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Showing 145 to 155 of 155 entries
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Volunteer patients and small groups contribute to abdominal examination's success.

Advances in medical education and practice

Shields HM, Fernandez-Becker NQ, Flier SN, Vaughn BP, Tukey MH, Pelletier SR, Horst DA.
PMID: 29138611
Adv Med Educ Pract. 2017 Nov 01;8:721-729. doi: 10.2147/AMEP.S146500. eCollection 2017.

BACKGROUND: Prior to 2007, we taught the abdominal examination in a hospital based group to 40 students, at one hospital. We used volunteer patients, small groups, repetition, and required faculty development sessions. In 2007, our medical school changed its...

Potential of mean force for two nanocrystals: Core geometry and size, hydrocarbon unsaturation, and universality with respect to the force field.

The Journal of chemical physics

Waltmann C, Horst N, Travesset A.
PMID: 30037257
J Chem Phys. 2018 Jul 21;149(3):034109. doi: 10.1063/1.5039495.

We present a detailed analysis of the interaction between two nanocrystals capped with ligands consisting of hydrocarbon chains by united atom molecular dynamics simulations. We analyze large cores (up to 10 nm in diameter) and ligands with unsaturated carbon...

Newborn Pulse Oximetry for Infants Born Out-of-Hospital.

Pediatrics

Williams KB, Horst M, Hollinger EA, Freedman J, Demczko MM, Chowdhury D.
PMID: 34531289
Pediatrics. 2021 Oct;148(4). doi: 10.1542/peds.2020-048785. Epub 2021 Sep 16.

BACKGROUND AND OBJECTIVES: Conventional timing of newborn pulse oximetry screening is not ideal for infants born out-of-hospital. We implemented a newborn pulse oximetry screen to align with typical midwifery care and measure its efficacy at detecting critical congenital heart...

Physiological Correlates of Processing Health-Related Information: An Idea for the Adoption of a Foreign Field.

Nursing reports (Pavia, Italy)

Geukes C, Müller HM.
PMID: 34968322
Nurs Rep. 2021 Mar 17;11(1):175-186. doi: 10.3390/nursrep11010017.

Measuring health may refer to the measurement of general health status through measures of physical function, pain, social health, psychological aspects, and specific disease. Almost no evidence is available on the possible interaction of physiological measures and correlating emotional-affective...

Polymorphism .

The British journal of nutrition

Holzbach LC, Silveira AGZ, Franco LP, Horst MA, Cominetti C.
PMID: 34725012
Br J Nutr. 2021 Nov 02;1-9. doi: 10.1017/S0007114521004396. Epub 2021 Nov 02.

Evidence shows that genetic polymorphisms in perilipin 1 gene (PLIN1) are associated with excessive accumulation of body fat and disturbances in cardiometabolic markers. Therefore, the aim of this study was to verify whether the SNP PLIN1 11482 G>A (rs894160)...

Neonatal Fever in the COVID-19 Pandemic: Odds of a Serious Bacterial Infection.

Pediatric emergency care

Mittal S, Muthusami S, Marlowe L, Knerr S, Prasto J, Cooke TA, Bochenski J, Horst MA.
PMID: 34986582
Pediatr Emerg Care. 2022 Jan 01;38(1):43-47. doi: 10.1097/PEC.0000000000002601.

OBJECTIVES: A sepsis workup is recommended in young infants 56 days or younger with fever to rule out a serious bacterial infection (SBI). Given the reduction in non-severe acute respiratory syndrome - coronavirus 2 viral infections observed in multiple...

Fibroblast Activation Protein Targeted Photodynamic Therapy Selectively Kills Activated Skin Fibroblasts from Systemic Sclerosis Patients and Prevents Tissue Contraction.

International journal of molecular sciences

Dorst DN, van Caam APM, Vitters EL, Walgreen B, Helsen MMA, Klein C, Gudi S, Wubs T, Kumari J, Vonk MC, van der Kraan PM, Koenders MI.
PMID: 34884484
Int J Mol Sci. 2021 Nov 24;22(23). doi: 10.3390/ijms222312681.

Systemic sclerosis (SSc) is a rare, severe, auto-immune disease characterized by inflammation, vasculopathy and fibrosis. Activated (myo)fibroblasts are crucial drivers of this fibrosis. By exploiting their expression of fibroblast activation protein (FAP) to perform targeted photodynamic therapy (tPDT), we...

Photodynamic Therapy Targeting Macrophages Using IRDye700DX-Liposomes Decreases Experimental Arthritis Development.

Pharmaceutics

Dorst DN, Boss M, Rijpkema M, Walgreen B, Helsen MMA, Bos DL, van Bloois L, Storm G, Brom M, Laverman P, van der Kraan PM, Buitinga M, Koenders MI, Gotthardt M.
PMID: 34834283
Pharmaceutics. 2021 Nov 05;13(11). doi: 10.3390/pharmaceutics13111868.

Macrophages play a crucial role in the initiation and progression of rheumatoid arthritis (RA). Liposomes can be used to deliver therapeutics to macrophages by exploiting their phagocytic ability. However, since macrophages serve as the immune system's first responders, it...

Comparing Smoking Cessation Interventions among Underserved Patients Referred for Lung Cancer Screening: A Pragmatic Trial Protocol.

Annals of the American Thoracic Society

Kohn R, Vachani A, Small D, Stephens-Shields AJ, Sheu D, Madden VL, Bayes BA, Chowdhury M, Friday S, Kim J, Gould MK, Ismail MH, Creekmur B, Facktor MA, Collins C, Blessing KK, Neslund-Dudas CM, Simoff MJ, Alleman ER, Epstein LH, Horst MA, Scott ME, Volpp KG, Halpern SD, Hart JL.
PMID: 34384042
Ann Am Thorac Soc. 2021 Aug 12; doi: 10.1513/AnnalsATS.202104-499SD. Epub 2021 Aug 12.

Smoking burdens are greatest among underserved patients. Lung cancer screening (LCS) reduces mortality among individuals at risk for smoking-associated lung cancer. Although LCS programs must offer smoking cessation support, the interventions that best promote cessation among underserved patients in...

Safety and Efficacy of Vedolizumab Versus Tumor Necrosis Factor α Antagonists in an Elderly IBD Population: A Single Institution Retrospective Experience.

Digestive diseases and sciences

Pabla BS, Alex Wiles C, Slaughter JC, Scoville EA, Dalal RL, Beaulieu DB, Schwartz DA, Horst SN.
PMID: 34268660
Dig Dis Sci. 2021 Jul 15; doi: 10.1007/s10620-021-07129-5. Epub 2021 Jul 15.

BACKGROUND: Vedolizumab is a monoclonal antibody used to treat inflammatory bowel disease (IBD). There is little known about the safety and comparative efficacy of this agent in the elderly population.AIMS: Here, we present data on the safety and comparative...

Targeting of fibroblast activation protein in rheumatoid arthritis patients: imaging and ex vivo photodynamic therapy.

Rheumatology (Oxford, England)

Dorst DN, Rijpkema M, Buitinga M, Walgreen B, Helsen MMA, Brennan E, Klein C, Laverman P, Ramming A, Schmidkonz C, Kuwert T, Schett G, van der Kraan PM, Gotthardt M, Koenders MI.
PMID: 34450633
Rheumatology (Oxford). 2021 Aug 27; doi: 10.1093/rheumatology/keab664. Epub 2021 Aug 27.

OBJECTIVE: Activated synovial fibroblasts are key effector cells in rheumatoid arthritis (RA). Selectively depleting these based upon their expression of fibroblast activation protein (FAP) is an attractive therapeutic approach. Here we introduce FAP imaging of inflamed joints using [68Ga]Ga-FAPI-04...

Showing 145 to 155 of 155 entries