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IgA Plasma Cells Are Long-Lived Residents of Gut and Bone Marrow That Express Isotype- and Tissue-Specific Gene Expression Patterns.

Frontiers in immunology

Wilmore JR, Gaudette BT, Gómez Atria D, Rosenthal RL, Reiser SK, Meng W, Rosenfeld AM, Luning Prak ET, Allman D.
PMID: 35003110
Front Immunol. 2021 Dec 24;12:791095. doi: 10.3389/fimmu.2021.791095. eCollection 2021.

Antibody secreting plasma cells are made in response to a variety of pathogenic and commensal microbes. While all plasma cells express a core gene transcription program that allows them to secrete large quantities of immunoglobulin, unique transcriptional profiles are...

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Wilmore JR, Gaudette BT, Gómez Atria D, et al. IgA Plasma Cells Are Long-Lived Residents of Gut and Bone Marrow That Express Isotype- and Tissue-Specific Gene Expression Patterns. Front Immunol. 2021;12:791095doi: 10.3389/fimmu.2021.791095.
Wilmore, J. R., Gaudette, B. T., Gómez Atria, D., Rosenthal, R. L., Reiser, S. K., Meng, W., Rosenfeld, A. M., Luning Prak, E. T., & Allman, D. (2021). IgA Plasma Cells Are Long-Lived Residents of Gut and Bone Marrow That Express Isotype- and Tissue-Specific Gene Expression Patterns. Frontiers in immunology, 12791095. https://doi.org/10.3389/fimmu.2021.791095
Wilmore, Joel R, et al. "IgA Plasma Cells Are Long-Lived Residents of Gut and Bone Marrow That Express Isotype- and Tissue-Specific Gene Expression Patterns." Frontiers in immunology vol. 12 (2021): 791095. doi: https://doi.org/10.3389/fimmu.2021.791095
Wilmore JR, Gaudette BT, Gómez Atria D, Rosenthal RL, Reiser SK, Meng W, Rosenfeld AM, Luning Prak ET, Allman D. IgA Plasma Cells Are Long-Lived Residents of Gut and Bone Marrow That Express Isotype- and Tissue-Specific Gene Expression Patterns. Front Immunol. 2021 Dec 24;12:791095. doi: 10.3389/fimmu.2021.791095. eCollection 2021. PMID: 35003110; PMCID: PMC8739487.
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Clinical utility of brain MRS imaging of patients with adult-onset non-cirrhotic hyperammonemia.

Molecular genetics and metabolism reports

Stergachis AB, Krier JB, Merugumala SK, Berry GT, Lin AP.
PMID: 33763331
Mol Genet Metab Rep. 2021 Mar 13;27:100742. doi: 10.1016/j.ymgmr.2021.100742. eCollection 2021 Jun.

Adult-onset non-cirrhotic hyperammonemia (NCH) is a rare, but often fatal condition that can result in both reversible and irreversible neurological defects. Here we present five cases of adult-onset non-cirrhotic hyperammonemia wherein brain magnetic resonance spectroscopy (MRS) scans for cerebral...

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Stergachis AB, Krier JB, Merugumala SK, et al. Clinical utility of brain MRS imaging of patients with adult-onset non-cirrhotic hyperammonemia. Mol Genet Metab Rep. 2021;27:100742doi: 10.1016/j.ymgmr.2021.100742.
Stergachis, A. B., Krier, J. B., Merugumala, S. K., Berry, G. T., & Lin, A. P. (2021). Clinical utility of brain MRS imaging of patients with adult-onset non-cirrhotic hyperammonemia. Molecular genetics and metabolism reports, 27100742. https://doi.org/10.1016/j.ymgmr.2021.100742
Stergachis, Andrew B, et al. "Clinical utility of brain MRS imaging of patients with adult-onset non-cirrhotic hyperammonemia." Molecular genetics and metabolism reports vol. 27 (2021): 100742. doi: https://doi.org/10.1016/j.ymgmr.2021.100742
Stergachis AB, Krier JB, Merugumala SK, Berry GT, Lin AP. Clinical utility of brain MRS imaging of patients with adult-onset non-cirrhotic hyperammonemia. Mol Genet Metab Rep. 2021 Mar 13;27:100742. doi: 10.1016/j.ymgmr.2021.100742. eCollection 2021 Jun. PMID: 33763331; PMCID: PMC7973242.
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Phase I study of cediranib, an oral VEGFR inhibitor, in combination with selumetinib, an oral MEK inhibitor, in patients with advanced solid malignancies.

Investigational new drugs

Hubbard JM, Yin J, Schenk EL, Qin R, Reid JM, Strand C, Fiskum J, Menefee M, Lin G, Doyle LA, Ivy P, Erlichman C, Adjei A, Haluska P, Costello BA.
PMID: 34515877
Invest New Drugs. 2022 Feb;40(1):115-123. doi: 10.1007/s10637-021-01175-6. Epub 2021 Sep 13.

PURPOSE: Targeting the vascular endothelial growth factor (VEGF) pathway improves progression free survival in multiple advanced malignancies but durable responses are uncommon. Inhibition of the VEGF pathway at multiple levels of signal transduction may improve clinical outcomes. Preclinical data...

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Hubbard JM, Yin J, Schenk EL, et al. Phase I study of cediranib, an oral VEGFR inhibitor, in combination with selumetinib, an oral MEK inhibitor, in patients with advanced solid malignancies. Invest New Drugs. 2021;40(1):115-123doi: 10.1007/s10637-021-01175-6.
Hubbard, J. M., Yin, J., Schenk, E. L., Qin, R., Reid, J. M., Strand, C., Fiskum, J., Menefee, M., Lin, G., Doyle, L. A., Ivy, P., Erlichman, C., Adjei, A., Haluska, P., & Costello, B. A. (2022). Phase I study of cediranib, an oral VEGFR inhibitor, in combination with selumetinib, an oral MEK inhibitor, in patients with advanced solid malignancies. Investigational new drugs, 40(1), 115-123. https://doi.org/10.1007/s10637-021-01175-6
Hubbard, Joleen M, et al. "Phase I study of cediranib, an oral VEGFR inhibitor, in combination with selumetinib, an oral MEK inhibitor, in patients with advanced solid malignancies." Investigational new drugs vol. 40,1 (2022): 115-123. doi: https://doi.org/10.1007/s10637-021-01175-6
Hubbard JM, Yin J, Schenk EL, Qin R, Reid JM, Strand C, Fiskum J, Menefee M, Lin G, Doyle LA, Ivy P, Erlichman C, Adjei A, Haluska P, Costello BA. Phase I study of cediranib, an oral VEGFR inhibitor, in combination with selumetinib, an oral MEK inhibitor, in patients with advanced solid malignancies. Invest New Drugs. 2022 Feb;40(1):115-123. doi: 10.1007/s10637-021-01175-6. Epub 2021 Sep 13. PMID: 34515877.
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Citicoline Modulates Glaucomatous Neurodegeneration Through Intraocular Pressure-Independent Control.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics

van der Merwe Y, Murphy MC, Sims JR, Faiq MA, Yang XL, Ho LC, Conner IP, Yu Y, Leung CK, Wollstein G, Schuman JS, Chan KC.
PMID: 33846961
Neurotherapeutics. 2021 Apr;18(2):1339-1359. doi: 10.1007/s13311-021-01033-6. Epub 2021 Apr 13.

Glaucoma is a neurodegenerative disease that causes progressive, irreversible vision loss. Currently, intraocular pressure (IOP) is the only modifiable risk factor for glaucoma. However, glaucomatous degeneration may continue despite adequate IOP control. Therefore, there exists a need for treatment...

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van der Merwe Y, Murphy MC, Sims JR, et al. Citicoline Modulates Glaucomatous Neurodegeneration Through Intraocular Pressure-Independent Control. Neurotherapeutics. 2021;18(2):1339-1359doi: 10.1007/s13311-021-01033-6.
van der Merwe, Y., Murphy, M. C., Sims, J. R., Faiq, M. A., Yang, X. L., Ho, L. C., Conner, I. P., Yu, Y., Leung, C. K., Wollstein, G., Schuman, J. S., & Chan, K. C. (2021). Citicoline Modulates Glaucomatous Neurodegeneration Through Intraocular Pressure-Independent Control. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 18(2), 1339-1359. https://doi.org/10.1007/s13311-021-01033-6
van der Merwe, Yolandi, et al. "Citicoline Modulates Glaucomatous Neurodegeneration Through Intraocular Pressure-Independent Control." Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics vol. 18,2 (2021): 1339-1359. doi: https://doi.org/10.1007/s13311-021-01033-6
van der Merwe Y, Murphy MC, Sims JR, Faiq MA, Yang XL, Ho LC, Conner IP, Yu Y, Leung CK, Wollstein G, Schuman JS, Chan KC. Citicoline Modulates Glaucomatous Neurodegeneration Through Intraocular Pressure-Independent Control. Neurotherapeutics. 2021 Apr;18(2):1339-1359. doi: 10.1007/s13311-021-01033-6. Epub 2021 Apr 13. PMID: 33846961; PMCID: PMC8423893.
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Pediatric Endoscopy Quality Improvement Network (PEnQuIN) Pediatric Endoscopy Reporting Elements: A Joint NASPGHAN/ESPGHAN Guideline.

Journal of pediatric gastroenterology and nutrition

Lightdale JR, Walsh CM, Fishman DS, Furlano RI, Mamula P, Gillett PM, Narula P, Hojsak I, Oliva S, Homan M, Riley MR, Huynh HQ, Rosh JR, Jacobson K, Tavares M, Leibowitz IH, Utterson EC, Croft NM, Mack DR, Brill H, Liu QY, Bontems P, Lerner DG, Amil-Dias J, Kramer RE, Otley AR, Ambartsumyan L, Connan V, McCreath GA, Thomson MA.
PMID: 34402488
J Pediatr Gastroenterol Nutr. 2021 Aug 16; doi: 10.1097/MPG.0000000000003266. Epub 2021 Aug 16.

INTRODUCTION: High quality procedure reports are a cornerstone of high quality pediatric endoscopy as they ensure the clear communication of procedural events and outcomes, guide patient care and facilitate continuous quality improvement. The aim of this document is to...

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Lightdale JR, Walsh CM, Fishman DS, et al. Pediatric Endoscopy Quality Improvement Network (PEnQuIN) Pediatric Endoscopy Reporting Elements: A Joint NASPGHAN/ESPGHAN Guideline. J Pediatr Gastroenterol Nutr. 2021;doi: 10.1097/MPG.0000000000003266.
Lightdale, J. R., Walsh, C. M., Fishman, D. S., Furlano, R. I., Mamula, P., Gillett, P. M., Narula, P., Hojsak, I., Oliva, S., Homan, M., Riley, M. R., Huynh, H. Q., Rosh, J. R., Jacobson, K., Tavares, M., Leibowitz, I. H., Utterson, E. C., Croft, N. M., Mack, D. R., Brill, H., Liu, Q. Y., Bontems, P., Lerner, D. G., Amil-Dias, J., Kramer, R. E., Otley, A. R., Ambartsumyan, L., Connan, V., McCreath, G. A., Thomson, M. A. (2021). Pediatric Endoscopy Quality Improvement Network (PEnQuIN) Pediatric Endoscopy Reporting Elements: A Joint NASPGHAN/ESPGHAN Guideline. Journal of pediatric gastroenterology and nutrition, . https://doi.org/10.1097/MPG.0000000000003266
Lightdale, Jenifer R, et al. "Pediatric Endoscopy Quality Improvement Network (PEnQuIN) Pediatric Endoscopy Reporting Elements: A Joint NASPGHAN/ESPGHAN Guideline." Journal of pediatric gastroenterology and nutrition vol. (2021). doi: https://doi.org/10.1097/MPG.0000000000003266
Lightdale JR, Walsh CM, Fishman DS, Furlano RI, Mamula P, Gillett PM, Narula P, Hojsak I, Oliva S, Homan M, Riley MR, Huynh HQ, Rosh JR, Jacobson K, Tavares M, Leibowitz IH, Utterson EC, Croft NM, Mack DR, Brill H, Liu QY, Bontems P, Lerner DG, Amil-Dias J, Kramer RE, Otley AR, Ambartsumyan L, Connan V, McCreath GA, Thomson MA. Pediatric Endoscopy Quality Improvement Network (PEnQuIN) Pediatric Endoscopy Reporting Elements: A Joint NASPGHAN/ESPGHAN Guideline. J Pediatr Gastroenterol Nutr. 2021 Aug 16; doi: 10.1097/MPG.0000000000003266. Epub 2021 Aug 16. PMID: 34402488.
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Machine Learning: New Ideas and Tools in Environmental Science and Engineering.

Environmental science & technology

Zhong S, Zhang K, Bagheri M, Burken JG, Gu A, Li B, Ma X, Marrone BL, Ren ZJ, Schrier J, Shi W, Tan H, Wang T, Wang X, Wong BM, Xiao X, Yu X, Zhu JJ, Zhang H.
PMID: 34403250
Environ Sci Technol. 2021 Oct 05;55(19):12741-12754. doi: 10.1021/acs.est.1c01339. Epub 2021 Aug 17.

The rapid increase in both the quantity and complexity of data that are being generated daily in the field of environmental science and engineering (ESE) demands accompanied advancement in data analytics. Advanced data analysis approaches, such as machine learning...

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Zhong S, Zhang K, Bagheri M, et al. Machine Learning: New Ideas and Tools in Environmental Science and Engineering. Environ Sci Technol. 2021;55(19):12741-12754doi: 10.1021/acs.est.1c01339.
Zhong, S., Zhang, K., Bagheri, M., Burken, J. G., Gu, A., Li, B., Ma, X., Marrone, B. L., Ren, Z. J., Schrier, J., Shi, W., Tan, H., Wang, T., Wang, X., Wong, B. M., Xiao, X., Yu, X., Zhu, J. J., & Zhang, H. (2021). Machine Learning: New Ideas and Tools in Environmental Science and Engineering. Environmental science & technology, 55(19), 12741-12754. https://doi.org/10.1021/acs.est.1c01339
Zhong, Shifa, et al. "Machine Learning: New Ideas and Tools in Environmental Science and Engineering." Environmental science & technology vol. 55,19 (2021): 12741-12754. doi: https://doi.org/10.1021/acs.est.1c01339
Zhong S, Zhang K, Bagheri M, Burken JG, Gu A, Li B, Ma X, Marrone BL, Ren ZJ, Schrier J, Shi W, Tan H, Wang T, Wang X, Wong BM, Xiao X, Yu X, Zhu JJ, Zhang H. Machine Learning: New Ideas and Tools in Environmental Science and Engineering. Environ Sci Technol. 2021 Oct 05;55(19):12741-12754. doi: 10.1021/acs.est.1c01339. Epub 2021 Aug 17. PMID: 34403250.
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In Vivo Sublayer Analysis of Human Retinal Inner Plexiform Layer Obtained by Visible-Light Optical Coherence Tomography.

Investigative ophthalmology & visual science

Ghassabi Z, Kuranov RV, Schuman JS, Zambrano R, Wu M, Liu M, Tayebi B, Wang Y, Rubinoff I, Liu X, Wollstein G, Zhang HF, Ishikawa H.
PMID: 35024761
Invest Ophthalmol Vis Sci. 2022 Jan 03;63(1):18. doi: 10.1167/iovs.63.1.18.

PURPOSE: Growing evidence suggests that dendrite retraction or degeneration in a subpopulation of the retinal ganglion cells (RGCs) may precede detectable soma abnormalities and RGC death in glaucoma. Visualization of the lamellar structure of the inner plexiform layer (IPL)...

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Ghassabi Z, Kuranov RV, Schuman JS, et al. In Vivo Sublayer Analysis of Human Retinal Inner Plexiform Layer Obtained by Visible-Light Optical Coherence Tomography. Invest Ophthalmol Vis Sci. 2022;63(1):18doi: 10.1167/iovs.63.1.18.
Ghassabi, Z., Kuranov, R. V., Schuman, J. S., Zambrano, R., Wu, M., Liu, M., Tayebi, B., Wang, Y., Rubinoff, I., Liu, X., Wollstein, G., Zhang, H. F., & Ishikawa, H. (2022). In Vivo Sublayer Analysis of Human Retinal Inner Plexiform Layer Obtained by Visible-Light Optical Coherence Tomography. Investigative ophthalmology & visual science, 63(1), 18. https://doi.org/10.1167/iovs.63.1.18
Ghassabi, Zeinab, et al. "In Vivo Sublayer Analysis of Human Retinal Inner Plexiform Layer Obtained by Visible-Light Optical Coherence Tomography." Investigative ophthalmology & visual science vol. 63,1 (2022): 18. doi: https://doi.org/10.1167/iovs.63.1.18
Ghassabi Z, Kuranov RV, Schuman JS, Zambrano R, Wu M, Liu M, Tayebi B, Wang Y, Rubinoff I, Liu X, Wollstein G, Zhang HF, Ishikawa H. In Vivo Sublayer Analysis of Human Retinal Inner Plexiform Layer Obtained by Visible-Light Optical Coherence Tomography. Invest Ophthalmol Vis Sci. 2022 Jan 03;63(1):18. doi: 10.1167/iovs.63.1.18. PMID: 35024761.
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Showing 5629 to 5635 of 5635 entries