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Showing 709 to 715 of 715 entries
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Fragment-based lead discovery to identify novel inhibitors that target the ATP binding site of pyruvate dehydrogenase kinases.

Bioorganic & medicinal chemistry

Akaki T, Bessho Y, Ito T, Fujioka S, Ubukata M, Mori G, Yamanaka K, Orita T, Doi S, Iwanaga T, Ikegashira K, Hantani Y, Nakanishi I, Adachi T.
PMID: 34274549
Bioorg Med Chem. 2021 Aug 15;44:116283. doi: 10.1016/j.bmc.2021.116283. Epub 2021 Jul 08.

A fragment-based lead discovery approach was applied to Pyruvate Dehydrogenase Kinases (PDHKs) to discover inhibitors against the ATP binding site with novel chemotypes. X-ray fragment screening toward PDHK4 provided a fragment hit 1 with a characteristic interaction in a...

What Kind of Intervention Is Effective for Improving Subjective Well-Being Among Workers? A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Frontiers in psychology

Sakuraya A, Imamura K, Watanabe K, Asai Y, Ando E, Eguchi H, Nishida N, Kobayashi Y, Arima H, Iwanaga M, Otsuka Y, Sasaki N, Inoue A, Inoue R, Tsuno K, Hino A, Shimazu A, Tsutsumi A, Kawakami N.
PMID: 33281653
Front Psychol. 2020 Nov 13;11:528656. doi: 10.3389/fpsyg.2020.528656. eCollection 2020.

No abstract available.

An unusual location of the ansa cervicalis.

Morphologie : bulletin de l'Association des anatomistes

Ogata K, Iwanaga J, Decater T, Loukas M, Tubbs RS.
PMID: 33358105
Morphologie. 2020 Dec 21; doi: 10.1016/j.morpho.2020.11.010. Epub 2020 Dec 21.

The ansa cervicalis (AC) is part of the cervical plexus and is formed by the ventral rami of spinal nerves C1-C3. It is usually formed by two roots that run parallel to each other and then form a loop...

A rare anatomical variation of the submental artery.

Surgical and radiologic anatomy : SRA

Masui M, Ibaragi S, Okui T, Tubbs RS, Iwanaga J.
PMID: 34510248
Surg Radiol Anat. 2021 Nov;43(11):1805-1808. doi: 10.1007/s00276-021-02830-6. Epub 2021 Sep 12.

The submental artery usually runs anteriorly on the inferior surface of the mylohyoid muscle, giving branches to that muscle and to the anterior belly of the digastric muscle, finally supplying the submental skin. Branches of it often perforate the...

Correction to: Clinical and Immunological Heterogeneity in Japanese Patients with Gain-of-Function Variants in STAT3.

Journal of clinical immunology

Tanita K, Sakura F, Nambu R, Tsumura M, Imanaka Y, Ohnishi H, Kato Z, Pan J, Hoshino A, Suzuki K, Yasutomi M, Umetsu S, Okada C, Takagi M, Imai K, Ohara O, Muise AM, Okada S, Morio T, Kanegane H.
PMID: 33694042
J Clin Immunol. 2021 May;41(4):791-794. doi: 10.1007/s10875-021-01014-6.

No abstract available.

Nutritional assessments for ordinary medical care in patients with chronic liver disease.

Hepatology research : the official journal of the Japan Society of Hepatology

Taniguchi E, Kawaguchi T, Otsuka M, Uchida Y, Nagamatsu A, Itou M, Oriishi T, Ishii K, Imanaga M, Suetsugu T, Otsuyama J, Ibi R, Ono M, Tanaka S, Sata M.
PMID: 22827610
Hepatol Res. 2013 Feb;43(2):192-9. doi: 10.1111/j.1872-034X.2012.01055.x. Epub 2012 Jul 25.

AIM:   In patients with chronic liver disease who are at risk of malnutrition, simple and useful assessments for nutritional status should be established for ordinary medical care. The prognostic nutritional index (PNI) and controlling nutritional status (CONUT) are simple...

What are the retromolar and bifid/trifid mandibular canals as seen on cone-beam computed tomography? Revisiting classic gross anatomy of the inferior alveolar nerve and correcting terminology.

Surgical and radiologic anatomy : SRA

Iwanaga J, Takeshita Y, Matsushita Y, Hur MS, Ibaragi S, Tubbs RS.
PMID: 34854962
Surg Radiol Anat. 2022 Jan;44(1):147-156. doi: 10.1007/s00276-021-02862-y. Epub 2021 Dec 02.

PURPOSE: Since cone-beam computed tomography was developed, a number of radiological studies on the bifid mandibular canals (BMCs) and trifid mandibular canals (TMCs) have been reported. However, many of the suggested subtypes of the BMC described in the literature...

Showing 709 to 715 of 715 entries