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Showing 1549 to 1558 of 1558 entries
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KEGG mapping tools for uncovering hidden features in biological data.

Protein science : a publication of the Protein Society

Kanehisa M, Sato Y, Kawashima M.
PMID: 34423492
Protein Sci. 2021 Aug 23; doi: 10.1002/pro.4172. Epub 2021 Aug 23.

In contrast to artificial intelligence and machine learning approaches, KEGG (https://www.kegg.jp) has relied on human intelligence to develop "models" of biological systems, especially in the form of KEGG pathway maps that are manually created by capturing knowledge from published...

Nemolizumab plus topical agents in patients with atopic dermatitis (AD) and moderate-to-severe pruritus provide improvement in pruritus and signs of AD for up to 68 weeks: results from two phase III, long-term studies.

The British journal of dermatology

Kabashima K, Matsumura T, Komazaki H, Kawashima M.
PMID: 34726262
Br J Dermatol. 2021 Nov 02; doi: 10.1111/bjd.20873. Epub 2021 Nov 02.

BACKGROUND: Interleukin (IL)-31 affects the inflammatory response, is involved in epidermal barrier disruption in atopic dermatitis (AD) and plays a key role in pruritus. Nemolizumab, a humanized monoclonal antibody against IL-31 receptor A, reduced pruritus in patients with AD...

Two distinct subsets of LDGs (low density granulocytes) in ANCA-associated vasculitis.

Modern rheumatology

Endo A, Komagata Y, Yamagishi K, Kawashima S, Arimura Y, Kaname S.
PMID: 33896353
Mod Rheumatol. 2021 Aug 31;1-10. doi: 10.1080/14397595.2021.1918883. Epub 2021 Aug 31.

OBJECTIVES AND METHODS: Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is an autoimmune disorder that causes vasculitis in small blood vessels throughout the body. Low-density granulocytes (LDGs) in autoimmune diseases, such as SLE and AAV, might play a critical role...

Time Transient of Calcium and Phosphate Ion Adsorption by Rutile Crystal Facets in Hanks' Solution Characterized by XPS.

Langmuir : the ACS journal of surfaces and colloids

Hiji A, Hanawa T, Yokoi T, Chen P, Ashida M, Kawashita M.
PMID: 33749278
Langmuir. 2021 Mar 30;37(12):3597-3604. doi: 10.1021/acs.langmuir.0c03540. Epub 2021 Mar 22.

For the elucidation of the mechanism of calcium phosphate formation on commercially pure titanium (CP Ti) in the human body, rutile TiO

Outcomes of pediatric anterior cruciate ligament reconstructions in patients with and without bucket handle meniscus repairs.

Journal of pediatric orthopedics. Part B

Kawashima I, Kawai R, Tsukahara T, Hiraiwa H, Ishizuka S, Kusaka Y, Imagama S.
PMID: 33720076
J Pediatr Orthop B. 2021 Mar 08; doi: 10.1097/BPB.0000000000000857. Epub 2021 Mar 08.

To report the outcomes of concomitant bucket handle meniscal tear (BHMT) repair and anterior cruciate ligament (ACL) reconstruction and to compare the outcomes with those after isolated ACL reconstruction in patients aged ≤16 years. Patients in our database from...

Current status of the diagnosis of chronic pancreatitis by ultrasonographic elastography.

The Korean journal of internal medicine

Nakaoka K, Hashimoto S, Miyahara R, Kawashima H, Ohno E, Ishikawa T, Kuwahara T, Tanaka H, Hirooka Y.
PMID: 34902894
Korean J Intern Med. 2021 Dec 15; doi: 10.3904/kjim.2021.252. Epub 2021 Dec 15.

Chronic pancreatitis (CP) is pathologically characterized by the loss of exocrine pancreatic parenchyma, irregular fibrosis, cellular infiltration, and ductal abnormalities. Diagnosing CP objectively is difficult because standard diagnostic criteria are insufficient. The change of parenchymal hardness is the key...

Association Between .

Frontiers in psychiatry

Komatsu H, Takeuchi H, Ono C, Yu Z, Kikuchi Y, Kakuto Y, Funakoshi S, Ono T, Kawashima R, Taki Y, Tomita H.
PMID: 33762978
Front Psychiatry. 2021 Mar 08;12:631475. doi: 10.3389/fpsyt.2021.631475. eCollection 2021.

Recent evidence has indicated that the disruption of oligodendrocytes may be involved in the pathogenesis of depression. Genetic factors are likely to affect trait factors, such as characteristics, rather than state factors, such as depressive symptoms. Previously, a negative...

Acute Coronary and Cerebral Emboli From a Pedunculated Ascending Aorta Thrombus.

JACC. Case reports

Shoda M, Yamamoto H, Kawashima M, Kondo T, Murakami H, Kawai H, Takaya T.
PMID: 34401758
JACC Case Rep. 2021 Aug 04;3(9):1194-1199. doi: 10.1016/j.jaccas.2021.04.031. eCollection 2021 Aug 04.

Hyperprolactinemia is a risk factor for thrombus formation. We present a rare case of a mobile ascending aorta thrombus leading to acute myocardial infarction and cerebral infarction in a patient with idiopathic hyperprolactinemia. (

Comprehensive expressional analysis of chemosensitivity-related markers in large cell neuroendocrine carcinoma of the lung.

Thoracic cancer

Ohtaki Y, Kaira K, Yajima T, Erkhem-Ochir B, Kawashima O, Kamiyoshihara M, Igai H, Onozato R, Ibe T, Kosaka T, Nakazawa S, Nagashima T, Oyama T, Shirabe K.
PMID: 34453496
Thorac Cancer. 2021 Oct;12(20):2666-2679. doi: 10.1111/1759-7714.14102. Epub 2021 Aug 28.

OBJECTIVES: Various drug-sensitivity markers have been reported to be associated with tumor progression and chemotherapy resistance. Detailed expression profiles of sensitivity markers for cytotoxic chemotherapy in pulmonary large cell neuroendocrine carcinoma (LCNEC) remain unclear. Herein, we aimed to clarify...

Basal cell carcinoma on the ventral site of the finger with an intronic deletion of SUFU gene.

Journal of the European Academy of Dermatology and Venereology : JEADV

Takata M, Komori T, Ishida Y, Fujimoto M, Ogawa S, Kabashima K.
PMID: 34553799
J Eur Acad Dermatol Venereol. 2022 Feb;36(2):e128-e130. doi: 10.1111/jdv.17694. Epub 2021 Sep 30.

No abstract available.

Showing 1549 to 1558 of 1558 entries