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Fluxomics of the eastern oyster for environmental stress studies.

Metabolites

Tikunov AP, Stoskopf MK, Macdonald JM.
PMID: 24958387
Metabolites. 2014 Jan 07;4(1):53-70. doi: 10.3390/metabo4010053.

The metabolism of 2-13C/15N-glycine and U-13C-glucose was determined in four tissue blocks (adductor muscle, stomach and digestive gland, mantle, and gills) of the Eastern oyster (Crassostrea virginica) using proton (1H) and carbon-13 (13C) nuclear magnetic resonance (NMR) spectroscopy. The...

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Tikunov AP, Stoskopf MK, Macdonald JM. Fluxomics of the eastern oyster for environmental stress studies. Metabolites. 2014;4(1):53-70doi: 10.3390/metabo4010053.
Tikunov, A. P., Stoskopf, M. K., & Macdonald, J. M. (2014). Fluxomics of the eastern oyster for environmental stress studies. Metabolites, 4(1), 53-70. https://doi.org/10.3390/metabo4010053
Tikunov, Andrey P, et al. "Fluxomics of the eastern oyster for environmental stress studies." Metabolites vol. 4,1 (2014): 53-70. doi: https://doi.org/10.3390/metabo4010053
Tikunov AP, Stoskopf MK, Macdonald JM. Fluxomics of the eastern oyster for environmental stress studies. Metabolites. 2014 Jan 07;4(1):53-70. doi: 10.3390/metabo4010053. PMID: 24958387; PMCID: PMC4018674.
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Discovery of a Potent Parenterally Administered Factor XIa Inhibitor with Hydroxyquinolin-2(1H)-one as the P2' Moiety.

ACS medicinal chemistry letters

Hu Z, Wong PC, Gilligan PJ, Han W, Pabbisetty KB, Bozarth JM, Crain EJ, Harper T, Luettgen JM, Myers JE, Ramamurthy V, Rossi KA, Sheriff S, Watson CA, Wei A, Zheng JJ, Seiffert DA, Wexler RR, Quan ML.
PMID: 26005539
ACS Med Chem Lett. 2015 Apr 08;6(5):590-5. doi: 10.1021/acsmedchemlett.5b00066. eCollection 2015 May 14.

Structure-activity relationship optimization of phenylalanine P1' and P2' regions with a phenylimidazole core resulted in a series of potent FXIa inhibitors. Introducing 4-hydroxyquinolin-2-one as the P2' group enhanced FXIa affinity and metabolic stability. Incorporation of an N-methyl piperazine amide...

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Hu Z, Wong PC, Gilligan PJ, et al. Discovery of a Potent Parenterally Administered Factor XIa Inhibitor with Hydroxyquinolin-2(1H)-one as the P2' Moiety. ACS Med Chem Lett. 2015;6(5):590-5doi: 10.1021/acsmedchemlett.5b00066.
Hu, Z., Wong, P. C., Gilligan, P. J., Han, W., Pabbisetty, K. B., Bozarth, J. M., Crain, E. J., Harper, T., Luettgen, J. M., Myers, J. E., Ramamurthy, V., Rossi, K. A., Sheriff, S., Watson, C. A., Wei, A., Zheng, J. J., Seiffert, D. A., Wexler, R. R., & Quan, M. L. (2015). Discovery of a Potent Parenterally Administered Factor XIa Inhibitor with Hydroxyquinolin-2(1H)-one as the P2' Moiety. ACS medicinal chemistry letters, 6(5), 590-5. https://doi.org/10.1021/acsmedchemlett.5b00066
Hu, Zilun, et al. "Discovery of a Potent Parenterally Administered Factor XIa Inhibitor with Hydroxyquinolin-2(1H)-one as the P2' Moiety." ACS medicinal chemistry letters vol. 6,5 (2015): 590-5. doi: https://doi.org/10.1021/acsmedchemlett.5b00066
Hu Z, Wong PC, Gilligan PJ, Han W, Pabbisetty KB, Bozarth JM, Crain EJ, Harper T, Luettgen JM, Myers JE, Ramamurthy V, Rossi KA, Sheriff S, Watson CA, Wei A, Zheng JJ, Seiffert DA, Wexler RR, Quan ML. Discovery of a Potent Parenterally Administered Factor XIa Inhibitor with Hydroxyquinolin-2(1H)-one as the P2' Moiety. ACS Med Chem Lett. 2015 Apr 08;6(5):590-5. doi: 10.1021/acsmedchemlett.5b00066. eCollection 2015 May 14. PMID: 26005539; PMCID: PMC4434461.
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DEDUCE Clinical Text: An Ontology-based Module to Support Self-Service Clinical Notes Exploration and Cohort Development.

AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science

Roth C, Rusincovitch SA, Horvath MM, Brinson S, Evans S, Shang HC, Ferranti JM.
PMID: 24303270
AMIA Jt Summits Transl Sci Proc. 2013 Mar 18;2013:227. eCollection 2013.

Large amounts of information, as well as opportunities for informing research, education, and operations, are contained within clinical text such as radiology reports and pathology reports. However, this content is less accessible and harder to leverage than structured, discrete...

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Roth C, Rusincovitch SA, Horvath MM, et al. DEDUCE Clinical Text: An Ontology-based Module to Support Self-Service Clinical Notes Exploration and Cohort Development. AMIA Jt Summits Transl Sci Proc. 2013;2013:227
Roth, C., Rusincovitch, S. A., Horvath, M. M., Brinson, S., Evans, S., Shang, H. C., & Ferranti, J. M. (2013). DEDUCE Clinical Text: An Ontology-based Module to Support Self-Service Clinical Notes Exploration and Cohort Development. AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science, 2013227.
Roth, Christopher, et al. "DEDUCE Clinical Text: An Ontology-based Module to Support Self-Service Clinical Notes Exploration and Cohort Development." AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science vol. 2013 (2013): 227.
Roth C, Rusincovitch SA, Horvath MM, Brinson S, Evans S, Shang HC, Ferranti JM. DEDUCE Clinical Text: An Ontology-based Module to Support Self-Service Clinical Notes Exploration and Cohort Development. AMIA Jt Summits Transl Sci Proc. 2013 Mar 18;2013:227. eCollection 2013. PMID: 24303270.
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Hydrodynamically driven colloidal assembly in dip coating.

Physical review letters

Colosqui CE, Morris JF, Stone HA.
PMID: 23683248
Phys Rev Lett. 2013 May 03;110(18):188302. doi: 10.1103/PhysRevLett.110.188302. Epub 2013 Apr 30.

We study the hydrodynamics of dip coating from a suspension and report a mechanism for colloidal assembly and pattern formation on smooth substrates. Below a critical withdrawal speed where the coating film is thinner than the particle diameter, capillary...

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Colosqui CE, Morris JF, Stone HA. Hydrodynamically driven colloidal assembly in dip coating. Phys Rev Lett. 2013;110(18):188302doi: 10.1103/PhysRevLett.110.188302.
Colosqui, C. E., Morris, J. F., & Stone, H. A. (2013). Hydrodynamically driven colloidal assembly in dip coating. Physical review letters, 110(18), 188302. https://doi.org/10.1103/PhysRevLett.110.188302
Colosqui, Carlos E, et al. "Hydrodynamically driven colloidal assembly in dip coating." Physical review letters vol. 110,18 (2013): 188302. doi: https://doi.org/10.1103/PhysRevLett.110.188302
Colosqui CE, Morris JF, Stone HA. Hydrodynamically driven colloidal assembly in dip coating. Phys Rev Lett. 2013 May 03;110(18):188302. doi: 10.1103/PhysRevLett.110.188302. Epub 2013 Apr 30. PMID: 23683248.
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Novel opportunities for CFTR-targeting drug development using organoids.

Rare diseases (Austin, Tex.)

Dekkers JF, van der Ent CK, Beekman JM.
PMID: 25003014
Rare Dis. 2013 Nov 11;1:e27112. doi: 10.4161/rdis.27112. eCollection 2013.

Cystic fibrosis (CF) is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. CFTR mutations lead to production of non-functional CFTR, reduced amounts of normal functioning CFTR or misfolded CFTR with defects in trafficking or function....

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Dekkers JF, van der Ent CK, Beekman JM. Novel opportunities for CFTR-targeting drug development using organoids. Rare Dis. 2013;1:e27112doi: 10.4161/rdis.27112.
Dekkers, J. F., van der Ent, C. K., & Beekman, J. M. (2013). Novel opportunities for CFTR-targeting drug development using organoids. Rare diseases (Austin, Tex.), 1e27112. https://doi.org/10.4161/rdis.27112
Dekkers, Johanna F, et al. "Novel opportunities for CFTR-targeting drug development using organoids." Rare diseases (Austin, Tex.) vol. 1 (2013): e27112. doi: https://doi.org/10.4161/rdis.27112
Dekkers JF, van der Ent CK, Beekman JM. Novel opportunities for CFTR-targeting drug development using organoids. Rare Dis. 2013 Nov 11;1:e27112. doi: 10.4161/rdis.27112. eCollection 2013. PMID: 25003014; PMCID: PMC3915567.
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[No title available]

Journal of clinical outcomes management : JCOM

Keegan MB, Diedrich JT, Peipert JF.
PMID: 25554725
J Clin Outcomes Manag. 2014 Jan;21(1):30-38.

CONCLUSION: Current screening recommendations are not being implemented satisfactorily. Home-based methods of screening are acceptable and may improve universal screening rates.

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Keegan MB, Diedrich JT, Peipert JF. . J Clin Outcomes Manag. 2014;21(1):30-38
Keegan, M. B., Diedrich, J. T., & Peipert, J. F. (2014). . Journal of clinical outcomes management : JCOM, 21(1), 30-38.
Keegan, Mary B, et al. "." Journal of clinical outcomes management : JCOM vol. 21,1 (2014): 30-38.
Keegan MB, Diedrich JT, Peipert JF. . J Clin Outcomes Manag. 2014 Jan;21(1):30-38. PMID: 25554725; PMCID: PMC4279217.
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Connecting at-risk inpatient asthmatics to a community-based program to reduce home environmental risks: care system redesign using quality improvement methods.

Hospital pediatrics

Beck AF, Simmons JM, Sauers HS, Sharkey K, Alam M, Jones C, Kahn RS.
PMID: 24435190
Hosp Pediatr. 2013 Oct;3(4):326-34. doi: 10.1542/hpeds.2013-0047.

INTRODUCTION: Connecting patients admitted with asthma to community-based services could improve care and more efficiently allocate resources. We sought to develop and evaluate an intervention to mitigate in-home environmental hazards (eg, pests, mold) for such children.METHODS: This was a...

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Beck AF, Simmons JM, Sauers HS, et al. Connecting at-risk inpatient asthmatics to a community-based program to reduce home environmental risks: care system redesign using quality improvement methods. Hosp Pediatr. 2013;3(4):326-34doi: 10.1542/hpeds.2013-0047.
Beck, A. F., Simmons, J. M., Sauers, H. S., Sharkey, K., Alam, M., Jones, C., & Kahn, R. S. (2013). Connecting at-risk inpatient asthmatics to a community-based program to reduce home environmental risks: care system redesign using quality improvement methods. Hospital pediatrics, 3(4), 326-34. https://doi.org/10.1542/hpeds.2013-0047
Beck, Andrew F, et al. "Connecting at-risk inpatient asthmatics to a community-based program to reduce home environmental risks: care system redesign using quality improvement methods." Hospital pediatrics vol. 3,4 (2013): 326-34. doi: https://doi.org/10.1542/hpeds.2013-0047
Beck AF, Simmons JM, Sauers HS, Sharkey K, Alam M, Jones C, Kahn RS. Connecting at-risk inpatient asthmatics to a community-based program to reduce home environmental risks: care system redesign using quality improvement methods. Hosp Pediatr. 2013 Oct;3(4):326-34. doi: 10.1542/hpeds.2013-0047. PMID: 24435190.
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Virtual coaching for the high-intensity training of a powerlifter following coronary artery bypass grafting.

Proceedings (Baylor University. Medical Center)

Adams R, Adams J, Qin H, Bilbrey T, Schussler JM.
PMID: 25552808
Proc (Bayl Univ Med Cent). 2015 Jan;28(1):75-7. doi: 10.1080/08998280.2015.11929196.

A 55-year-old powerlifter in Tennessee learned about the sport-specific, high-intensity cardiac rehabilitation training available in Dallas, Texas, and contacted the staff by phone. He was recovering from quadruple coronary artery bypass grafting (CABG) and had completed several weeks of...

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Adams R, Adams J, Qin H, et al. Virtual coaching for the high-intensity training of a powerlifter following coronary artery bypass grafting. Proc (Bayl Univ Med Cent). 2015;28(1):75-7doi: 10.1080/08998280.2015.11929196.
Adams, R., Adams, J., Qin, H., Bilbrey, T., & Schussler, J. M. (2015). Virtual coaching for the high-intensity training of a powerlifter following coronary artery bypass grafting. Proceedings (Baylor University. Medical Center), 28(1), 75-7. https://doi.org/10.1080/08998280.2015.11929196
Adams, Richard, et al. "Virtual coaching for the high-intensity training of a powerlifter following coronary artery bypass grafting." Proceedings (Baylor University. Medical Center) vol. 28,1 (2015): 75-7. doi: https://doi.org/10.1080/08998280.2015.11929196
Adams R, Adams J, Qin H, Bilbrey T, Schussler JM. Virtual coaching for the high-intensity training of a powerlifter following coronary artery bypass grafting. Proc (Bayl Univ Med Cent). 2015 Jan;28(1):75-7. doi: 10.1080/08998280.2015.11929196. PMID: 25552808; PMCID: PMC4264720.
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Seven transmembrane G protein-coupled receptor repertoire of gastric ghrelin cells.

Molecular metabolism

Engelstoft MS, Park WM, Sakata I, Kristensen LV, Husted AS, Osborne-Lawrence S, Piper PK, Walker AK, Pedersen MH, Nøhr MK, Pan J, Sinz CJ, Carrington PE, Akiyama TE, Jones RM, Tang C, Ahmed K, Offermanns S, Egerod KL, Zigman JM, Schwartz TW.
PMID: 24327954
Mol Metab. 2013 Sep 04;2(4):376-92. doi: 10.1016/j.molmet.2013.08.006. eCollection 2013.

The molecular mechanisms regulating secretion of the orexigenic-glucoregulatory hormone ghrelin remain unclear. Based on qPCR analysis of FACS-purified gastric ghrelin cells, highly expressed and enriched 7TM receptors were comprehensively identified and functionally characterized using in vitro, ex vivo and...

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Engelstoft MS, Park WM, Sakata I, et al. Seven transmembrane G protein-coupled receptor repertoire of gastric ghrelin cells. Mol Metab. 2013;2(4):376-92doi: 10.1016/j.molmet.2013.08.006.
Engelstoft, M. S., Park, W. M., Sakata, I., Kristensen, L. V., Husted, A. S., Osborne-Lawrence, S., Piper, P. K., Walker, A. K., Pedersen, M. H., Nøhr, M. K., Pan, J., Sinz, C. J., Carrington, P. E., Akiyama, T. E., Jones, R. M., Tang, C., Ahmed, K., Offermanns, S., Egerod, K. L., Zigman, J. M., & Schwartz, T. W. (2013). Seven transmembrane G protein-coupled receptor repertoire of gastric ghrelin cells. Molecular metabolism, 2(4), 376-92. https://doi.org/10.1016/j.molmet.2013.08.006
Engelstoft, Maja S, et al. "Seven transmembrane G protein-coupled receptor repertoire of gastric ghrelin cells." Molecular metabolism vol. 2,4 (2013): 376-92. doi: https://doi.org/10.1016/j.molmet.2013.08.006
Engelstoft MS, Park WM, Sakata I, Kristensen LV, Husted AS, Osborne-Lawrence S, Piper PK, Walker AK, Pedersen MH, Nøhr MK, Pan J, Sinz CJ, Carrington PE, Akiyama TE, Jones RM, Tang C, Ahmed K, Offermanns S, Egerod KL, Zigman JM, Schwartz TW. Seven transmembrane G protein-coupled receptor repertoire of gastric ghrelin cells. Mol Metab. 2013 Sep 04;2(4):376-92. doi: 10.1016/j.molmet.2013.08.006. eCollection 2013. PMID: 24327954; PMCID: PMC3854997.
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Neoadjuvant Hormonal Therapy is Associated with Comparable Outcomes to Neoadjuvant Chemotherapy in Post-Menopausal Women with Estrogen Receptor-Positive Breast Cancer.

Frontiers in oncology

Marcus DM, Switchenko JM, Prabhu R, O'Regan R, Zelnak A, Fasola C, Mister D, Torres MA.
PMID: 24409418
Front Oncol. 2013 Dec 27;3:317. doi: 10.3389/fonc.2013.00317. eCollection 2013.

OBJECTIVES: We compared outcomes in post-menopausal estrogen receptor-positive (ER+) breast cancer patients treated with neoadjuvant hormonal therapy (NAHT) or neoadjuvant chemotherapy (NACT).METHODS: We retrospectively identified post-menopausal women who received either NAHT or NACT for non-metastatic, non-inflammatory, ER+, Her2neu negative...

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Marcus DM, Switchenko JM, Prabhu R, et al. Neoadjuvant Hormonal Therapy is Associated with Comparable Outcomes to Neoadjuvant Chemotherapy in Post-Menopausal Women with Estrogen Receptor-Positive Breast Cancer. Front Oncol. 2013;3:317doi: 10.3389/fonc.2013.00317.
Marcus, D. M., Switchenko, J. M., Prabhu, R., O'Regan, R., Zelnak, A., Fasola, C., Mister, D., & Torres, M. A. (2013). Neoadjuvant Hormonal Therapy is Associated with Comparable Outcomes to Neoadjuvant Chemotherapy in Post-Menopausal Women with Estrogen Receptor-Positive Breast Cancer. Frontiers in oncology, 3317. https://doi.org/10.3389/fonc.2013.00317
Marcus, David M, et al. "Neoadjuvant Hormonal Therapy is Associated with Comparable Outcomes to Neoadjuvant Chemotherapy in Post-Menopausal Women with Estrogen Receptor-Positive Breast Cancer." Frontiers in oncology vol. 3 (2013): 317. doi: https://doi.org/10.3389/fonc.2013.00317
Marcus DM, Switchenko JM, Prabhu R, O'Regan R, Zelnak A, Fasola C, Mister D, Torres MA. Neoadjuvant Hormonal Therapy is Associated with Comparable Outcomes to Neoadjuvant Chemotherapy in Post-Menopausal Women with Estrogen Receptor-Positive Breast Cancer. Front Oncol. 2013 Dec 27;3:317. doi: 10.3389/fonc.2013.00317. eCollection 2013. PMID: 24409418; PMCID: PMC3873517.
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A Pharmacological Chaperone Molecule Induces Cancer Cell Death by Restoring Tertiary DNA Structures in Mutant hTERT Promoters.

Journal of the American Chemical Society

Kang HJ, Cui Y, Yin H, Scheid A, Hendricks WPD, Schmidt J, Sekulic A, Kong D, Trent JM, Gokhale V, Mao H, Hurley LH.
PMID: 27643954
J Am Chem Soc. 2016 Oct 19;138(41):13673-13692. doi: 10.1021/jacs.6b07598. Epub 2016 Oct 05.

Activation of human telomerase reverse transcriptase (hTERT) is necessary for limitless replication in tumorigenesis. Whereas hTERT is transcriptionally silenced in normal cells, most tumor cells reactivate hTERT expression by alleviating transcriptional repression through diverse genetic and epigenetic mechanisms. Transcription-activating...

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Kang HJ, Cui Y, Yin H, et al. A Pharmacological Chaperone Molecule Induces Cancer Cell Death by Restoring Tertiary DNA Structures in Mutant hTERT Promoters. J Am Chem Soc. 2016;138(41):13673-13692doi: 10.1021/jacs.6b07598.
Kang, H. J., Cui, Y., Yin, H., Scheid, A., Hendricks, W. P. D., Schmidt, J., Sekulic, A., Kong, D., Trent, J. M., Gokhale, V., Mao, H., & Hurley, L. H. (2016). A Pharmacological Chaperone Molecule Induces Cancer Cell Death by Restoring Tertiary DNA Structures in Mutant hTERT Promoters. Journal of the American Chemical Society, 138(41), 13673-13692. https://doi.org/10.1021/jacs.6b07598
Kang, Hyun-Jin, et al. "A Pharmacological Chaperone Molecule Induces Cancer Cell Death by Restoring Tertiary DNA Structures in Mutant hTERT Promoters." Journal of the American Chemical Society vol. 138,41 (2016): 13673-13692. doi: https://doi.org/10.1021/jacs.6b07598
Kang HJ, Cui Y, Yin H, Scheid A, Hendricks WPD, Schmidt J, Sekulic A, Kong D, Trent JM, Gokhale V, Mao H, Hurley LH. A Pharmacological Chaperone Molecule Induces Cancer Cell Death by Restoring Tertiary DNA Structures in Mutant hTERT Promoters. J Am Chem Soc. 2016 Oct 19;138(41):13673-13692. doi: 10.1021/jacs.6b07598. Epub 2016 Oct 05. PMID: 27643954.
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Reconsidering Depression in the Elderly.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

Caine ED, Lyness JM, King DA.
PMID: 28530945
Am J Geriatr Psychiatry. 1993 Winter;1(1):4-20. doi: 10.1097/00019442-199300110-00003. Epub 2013 Jan 28.

The authors present a literature review and a scientific commentary. The prevalence of depressive disorders in the elderly and their association with significant morbidity and mortality are discussed in relation to study of clinical heterogeneity, which may provide useful...

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Caine ED, Lyness JM, King DA. Reconsidering Depression in the Elderly. Am J Geriatr Psychiatry. 2013;1(1):4-20doi: 10.1097/00019442-199300110-00003.
Caine, E. D., Lyness, J. M., & King, D. A. (1993). Reconsidering Depression in the Elderly. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 1(1), 4-20. https://doi.org/10.1097/00019442-199300110-00003
Caine, Eric D, et al. "Reconsidering Depression in the Elderly." The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry vol. 1,1 (1993): 4-20. doi: https://doi.org/10.1097/00019442-199300110-00003
Caine ED, Lyness JM, King DA. Reconsidering Depression in the Elderly. Am J Geriatr Psychiatry. 1993 Winter;1(1):4-20. doi: 10.1097/00019442-199300110-00003. Epub 2013 Jan 28. PMID: 28530945.
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Showing 25 to 36 of 2638 entries