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Showing 265 to 266 of 266 entries
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Heterocellular OSM-OSMR signalling reprograms fibroblasts to promote pancreatic cancer growth and metastasis.

Nature communications

Lee BY, Hogg EKJ, Below CR, Kononov A, Blanco-Gomez A, Heider F, Xu J, Hutton C, Zhang X, Scheidt T, Beattie K, Lamarca A, McNamara M, Valle JW, Jørgensen C.
PMID: 34921158
Nat Commun. 2021 Dec 17;12(1):7336. doi: 10.1038/s41467-021-27607-8.

Pancreatic ductal adenocarcinoma (PDA) is a lethal malignancy with a complex microenvironment. Dichotomous tumour-promoting and -restrictive roles have been ascribed to the tumour microenvironment, however the effects of individual stromal subsets remain incompletely characterised. Here, we describe how heterocellular...

Enhanced hyperspectral tomography for bioimaging by spatiospectral reconstruction.

Scientific reports

Warr R, Ametova E, Cernik RJ, Fardell G, Handschuh S, Jørgensen JS, Papoutsellis E, Pasca E, Withers PJ.
PMID: 34675228
Sci Rep. 2021 Oct 21;11(1):20818. doi: 10.1038/s41598-021-00146-4.

Here we apply hyperspectral bright field imaging to collect computed tomographic images with excellent energy resolution (~ 1 keV), applying it for the first time to map the distribution of stain in a fixed biological sample through its characteristic...

Showing 265 to 266 of 266 entries