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Showing 1381 to 1388 of 1388 entries
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Cohesin mediates DNA loop extrusion by a "swing and clamp" mechanism.

Cell

Bauer BW, Davidson IF, Canena D, Wutz G, Tang W, Litos G, Horn S, Hinterdorfer P, Peters JM.
PMID: 34624221
Cell. 2021 Oct 14;184(21):5448-5464.e22. doi: 10.1016/j.cell.2021.09.016. Epub 2021 Oct 07.

Structural maintenance of chromosomes (SMC) complexes organize genome topology in all kingdoms of life and have been proposed to perform this function by DNA loop extrusion. How this process works is unknown. Here, we have analyzed how loop extrusion...

Can tibio-femoral kinematic and kinetic parameters reveal poor functionality and underlying deficits after total knee replacement? A systematic review.

The Knee

Rao L, Taylor WR, Horn N, List R, Preiss S, Schütz P.
PMID: 34883331
Knee. 2021 Dec 06;34:62-75. doi: 10.1016/j.knee.2021.11.002. Epub 2021 Dec 06.

BACKGROUND: Extensive efforts have been made to understand joint kinematics and kinetics in total knee arthroplasty (TKA) in subjects with satisfactory outcomes during daily functional activities and clinical tests, but it remains unclear whether such movement characteristics hold the...

Latrophilin-1 drives neuron morphogenesis and shapes chemo- and mechanosensation-dependent behavior in C. elegans via a trans function.

Biochemical and biophysical research communications

Matúš D, Post WB, Horn S, Schöneberg T, Prömel S.
PMID: 34922196
Biochem Biophys Res Commun. 2022 Jan 22;589:152-158. doi: 10.1016/j.bbrc.2021.12.006. Epub 2021 Dec 05.

Latrophilins are highly conserved Adhesion GPCRs playing essential roles in the mammalian nervous system and are associated with severe neurological disorders. Recently, it has been shown that murine Latrophilins mediate classical G-protein signals to drive synaptogenesis. However, there is...

Ag nanoparticles outperform Au nanoparticles for the use as label in electrochemical point-of-care sensors.

Analytical and bioanalytical chemistry

Beck F, Horn C, Baeumner AJ.
PMID: 33787969
Anal Bioanal Chem. 2021 Mar 31; doi: 10.1007/s00216-021-03288-6. Epub 2021 Mar 31.

Electrochemical immunosensors enable rapid analyte quantification in small sample volumes, and have been demonstrated to provide high sensitivity and selectivity, simple miniaturization, and easy sensor production strategies. As a point-of-care (POC) format, user-friendliness is equally important and most often...

Technology of deep brain stimulation: current status and future directions.

Nature reviews. Neurology

Krauss JK, Lipsman N, Aziz T, Boutet A, Brown P, Chang JW, Davidson B, Grill WM, Hariz MI, Horn A, Schulder M, Mammis A, Tass PA, Volkmann J, Lozano AM.
PMID: 33244188
Nat Rev Neurol. 2021 Feb;17(2):75-87. doi: 10.1038/s41582-020-00426-z. Epub 2020 Nov 26.

Deep brain stimulation (DBS) is a neurosurgical procedure that allows targeted circuit-based neuromodulation. DBS is a standard of care in Parkinson disease, essential tremor and dystonia, and is also under active investigation for other conditions linked to pathological circuitry,...

A prospective multicenter study of the magnifying endoscopic evaluation of the invasion depth of superficial esophageal cancers.

Surgical endoscopy

Gotoda T, Hori K, Nakagawa M, Kobayashi S, Toyokawa T, Ishiyama S, Imagawa A, Abe M, Kono Y, Kanzaki H, Iwamuro M, Kawano S, Kawahara Y, Okada H.
PMID: 34322721
Surg Endosc. 2021 Jul 28; doi: 10.1007/s00464-021-08666-w. Epub 2021 Jul 28.

BACKGROUND: Treatment strategies for superficial esophageal squamous cell carcinoma (SESCC) are determined mainly on the basis of the invasion depth. The Japan Esophageal Society (JES) developed a simplified magnifying endoscopic classification for estimating the invasion depth of SESCC. We...

Gender and generational influences on the pediatric workforce and practice.

Spector ND, Cull W, Daniels SR, Gilhooly J, Hall J, Horn I, Marshall SG, Schumacher DJ, Sectish TC, Stanton BF.
UIID-AD: 2890
2014;133:1112-21. doi: 10.1542/peds.2013-3016.

In response to demographic and other trends that may affect the future of the field of pediatrics, the Federation of Pediatric Organizations formed 4 working groups to participate in a year's worth of research and discussion preliminary to a...

Bringing computational thinking into high school mathematics and science classrooms.

Orton K, Weintrop D, Beheshti E, Horn M, Jona K, Wilensky U.
UIID-AD: 3726
2016;705-712.

Computation is reshaping modern science and mathematics practices, but relatively few students have access to, or take, courses that adequately prepare them for the increasingly technological nature of these fields. Further, students who do study computational topics tend to...

Showing 1381 to 1388 of 1388 entries