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Showing 193 to 197 of 197 entries
Sorted by: Best Match Show Resources per page
Tracing TET1 expression in prostate cancer: discovery of malignant cells with a distinct oncogenic signature.

Clinical epigenetics

Schagdarsurengin U, Luo C, Slanina H, Sheridan D, Füssel S, Böğürcü-Seidel N, Gattenloehner S, Baretton GB, Hofbauer LC, Wagenlehner F, Dansranjav T.
PMID: 34844636
Clin Epigenetics. 2021 Nov 29;13(1):211. doi: 10.1186/s13148-021-01201-7.

BACKGROUND: Ten-eleven translocation methylcytosine dioxygenase 1 (TET1) is involved in DNA demethylation and transcriptional regulation, plays a key role in the maintenance of stem cell pluripotency, and is dysregulated in malignant cells. The identification of cancer stem cells (CSCs)...

TOUCH.

Journal of clinical medicine

Froschauer SM, Holzbauer M, Mihalic JA, Kwasny O.
PMID: 34575201
J Clin Med. 2021 Sep 10;10(18). doi: 10.3390/jcm10184090.

The dual mobility concept currently represents the newest generation of thumb carpometacarpal prostheses. The aim of this study was to evaluate the short-term outcomes of TOUCH

Comparison of SARS-CoV-2 Antibody Response 4 Weeks After Homologous vs Heterologous Third Vaccine Dose in Kidney Transplant Recipients: A Randomized Clinical Trial.

JAMA internal medicine

Reindl-Schwaighofer R, Heinzel A, Mayrdorfer M, Jabbour R, Hofbauer TM, Merrelaar A, Eder M, Regele F, Doberer K, Spechtl P, Aschauer C, Koblischke M, Paschen C, Eskandary F, Hu K, Öhler B, Bhandal A, Kleibenböck S, Jagoditsch RI, Reiskopf B, Heger F, Bond G, Böhmig GA, Strassl R, Weseslindtner L, Indra A, Aberle JH, Binder M, Oberbauer R.
PMID: 34928302
JAMA Intern Med. 2021 Dec 20; doi: 10.1001/jamainternmed.2021.7372. Epub 2021 Dec 20.

IMPORTANCE: Fewer than 50% of kidney transplant recipients (KTRs) develop antibodies against the SARS-CoV-2 spike protein after 2 doses of an mRNA vaccine. Preliminary data suggest that a heterologous vaccination, combining mRNA and viral vector vaccines, may increase immunogenicity.OBJECTIVE:...

Luspatercept restores SDF-1-mediated hematopoietic support by MDS-derived mesenchymal stromal cells.

Leukemia

Wobus M, Mies A, Asokan N, Oelschlägel U, Möbus K, Winter S, Cross M, Weidner H, Rauner M, Hofbauer LC, Bornhäuser M, Platzbecker U.
PMID: 34002031
Leukemia. 2021 Oct;35(10):2936-2947. doi: 10.1038/s41375-021-01275-5. Epub 2021 May 17.

The bone marrow microenvironment (BMME) plays a key role in the pathophysiology of myelodysplastic syndromes (MDS), clonal blood disorders affecting the differentiation, and maturation of hematopoietic stem and progenitor cells (HSPCs). In lower-risk MDS patients, ineffective late-stage erythropoiesis can...

Cardioids reveal self-organizing principles of human cardiogenesis.

Cell

Hofbauer P, Jahnel SM, Papai N, Giesshammer M, Deyett A, Schmidt C, Penc M, Tavernini K, Grdseloff N, Meledeth C, Ginistrelli LC, Ctortecka C, Šalic Š, Novatchkova M, Mendjan S.
PMID: 34019794
Cell. 2021 Jun 10;184(12):3299-3317.e22. doi: 10.1016/j.cell.2021.04.034. Epub 2021 May 20.

Organoids capable of forming tissue-like structures have transformed our ability to model human development and disease. With the notable exception of the human heart, lineage-specific self-organizing organoids have been reported for all major organs. Here, we established self-organizing cardioids...

Showing 193 to 197 of 197 entries