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Heterogeneity of Tau Deposition and Microvascular Involvement in MCI and AD.

Current Alzheimer research

Bryant AG, Manhard MK, Salat DH, Rosen BR, Hyman BT, Johnson KA, Huang S, Bennett RE, Yen YF.
PMID: 34825871
Curr Alzheimer Res. 2021 Nov 25; doi: 10.2174/1567205018666211126113904. Epub 2021 Nov 25.

BACKGROUND: Reduced cerebrovascular function and accumulation of tau pathology are key components of cognitive decline in Alzheimer's disease (AD). Recent multimodal neuroimag- ing studies show a correlation between cortical tau accumulation and reduced cerebral perfusion. However, animal models predict...

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Bryant AG, Manhard MK, Salat DH, et al. Heterogeneity of Tau Deposition and Microvascular Involvement in MCI and AD. Curr Alzheimer Res. 2021;doi: 10.2174/1567205018666211126113904.
Bryant, A. G., Manhard, M. K., Salat, D. H., Rosen, B. R., Hyman, B. T., Johnson, K. A., Huang, S., Bennett, R. E., & Yen, Y. F. (2021). Heterogeneity of Tau Deposition and Microvascular Involvement in MCI and AD. Current Alzheimer research, . https://doi.org/10.2174/1567205018666211126113904
Bryant, Annie G, et al. "Heterogeneity of Tau Deposition and Microvascular Involvement in MCI and AD." Current Alzheimer research vol. (2021). doi: https://doi.org/10.2174/1567205018666211126113904
Bryant AG, Manhard MK, Salat DH, Rosen BR, Hyman BT, Johnson KA, Huang S, Bennett RE, Yen YF. Heterogeneity of Tau Deposition and Microvascular Involvement in MCI and AD. Curr Alzheimer Res. 2021 Nov 25; doi: 10.2174/1567205018666211126113904. Epub 2021 Nov 25. PMID: 34825871.
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Genome-wide association study and functional validation implicates JADE1 in tauopathy.

Acta neuropathologica

Farrell K, Kim S, Han N, Iida MA, Gonzalez EM, Otero-Garcia M, Walker JM, Richardson TE, Renton AE, Andrews SJ, Fulton-Howard B, Humphrey J, Vialle RA, Bowles KR, de Paiva Lopes K, Whitney K, Dangoor DK, Walsh H, Marcora E, Hefti MM, Casella A, Sissoko CT, Kapoor M, Novikova G, Udine E, Wong G, Tang W, Bhangale T, Hunkapiller J, Ayalon G, Graham RR, Cherry JD, Cortes EP, Borukov VY, McKee AC, Stein TD, Vonsattel JP, Teich AF, Gearing M, Glass J, Troncoso JC, Frosch MP, Hyman BT, Dickson DW, Murray ME, Attems J, Flanagan ME, Mao Q, Mesulam MM, Weintraub S, Woltjer RL, Pham T, Kofler J, Schneider JA, Yu L, Purohit DP, Haroutunian V, Hof PR, Gandy S, Sano M, Beach TG, Poon W, Kawas CH, Corrada MM, Rissman RA, Metcalf J, Shuldberg S, Salehi B, Nelson PT, Trojanowski JQ, Lee EB, Wolk DA, McMillan CT, Keene CD, Latimer CS, Montine TJ, Kovacs GG, Lutz MI, Fischer P, Perrin RJ, Cairns NJ, Franklin EE, Cohen HT, Raj T, Cobos I, Frost B, Goate A, White Iii CL, Crary JF.
PMID: 34719765
Acta Neuropathol. 2022 Jan;143(1):33-53. doi: 10.1007/s00401-021-02379-z. Epub 2021 Nov 01.

Primary age-related tauopathy (PART) is a neurodegenerative pathology with features distinct from but also overlapping with Alzheimer disease (AD). While both exhibit Alzheimer-type temporal lobe neurofibrillary degeneration alongside amnestic cognitive impairment, PART develops independently of amyloid-β (Aβ) plaques. The...

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Farrell K, Kim S, Han N, et al. Genome-wide association study and functional validation implicates JADE1 in tauopathy. Acta Neuropathol. 2021;143(1):33-53doi: 10.1007/s00401-021-02379-z.
Farrell, K., Kim, S., Han, N., Iida, M. A., Gonzalez, E. M., Otero-Garcia, M., Walker, J. M., Richardson, T. E., Renton, A. E., Andrews, S. J., Fulton-Howard, B., Humphrey, J., Vialle, R. A., Bowles, K. R., de Paiva Lopes, K., Whitney, K., Dangoor, D. K., Walsh, H., Marcora, E., Hefti, M. M., Casella, A., Sissoko, C. T., Kapoor, M., Novikova, G., Udine, E., Wong, G., Tang, W., Bhangale, T., Hunkapiller, J., Ayalon, G., Graham, R. R., Cherry, J. D., Cortes, E. P., Borukov, V. Y., McKee, A. C., Stein, T. D., Vonsattel, J. P., Teich, A. F., Gearing, M., Glass, J., Troncoso, J. C., Frosch, M. P., Hyman, B. T., Dickson, D. W., Murray, M. E., Attems, J., Flanagan, M. E., Mao, Q., Mesulam, M. M., Weintraub, S., Woltjer, R. L., Pham, T., Kofler, J., Schneider, J. A., Yu, L., Purohit, D. P., Haroutunian, V., Hof, P. R., Gandy, S., Sano, M., Beach, T. G., Poon, W., Kawas, C. H., Corrada, M. M., Rissman, R. A., Metcalf, J., Shuldberg, S., Salehi, B., Nelson, P. T., Trojanowski, J. Q., Lee, E. B., Wolk, D. A., McMillan, C. T., Keene, C. D., Latimer, C. S., Montine, T. J., Kovacs, G. G., Lutz, M. I., Fischer, P., Perrin, R. J., Cairns, N. J., Franklin, E. E., Cohen, H. T., Raj, T., Cobos, I., Frost, B., Goate, A., White Iii, C. L., & Crary, J. F. (2022). Genome-wide association study and functional validation implicates JADE1 in tauopathy. Acta neuropathologica, 143(1), 33-53. https://doi.org/10.1007/s00401-021-02379-z
Farrell, Kurt, et al. "Genome-wide association study and functional validation implicates JADE1 in tauopathy." Acta neuropathologica vol. 143,1 (2022): 33-53. doi: https://doi.org/10.1007/s00401-021-02379-z
Farrell K, Kim S, Han N, Iida MA, Gonzalez EM, Otero-Garcia M, Walker JM, Richardson TE, Renton AE, Andrews SJ, Fulton-Howard B, Humphrey J, Vialle RA, Bowles KR, de Paiva Lopes K, Whitney K, Dangoor DK, Walsh H, Marcora E, Hefti MM, Casella A, Sissoko CT, Kapoor M, Novikova G, Udine E, Wong G, Tang W, Bhangale T, Hunkapiller J, Ayalon G, Graham RR, Cherry JD, Cortes EP, Borukov VY, McKee AC, Stein TD, Vonsattel JP, Teich AF, Gearing M, Glass J, Troncoso JC, Frosch MP, Hyman BT, Dickson DW, Murray ME, Attems J, Flanagan ME, Mao Q, Mesulam MM, Weintraub S, Woltjer RL, Pham T, Kofler J, Schneider JA, Yu L, Purohit DP, Haroutunian V, Hof PR, Gandy S, Sano M, Beach TG, Poon W, Kawas CH, Corrada MM, Rissman RA, Metcalf J, Shuldberg S, Salehi B, Nelson PT, Trojanowski JQ, Lee EB, Wolk DA, McMillan CT, Keene CD, Latimer CS, Montine TJ, Kovacs GG, Lutz MI, Fischer P, Perrin RJ, Cairns NJ, Franklin EE, Cohen HT, Raj T, Cobos I, Frost B, Goate A, White Iii CL, Crary JF. Genome-wide association study and functional validation implicates JADE1 in tauopathy. Acta Neuropathol. 2022 Jan;143(1):33-53. doi: 10.1007/s00401-021-02379-z. Epub 2021 Nov 01. PMID: 34719765.
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The Effects of 16 Weeks of Exercise Training on Neutrophil Functions in Breast Cancer Survivors.

Frontiers in immunology

Bartlett DB, Hanson ED, Lee JT, Wagoner CW, Harrell EP, Sullivan SA, Bates LC, Alzer MS, Amatuli DJ, Deal AM, Jensen BC, MacDonald G, Deal MA, Muss HB, Nyrop KA, Battaglini CL.
PMID: 34777343
Front Immunol. 2021 Oct 27;12:733101. doi: 10.3389/fimmu.2021.733101. eCollection 2021.

Following therapy, breast cancer survivors (BCS) have an increased risk of infections because of age and cancer dysregulation of inflammation and neutrophil functions. Neutrophil functions may be improved by exercise training, although limited data exist on exercise and neutrophil...

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Bartlett DB, Hanson ED, Lee JT, et al. The Effects of 16 Weeks of Exercise Training on Neutrophil Functions in Breast Cancer Survivors. Front Immunol. 2021;12:733101doi: 10.3389/fimmu.2021.733101.
Bartlett, D. B., Hanson, E. D., Lee, J. T., Wagoner, C. W., Harrell, E. P., Sullivan, S. A., Bates, L. C., Alzer, M. S., Amatuli, D. J., Deal, A. M., Jensen, B. C., MacDonald, G., Deal, M. A., Muss, H. B., Nyrop, K. A., & Battaglini, C. L. (2021). The Effects of 16 Weeks of Exercise Training on Neutrophil Functions in Breast Cancer Survivors. Frontiers in immunology, 12733101. https://doi.org/10.3389/fimmu.2021.733101
Bartlett, David B, et al. "The Effects of 16 Weeks of Exercise Training on Neutrophil Functions in Breast Cancer Survivors." Frontiers in immunology vol. 12 (2021): 733101. doi: https://doi.org/10.3389/fimmu.2021.733101
Bartlett DB, Hanson ED, Lee JT, Wagoner CW, Harrell EP, Sullivan SA, Bates LC, Alzer MS, Amatuli DJ, Deal AM, Jensen BC, MacDonald G, Deal MA, Muss HB, Nyrop KA, Battaglini CL. The Effects of 16 Weeks of Exercise Training on Neutrophil Functions in Breast Cancer Survivors. Front Immunol. 2021 Oct 27;12:733101. doi: 10.3389/fimmu.2021.733101. eCollection 2021. PMID: 34777343; PMCID: PMC8578958.
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APOE4 derived from astrocytes leads to blood-brain barrier impairment.

Brain : a journal of neurology

Jackson RJ, Meltzer JC, Nguyen H, Commins C, Bennett RE, Hudry E, Hyman BT.
PMID: 34957486
Brain. 2021 Dec 27; doi: 10.1093/brain/awab478. Epub 2021 Dec 27.

Apolipoprotein E (ApoE) is a multifaceted secreted molecule synthesized in the CNS by astrocytes and microglia, and in the periphery largely by the liver. ApoE has been shown to impact the integrity of the blood brain barrier, and, in...

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Jackson RJ, Meltzer JC, Nguyen H, et al. APOE4 derived from astrocytes leads to blood-brain barrier impairment. Brain. 2021;doi: 10.1093/brain/awab478.
Jackson, R. J., Meltzer, J. C., Nguyen, H., Commins, C., Bennett, R. E., Hudry, E., & Hyman, B. T. (2021). APOE4 derived from astrocytes leads to blood-brain barrier impairment. Brain : a journal of neurology, . https://doi.org/10.1093/brain/awab478
Jackson, Rosemary J, et al. "APOE4 derived from astrocytes leads to blood-brain barrier impairment." Brain : a journal of neurology vol. (2021). doi: https://doi.org/10.1093/brain/awab478
Jackson RJ, Meltzer JC, Nguyen H, Commins C, Bennett RE, Hudry E, Hyman BT. APOE4 derived from astrocytes leads to blood-brain barrier impairment. Brain. 2021 Dec 27; doi: 10.1093/brain/awab478. Epub 2021 Dec 27. PMID: 34957486.
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An integrated genomic approach to dissect the genetic landscape regulating the cell-to-cell transfer of α-synuclein.

Cell reports

Kara E, Crimi A, Wiedmer A, Emmenegger M, Manzoni C, Bandres-Ciga S, D'Sa K, Reynolds RH, Botía JA, Losa M, Lysenko V, Carta M, Heinzer D, Avar M, Chincisan A, Blauwendraat C, García-Ruiz S, Pease D, Mottier L, Carrella A, Beck-Schneider D, Magalhães AD, Aemisegger C, Theocharides APA, Fan Z, Marks JD, Hopp SC, Abramov AY, Lewis PA, Ryten M, Hardy J, Hyman BT, Aguzzi A.
PMID: 34107263
Cell Rep. 2021 Jun 08;35(10):109189. doi: 10.1016/j.celrep.2021.109189.

Neuropathological and experimental evidence suggests that the cell-to-cell transfer of α-synuclein has an important role in the pathogenesis of Parkinson's disease (PD). However, the mechanism underlying this phenomenon is not fully understood. We undertook a small interfering RNA (siRNA),...

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Kara E, Crimi A, Wiedmer A, et al. An integrated genomic approach to dissect the genetic landscape regulating the cell-to-cell transfer of α-synuclein. Cell Rep. 2021;35(10):109189doi: 10.1016/j.celrep.2021.109189.
Kara, E., Crimi, A., Wiedmer, A., Emmenegger, M., Manzoni, C., Bandres-Ciga, S., D'Sa, K., Reynolds, R. H., Botía, J. A., Losa, M., Lysenko, V., Carta, M., Heinzer, D., Avar, M., Chincisan, A., Blauwendraat, C., García-Ruiz, S., Pease, D., Mottier, L., Carrella, A., Beck-Schneider, D., Magalhães, A. D., Aemisegger, C., Theocharides, A. P. A., Fan, Z., Marks, J. D., Hopp, S. C., Abramov, A. Y., Lewis, P. A., Ryten, M., Hardy, J., Hyman, B. T., & Aguzzi, A. (2021). An integrated genomic approach to dissect the genetic landscape regulating the cell-to-cell transfer of α-synuclein. Cell reports, 35(10), 109189. https://doi.org/10.1016/j.celrep.2021.109189
Kara, Eleanna, et al. "An integrated genomic approach to dissect the genetic landscape regulating the cell-to-cell transfer of α-synuclein." Cell reports vol. 35,10 (2021): 109189. doi: https://doi.org/10.1016/j.celrep.2021.109189
Kara E, Crimi A, Wiedmer A, Emmenegger M, Manzoni C, Bandres-Ciga S, D'Sa K, Reynolds RH, Botía JA, Losa M, Lysenko V, Carta M, Heinzer D, Avar M, Chincisan A, Blauwendraat C, García-Ruiz S, Pease D, Mottier L, Carrella A, Beck-Schneider D, Magalhães AD, Aemisegger C, Theocharides APA, Fan Z, Marks JD, Hopp SC, Abramov AY, Lewis PA, Ryten M, Hardy J, Hyman BT, Aguzzi A. An integrated genomic approach to dissect the genetic landscape regulating the cell-to-cell transfer of α-synuclein. Cell Rep. 2021 Jun 08;35(10):109189. doi: 10.1016/j.celrep.2021.109189. PMID: 34107263; PMCID: PMC8207177.
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Longitudinal differences in everyday preferences: Comparisons between people with cognitive impairment and their care partners.

International journal of geriatric psychiatry

Wilkins JM, Locascio JJ, Gunther JM, Gomez-Isla T, Hyman BT, Blacker D, Forester BP, Okereke OI.
PMID: 34498322
Int J Geriatr Psychiatry. 2021 Sep 08; doi: 10.1002/gps.5620. Epub 2021 Sep 08.

OBJECTIVES: Persons with progressive cognitive impairment (CI) increasingly rely on surrogate decision-makers for everyday activities. Yet, little is known about changes in everyday preferences over time or about concordance between persons with CI and their care partners regarding longitudinal...

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Wilkins JM, Locascio JJ, Gunther JM, et al. Longitudinal differences in everyday preferences: Comparisons between people with cognitive impairment and their care partners. Int J Geriatr Psychiatry. 2021;doi: 10.1002/gps.5620.
Wilkins, J. M., Locascio, J. J., Gunther, J. M., Gomez-Isla, T., Hyman, B. T., Blacker, D., Forester, B. P., & Okereke, O. I. (2021). Longitudinal differences in everyday preferences: Comparisons between people with cognitive impairment and their care partners. International journal of geriatric psychiatry, . https://doi.org/10.1002/gps.5620
Wilkins, James M, et al. "Longitudinal differences in everyday preferences: Comparisons between people with cognitive impairment and their care partners." International journal of geriatric psychiatry vol. (2021). doi: https://doi.org/10.1002/gps.5620
Wilkins JM, Locascio JJ, Gunther JM, Gomez-Isla T, Hyman BT, Blacker D, Forester BP, Okereke OI. Longitudinal differences in everyday preferences: Comparisons between people with cognitive impairment and their care partners. Int J Geriatr Psychiatry. 2021 Sep 08; doi: 10.1002/gps.5620. Epub 2021 Sep 08. PMID: 34498322.
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Impact of Sterilization Methods on the Seeding Ability of Human Tau Proteopathic Seeds.

Journal of neuropathology and experimental neurology

Fernandes AR, Dujardin S, Maté de Gérando A, Hyman BT, Frosch MP.
PMID: 34498073
J Neuropathol Exp Neurol. 2021 Oct 26;80(10):912-921. doi: 10.1093/jnen/nlab087.

The protein tau, when misfolded in neurodegenerative diseases, has several prion-like properties including being able to spread by cell-to-cell transfer, induce templated seeding, and exist in distinct conformational strains. These properties of transmission may present health hazards when lesion-containing...

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Fernandes AR, Dujardin S, Maté de Gérando A, et al. Impact of Sterilization Methods on the Seeding Ability of Human Tau Proteopathic Seeds. J Neuropathol Exp Neurol. 2021;80(10):912-921doi: 10.1093/jnen/nlab087.
Fernandes, A. R., Dujardin, S., Maté de Gérando, A., Hyman, B. T., & Frosch, M. P. (2021). Impact of Sterilization Methods on the Seeding Ability of Human Tau Proteopathic Seeds. Journal of neuropathology and experimental neurology, 80(10), 912-921. https://doi.org/10.1093/jnen/nlab087
Fernandes, Analiese R, et al. "Impact of Sterilization Methods on the Seeding Ability of Human Tau Proteopathic Seeds." Journal of neuropathology and experimental neurology vol. 80,10 (2021): 912-921. doi: https://doi.org/10.1093/jnen/nlab087
Fernandes AR, Dujardin S, Maté de Gérando A, Hyman BT, Frosch MP. Impact of Sterilization Methods on the Seeding Ability of Human Tau Proteopathic Seeds. J Neuropathol Exp Neurol. 2021 Oct 26;80(10):912-921. doi: 10.1093/jnen/nlab087. PMID: 34498073.
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Correction notices in psychology: impactful or inconsequential?.

Royal Society open science

Heyman T, Maerten AS.
PMID: 33204456
R Soc Open Sci. 2020 Oct 07;7(10):200834. doi: 10.1098/rsos.200834. eCollection 2020 Oct.

Science is self-correcting, or so the adage goes, but to what extent is that indeed the case? Answering this question requires careful consideration of the various approaches to achieve the collective goal of self-correction. One of the most straightforward...

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Heyman T, Maerten AS. Correction notices in psychology: impactful or inconsequential?. R Soc Open Sci. 2020;7(10):200834doi: 10.1098/rsos.200834.
Heyman, T., & Maerten, A. S. (2020). Correction notices in psychology: impactful or inconsequential?. Royal Society open science, 7(10), 200834. https://doi.org/10.1098/rsos.200834
Heyman, Tom, and Maerten, Anne-Sofie. "Correction notices in psychology: impactful or inconsequential?." Royal Society open science vol. 7,10 (2020): 200834. doi: https://doi.org/10.1098/rsos.200834
Heyman T, Maerten AS. Correction notices in psychology: impactful or inconsequential?. R Soc Open Sci. 2020 Oct 07;7(10):200834. doi: 10.1098/rsos.200834. eCollection 2020 Oct. PMID: 33204456; PMCID: PMC7657932.
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The benefits of adversarial collaboration for commentaries.

Nature human behaviour

Heyman T, Moors P, Rabagliati H.
PMID: 33106628
Nat Hum Behav. 2020 Dec;4(12):1217. doi: 10.1038/s41562-020-00978-6.

No abstract available.

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Heyman T, Moors P, Rabagliati H. The benefits of adversarial collaboration for commentaries. Nat Hum Behav. 2020;4(12):1217doi: 10.1038/s41562-020-00978-6.
Heyman, T., Moors, P., & Rabagliati, H. (2020). The benefits of adversarial collaboration for commentaries. Nature human behaviour, 4(12), 1217. https://doi.org/10.1038/s41562-020-00978-6
Heyman, Tom, et al. "The benefits of adversarial collaboration for commentaries." Nature human behaviour vol. 4,12 (2020): 1217. doi: https://doi.org/10.1038/s41562-020-00978-6
Heyman T, Moors P, Rabagliati H. The benefits of adversarial collaboration for commentaries. Nat Hum Behav. 2020 Dec;4(12):1217. doi: 10.1038/s41562-020-00978-6. PMID: 33106628.
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Online monitoring of the respiratory quotient reveals metabolic phases during microaerobic 2,3-butanediol production with .

Engineering in life sciences

Heyman B, Tulke H, Putri SP, Fukusaki E, Büchs J.
PMID: 32874177
Eng Life Sci. 2019 Nov 28;20(3):133-144. doi: 10.1002/elsc.201900121. eCollection 2020 Mar.

Microaerobic cultivation conditions are often beneficial for the biotechnological production of reduced metabolites like 2,3-butanediol. However, due to oxygen limitation, process monitoring based on oxygen transfer rate, or dissolved oxygen measurement provides only limited information. In this study, online...

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Heyman B, Tulke H, Putri SP, et al. Online monitoring of the respiratory quotient reveals metabolic phases during microaerobic 2,3-butanediol production with . Eng Life Sci. 2019;20(3):133-144doi: 10.1002/elsc.201900121.
Heyman, B., Tulke, H., Putri, S. P., Fukusaki, E., & Büchs, J. (2020). Online monitoring of the respiratory quotient reveals metabolic phases during microaerobic 2,3-butanediol production with . Engineering in life sciences, 20(3), 133-144. https://doi.org/10.1002/elsc.201900121
Heyman, Benedikt, et al. "Online monitoring of the respiratory quotient reveals metabolic phases during microaerobic 2,3-butanediol production with ." Engineering in life sciences vol. 20,3 (2020): 133-144. doi: https://doi.org/10.1002/elsc.201900121
Heyman B, Tulke H, Putri SP, Fukusaki E, Büchs J. Online monitoring of the respiratory quotient reveals metabolic phases during microaerobic 2,3-butanediol production with . Eng Life Sci. 2019 Nov 28;20(3):133-144. doi: 10.1002/elsc.201900121. eCollection 2020 Mar. PMID: 32874177; PMCID: PMC7447875.
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Analysis of α-synuclein species enriched from cerebral cortex of humans with sporadic dementia with Lewy bodies.

Brain communications

Sanderson JB, De S, Jiang H, Rovere M, Jin M, Zaccagnini L, Hays Watson A, De Boni L, Lagomarsino VN, Young-Pearse TL, Liu X, Pochapsky TC, Hyman BT, Dickson DW, Klenerman D, Selkoe DJ, Bartels T.
PMID: 32280944
Brain Commun. 2020;2(1):fcaa010. doi: 10.1093/braincomms/fcaa010. Epub 2020 Feb 11.

Since researchers identified α-synuclein as the principal component of Lewy bodies and Lewy neurites, studies have suggested that it plays a causative role in the pathogenesis of dementia with Lewy bodies and other 'synucleinopathies'. While α-synuclein dyshomeostasis likely contributes...

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Sanderson JB, De S, Jiang H, et al. Analysis of α-synuclein species enriched from cerebral cortex of humans with sporadic dementia with Lewy bodies. Brain Commun. 2020;2(1):fcaa010doi: 10.1093/braincomms/fcaa010.
Sanderson, J. B., De, S., Jiang, H., Rovere, M., Jin, M., Zaccagnini, L., Hays Watson, A., De Boni, L., Lagomarsino, V. N., Young-Pearse, T. L., Liu, X., Pochapsky, T. C., Hyman, B. T., Dickson, D. W., Klenerman, D., Selkoe, D. J., & Bartels, T. (2020). Analysis of α-synuclein species enriched from cerebral cortex of humans with sporadic dementia with Lewy bodies. Brain communications, 2(1), fcaa010. https://doi.org/10.1093/braincomms/fcaa010
Sanderson, John B, et al. "Analysis of α-synuclein species enriched from cerebral cortex of humans with sporadic dementia with Lewy bodies." Brain communications vol. 2,1 (2020): fcaa010. doi: https://doi.org/10.1093/braincomms/fcaa010
Sanderson JB, De S, Jiang H, Rovere M, Jin M, Zaccagnini L, Hays Watson A, De Boni L, Lagomarsino VN, Young-Pearse TL, Liu X, Pochapsky TC, Hyman BT, Dickson DW, Klenerman D, Selkoe DJ, Bartels T. Analysis of α-synuclein species enriched from cerebral cortex of humans with sporadic dementia with Lewy bodies. Brain Commun. 2020;2(1):fcaa010. doi: 10.1093/braincomms/fcaa010. Epub 2020 Feb 11. PMID: 32280944; PMCID: PMC7130446.
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Effects of Breast Cancer Adjuvant Chemotherapy Regimens on Expression of the Aging Biomarker, .

JNCI cancer spectrum

Shachar SS, Deal AM, Reeder-Hayes KE, Nyrop KA, Mitin N, Anders CK, Carey LA, Dees EC, Jolly TA, Kimmick GG, Karuturi MS, Reinbolt RE, Speca JC, Muss HB.
PMID: 33409457
JNCI Cancer Spectr. 2020 Dec 18;4(6):pkaa082. doi: 10.1093/jncics/pkaa082. eCollection 2020 Dec.

BACKGROUND: Although chemotherapy saves lives, increasing evidence shows that chemotherapy accelerates aging. We previously demonstrated that mRNA expression of METHODS: We conducted a study of stage I-III breast cancer patients receiving adjuvant or neoadjuvant chemotherapy. RESULTS: In 146 women,...

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Shachar SS, Deal AM, Reeder-Hayes KE, et al. Effects of Breast Cancer Adjuvant Chemotherapy Regimens on Expression of the Aging Biomarker, . JNCI Cancer Spectr. 2020;4(6):pkaa082doi: 10.1093/jncics/pkaa082.
Shachar, S. S., Deal, A. M., Reeder-Hayes, K. E., Nyrop, K. A., Mitin, N., Anders, C. K., Carey, L. A., Dees, E. C., Jolly, T. A., Kimmick, G. G., Karuturi, M. S., Reinbolt, R. E., Speca, J. C., & Muss, H. B. (2020). Effects of Breast Cancer Adjuvant Chemotherapy Regimens on Expression of the Aging Biomarker, . JNCI cancer spectrum, 4(6), pkaa082. https://doi.org/10.1093/jncics/pkaa082
Shachar, Shlomit S, et al. "Effects of Breast Cancer Adjuvant Chemotherapy Regimens on Expression of the Aging Biomarker, ." JNCI cancer spectrum vol. 4,6 (2020): pkaa082. doi: https://doi.org/10.1093/jncics/pkaa082
Shachar SS, Deal AM, Reeder-Hayes KE, Nyrop KA, Mitin N, Anders CK, Carey LA, Dees EC, Jolly TA, Kimmick GG, Karuturi MS, Reinbolt RE, Speca JC, Muss HB. Effects of Breast Cancer Adjuvant Chemotherapy Regimens on Expression of the Aging Biomarker, . JNCI Cancer Spectr. 2020 Dec 18;4(6):pkaa082. doi: 10.1093/jncics/pkaa082. eCollection 2020 Dec. PMID: 33409457; PMCID: PMC7771421.
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