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Showing 13 to 24 of 123 entries
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A Case of Lead Encephalopathy.

British medical journal

Judd WR.
PMID: 20761474
Br Med J. 1904 Apr 16;1(2259):888-9. doi: 10.1136/bmj.1.2259.888.

No abstract available.

An "Imperfect" Contraceptive Society: Fertility and Contraception in Italy.

Population and development review

Gribaldo A, Judd MD, Kertzer DI.
PMID: 25045191
Popul Dev Rev. 2009 Sep;35(3):551-584. doi: 10.1111/j.1728-4457.2009.00296.x.

Italy represents an unexpected and in some ways paradoxical outcome in terms of fertility control: a drop to one of the lowest birth rates in the world has been accompanied by the preponderant use of "traditional" methods despite the...

An On-Surface Reaction Confined within a Porous Molecular Template.

Chemistry (Weinheim an der Bergstrasse, Germany)

Judd CJ, Champness NR, Saywell A.
PMID: 29065224
Chemistry. 2018 Jan 02;24(1):56-61. doi: 10.1002/chem.201704693. Epub 2017 Nov 15.

On-surface reactions based on metal-catalysed Ullmann coupling have been successfully employed to synthesise a wide variety of covalently coupled structures. Substrate chemistry and topology are both known to effect the progression of an on-surface reaction; offering routes to control...

Elucidating immunometabolic targets in glioblastoma.

American journal of cancer research

Agarwal P, Pajor MJ, Anson DM, Guda MR, Labak CM, Tsung AJ, Velpula KK.
PMID: 29119048
Am J Cancer Res. 2017 Oct 01;7(10):1990-1995. eCollection 2017.

Immunometabolism has recently emerged on the forefront of cancer research as a new avenue to potentially develop more effective and targeted treatment options. Several pathologically altered metabolic targets across various cancer types have been identified, including lactate in aerobic...

Avoid Cohen's 'Small', 'Medium', and 'Large' for Power Analysis.

Trends in cognitive sciences

Correll J, Mellinger C, McClelland GH, Judd CM.
PMID: 31954629
Trends Cogn Sci. 2020 Mar;24(3):200-207. doi: 10.1016/j.tics.2019.12.009. Epub 2020 Jan 15.

One of the most difficult and important decisions in power analysis involves specifying an effect size. Researchers frequently employ definitions of small, medium, and large that were proposed by Jacob Cohen. These definitions are problematic for two reasons. First,...

Statistical difficulties of detecting interactions and moderator effects.

Psychological bulletin

McClelland GH, Judd CM.
PMID: 8416037
Psychol Bull. 1993 Sep;114(2):376-90. doi: 10.1037/0033-2909.114.2.376.

Although interaction effects are frequently found in experimental studies, field researchers report considerable difficulty in finding theorized moderator effects. Previous discussions of this discrepancy have considered responsible factors including differences in measurement error and use of nonlinear scales. In...

Structure-Based Design of A-1293102, a Potent and Selective BCL-X.

ACS medicinal chemistry letters

Tao ZF, Wang X, Chen J, Ingram JP, Jin S, Judge RA, Kovar PJ, Park C, Sun C, Wakefield BD, Zhou L, Zhang H, Elmore SW, Phillips DC, Judd AS, Leverson JD, Souers AJ.
PMID: 34141086
ACS Med Chem Lett. 2021 May 12;12(6):1011-1016. doi: 10.1021/acsmedchemlett.1c00162. eCollection 2021 Jun 10.

BCL-X

Metformin Treatment in Old Rats and Effects on Mitochondrial Integrity.

Rejuvenation research

Herbst A, Hoang A, Kim C, Aiken JM, McKenzie D, Goldwater DS, Wanagat J.
PMID: 34779265
Rejuvenation Res. 2021 Dec;24(6):434-440. doi: 10.1089/rej.2021.0052.

Metformin, a commonly used well-tolerated treatment for type 2 diabetes, is being deployed in clinical trials to ameliorate aging in older nondiabetic humans. Concerningly, some experiments in model organisms have suggested that metformin use at old ages shortens life...

Enhancement of Tryptic Peptide Signals from Tissue Sections Using MALDI IMS Postionization (MALDI-2).

Journal of the American Society for Mass Spectrometry

McMillen JC, Gutierrez DB, Judd AM, Spraggins JM, Caprioli RM.
PMID: 34515472
J Am Soc Mass Spectrom. 2021 Oct 06;32(10):2583-2591. doi: 10.1021/jasms.1c00213. Epub 2021 Sep 13.

Matrix-assisted laser desorption/ionization imaging mass spectrometry (MALDI IMS) allows for highly multiplexed, unlabeled mapping of analytes from tissue sections. However, further work is needed to improve the sensitivity and depth of coverage for protein and peptide IMS. We demonstrate...

Enhanced synthesis of oxo-verdazyl radicals bearing sterically-and electronically-diverse C3-substituents.

Organic & biomolecular chemistry

Fuller RO, Taylor MR, Duggin M, Bissember AC, Canty AJ, Judd MM, Cox N, Moggach SA, Turner GF.
PMID: 34757372
Org Biomol Chem. 2021 Dec 01;19(46):10120-10138. doi: 10.1039/d1ob01946e.

The synthetic viability of the hydrazine- and phosgene-free synthesis of 1,5-dimethyl oxo-verdazyl radicals has been improved

New recommendations for testing indirect effects in mediational models: The need to report and test component paths.

Journal of personality and social psychology

Yzerbyt V, Muller D, Batailler C, Judd CM.
PMID: 30550319
J Pers Soc Psychol. 2018 Dec;115(6):929-943. doi: 10.1037/pspa0000132.

In light of current concerns with replicability and reporting false-positive effects in psychology, we examine Type I errors and power associated with 2 distinct approaches for the assessment of mediation, namely the component approach (testing individual parameter estimates in...

Characterization of brain tumor initiating cells isolated from an animal model of CNS primitive neuroectodermal tumors.

Oncotarget

Malchenko S, Sredni ST, Boyineni J, Bi Y, Margaryan NV, Guda MR, Kostenko Y, Tomita T, Davuluri RV, Velpula K, Hendrix MJC, Soares MB.
PMID: 29568390
Oncotarget. 2018 Feb 09;9(17):13733-13747. doi: 10.18632/oncotarget.24460. eCollection 2018 Mar 02.

CNS Primitive Neuroectodermal tumors (CNS-PNETs) are members of the embryonal family of malignant childhood brain tumors, which remain refractory to current therapeutic treatments. Current paradigm of brain tumorigenesis implicates brain tumor-initiating cells (BTIC) in the onset of tumorigenesis and...

Showing 13 to 24 of 123 entries