not the close homolog Nedd4-2. This regulatory process plays a key role in promoting neurite growth in neurons of the mammalian central nervous system....

Strawberry milk-like blood in a subject with diabetic lipemia: dramatic change to transparent color after insulin therapy.

SpringerPlus

Obata A, Kamei S, Okauchi S, Kimura T, Hirukawa H, Tanabe A, Kinoshita T, Kohara K, Tatsumi F, Shimoda M, Nakanishi S, Mune T, Kaku K, Kaneto H.
PMID: 27652072
Springerplus. 2016 Sep 07;5(1):1499. doi: 10.1186/s40064-016-3202-5. eCollection 2016.

INTRODUCTION: It is known that chylomicronemia is caused by several pathologies and is classified as primary and secondary chylomicronemia. Since hypertriglycemia is associated with an increased risk of cardiovascular disease and severe pancreatitis, it is very important to make...

Pseudoaldosteronism induced by Yokukansan in an elderly Japanese type 2 diabetic patient with Alzheimer's disease.

Journal of diabetes investigation

Kamei S, Kaneto H, Irie S, Kinoshita T, Tanabe A, Hirukawa H, Tatsumi F, Shimoda M, Kohara K, Mune T, Kaku K.
PMID: 26221529
J Diabetes Investig. 2015 Jul;6(4):487-8. doi: 10.1111/jdi.12297. Epub 2015 Jul 02.

No abstract available.

Hepatic resection of hepatocellular carcinoma after proton beam therapy: A case report.

Hepatology research : the official journal of the Japan Society of Hepatology

Kinjo N, Ikeda Y, Taguchi K, Sugimoto R, Maehara S, Tsujita E, Kawano H, Yamaguchi S, Egashira A, Minami K, Yamamoto M, Morita M, Toh Y, Okamura T.
PMID: 26286377
Hepatol Res. 2016 Mar;46(5):483-8. doi: 10.1111/hepr.12576. Epub 2015 Oct 08.

Despite the widespread use of proton beam therapy (PBT) as locoregional therapy, there is currently a lack of histological evidence about the therapeutic effect of PBT for hepatocellular carcinoma (HCC). We present a case of hepatectomy and histological examination...

HSV-2-related hemophagocytic lymphohistiocytosis in a fingolimod-treated patient with MS.

Neurology(R) neuroimmunology & neuroinflammation

Ikumi K, Ando T, Katano H, Katsuno M, Sakai Y, Yoshida M, Saida T, Kimura H, Sobue G.
PMID: 27308307
Neurol Neuroimmunol Neuroinflamm. 2016 Jun 07;3(4):e247. doi: 10.1212/NXI.0000000000000247. eCollection 2016 Aug.

No abstract available.

[Effects of a novel method of anesthesia combining propofol and volatile anesthesia on the incidence of postoperative nausea and vomiting in patients undergoing laparoscopic gynecological surgery].

Revista brasileira de anestesiologia

Kawano H, Ohshita N, Katome K, Kadota T, Kinoshita M, Matsuoka Y, Tsutsumi YM, Kawahito S, Tanaka K, Oshita S.
PMID: 25896644
Rev Bras Anestesiol. 2016 Jan-Feb;66(1):12-8. doi: 10.1016/j.bjan.2014.07.006. Epub 2015 Apr 17.

BACKGROUND: We investigated the effects of a novel method of anesthesia combining propofol and volatile anesthesia on the incidence of postoperative nausea and vomiting in patients undergoing laparoscopic gynecological surgery.METHODS: Patients were randomly divided into three groups: those maintained...

[Leadership development program for student nurses (1)].

Kango tenbo. The Japanese journal of nursing science

Kamata H, Ichinohe T.
PMID: 6556424
Kango Tenbo. 1983 Aug;8(8):77-81.

No abstract available.

A Convenient Method for the Preparation of N(2)-Ethylguanine Nucleosides and Nucleotides.

The Journal of organic chemistry

Sako M, Kawada H, Hirota K.
PMID: 11674649
J Org Chem. 1999 Jul 23;64(15):5719-5721. doi: 10.1021/jo990500e.

No abstract available.

Development of anisotropic structure in the Earth's lower mantle by solid-state convection.

Nature

McNamara AK, van Keken PE, Karato S.
PMID: 11907574
Nature. 2002 Mar 21;416(6878):310-4. doi: 10.1038/416310a.

Seismological observations reveal highly anisotropic patches at the bottom of the Earth's lower mantle, whereas the bulk of the mantle has been observed to be largely isotropic. These patches have been interpreted to correspond to areas where subduction has...

Showing 13 to 24 of 643 entries