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The Ceramide Synthase Subunit Lac1 Regulates Cell Growth and Size in Fission Yeast.

International journal of molecular sciences

Flor-Parra I, Sabido-Bozo S, Ikeda A, Hanaoka K, Aguilera-Romero A, Funato K, Muñiz M, Lucena R.
PMID: 35008733
Int J Mol Sci. 2021 Dec 28;23(1). doi: 10.3390/ijms23010303.

Cell division produces two viable cells of a defined size. Thus, all cells require mechanisms to measure growth and trigger cell division when sufficient growth has occurred. Previous data suggest a model in which growth rate and cell size...

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Flor-Parra I, Sabido-Bozo S, Ikeda A, et al. The Ceramide Synthase Subunit Lac1 Regulates Cell Growth and Size in Fission Yeast. Int J Mol Sci. 2021;23(1)doi: 10.3390/ijms23010303.
Flor-Parra, I., Sabido-Bozo, S., Ikeda, A., Hanaoka, K., Aguilera-Romero, A., Funato, K., Muñiz, M., & Lucena, R. (2021). The Ceramide Synthase Subunit Lac1 Regulates Cell Growth and Size in Fission Yeast. International journal of molecular sciences, 23(1), . https://doi.org/10.3390/ijms23010303
Flor-Parra, Ignacio, et al. "The Ceramide Synthase Subunit Lac1 Regulates Cell Growth and Size in Fission Yeast." International journal of molecular sciences vol. 23,1 (2021). doi: https://doi.org/10.3390/ijms23010303
Flor-Parra I, Sabido-Bozo S, Ikeda A, Hanaoka K, Aguilera-Romero A, Funato K, Muñiz M, Lucena R. The Ceramide Synthase Subunit Lac1 Regulates Cell Growth and Size in Fission Yeast. Int J Mol Sci. 2021 Dec 28;23(1). doi: 10.3390/ijms23010303. PMID: 35008733.
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The Alopecia Areata Phenotype Is Induced by the Water Avoidance Stress Test In .

Biomedicines

Zhao Q, Koyama S, Yoshihara N, Takagi A, Komiyama E, Wada A, Oka A, Ikeda S.
PMID: 34356904
Biomedicines. 2021 Jul 19;9(7). doi: 10.3390/biomedicines9070840.

We recently discovered a nonsynonymous variant in the coiled-coil alpha-helical rod protein 1 (

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Zhao Q, Koyama S, Yoshihara N, et al. The Alopecia Areata Phenotype Is Induced by the Water Avoidance Stress Test In . Biomedicines. 2021;9(7)doi: 10.3390/biomedicines9070840.
Zhao, Q., Koyama, S., Yoshihara, N., Takagi, A., Komiyama, E., Wada, A., Oka, A., & Ikeda, S. (2021). The Alopecia Areata Phenotype Is Induced by the Water Avoidance Stress Test In . Biomedicines, 9(7), . https://doi.org/10.3390/biomedicines9070840
Zhao, Qiaofeng, et al. "The Alopecia Areata Phenotype Is Induced by the Water Avoidance Stress Test In ." Biomedicines vol. 9,7 (2021). doi: https://doi.org/10.3390/biomedicines9070840
Zhao Q, Koyama S, Yoshihara N, Takagi A, Komiyama E, Wada A, Oka A, Ikeda S. The Alopecia Areata Phenotype Is Induced by the Water Avoidance Stress Test In . Biomedicines. 2021 Jul 19;9(7). doi: 10.3390/biomedicines9070840. PMID: 34356904; PMCID: PMC8301465.
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Identifying Issues in Fertility Preservation for Childhood and Adolescent Patients with Cancer at Pediatric Oncology Hospitals in Japan.

Journal of adolescent and young adult oncology

Maezawa T, Suzuki N, Takeuchi H, Kiyotani C, Amano K, Keino D, Okimura H, Miyachi M, Goto M, Takae S, Horie A, Takita J, Sago H, Hirayama M, Ikeda T, Matsumoto K.
PMID: 34297622
J Adolesc Young Adult Oncol. 2021 Jul 22; doi: 10.1089/jayao.2021.0088. Epub 2021 Jul 22.

No abstract available.

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Maezawa T, Suzuki N, Takeuchi H, et al. Identifying Issues in Fertility Preservation for Childhood and Adolescent Patients with Cancer at Pediatric Oncology Hospitals in Japan. J Adolesc Young Adult Oncol. 2021;doi: 10.1089/jayao.2021.0088.
Maezawa, T., Suzuki, N., Takeuchi, H., Kiyotani, C., Amano, K., Keino, D., Okimura, H., Miyachi, M., Goto, M., Takae, S., Horie, A., Takita, J., Sago, H., Hirayama, M., Ikeda, T., & Matsumoto, K. (2021). Identifying Issues in Fertility Preservation for Childhood and Adolescent Patients with Cancer at Pediatric Oncology Hospitals in Japan. Journal of adolescent and young adult oncology, . https://doi.org/10.1089/jayao.2021.0088
Maezawa, Tadashi, et al. "Identifying Issues in Fertility Preservation for Childhood and Adolescent Patients with Cancer at Pediatric Oncology Hospitals in Japan." Journal of adolescent and young adult oncology vol. (2021). doi: https://doi.org/10.1089/jayao.2021.0088
Maezawa T, Suzuki N, Takeuchi H, Kiyotani C, Amano K, Keino D, Okimura H, Miyachi M, Goto M, Takae S, Horie A, Takita J, Sago H, Hirayama M, Ikeda T, Matsumoto K. Identifying Issues in Fertility Preservation for Childhood and Adolescent Patients with Cancer at Pediatric Oncology Hospitals in Japan. J Adolesc Young Adult Oncol. 2021 Jul 22; doi: 10.1089/jayao.2021.0088. Epub 2021 Jul 22. PMID: 34297622.
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Enhanced fusogenicity and pathogenicity of SARS-CoV-2 Delta P681R mutation.

Nature

Saito A, Irie T, Suzuki R, Maemura T, Nasser H, Uriu K, Kosugi Y, Shirakawa K, Sadamasu K, Kimura I, Ito J, Wu J, Iwatsuki-Horimoto K, Ito M, Yamayoshi S, Loeber S, Tsuda M, Wang L, Ozono S, Butlertanaka EP, Tanaka YL, Shimizu R, Shimizu K, Yoshimatsu K, Kawabata R, Sakaguchi T, Tokunaga K, Yoshida I, Asakura H, Nagashima M, Kazuma Y, Nomura R, Horisawa Y, Yoshimura K, Takaori-Kondo A, Imai M, Tanaka S, Nakagawa S, Ikeda T, Fukuhara T, Kawaoka Y, Sato K.
PMID: 34823256
Nature. 2021 Nov 25; doi: 10.1038/s41586-021-04266-9. Epub 2021 Nov 25.

During the current coronavirus disease 2019 (COVID-19) pandemic, a variety of mutations have accumulated in the viral genome of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and, at the time of writing, four variants of concern are considered to...

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Saito A, Irie T, Suzuki R, et al. Enhanced fusogenicity and pathogenicity of SARS-CoV-2 Delta P681R mutation. Nature. 2021;doi: 10.1038/s41586-021-04266-9.
Saito, A., Irie, T., Suzuki, R., Maemura, T., Nasser, H., Uriu, K., Kosugi, Y., Shirakawa, K., Sadamasu, K., Kimura, I., Ito, J., Wu, J., Iwatsuki-Horimoto, K., Ito, M., Yamayoshi, S., Loeber, S., Tsuda, M., Wang, L., Ozono, S., Butlertanaka, E. P., Tanaka, Y. L., Shimizu, R., Shimizu, K., Yoshimatsu, K., Kawabata, R., Sakaguchi, T., Tokunaga, K., Yoshida, I., Asakura, H., Nagashima, M., Kazuma, Y., Nomura, R., Horisawa, Y., Yoshimura, K., Takaori-Kondo, A., Imai, M., Tanaka, S., Nakagawa, S., Ikeda, T., Fukuhara, T., Kawaoka, Y., & Sato, K. (2021). Enhanced fusogenicity and pathogenicity of SARS-CoV-2 Delta P681R mutation. Nature, . https://doi.org/10.1038/s41586-021-04266-9
Saito, Akatsuki, et al. "Enhanced fusogenicity and pathogenicity of SARS-CoV-2 Delta P681R mutation." Nature vol. (2021). doi: https://doi.org/10.1038/s41586-021-04266-9
Saito A, Irie T, Suzuki R, Maemura T, Nasser H, Uriu K, Kosugi Y, Shirakawa K, Sadamasu K, Kimura I, Ito J, Wu J, Iwatsuki-Horimoto K, Ito M, Yamayoshi S, Loeber S, Tsuda M, Wang L, Ozono S, Butlertanaka EP, Tanaka YL, Shimizu R, Shimizu K, Yoshimatsu K, Kawabata R, Sakaguchi T, Tokunaga K, Yoshida I, Asakura H, Nagashima M, Kazuma Y, Nomura R, Horisawa Y, Yoshimura K, Takaori-Kondo A, Imai M, Tanaka S, Nakagawa S, Ikeda T, Fukuhara T, Kawaoka Y, Sato K. Enhanced fusogenicity and pathogenicity of SARS-CoV-2 Delta P681R mutation. Nature. 2021 Nov 25; doi: 10.1038/s41586-021-04266-9. Epub 2021 Nov 25. PMID: 34823256.
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COVID-19 and adult-onset Still's disease as part of hyperferritinemic syndromes.

Modern rheumatology case reports

Kawasaki T, Ooka S, Mizushima M, Nakamura Y, Ikeda H, Sakurada T, Suzuki S, Yamazaki K, Goto Y, Sakurai K, Yukitaka Y, Kiyokawa T, Tonooka K, Kunishima H, Kawahata K.
PMID: 34592766
Mod Rheumatol Case Rep. 2022 Jan 07;6(1):101-105. doi: 10.1093/mrcr/rxab032.

The coronavirus disease (COVID-19) is known to cause hyperferritinemia and haemophagocytic lymphohistiocytosis. Including this laboratory parameter, symptoms similar to COVID-19 have been observed in adult-onset Still's disease (AOSD), catastrophic antiphospholipid syndrome, macrophage activation syndrome, and septic shock, which has...

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Kawasaki T, Ooka S, Mizushima M, et al. COVID-19 and adult-onset Still's disease as part of hyperferritinemic syndromes. Mod Rheumatol Case Rep. 2022;6(1):101-105doi: 10.1093/mrcr/rxab032.
Kawasaki, T., Ooka, S., Mizushima, M., Nakamura, Y., Ikeda, H., Sakurada, T., Suzuki, S., Yamazaki, K., Goto, Y., Sakurai, K., Yukitaka, Y., Kiyokawa, T., Tonooka, K., Kunishima, H., & Kawahata, K. (2022). COVID-19 and adult-onset Still's disease as part of hyperferritinemic syndromes. Modern rheumatology case reports, 6(1), 101-105. https://doi.org/10.1093/mrcr/rxab032
Kawasaki, Tatsuya, et al. "COVID-19 and adult-onset Still's disease as part of hyperferritinemic syndromes." Modern rheumatology case reports vol. 6,1 (2022): 101-105. doi: https://doi.org/10.1093/mrcr/rxab032
Kawasaki T, Ooka S, Mizushima M, Nakamura Y, Ikeda H, Sakurada T, Suzuki S, Yamazaki K, Goto Y, Sakurai K, Yukitaka Y, Kiyokawa T, Tonooka K, Kunishima H, Kawahata K. COVID-19 and adult-onset Still's disease as part of hyperferritinemic syndromes. Mod Rheumatol Case Rep. 2022 Jan 07;6(1):101-105. doi: 10.1093/mrcr/rxab032. PMID: 34592766; PMCID: PMC8500156.
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miR-106a-363 cluster in extracellular vesicles promotes endogenous myocardial repair via Notch3 pathway in ischemic heart injury.

Basic research in cardiology

Jung JH, Ikeda G, Tada Y, von Bornstädt D, Santoso MR, Wahlquist C, Rhee S, Jeon YJ, Yu AC, O'brien CG, Red-Horse K, Appel EA, Mercola M, Woo J, Yang PC.
PMID: 33742276
Basic Res Cardiol. 2021 Mar 19;116(1):19. doi: 10.1007/s00395-021-00858-8.

Endogenous capability of the post-mitotic human heart holds great promise to restore the injured myocardium. Recent evidence indicates that the extracellular vesicles (EVs) regulate cardiac homeostasis and regeneration. Here, we investigated the molecular mechanism of EVs for self-repair. We...

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Jung JH, Ikeda G, Tada Y, et al. miR-106a-363 cluster in extracellular vesicles promotes endogenous myocardial repair via Notch3 pathway in ischemic heart injury. Basic Res Cardiol. 2021;116(1):19doi: 10.1007/s00395-021-00858-8.
Jung, J. H., Ikeda, G., Tada, Y., von Bornstädt, D., Santoso, M. R., Wahlquist, C., Rhee, S., Jeon, Y. J., Yu, A. C., O'brien, C. G., Red-Horse, K., Appel, E. A., Mercola, M., Woo, J., & Yang, P. C. (2021). miR-106a-363 cluster in extracellular vesicles promotes endogenous myocardial repair via Notch3 pathway in ischemic heart injury. Basic research in cardiology, 116(1), 19. https://doi.org/10.1007/s00395-021-00858-8
Jung, Ji-Hye, et al. "miR-106a-363 cluster in extracellular vesicles promotes endogenous myocardial repair via Notch3 pathway in ischemic heart injury." Basic research in cardiology vol. 116,1 (2021): 19. doi: https://doi.org/10.1007/s00395-021-00858-8
Jung JH, Ikeda G, Tada Y, von Bornstädt D, Santoso MR, Wahlquist C, Rhee S, Jeon YJ, Yu AC, O'brien CG, Red-Horse K, Appel EA, Mercola M, Woo J, Yang PC. miR-106a-363 cluster in extracellular vesicles promotes endogenous myocardial repair via Notch3 pathway in ischemic heart injury. Basic Res Cardiol. 2021 Mar 19;116(1):19. doi: 10.1007/s00395-021-00858-8. PMID: 33742276; PMCID: PMC8601755.
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Role of hyperpolarization-activated cyclic nucleotide-gated channels in aging bladder phenotype.

Life sciences

Singh N, Zabbarova I, Ikeda Y, Kanai A, Chermansky C, Yoshimura N, Tyagi P.
PMID: 34875252
Life Sci. 2021 Dec 04;289:120203. doi: 10.1016/j.lfs.2021.120203. Epub 2021 Dec 04.

OBJECTIVE: To assess the functional role of Hyperpolarization-activated cyclic nucleotide-gated gated channel (HCN) subtypes in the aging bladder phenotype characterized by diminished bladder volume sensation (BVS) with or without the detrusor instability (DI).METHODS: Expression of HCN subtypes was examined...

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Singh N, Zabbarova I, Ikeda Y, et al. Role of hyperpolarization-activated cyclic nucleotide-gated channels in aging bladder phenotype. Life Sci. 2021;289:120203doi: 10.1016/j.lfs.2021.120203.
Singh, N., Zabbarova, I., Ikeda, Y., Kanai, A., Chermansky, C., Yoshimura, N., & Tyagi, P. (2021). Role of hyperpolarization-activated cyclic nucleotide-gated channels in aging bladder phenotype. Life sciences, 289120203. https://doi.org/10.1016/j.lfs.2021.120203
Singh, Nishant, et al. "Role of hyperpolarization-activated cyclic nucleotide-gated channels in aging bladder phenotype." Life sciences vol. 289 (2021): 120203. doi: https://doi.org/10.1016/j.lfs.2021.120203
Singh N, Zabbarova I, Ikeda Y, Kanai A, Chermansky C, Yoshimura N, Tyagi P. Role of hyperpolarization-activated cyclic nucleotide-gated channels in aging bladder phenotype. Life Sci. 2021 Dec 04;289:120203. doi: 10.1016/j.lfs.2021.120203. Epub 2021 Dec 04. PMID: 34875252.
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Photodynamic therapy for pulmonary mucoepidermoid carcinoma.

Respiratory medicine case reports

Kimura M, Miyajima K, Ishikawa R, Yamada Y, Kono T, Okunaka T, Iwaya K, Ikeda N.
PMID: 34401275
Respir Med Case Rep. 2021 May 15;33:101431. doi: 10.1016/j.rmcr.2021.101431. eCollection 2021.

Pulmonary mucoepidermoid carcinoma (PMEC) are rare, accounting for 0.1-0.2% of all malignant lung tumors. Furthermore, endobronchial lesions are rare and are more commonly found in the segmental or lobar bronchi. We present, to the best of our knowledge, the...

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Kimura M, Miyajima K, Ishikawa R, et al. Photodynamic therapy for pulmonary mucoepidermoid carcinoma. Respir Med Case Rep. 2021;33:101431doi: 10.1016/j.rmcr.2021.101431.
Kimura, M., Miyajima, K., Ishikawa, R., Yamada, Y., Kono, T., Okunaka, T., Iwaya, K., & Ikeda, N. (2021). Photodynamic therapy for pulmonary mucoepidermoid carcinoma. Respiratory medicine case reports, 33101431. https://doi.org/10.1016/j.rmcr.2021.101431
Kimura, Masakazu, et al. "Photodynamic therapy for pulmonary mucoepidermoid carcinoma." Respiratory medicine case reports vol. 33 (2021): 101431. doi: https://doi.org/10.1016/j.rmcr.2021.101431
Kimura M, Miyajima K, Ishikawa R, Yamada Y, Kono T, Okunaka T, Iwaya K, Ikeda N. Photodynamic therapy for pulmonary mucoepidermoid carcinoma. Respir Med Case Rep. 2021 May 15;33:101431. doi: 10.1016/j.rmcr.2021.101431. eCollection 2021. PMID: 34401275; PMCID: PMC8348553.
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Deep learning-based model for diagnosing Alzheimer's disease and tauopathies.

Neuropathology and applied neurobiology

Koga S, Ikeda A, Dickson DW.
PMID: 34402107
Neuropathol Appl Neurobiol. 2021 Aug 17; doi: 10.1111/nan.12759. Epub 2021 Aug 17.

AIMS: This study aimed to develop a deep learning-based model for differentiating tauopathies, including Alzheimer's disease (AD), progressive supranuclear palsy (PSP), corticobasal degeneration (CBD) and Pick's disease (PiD), based on tau-immunostained digital slide images.METHODS: We trained the YOLOv3 object...

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Koga S, Ikeda A, Dickson DW. Deep learning-based model for diagnosing Alzheimer's disease and tauopathies. Neuropathol Appl Neurobiol. 2021;doi: 10.1111/nan.12759.
Koga, S., Ikeda, A., & Dickson, D. W. (2021). Deep learning-based model for diagnosing Alzheimer's disease and tauopathies. Neuropathology and applied neurobiology, . https://doi.org/10.1111/nan.12759
Koga, Shunsuke, et al. "Deep learning-based model for diagnosing Alzheimer's disease and tauopathies." Neuropathology and applied neurobiology vol. (2021). doi: https://doi.org/10.1111/nan.12759
Koga S, Ikeda A, Dickson DW. Deep learning-based model for diagnosing Alzheimer's disease and tauopathies. Neuropathol Appl Neurobiol. 2021 Aug 17; doi: 10.1111/nan.12759. Epub 2021 Aug 17. PMID: 34402107.
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MYC-PDL1 axis reduces sensitivity to nivolumab in recurrent head and neck squamous cell carcinoma.

Oral oncology

Noji R, Kano Y, Hirai H, Onishi I, Nishii N, Yoshimura R, Miyake S, Ikeda S, Harada H.
PMID: 34896892
Oral Oncol. 2021 Dec 09;124:105666. doi: 10.1016/j.oraloncology.2021.105666. Epub 2021 Dec 09.

Patients with recurrent or metastatic squamous cell carcinoma of the head and neck (R/M HNSCC) have a poor prognosis. Recently, the use of immune checkpoint inhibitors (ICIs) for drug treatment has been expanding . However, the response rate to...

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Noji R, Kano Y, Hirai H, et al. MYC-PDL1 axis reduces sensitivity to nivolumab in recurrent head and neck squamous cell carcinoma. Oral Oncol. 2021;124:105666doi: 10.1016/j.oraloncology.2021.105666.
Noji, R., Kano, Y., Hirai, H., Onishi, I., Nishii, N., Yoshimura, R., Miyake, S., Ikeda, S., & Harada, H. (2021). MYC-PDL1 axis reduces sensitivity to nivolumab in recurrent head and neck squamous cell carcinoma. Oral oncology, 124105666. https://doi.org/10.1016/j.oraloncology.2021.105666
Noji, Rika, et al. "MYC-PDL1 axis reduces sensitivity to nivolumab in recurrent head and neck squamous cell carcinoma." Oral oncology vol. 124 (2021): 105666. doi: https://doi.org/10.1016/j.oraloncology.2021.105666
Noji R, Kano Y, Hirai H, Onishi I, Nishii N, Yoshimura R, Miyake S, Ikeda S, Harada H. MYC-PDL1 axis reduces sensitivity to nivolumab in recurrent head and neck squamous cell carcinoma. Oral Oncol. 2021 Dec 09;124:105666. doi: 10.1016/j.oraloncology.2021.105666. Epub 2021 Dec 09. PMID: 34896892.
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Showing 4801 to 4810 of 4810 entries