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Showing 13 to 24 of 1730 entries
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Practical Liposomal Formulation for Taxanes with Polyethoxylated Castor Oil and Ethanol with Complete Encapsulation Efficiency and High Loading Efficiency.

Nanomaterials (Basel, Switzerland)

Shigehiro T, Masuda J, Saito S, Khayrani AC, Jinno K, Seno A, Vaidyanath A, Mizutani A, Kasai T, Murakami H, Satoh A, Ito T, Hamada H, Seno Y, Mandai T, Seno M.
PMID: 28946623
Nanomaterials (Basel). 2017 Sep 23;7(10). doi: 10.3390/nano7100290.

Taxanes including paclitaxel and docetaxel are effective anticancer agents preferably sufficient for liposomal drug delivery. However, the encapsulation of these drugs with effective amounts into conventional liposomes is difficult due to their high hydrophobicity. Therefore, an effective encapsulation strategy...

Establishment of Immortalized Human Hepatocytes by Introduction of HPV16 E6/E7 and hTERT as Cell Sources for Liver Cell-Based Therapy.

Cell transplantation

Tsuruga Y, Kiyono T, Matsushita M, Takahashi T, Kasai H, Todo S.
PMID: 28863749
Cell Transplant. 2008 Sep;17(9):1083-1094. doi: 10.3727/096368908786991542.

For future cell-based therapies for liver diseases, the shortage of cell sources must be resolved. Immortalized human hepatocytes are expected to be among the new sources. In addition to telomerase activation by the introduction of human telomerase reverse transcriptase...

Structured line illumination Raman microscopy.

Nature communications

Watanabe K, Palonpon AF, Smith NI, Chiu LD, Kasai A, Hashimoto H, Kawata S, Fujita K.
PMID: 26626144
Nat Commun. 2015 Dec 02;6:10095. doi: 10.1038/ncomms10095.

In the last couple of decades, the spatial resolution in optical microscopy has increased to unprecedented levels by exploiting the fluorescence properties of the probe. At about the same time, Raman imaging techniques have emerged as a way to...

Effect of training in hypoxia on repeated sprint performance in female athletes.

SpringerPlus

Kasai N, Mizuno S, Ishimoto S, Sakamoto E, Maruta M, Goto K.
PMID: 26155449
Springerplus. 2015 Jul 02;4:310. doi: 10.1186/s40064-015-1041-4. eCollection 2015.

BACKGROUND: This study determined the effect of repeated sprint training in hypoxia (RSH) in female athletes.METHODS: Thirty-two college female athletes performed repeated cycling sprints of two sets of 10 × 7-s sprints with a 30-s rest between sprints twice...

9-Oxooctadeca-10,12-dienoic Acids as Acetyl-CoA Carboxylase Inhibitors from Red Pepper (Capsicum annuum L.).

Bioscience, biotechnology, and biochemistry

Watanebe J, Kawabata J, Kasai T.
PMID: 27393256
Biosci Biotechnol Biochem. 1999;63(3):489-93. doi: 10.1271/bbb.63.489.

A methanol extract of red pepper showed potent acetyl-CoA carboxylase inhibitory activity. The active principles were isolated and identified as (E, E)- and (E, Z)-9-oxooctadeca-10,12-dienoic acids by instrumental analyses. The IC50 values of the compounds were 1.4×10(-6) and 1.5×10(-6)...

120 Gbit/s injection-locked homodyne coherent transmission of polarization-multiplexed 64 QAM signals over 150 km.

Optics express

Wang Y, Kasai K, Yoshida M, Nakazawa M.
PMID: 25607079
Opt Express. 2014 Dec 15;22(25):31310-6. doi: 10.1364/OE.22.031310.

We describe an injection-locked 64 QAM homodyne coherent transmission, which is the highest QAM multiplicity realized with an injection locking technique. The frequency locking range of the local oscillator (LO) was as wide as 1 GHz. The phase noise...

Corticosteroids increase intracellular free sodium ion concentration via glucocorticoid receptor pathway in cultured neonatal rat cardiomyocytes.

International journal of cardiology. Heart & vessels

Katoh D, Hongo K, Ito K, Yoshino T, Kayama Y, Kawai M, Date T, Yoshimura M, Youngs P.
PMID: 29450170
Int J Cardiol Heart Vessel. 2014 Mar 13;3:49-56. doi: 10.1016/j.ijchv.2014.03.001. eCollection 2014 Jun.

BACKGROUND: Glucocorticoids as well as mineralocorticoid have been shown to play essential roles in the regulation of electrical and mechanical activities in cardiomyocytes. Excess of these hormones is an independent risk factor for cardiovascular disease. Intracellular sodium ([NaMETHODS AND...

1.5μm, mode-hop-free full C-band wavelength tunable laser diode with a linewidth of 8 kHz and a RIN of -130 dB/Hz and its extension to the L-band.

Optics express

Kasai K, Nakazawa M, Tomomatsu Y, Endo T.
PMID: 29041500
Opt Express. 2017 Sep 04;25(18):22113-22124. doi: 10.1364/OE.25.022113.

We demonstrate a narrow-linewidth, low-intensity noise, widely wavelength-tunable LD for which we adopted a long external cavity configuration (ECLD) with a tunable optical filter. By employing a simultaneous tuning circuit between the optical filter and the Fabry-Perot mode caused...

Fast 3D visualization of endogenous brain signals with high-sensitivity laser scanning photothermal microscopy.

Biomedical optics express

Miyazaki J, Iida T, Tanaka S, Hayashi-Takagi A, Kasai H, Okabe S, Kobayashi T.
PMID: 27231615
Biomed Opt Express. 2016 Apr 05;7(5):1702-10. doi: 10.1364/BOE.7.001702. eCollection 2016 May 01.

A fast, high-sensitivity photothermal microscope was developed by implementing a spatially segmented balanced detection scheme into a laser scanning microscope. We confirmed a 4.9 times improvement in signal-to-noise ratio in the spatially segmented balanced detection compared with that of...

AQUATIC PLANT SPECIATION AFFECTED BY DIVERSIFYING SELECTION OF ORGANELLE DNA REGIONS(1).

Journal of phycology

Kato S, Misawa K, Takahashi F, Sakayama H, Sano S, Kosuge K, Kasai F, Watanabe MM, Tanaka J, Nozaki H.
PMID: 27020181
J Phycol. 2011 Oct;47(5):999-1008. doi: 10.1111/j.1529-8817.2011.01037.x. Epub 2011 Aug 22.

Many of the genes that control photosynthesis are carried in the chloroplast. These genes differ among species. However, evidence has yet to be reported revealing the involvement of organelle genes in the initial stages of plant speciation. To elucidate...

Design and synthesis of a new chromophore, 2-(4-nitrophenyl)benzofuran, for two-photon uncaging using near-IR light.

Chemical communications (Cambridge, England)

Komori N, Jakkampudi S, Motoishi R, Abe M, Kamada K, Furukawa K, Katan C, Sawada W, Takahashi N, Kasai H, Xue B, Kobayashi T.
PMID: 26515230
Chem Commun (Camb). 2016 Jan 07;52(2):331-4. doi: 10.1039/c5cc07664a. Epub 2015 Oct 30.

A new chromophore, 2-(4-nitrophenyl)benzofuran (NPBF), was designed for two-photon (TP) uncaging using near-IR light. The TP absorption (TPA) cross-sections of the newly designed NPBF chromophore were determined to be 18 GM at 720 nm and 54 GM at 740...

Revealing the slow decomposition kinetics of type-I clathrate Ba.

Physical chemistry chemical physics : PCCP

Reardon H, Blichfeld AB, Kasai H, Yin H, Bøjesen ED, Iversen BB.
PMID: 28598477
Phys Chem Chem Phys. 2017 Jun 21;19(24):15734-15744. doi: 10.1039/c7cp01753g.

Inconsistencies in high temperature thermoelectric property measurements of Ba

Showing 13 to 24 of 1730 entries