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Showing 13 to 24 of 5635 entries
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Extraction of total nucleic acids from bacterial isolates using the bioMérieux NucliSENS easyMAG total nucleic acid extractor.

Annals of clinical microbiology and antimicrobials

Powell EA, Mortensen JE.
PMID: 27658494
Ann Clin Microbiol Antimicrob. 2016 Sep 22;15(1):54. doi: 10.1186/s12941-016-0168-7.

The BioMerieux NucliSENS easyMAG total nucleic acid extractor was evaluated for use on bacterial isolates in the clinical microbiology laboratory. Forty eight isolates were extracted, yielding quantifiable amounts of DNA for all isolates. The easyMAG is appropriate for DNA...

Outcomes in patients with glenoid labral lesions: a cohort study.

BMJ open sport & exercise medicine

Zughaib M, Robbins CB, Miller BS, Gagnier JJ.
PMID: 28879037
BMJ Open Sport Exerc Med. 2017 Feb 21;2(1):e000209. doi: 10.1136/bmjsem-2016-000209. eCollection 2016.

BACKGROUND/AIM: For patients presenting with glenoid labral pathologies, there is little information on how operative interventions affect long-term outcomes and health-related quality of life (HRQoL). This study evaluated outcomes in operative and non-operative patients presenting with labral tears versus...

Tornado outbreak variability follows Taylor's power law of fluctuation scaling and increases dramatically with severity.

Nature communications

Tippett MK, Cohen JE.
PMID: 26923210
Nat Commun. 2016 Feb 29;7:10668. doi: 10.1038/ncomms10668.

Tornadoes cause loss of life and damage to property each year in the United States and around the world. The largest impacts come from 'outbreaks' consisting of multiple tornadoes closely spaced in time. Here we find an upward trend...

Safety and Efficacy of the Complement Inhibitor AMY-101 in a Natural Model of Periodontitis in Non-human Primates.

Molecular therapy. Methods & clinical development

Kajikawa T, Briones RA, Resuello RRG, Tuplano JV, Reis ES, Hajishengallis E, Garcia CAG, Yancopoulou D, Lambris JD, Hajishengallis G.
PMID: 28879212
Mol Ther Methods Clin Dev. 2017 Aug 18;6:207-215. doi: 10.1016/j.omtm.2017.08.001. eCollection 2017 Sep 15.

Periodontitis is a chronic inflammatory disease associated with overactivation of the complement system. Recent preclinical studies suggest that host-modulation therapies may contribute to effective treatment of human periodontitis, which may lead to loss of teeth and function if untreated....

Prescriber preferences for behavioural economics interventions to improve treatment of acute respiratory infections: a discrete choice experiment.

BMJ open

Gong CL, Hay JW, Meeker D, Doctor JN.
PMID: 27660322
BMJ Open. 2016 Sep 22;6(9):e012739. doi: 10.1136/bmjopen-2016-012739.

OBJECTIVE: To elicit prescribers' preferences for behavioural economics interventions designed to reduce inappropriate antibiotic prescribing, and compare these to actual behaviour.DESIGN: Discrete choice experiment (DCE).SETTING: 47 primary care centres in Boston and Los Angeles.PARTICIPANTS: 234 primary care providers, with...

Longitudinal and Cross-Sectional Analyses of Age Effects on Retinal Nerve Fiber Layer and Ganglion Cell Complex Thickness by Fourier-Domain OCT.

Translational vision science & technology

Zhang X, Francis BA, Dastiridou A, Chopra V, Tan O, Varma R, Greenfield DS, Schuman JS, Huang D.
PMID: 26966637
Transl Vis Sci Technol. 2016 Mar 04;5(2):1. doi: 10.1167/tvst.5.2.1. eCollection 2016 Mar.

PURPOSE: We studied the effects of age and intraocular pressure (IOP) on retinal nerve fiber layer (NFL) and macular ganglion cell complex (GCC) thickness in normal eyes.METHODS: Data from subjects from the multicenter Advanced Imaging for Glaucoma Study (AIGS)...

Is There an Association Between the "Critical Shoulder Angle" and Clinical Outcome After Rotator Cuff Repair?.

Orthopaedic journal of sports medicine

Kirsch JM, Nathani A, Robbins CB, Gagnier JJ, Bedi A, Miller BS.
PMID: 28451621
Orthop J Sports Med. 2017 Apr 18;5(4):2325967117702126. doi: 10.1177/2325967117702126. eCollection 2017 Apr.

BACKGROUND: Variations in scapular morphology have been associated with the development of atraumatic rotator cuff tears (RCTs). The critical shoulder angle (CSA) accounts for both glenoid inclination and lateral extension of the acromion. The impact of the CSA on...

Spin-Based Mach-Zehnder Interferometry in Topological Insulator p-n Junctions.

Physical review letters

Ilan R, de Juan F, Moore JE.
PMID: 26371673
Phys Rev Lett. 2015 Aug 28;115(9):096802. doi: 10.1103/PhysRevLett.115.096802. Epub 2015 Aug 28.

Transport in three-dimensional topological insulators relies on the existence of a spin-momentum locked surface state that encloses the insulating bulk. In this work we show how, in a topological insulator p-n junction, a magnetic field turns this surface state...

Characterization of Tetracyanopyridine (TCNPy)-Based Magnets: V[TCNPy]2 ⋅z (CH2 Cl2 ) (Tc =111 K) and V[TCNPy]3 ⋅z (CH2 Cl2 ) (Tc =90 K).

Chemistry (Weinheim an der Bergstrasse, Germany)

Hao J, Davidson RA, Kareis CM, Kavand M, van Schooten KJ, Boehme C, Wöß E, Knör G, Miller JS.
PMID: 27529664
Chemistry. 2016 Sep 26;22(40):14273-8. doi: 10.1002/chem.201602385. Epub 2016 Aug 16.

The reaction of 2,3,5,6-tetracyanopyridine (TCNPy) with V(CO)6 in CH2 Cl2 forms new organic-based magnets of V[TCNPy]x ⋅z (CH2 Cl2 ) (x=2, 3) composition. Analysis of the IR spectra suggests that the TCNPy is reduced and coordinated to V(II) sites...

Safety, pharmacokinetics, and pharmacodynamics of oral omaveloxolone (RTA 408), a synthetic triterpenoid, in a first-in-human trial of patients with advanced solid tumors.

OncoTargets and therapy

Creelan BC, Gabrilovich DI, Gray JE, Williams CC, Tanvetyanon T, Haura EB, Weber JS, Gibney GT, Markowitz J, Proksch JW, Reisman SA, McKee MD, Chin MP, Meyer CJ, Antonia SJ.
PMID: 28919776
Onco Targets Ther. 2017 Aug 29;10:4239-4250. doi: 10.2147/OTT.S136992. eCollection 2017.

BACKGROUND: Omaveloxolone is a semisynthetic oleanane triterpenoid that potently activates Nrf2 with subsequent antioxidant function. We conducted a first-in-human Phase I clinical trial (NCT02029729) with the primary objectives to determine the appropriate dose for Phase II studies, characterize pharmacokinetic...

Correction for Pedersen et al., Regulation of CARD11 Signaling and Lymphoma Cell Survival by the E3 Ubiquitin Ligase RNF181.

Molecular and cellular biology

Pedersen SM, Chan W, Jattani RP, Mackie dS, Pomerantz JL.
PMID: 27034408
Mol Cell Biol. 2016 Mar 31;36(8):1322. doi: 10.1128/MCB.00106-16. Print 2016 Apr.

No abstract available.

The Hairpin Furans: Easily Prepared Hybrids of Helicenes and Twisted Acenes.

Angewandte Chemie (International ed. in English)

Geng X, Donahue JP, Mague JT, Pascal RA.
PMID: 26403622
Angew Chem Int Ed Engl. 2015 Nov 16;54(47):13957-60. doi: 10.1002/anie.201506792. Epub 2015 Sep 25.

The thermal reaction of a cyclopentadienone with 6,6'-dimethoxy-5,5'-binaphthoquinone gives, in a single step, a molecular ribbon consisting of two twisted aromatic systems fused to a heteropentahelicene. Such molecules constitute a new class of chiral polycyclic aromatic compounds, the "hairpin...

Showing 13 to 24 of 5635 entries