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Phase 2 Study of Dabrafenib Plus Trametinib in Patients With BRAF V600E-Mutant Metastatic NSCLC: Updated 5-Year Survival Rates and Genomic Analysis.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

Planchard D, Besse B, Groen HJM, Hashemi SMS, Mazieres J, Kim TM, Quoix E, Souquet PJ, Barlesi F, Baik C, Villaruz LC, Kelly RJ, Zhang S, Tan M, Gasal E, Santarpia L, Johnson BE.
PMID: 34455067
J Thorac Oncol. 2022 Jan;17(1):103-115. doi: 10.1016/j.jtho.2021.08.011. Epub 2021 Aug 26.

INTRODUCTION: Dabrafenib plus trametinib was found to have robust antitumor activity in patients with BRAF V600E-mutant metastatic NSCLC (mNSCLC). We report updated survival analysis of a phase 2 study (NCT01336634) with a minimum of 5-year follow-up and updated genomic...

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Planchard D, Besse B, Groen HJM, et al. Phase 2 Study of Dabrafenib Plus Trametinib in Patients With BRAF V600E-Mutant Metastatic NSCLC: Updated 5-Year Survival Rates and Genomic Analysis. J Thorac Oncol. 2021;17(1):103-115doi: 10.1016/j.jtho.2021.08.011.
Planchard, D., Besse, B., Groen, H. J. M., Hashemi, S. M. S., Mazieres, J., Kim, T. M., Quoix, E., Souquet, P. J., Barlesi, F., Baik, C., Villaruz, L. C., Kelly, R. J., Zhang, S., Tan, M., Gasal, E., Santarpia, L., & Johnson, B. E. (2022). Phase 2 Study of Dabrafenib Plus Trametinib in Patients With BRAF V600E-Mutant Metastatic NSCLC: Updated 5-Year Survival Rates and Genomic Analysis. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 17(1), 103-115. https://doi.org/10.1016/j.jtho.2021.08.011
Planchard, David, et al. "Phase 2 Study of Dabrafenib Plus Trametinib in Patients With BRAF V600E-Mutant Metastatic NSCLC: Updated 5-Year Survival Rates and Genomic Analysis." Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer vol. 17,1 (2022): 103-115. doi: https://doi.org/10.1016/j.jtho.2021.08.011
Planchard D, Besse B, Groen HJM, Hashemi SMS, Mazieres J, Kim TM, Quoix E, Souquet PJ, Barlesi F, Baik C, Villaruz LC, Kelly RJ, Zhang S, Tan M, Gasal E, Santarpia L, Johnson BE. Phase 2 Study of Dabrafenib Plus Trametinib in Patients With BRAF V600E-Mutant Metastatic NSCLC: Updated 5-Year Survival Rates and Genomic Analysis. J Thorac Oncol. 2022 Jan;17(1):103-115. doi: 10.1016/j.jtho.2021.08.011. Epub 2021 Aug 26. PMID: 34455067.
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Colonic epithelial adaptation to EGFR-independent growth induces chromosomal instability and is accelerated by prior injury.

Neoplasia (New York, N.Y.)

Chen T, Zeineldin M, Johnson BA, Dong Y, Narkar A, Li T, Zhu J, Li R, Larman TC.
PMID: 33906087
Neoplasia. 2021 May;23(5):488-501. doi: 10.1016/j.neo.2021.03.010. Epub 2021 Apr 24.

Although much is known about the gene mutations required to drive colorectal cancer (CRC) initiation, the tissue-specific selective microenvironments in which neoplasia arises remains less characterized. Here, we determined whether modulation of intestinal stem cell niche morphogens alone can...

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Chen T, Zeineldin M, Johnson BA, et al. Colonic epithelial adaptation to EGFR-independent growth induces chromosomal instability and is accelerated by prior injury. Neoplasia. 2021;23(5):488-501doi: 10.1016/j.neo.2021.03.010.
Chen, T., Zeineldin, M., Johnson, B. A., Dong, Y., Narkar, A., Li, T., Zhu, J., Li, R., & Larman, T. C. (2021). Colonic epithelial adaptation to EGFR-independent growth induces chromosomal instability and is accelerated by prior injury. Neoplasia (New York, N.Y.), 23(5), 488-501. https://doi.org/10.1016/j.neo.2021.03.010
Chen, Tiane, et al. "Colonic epithelial adaptation to EGFR-independent growth induces chromosomal instability and is accelerated by prior injury." Neoplasia (New York, N.Y.) vol. 23,5 (2021): 488-501. doi: https://doi.org/10.1016/j.neo.2021.03.010
Chen T, Zeineldin M, Johnson BA, Dong Y, Narkar A, Li T, Zhu J, Li R, Larman TC. Colonic epithelial adaptation to EGFR-independent growth induces chromosomal instability and is accelerated by prior injury. Neoplasia. 2021 May;23(5):488-501. doi: 10.1016/j.neo.2021.03.010. Epub 2021 Apr 24. PMID: 33906087; PMCID: PMC8099723.
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Letter to the Editor: Oral Vancomycin Versus No Therapy for Pediatric Primary Sclerosing Cholangitis.

Hepatology (Baltimore, Md.)

Johnson KM, Fischer RT, Holtmann GJ, Shah A, Alrabadi L, Lewindon P.
PMID: 33638221
Hepatology. 2021 Sep;74(3):1716-1717. doi: 10.1002/hep.31764. Epub 2021 May 21.

No abstract available.

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Johnson KM, Fischer RT, Holtmann GJ, et al. Letter to the Editor: Oral Vancomycin Versus No Therapy for Pediatric Primary Sclerosing Cholangitis. Hepatology. 2021;74(3):1716-1717doi: 10.1002/hep.31764.
Johnson, K. M., Fischer, R. T., Holtmann, G. J., Shah, A., Alrabadi, L., & Lewindon, P. (2021). Letter to the Editor: Oral Vancomycin Versus No Therapy for Pediatric Primary Sclerosing Cholangitis. Hepatology (Baltimore, Md.), 74(3), 1716-1717. https://doi.org/10.1002/hep.31764
Johnson, Kevin M, et al. "Letter to the Editor: Oral Vancomycin Versus No Therapy for Pediatric Primary Sclerosing Cholangitis." Hepatology (Baltimore, Md.) vol. 74,3 (2021): 1716-1717. doi: https://doi.org/10.1002/hep.31764
Johnson KM, Fischer RT, Holtmann GJ, Shah A, Alrabadi L, Lewindon P. Letter to the Editor: Oral Vancomycin Versus No Therapy for Pediatric Primary Sclerosing Cholangitis. Hepatology. 2021 Sep;74(3):1716-1717. doi: 10.1002/hep.31764. Epub 2021 May 21. PMID: 33638221.
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The three-dimensional construction of leaves is coordinated with water use efficiency in conifers.

The New phytologist

Trueba S, Théroux-Rancourt G, Earles JM, Buckley TN, Love D, Johnson DM, Brodersen C.
PMID: 34614205
New Phytol. 2021 Oct 06; doi: 10.1111/nph.17772. Epub 2021 Oct 06.

Conifers prevail in the canopies of many terrestrial biomes, holding a great ecological and economic importance globally. Current increases in temperature and aridity are imposing high transpirational demands and resulting in conifer mortality. Therefore, identifying leaf structural determinants of...

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Trueba S, Théroux-Rancourt G, Earles JM, et al. The three-dimensional construction of leaves is coordinated with water use efficiency in conifers. New Phytol. 2021;doi: 10.1111/nph.17772.
Trueba, S., Théroux-Rancourt, G., Earles, J. M., Buckley, T. N., Love, D., Johnson, D. M., & Brodersen, C. (2021). The three-dimensional construction of leaves is coordinated with water use efficiency in conifers. The New phytologist, . https://doi.org/10.1111/nph.17772
Trueba, Santiago, et al. "The three-dimensional construction of leaves is coordinated with water use efficiency in conifers." The New phytologist vol. (2021). doi: https://doi.org/10.1111/nph.17772
Trueba S, Théroux-Rancourt G, Earles JM, Buckley TN, Love D, Johnson DM, Brodersen C. The three-dimensional construction of leaves is coordinated with water use efficiency in conifers. New Phytol. 2021 Oct 06; doi: 10.1111/nph.17772. Epub 2021 Oct 06. PMID: 34614205.
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The Use of Automated Traps to Assess the Efficacy of Insecticide Barrier Treatments Against Abundant Mosquitoes in Remote Environments.

Journal of medical entomology

Johnson BJ, Manby R, Devine GJ.
PMID: 34748002
J Med Entomol. 2022 Jan 12;59(1):384-389. doi: 10.1093/jme/tjab178.

Commercially available 'smart' trap technology has not yet been widely used to evaluate interventions against mosquitoes despite potential benefits. These benefits include the ability to capture data continuously at fine temporal scales without the human resources usually required for...

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Johnson BJ, Manby R, Devine GJ. The Use of Automated Traps to Assess the Efficacy of Insecticide Barrier Treatments Against Abundant Mosquitoes in Remote Environments. J Med Entomol. 2022;59(1):384-389doi: 10.1093/jme/tjab178.
Johnson, B. J., Manby, R., & Devine, G. J. (2022). The Use of Automated Traps to Assess the Efficacy of Insecticide Barrier Treatments Against Abundant Mosquitoes in Remote Environments. Journal of medical entomology, 59(1), 384-389. https://doi.org/10.1093/jme/tjab178
Johnson, Brian J, et al. "The Use of Automated Traps to Assess the Efficacy of Insecticide Barrier Treatments Against Abundant Mosquitoes in Remote Environments." Journal of medical entomology vol. 59,1 (2022): 384-389. doi: https://doi.org/10.1093/jme/tjab178
Johnson BJ, Manby R, Devine GJ. The Use of Automated Traps to Assess the Efficacy of Insecticide Barrier Treatments Against Abundant Mosquitoes in Remote Environments. J Med Entomol. 2022 Jan 12;59(1):384-389. doi: 10.1093/jme/tjab178. PMID: 34748002.
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Delta spike P681R mutation enhances SARS-CoV-2 fitness over Alpha variant.

bioRxiv : the preprint server for biology

Liu Y, Liu J, Johnson BA, Xia H, Ku Z, Schindewolf C, Widen SG, An Z, Weaver SC, Menachery VD, Xie X, Shi PY.
PMID: 34462752
bioRxiv. 2021 Sep 05; doi: 10.1101/2021.08.12.456173.

SARS-CoV-2 Delta variant has rapidly replaced the Alpha variant around the world. The mechanism that drives this global replacement has not been defined. Here we report that Delta spike mutation P681R plays a key role in the Alpha-to-Delta variant...

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Liu Y, Liu J, Johnson BA, et al. Delta spike P681R mutation enhances SARS-CoV-2 fitness over Alpha variant. bioRxiv. 2021;doi: 10.1101/2021.08.12.456173.
Liu, Y., Liu, J., Johnson, B. A., Xia, H., Ku, Z., Schindewolf, C., Widen, S. G., An, Z., Weaver, S. C., Menachery, V. D., Xie, X., & Shi, P. Y. (2021). Delta spike P681R mutation enhances SARS-CoV-2 fitness over Alpha variant. bioRxiv : the preprint server for biology, . https://doi.org/10.1101/2021.08.12.456173
Liu, Yang, et al. "Delta spike P681R mutation enhances SARS-CoV-2 fitness over Alpha variant." bioRxiv : the preprint server for biology vol. (2021). doi: https://doi.org/10.1101/2021.08.12.456173
Liu Y, Liu J, Johnson BA, Xia H, Ku Z, Schindewolf C, Widen SG, An Z, Weaver SC, Menachery VD, Xie X, Shi PY. Delta spike P681R mutation enhances SARS-CoV-2 fitness over Alpha variant. bioRxiv. 2021 Sep 05; doi: 10.1101/2021.08.12.456173. PMID: 34462752; PMCID: PMC8404900.
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Shock Pressure Dependence of Hot Spots in a Model Plastic-Bonded Explosive.

The journal of physical chemistry. A

Johnson BP, Zhou X, Dlott DD.
PMID: 34982934
J Phys Chem A. 2022 Jan 13;126(1):145-154. doi: 10.1021/acs.jpca.1c08323. Epub 2022 Jan 04.

Shock initiation of plastic-bonded explosives (PBX) begins with the formation of so-called "hot spots", which are energetic reactions localized in regions where the PBX microstructure concentrates the input shock wave energy. We developed a model PBX system to study...

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Johnson BP, Zhou X, Dlott DD. Shock Pressure Dependence of Hot Spots in a Model Plastic-Bonded Explosive. J Phys Chem A. 2022;126(1):145-154doi: 10.1021/acs.jpca.1c08323.
Johnson, B. P., Zhou, X., & Dlott, D. D. (2022). Shock Pressure Dependence of Hot Spots in a Model Plastic-Bonded Explosive. The journal of physical chemistry. A, 126(1), 145-154. https://doi.org/10.1021/acs.jpca.1c08323
Johnson, Belinda P, et al. "Shock Pressure Dependence of Hot Spots in a Model Plastic-Bonded Explosive." The journal of physical chemistry. A vol. 126,1 (2022): 145-154. doi: https://doi.org/10.1021/acs.jpca.1c08323
Johnson BP, Zhou X, Dlott DD. Shock Pressure Dependence of Hot Spots in a Model Plastic-Bonded Explosive. J Phys Chem A. 2022 Jan 13;126(1):145-154. doi: 10.1021/acs.jpca.1c08323. Epub 2022 Jan 04. PMID: 34982934.
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Addiction and "Generation Me:" Narcissistic and Prosocial Behaviors of Adolescents with Substance Dependency Disorder in Comparison to Normative Adolescents.

Alcoholism treatment quarterly

Carter RR, Johnson SM, Exline JJ, Post SG, Pagano ME.
PMID: 22544995
Alcohol Treat Q. 2012;30(2):163-178. doi: 10.1080/07347324.2012.663286. Epub 2012 Apr 13.

The purpose of this study is to explore narcissistic and prosocial behaviors as reported by adolescents with and without substance dependency disorder (SDD). This study employs a quasi-experimental design using SDD adolescents compared with two normative samples of adolescents....

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Carter RR, Johnson SM, Exline JJ, et al. Addiction and "Generation Me:" Narcissistic and Prosocial Behaviors of Adolescents with Substance Dependency Disorder in Comparison to Normative Adolescents. Alcohol Treat Q. 2012;30(2):163-178doi: 10.1080/07347324.2012.663286.
Carter, R. R., Johnson, S. M., Exline, J. J., Post, S. G., & Pagano, M. E. (2012). Addiction and "Generation Me:" Narcissistic and Prosocial Behaviors of Adolescents with Substance Dependency Disorder in Comparison to Normative Adolescents. Alcoholism treatment quarterly, 30(2), 163-178. https://doi.org/10.1080/07347324.2012.663286
Carter, Rebecca R, et al. "Addiction and "Generation Me:" Narcissistic and Prosocial Behaviors of Adolescents with Substance Dependency Disorder in Comparison to Normative Adolescents." Alcoholism treatment quarterly vol. 30,2 (2012): 163-178. doi: https://doi.org/10.1080/07347324.2012.663286
Carter RR, Johnson SM, Exline JJ, Post SG, Pagano ME. Addiction and "Generation Me:" Narcissistic and Prosocial Behaviors of Adolescents with Substance Dependency Disorder in Comparison to Normative Adolescents. Alcohol Treat Q. 2012;30(2):163-178. doi: 10.1080/07347324.2012.663286. Epub 2012 Apr 13. PMID: 22544995; PMCID: PMC3335730.
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Wild bats briefly decouple sound production from wingbeats to increase sensory flow during prey captures.

iScience

Stidsholt L, Johnson M, Goerlitz HR, Madsen PT.
PMID: 34401675
iScience. 2021 Jul 22;24(8):102896. doi: 10.1016/j.isci.2021.102896. eCollection 2021 Aug 20.

Active sensing animals such as echolocating bats produce the energy with which they probe their environment. The intense echolocation calls of bats are energetically expensive, but their cost can be reduced by synchronizing the exhalations needed to vocalize to...

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Stidsholt L, Johnson M, Goerlitz HR, et al. Wild bats briefly decouple sound production from wingbeats to increase sensory flow during prey captures. iScience. 2021;24(8):102896doi: 10.1016/j.isci.2021.102896.
Stidsholt, L., Johnson, M., Goerlitz, H. R., & Madsen, P. T. (2021). Wild bats briefly decouple sound production from wingbeats to increase sensory flow during prey captures. iScience, 24(8), 102896. https://doi.org/10.1016/j.isci.2021.102896
Stidsholt, Laura, et al. "Wild bats briefly decouple sound production from wingbeats to increase sensory flow during prey captures." iScience vol. 24,8 (2021): 102896. doi: https://doi.org/10.1016/j.isci.2021.102896
Stidsholt L, Johnson M, Goerlitz HR, Madsen PT. Wild bats briefly decouple sound production from wingbeats to increase sensory flow during prey captures. iScience. 2021 Jul 22;24(8):102896. doi: 10.1016/j.isci.2021.102896. eCollection 2021 Aug 20. PMID: 34401675; PMCID: PMC8355945.
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Hands-on optics: an informal science education initiative - art. no. 66680D.

Johnson AM, Pompea SM, Arthurs EG, Walker CE, Sparks RT.
UIID-AD: 1057
2007;6668. doi: 10.1117/12.740568.

The project is collaboration between two scientific societies, the Optical Society of America (OSA) and SPIE - The International Society for Optical Engineering and the National Optical Astronomy Observatory (NOAO). The program is designed to bring science education enrichment...

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Johnson AM, Pompea SM, Arthurs EG, et al. Hands-on optics: an informal science education initiative - art. no. 66680D. 2007;6668doi: 10.1117/12.740568.
Johnson, A. M., Pompea, S. M., Arthurs, E. G., Walker, C. E., & Sparks, R. T. (2007). Hands-on optics: an informal science education initiative - art. no. 66680D. 6668. https://doi.org/10.1117/12.740568
Johnson, A M, et al. "Hands-on optics: an informal science education initiative - art. no. 66680D." vol. 6668 (2007). doi: https://doi.org/10.1117/12.740568
Johnson AM, Pompea SM, Arthurs EG, Walker CE, Sparks RT. Hands-on optics: an informal science education initiative - art. no. 66680D. 2007;6668. doi: 10.1117/12.740568. UIID-AD: 1057.
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Creating More Effective Mentors: Mentoring the Mentor.

Johnson M, Gandhi M.
UIID-AD: 3646
2016;294-303. doi: 10.1007/s10461-016-1364-3.

Given the diversity of those affected by HIV, increasing diversity in the HIV biomedical research workforce is imperative. A growing body of empirical and experimental evidence supports the importance of strong mentorship in the development and success of trainees...

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Johnson M, Gandhi M. Creating More Effective Mentors: Mentoring the Mentor. 2016;294-303doi: 10.1007/s10461-016-1364-3.
Johnson, M., & Gandhi, M. (2016). Creating More Effective Mentors: Mentoring the Mentor. 294-303. https://doi.org/10.1007/s10461-016-1364-3
Johnson, M, and Gandhi, M. "Creating More Effective Mentors: Mentoring the Mentor." vol. (2016): 294-303. doi: https://doi.org/10.1007/s10461-016-1364-3
Johnson M, Gandhi M. Creating More Effective Mentors: Mentoring the Mentor. 2016;294-303. doi: 10.1007/s10461-016-1364-3. UIID-AD: 3646.
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Showing 3517 to 3527 of 3527 entries