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Showing 37 to 48 of 247 entries
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PCSK9 Activity Is Potentiated Through HDL Binding.

Circulation research

Burnap SA, Sattler K, Pechlaner R, Duregotti E, Lu R, Theofilatos K, Takov K, Heusch G, Tsimikas S, Fernández-Hernando C, Berry SE, Hall WL, Notdurfter M, Rungger G, Paulweber B, Willeit J, Kiechl S, Levkau B, Mayr M.
PMID: 34601896
Circ Res. 2021 Nov 12;129(11):1039-1053. doi: 10.1161/CIRCRESAHA.121.319272. Epub 2021 Oct 04.

[Figure: see text].

Prenatal histological, cellular, and molecular anomalies in trisomy 21 lung.

The Journal of pathology

Danopoulos S, Bhattacharya S, Deutsch G, Nih LR, Slaunwhite C, Mariani TJ, Al Alam D.
PMID: 34050678
J Pathol. 2021 Sep;255(1):41-51. doi: 10.1002/path.5735. Epub 2021 Jun 23.

Down syndrome (DS), also known as trisomy 21 (T21), is the most common human chromosomal anomaly. Although DS can affect many organ systems, lung and heart disease are the leading causes of death. An abundance of existing data suggests...

Mitochondrial Telomerase Reverse Transcriptase Protects From Myocardial Ischemia/Reperfusion Injury by Improving Complex I Composition and Function.

Circulation

Ale-Agha N, Jakobs P, Goy C, Zurek M, Rosen J, Dyballa-Rukes N, Metzger S, Greulich J, von Ameln F, Eckermann O, Unfried K, Brack F, Grandoch M, Thielmann M, Kamler M, Gedik N, Kleinbongard P, Heinen A, Heusch G, Gödecke A, Altschmied J, Haendeler J.
PMID: 34672678
Circulation. 2021 Dec 07;144(23):1876-1890. doi: 10.1161/CIRCULATIONAHA.120.051923. Epub 2021 Oct 21.

BACKGROUND: The catalytic subunit of telomerase, telomerase reverse transcriptase (TERT), has protective functions in the cardiovascular system. TERT is not only present in the nucleus but also in mitochondria. However, it is unclear whether nuclear or mitochondrial TERT is...

Evaluation of a programming algorithm for deep brain stimulation in dystonia used in a double-blind, sham-controlled multicenter study.

Neurological research and practice

Steigerwald F, Kirsch AD, Kühn AA, Kupsch A, Mueller J, Eisner W, Deuschl G, Falk D, Schnitzler A, Skogseid IM, Vollmer-Haase J, Ip CW, Tronnier V, Vesper J, Naumann M, Volkmann J.
PMID: 33324891
Neurol Res Pract. 2019 Sep 24;1:25. doi: 10.1186/s42466-019-0032-2. eCollection 2019.

BACKGROUND: Programming deep brain stimulation in dystonia is difficult because of the delayed benefits and absence of evidence-based guidelines. Therefore, we evaluated the efficacy of a programming algorithm applied in a double-blind, sham-controlled multicenter study of pallidal deep brain...

Moderate Frequency Resistance and Balance Training Do Not Improve Freezing of Gait in Parkinson's Disease: A Pilot Study.

Frontiers in neurology

Schlenstedt C, Paschen S, Seuthe J, Raethjen J, Berg D, Maetzler W, Deuschl G.
PMID: 30619044
Front Neurol. 2018 Dec 10;9:1084. doi: 10.3389/fneur.2018.01084. eCollection 2018.

No abstract available.

Tremor with congenital mirror movements: evidence of involvement of the primary motor cortex in tremor.

European journal of neurology

Isayama R, Chen R, Lang AE, Deuschl G, Fasano A.
PMID: 31034740
Eur J Neurol. 2019 Jun;26(6):e66-e67. doi: 10.1111/ene.13901.

No abstract available.

Providing a phylogenetic framework for trait-based analyses in brown algae: phylogenomic tree inferred from 32 nuclear protein-coding sequences.

Molecular phylogenetics and evolution

Akita S, Vieira C, Hanyuda T, Rousseau F, Cruaud C, Couloux A, Heesch S, Mark Cock J, Kawai H.
PMID: 35031471
Mol Phylogenet Evol. 2022 Jan 11;107408. doi: 10.1016/j.ympev.2022.107408. Epub 2022 Jan 11.

In the study of the evolution of biological complexity, a reliable phylogenetic framework is needed. Many attempts have been made to resolve phylogenetic relationships between higher groups (i.e., interordinal) of brown algae (Phaeophyceae) based on molecular evidence, but most...

Uptake and effectiveness of a self-guided mobile app platform for college student mental health.

Internet interventions

Lattie EG, Cohen KA, Hersch E, Williams KDA, Kruzan KP, MacIver C, Hermes J, Maddi K, Kwasny M, Mohr DC.
PMID: 35036331
Internet Interv. 2021 Dec 24;27:100493. doi: 10.1016/j.invent.2021.100493. eCollection 2022 Mar.

BACKGROUND: College students endorse high rates of mental health problems. While many colleges offer on-campus services, many students who could benefit from mental health services do not receive care. Indeed, nearly half of students who screen positive for depression,...

Frequency-specific network activity predicts bradykinesia severity in Parkinson's disease.

NeuroImage. Clinical

Muthuraman M, Palotai M, Jávor-Duray B, Kelemen A, Koirala N, Halász L, Erőss L, Fekete G, Bognár L, Deuschl G, Tamás G.
PMID: 34662779
Neuroimage Clin. 2021;32:102857. doi: 10.1016/j.nicl.2021.102857. Epub 2021 Oct 13.

OBJECTIVE: Bradykinesia has been associated with beta and gamma band interactions in the basal ganglia-thalamo-cortical circuit in Parkinson's disease. In this present cross-sectional study, we aimed to search for neural networks with electroencephalography whose frequency-specific actions may predict bradykinesia.METHODS:...

Dr. John Ross Jr.

European heart journal

Condorelli G, Heusch G.
PMID: 33215654
Eur Heart J. 2019 Jul 01;40(25):2004-2005. doi: 10.1093/eurheartj/ehz420.

No abstract available.

The Effect of Medication and Deep Brain Stimulation on Posture in Parkinson's Disease.

Frontiers in neurology

Schlenstedt C, Gavriliuc O, Boße K, Wolke R, Granert O, Deuschl G, Margraf NG.
PMID: 31849818
Front Neurol. 2019 Dec 03;10:1254. doi: 10.3389/fneur.2019.01254. eCollection 2019.

No abstract available.

Dietary Piperine is Transferred into the Milk of Nursing Mothers.

Molecular nutrition & food research

N Diaye K, Debong M, Behr J, Dirndorfer S, Duggan T, Beusch A, Schlagbauer V, Dawid C, Loos HM, Buettner A, Lang R, Hofmann T.
PMID: 34633734
Mol Nutr Food Res. 2021 Dec;65(23):e2100508. doi: 10.1002/mnfr.202100508. Epub 2021 Oct 20.

INTRODUCTION: The diet of breastfeeding mothers could bring nurslings into contact with flavor compounds putatively contributing to early sensory programming of the infant. The study investigates whether tastants from a customary curry dish consumed by mothers are detectable in...

Showing 37 to 48 of 247 entries