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Showing 37 to 48 of 192 entries
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Beyond Colonoscopy: Exploring New Cell Surface Biomarkers for Detection of Early, Heterogenous Colorectal Lesions.

Frontiers in oncology

Ramezani S, Parkhideh A, Bhattacharya PK, Farach-Carson MC, Harrington DA.
PMID: 34290978
Front Oncol. 2021 Jul 05;11:657701. doi: 10.3389/fonc.2021.657701. eCollection 2021.

Colorectal cancer (CRC) is the third leading cause of cancer-related deaths among both men and women in the United States. Early detection and surgical removal of high-risk lesions in the colon can prevent disease from developing and spreading. Despite...

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Ramezani S, Parkhideh A, Bhattacharya PK, et al. Beyond Colonoscopy: Exploring New Cell Surface Biomarkers for Detection of Early, Heterogenous Colorectal Lesions. Front Oncol. 2021;11:657701doi: 10.3389/fonc.2021.657701.
Ramezani, S., Parkhideh, A., Bhattacharya, P. K., Farach-Carson, M. C., & Harrington, D. A. (2021). Beyond Colonoscopy: Exploring New Cell Surface Biomarkers for Detection of Early, Heterogenous Colorectal Lesions. Frontiers in oncology, 11657701. https://doi.org/10.3389/fonc.2021.657701
Ramezani, Saleh, et al. "Beyond Colonoscopy: Exploring New Cell Surface Biomarkers for Detection of Early, Heterogenous Colorectal Lesions." Frontiers in oncology vol. 11 (2021): 657701. doi: https://doi.org/10.3389/fonc.2021.657701
Ramezani S, Parkhideh A, Bhattacharya PK, Farach-Carson MC, Harrington DA. Beyond Colonoscopy: Exploring New Cell Surface Biomarkers for Detection of Early, Heterogenous Colorectal Lesions. Front Oncol. 2021 Jul 05;11:657701. doi: 10.3389/fonc.2021.657701. eCollection 2021. PMID: 34290978; PMCID: PMC8287259.
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Changes in commuting behaviours in response to the COVID-19 pandemic in the UK.

Journal of transport & health

Harrington DM, Hadjiconstantinou M.
PMID: 34900585
J Transp Health. 2021 Dec 08;101313. doi: 10.1016/j.jth.2021.101313. Epub 2021 Dec 08.

BACKGROUND: The UK Government restrictions on non-essential work in response to the coronavirus disease 2019 (COVID-19) pandemic forced millions of working aged-adults into an unplanned lifestyle change. We present data on changes in commuting behaviour in response to COVID-19...

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Harrington DM, Hadjiconstantinou M. Changes in commuting behaviours in response to the COVID-19 pandemic in the UK. J Transp Health. 2021;101313doi: 10.1016/j.jth.2021.101313.
Harrington, D. M., & Hadjiconstantinou, M. (2021). Changes in commuting behaviours in response to the COVID-19 pandemic in the UK. Journal of transport & health, 101313. https://doi.org/10.1016/j.jth.2021.101313
Harrington, Deirdre M, and Hadjiconstantinou, Michelle. "Changes in commuting behaviours in response to the COVID-19 pandemic in the UK." Journal of transport & health vol. (2021): 101313. doi: https://doi.org/10.1016/j.jth.2021.101313
Harrington DM, Hadjiconstantinou M. Changes in commuting behaviours in response to the COVID-19 pandemic in the UK. J Transp Health. 2021 Dec 08;101313. doi: 10.1016/j.jth.2021.101313. Epub 2021 Dec 08. PMID: 34900585; PMCID: PMC8651520.
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Guanylate cyclase-C agonists as peripherally acting treatments of chronic visceral pain.

Trends in pharmacological sciences

Brierley SM, Grundy L, Castro J, Harrington AM, Hannig G, Camilleri M.
PMID: 34865885
Trends Pharmacol Sci. 2022 Feb;43(2):110-122. doi: 10.1016/j.tips.2021.11.002. Epub 2021 Dec 02.

Irritable bowel syndrome (IBS) is a chronic gastrointestinal disorder characterized by abdominal pain and altered bowel habit that affects ~11% of the global population. Over the past decade, preclinical and clinical studies have revealed a variety of novel mechanisms...

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Brierley SM, Grundy L, Castro J, et al. Guanylate cyclase-C agonists as peripherally acting treatments of chronic visceral pain. Trends Pharmacol Sci. 2021;43(2):110-122doi: 10.1016/j.tips.2021.11.002.
Brierley, S. M., Grundy, L., Castro, J., Harrington, A. M., Hannig, G., & Camilleri, M. (2022). Guanylate cyclase-C agonists as peripherally acting treatments of chronic visceral pain. Trends in pharmacological sciences, 43(2), 110-122. https://doi.org/10.1016/j.tips.2021.11.002
Brierley, Stuart M, et al. "Guanylate cyclase-C agonists as peripherally acting treatments of chronic visceral pain." Trends in pharmacological sciences vol. 43,2 (2022): 110-122. doi: https://doi.org/10.1016/j.tips.2021.11.002
Brierley SM, Grundy L, Castro J, Harrington AM, Hannig G, Camilleri M. Guanylate cyclase-C agonists as peripherally acting treatments of chronic visceral pain. Trends Pharmacol Sci. 2022 Feb;43(2):110-122. doi: 10.1016/j.tips.2021.11.002. Epub 2021 Dec 02. PMID: 34865885.
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Bringing hydrogel-based craniofacial therapies to the clinic.

Acta biomaterialia

Trubelja A, Kasper FK, Farach-Carson MC, Harrington DA.
PMID: 34743044
Acta Biomater. 2022 Jan 15;138:1-20. doi: 10.1016/j.actbio.2021.10.056. Epub 2021 Nov 04.

This review explores the evolution of the use of hydrogels for craniofacial soft tissue engineering, ranging in complexity from acellular injectable fillers to fabricated, cell-laden constructs with complex compositions and architectures. Addressing both in situ and ex vivo approaches,...

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Trubelja A, Kasper FK, Farach-Carson MC, et al. Bringing hydrogel-based craniofacial therapies to the clinic. Acta Biomater. 2021;138:1-20doi: 10.1016/j.actbio.2021.10.056.
Trubelja, A., Kasper, F. K., Farach-Carson, M. C., & Harrington, D. A. (2022). Bringing hydrogel-based craniofacial therapies to the clinic. Acta biomaterialia, 1381-20. https://doi.org/10.1016/j.actbio.2021.10.056
Trubelja, Alen, et al. "Bringing hydrogel-based craniofacial therapies to the clinic." Acta biomaterialia vol. 138 (2022): 1-20. doi: https://doi.org/10.1016/j.actbio.2021.10.056
Trubelja A, Kasper FK, Farach-Carson MC, Harrington DA. Bringing hydrogel-based craniofacial therapies to the clinic. Acta Biomater. 2022 Jan 15;138:1-20. doi: 10.1016/j.actbio.2021.10.056. Epub 2021 Nov 04. PMID: 34743044.
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Long-acting cabotegravir + rilpivirine for HIV-1 treatment: ATLAS week 96 results.

AIDS (London, England)

Swindells S, Lutz T, van Zyl L, Porteiro N, Stoll M, Mitha E, Shon A, Benn P, Huang JO, Harrington CM, Hove K, Ford SL, Talarico CL, Chounta V, Crauwels H, van Solingen-Ristea R, Vanveggel S, Margolis DA, Smith KY, Vandermeulen K, Spreen WR.
PMID: 34261093
AIDS. 2021 Jul 13; doi: 10.1097/QAD.0000000000003025. Epub 2021 Jul 13.

BACKGROUND: ATLAS (NCT02951052), a Phase 3, multicenter, open-label study, demonstrated that switching to injectable cabotegravir (CAB) + rilpivirine (RPV) long-acting (LA) dosed every 4 weeks was noninferior at Week (W) 48 to continuing three-drug daily oral antiretroviral therapy (CAR)....

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Swindells S, Lutz T, van Zyl L, et al. Long-acting cabotegravir + rilpivirine for HIV-1 treatment: ATLAS week 96 results. AIDS. 2021;doi: 10.1097/QAD.0000000000003025.
Swindells, S., Lutz, T., van Zyl, L., Porteiro, N., Stoll, M., Mitha, E., Shon, A., Benn, P., Huang, J. O., Harrington, C. M., Hove, K., Ford, S. L., Talarico, C. L., Chounta, V., Crauwels, H., van Solingen-Ristea, R., Vanveggel, S., Margolis, D. A., Smith, K. Y., Vandermeulen, K., & Spreen, W. R. (2021). Long-acting cabotegravir + rilpivirine for HIV-1 treatment: ATLAS week 96 results. AIDS (London, England), . https://doi.org/10.1097/QAD.0000000000003025
Swindells, Susan, et al. "Long-acting cabotegravir + rilpivirine for HIV-1 treatment: ATLAS week 96 results." AIDS (London, England) vol. (2021). doi: https://doi.org/10.1097/QAD.0000000000003025
Swindells S, Lutz T, van Zyl L, Porteiro N, Stoll M, Mitha E, Shon A, Benn P, Huang JO, Harrington CM, Hove K, Ford SL, Talarico CL, Chounta V, Crauwels H, van Solingen-Ristea R, Vanveggel S, Margolis DA, Smith KY, Vandermeulen K, Spreen WR. Long-acting cabotegravir + rilpivirine for HIV-1 treatment: ATLAS week 96 results. AIDS. 2021 Jul 13; doi: 10.1097/QAD.0000000000003025. Epub 2021 Jul 13. PMID: 34261093.
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Dietary Habits and Medications to Control Hypertension Among Women of Child-Bearing Age in the United States from 2001 to 2016.

American journal of hypertension

Kovell LC, Maxner B, Ayturk D, Moore Simas TA, Harrington CM, McManus DD, Gardiner P, Aurigemma GP, Juraschek SP.
PMID: 33693539
Am J Hypertens. 2021 Sep 22;34(9):919-928. doi: 10.1093/ajh/hpab041.

BACKGROUND: Hypertension (HTN) in pregnancy is a leading cause of maternal morbidity and mortality in the United States. Although the Dietary Approaches to Stop Hypertension (DASH) diet is recommended for all adults with HTN, rates of DASH adherence and...

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Kovell LC, Maxner B, Ayturk D, et al. Dietary Habits and Medications to Control Hypertension Among Women of Child-Bearing Age in the United States from 2001 to 2016. Am J Hypertens. 2021;34(9):919-928doi: 10.1093/ajh/hpab041.
Kovell, L. C., Maxner, B., Ayturk, D., Moore Simas, T. A., Harrington, C. M., McManus, D. D., Gardiner, P., Aurigemma, G. P., & Juraschek, S. P. (2021). Dietary Habits and Medications to Control Hypertension Among Women of Child-Bearing Age in the United States from 2001 to 2016. American journal of hypertension, 34(9), 919-928. https://doi.org/10.1093/ajh/hpab041
Kovell, Lara C, et al. "Dietary Habits and Medications to Control Hypertension Among Women of Child-Bearing Age in the United States from 2001 to 2016." American journal of hypertension vol. 34,9 (2021): 919-928. doi: https://doi.org/10.1093/ajh/hpab041
Kovell LC, Maxner B, Ayturk D, Moore Simas TA, Harrington CM, McManus DD, Gardiner P, Aurigemma GP, Juraschek SP. Dietary Habits and Medications to Control Hypertension Among Women of Child-Bearing Age in the United States from 2001 to 2016. Am J Hypertens. 2021 Sep 22;34(9):919-928. doi: 10.1093/ajh/hpab041. PMID: 33693539; PMCID: PMC8457430.
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OGT Regulates Mitochondrial Biogenesis and Function via Diabetes Susceptibility Gene Pdx1.

Diabetes

Mohan R, Jo S, Lockridge A, Ferrington DA, Murray K, Eschenlauer A, Bernal-Mizrachi E, Fujitani Y, Alejandro EU.
PMID: 34462257
Diabetes. 2021 Nov;70(11):2608-2625. doi: 10.2337/db21-0468. Epub 2021 Aug 30.

No abstract available.

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Mohan R, Jo S, Lockridge A, et al. OGT Regulates Mitochondrial Biogenesis and Function via Diabetes Susceptibility Gene Pdx1. Diabetes. 2021;70(11):2608-2625doi: 10.2337/db21-0468.
Mohan, R., Jo, S., Lockridge, A., Ferrington, D. A., Murray, K., Eschenlauer, A., Bernal-Mizrachi, E., Fujitani, Y., & Alejandro, E. U. (2021). OGT Regulates Mitochondrial Biogenesis and Function via Diabetes Susceptibility Gene Pdx1. Diabetes, 70(11), 2608-2625. https://doi.org/10.2337/db21-0468
Mohan, Ramkumar, et al. "OGT Regulates Mitochondrial Biogenesis and Function via Diabetes Susceptibility Gene Pdx1." Diabetes vol. 70,11 (2021): 2608-2625. doi: https://doi.org/10.2337/db21-0468
Mohan R, Jo S, Lockridge A, Ferrington DA, Murray K, Eschenlauer A, Bernal-Mizrachi E, Fujitani Y, Alejandro EU. OGT Regulates Mitochondrial Biogenesis and Function via Diabetes Susceptibility Gene Pdx1. Diabetes. 2021 Nov;70(11):2608-2625. doi: 10.2337/db21-0468. Epub 2021 Aug 30. PMID: 34462257; PMCID: PMC8564412.
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Genome Sequences of Gordonia rubripertincta Bacteriophages Jellybones and NHagos.

Microbiology resource announcements

Harrington DL, Stevens JL, Johnson MJ, Pochiro SJ, Moriarty MM, Robertson ME, Sanchez A, Whitby OG, Kimberley KW, McKenna CC, Theoret JR, Windsor EJ, Yoon EJ.
PMID: 33004457
Microbiol Resour Announc. 2020 Oct 01;9(40). doi: 10.1128/MRA.00935-20.

Jellybones and NHagos are bacteriophages that were identified in the host bacterium

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Harrington DL, Stevens JL, Johnson MJ, et al. Genome Sequences of Gordonia rubripertincta Bacteriophages Jellybones and NHagos. Microbiol Resour Announc. 2020;9(40)doi: 10.1128/MRA.00935-20.
Harrington, D. L., Stevens, J. L., Johnson, M. J., Pochiro, S. J., Moriarty, M. M., Robertson, M. E., Sanchez, A., Whitby, O. G., Kimberley, K. W., McKenna, C. C., Theoret, J. R., Windsor, E. J., & Yoon, E. J. (2020). Genome Sequences of Gordonia rubripertincta Bacteriophages Jellybones and NHagos. Microbiology resource announcements, 9(40), . https://doi.org/10.1128/MRA.00935-20
Harrington, D'Andrew L, et al. "Genome Sequences of Gordonia rubripertincta Bacteriophages Jellybones and NHagos." Microbiology resource announcements vol. 9,40 (2020). doi: https://doi.org/10.1128/MRA.00935-20
Harrington DL, Stevens JL, Johnson MJ, Pochiro SJ, Moriarty MM, Robertson ME, Sanchez A, Whitby OG, Kimberley KW, McKenna CC, Theoret JR, Windsor EJ, Yoon EJ. Genome Sequences of Gordonia rubripertincta Bacteriophages Jellybones and NHagos. Microbiol Resour Announc. 2020 Oct 01;9(40). doi: 10.1128/MRA.00935-20. PMID: 33004457; PMCID: PMC7530929.
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Glutathione Metabolism and the Novel Role of Mitochondrial GSH in Retinal Degeneration.

Antioxidants (Basel, Switzerland)

Sreekumar PG, Ferrington DA, Kannan R.
PMID: 33923192
Antioxidants (Basel). 2021 Apr 24;10(5). doi: 10.3390/antiox10050661.

Glutathione (GSH) is present ubiquitously, and its role as a crucial cellular antioxidant in tissues, including the retina, is well established. GSH's antioxidant function arises from its ability to scavenge reactive oxygen species or to serve as an essential...

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Sreekumar PG, Ferrington DA, Kannan R. Glutathione Metabolism and the Novel Role of Mitochondrial GSH in Retinal Degeneration. Antioxidants (Basel). 2021;10(5)doi: 10.3390/antiox10050661.
Sreekumar, P. G., Ferrington, D. A., & Kannan, R. (2021). Glutathione Metabolism and the Novel Role of Mitochondrial GSH in Retinal Degeneration. Antioxidants (Basel, Switzerland), 10(5), . https://doi.org/10.3390/antiox10050661
Sreekumar, Parameswaran G, et al. "Glutathione Metabolism and the Novel Role of Mitochondrial GSH in Retinal Degeneration." Antioxidants (Basel, Switzerland) vol. 10,5 (2021). doi: https://doi.org/10.3390/antiox10050661
Sreekumar PG, Ferrington DA, Kannan R. Glutathione Metabolism and the Novel Role of Mitochondrial GSH in Retinal Degeneration. Antioxidants (Basel). 2021 Apr 24;10(5). doi: 10.3390/antiox10050661. PMID: 33923192; PMCID: PMC8146950.
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Characterizing college science instruction: The Three-Dimensional Learning Observation Protocol.

PloS one

Bain K, Bender L, Bergeron P, Caballero MD, Carmel JH, Duffy EM, Ebert-May D, Fata-Hartley CL, Herrington DG, Laverty JT, Matz RL, Nelson PC, Posey LA, Stoltzfus JR, Stowe RL, Sweeder RD, Tessmer SH, Underwood SM, Urban-Lurain M, Cooper MM.
PMID: 32544166
PLoS One. 2020 Jun 16;15(6):e0234640. doi: 10.1371/journal.pone.0234640. eCollection 2020.

The importance of improving STEM education is of perennial interest, and to this end, the education community needs ways to characterize transformation efforts. Three-dimensional learning (3DL) is one such approach to transformation, in which core ideas of the discipline,...

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Bain K, Bender L, Bergeron P, et al. Characterizing college science instruction: The Three-Dimensional Learning Observation Protocol. PLoS One. 2020;15(6):e0234640doi: 10.1371/journal.pone.0234640.
Bain, K., Bender, L., Bergeron, P., Caballero, M. D., Carmel, J. H., Duffy, E. M., Ebert-May, D., Fata-Hartley, C. L., Herrington, D. G., Laverty, J. T., Matz, R. L., Nelson, P. C., Posey, L. A., Stoltzfus, J. R., Stowe, R. L., Sweeder, R. D., Tessmer, S. H., Underwood, S. M., Urban-Lurain, M., & Cooper, M. M. (2020). Characterizing college science instruction: The Three-Dimensional Learning Observation Protocol. PloS one, 15(6), e0234640. https://doi.org/10.1371/journal.pone.0234640
Bain, Kinsey, et al. "Characterizing college science instruction: The Three-Dimensional Learning Observation Protocol." PloS one vol. 15,6 (2020): e0234640. doi: https://doi.org/10.1371/journal.pone.0234640
Bain K, Bender L, Bergeron P, Caballero MD, Carmel JH, Duffy EM, Ebert-May D, Fata-Hartley CL, Herrington DG, Laverty JT, Matz RL, Nelson PC, Posey LA, Stoltzfus JR, Stowe RL, Sweeder RD, Tessmer SH, Underwood SM, Urban-Lurain M, Cooper MM. Characterizing college science instruction: The Three-Dimensional Learning Observation Protocol. PLoS One. 2020 Jun 16;15(6):e0234640. doi: 10.1371/journal.pone.0234640. eCollection 2020. PMID: 32544166; PMCID: PMC7297354.
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Dissociation of Neural Mechanisms for Intersensory Timing Deficits in Parkinson's Disease.

Timing & time perception (Leiden, Netherlands)

Harrington DL, Castillo GN, Reed JD, Song DD, Litvan I, Lee RR.
PMID: 32432026
Timing Time Percept. 2014 May 19;2(2):145-168. doi: 10.1163/22134468-00002025.

This study investigated the ability of individuals with Parkinson's disease (PD) to synthesize temporal information across the senses, namely audition and vision. Auditory signals (A) are perceived as lasting longer than visual signals (V) when they are compared together,...

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Harrington DL, Castillo GN, Reed JD, et al. Dissociation of Neural Mechanisms for Intersensory Timing Deficits in Parkinson's Disease. Timing Time Percept. 2014;2(2):145-168doi: 10.1163/22134468-00002025.
Harrington, D. L., Castillo, G. N., Reed, J. D., Song, D. D., Litvan, I., & Lee, R. R. (2014). Dissociation of Neural Mechanisms for Intersensory Timing Deficits in Parkinson's Disease. Timing & time perception (Leiden, Netherlands), 2(2), 145-168. https://doi.org/10.1163/22134468-00002025
Harrington, Deborah L, et al. "Dissociation of Neural Mechanisms for Intersensory Timing Deficits in Parkinson's Disease." Timing & time perception (Leiden, Netherlands) vol. 2,2 (2014): 145-168. doi: https://doi.org/10.1163/22134468-00002025
Harrington DL, Castillo GN, Reed JD, Song DD, Litvan I, Lee RR. Dissociation of Neural Mechanisms for Intersensory Timing Deficits in Parkinson's Disease. Timing Time Percept. 2014 May 19;2(2):145-168. doi: 10.1163/22134468-00002025. PMID: 32432026; PMCID: PMC7236402.
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Metabolic Syndrome Derived from Principal Component Analysis and Incident Cardiovascular Events: The Multi Ethnic Study of Atherosclerosis (MESA) and Health, Aging, and Body Composition (Health ABC).

Cardiology research and practice

Agarwal S, Jacobs DR, Vaidya D, Sibley CT, Jorgensen NW, Rotter JI, Chen YD, Liu Y, Andrews JS, Kritchevsky S, Goodpaster B, Kanaya A, Newman AB, Simonsick EM, Herrington DM.
PMID: 22536533
Cardiol Res Pract. 2012;2012:919425. doi: 10.1155/2012/919425. Epub 2012 Mar 21.

Background. The NCEP metabolic syndrome (MetS) is a combination of dichotomized interrelated risk factors from predominantly Caucasian populations. We propose a continuous MetS score based on principal component analysis (PCA) of the same risk factors in a multiethnic cohort...

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Agarwal S, Jacobs DR, Vaidya D, et al. Metabolic Syndrome Derived from Principal Component Analysis and Incident Cardiovascular Events: The Multi Ethnic Study of Atherosclerosis (MESA) and Health, Aging, and Body Composition (Health ABC). Cardiol Res Pract. 2012;2012:919425doi: 10.1155/2012/919425.
Agarwal, S., Jacobs, D. R., Vaidya, D., Sibley, C. T., Jorgensen, N. W., Rotter, J. I., Chen, Y. D., Liu, Y., Andrews, J. S., Kritchevsky, S., Goodpaster, B., Kanaya, A., Newman, A. B., Simonsick, E. M., & Herrington, D. M. (2012). Metabolic Syndrome Derived from Principal Component Analysis and Incident Cardiovascular Events: The Multi Ethnic Study of Atherosclerosis (MESA) and Health, Aging, and Body Composition (Health ABC). Cardiology research and practice, 2012919425. https://doi.org/10.1155/2012/919425
Agarwal, Subhashish, et al. "Metabolic Syndrome Derived from Principal Component Analysis and Incident Cardiovascular Events: The Multi Ethnic Study of Atherosclerosis (MESA) and Health, Aging, and Body Composition (Health ABC)." Cardiology research and practice vol. 2012 (2012): 919425. doi: https://doi.org/10.1155/2012/919425
Agarwal S, Jacobs DR, Vaidya D, Sibley CT, Jorgensen NW, Rotter JI, Chen YD, Liu Y, Andrews JS, Kritchevsky S, Goodpaster B, Kanaya A, Newman AB, Simonsick EM, Herrington DM. Metabolic Syndrome Derived from Principal Component Analysis and Incident Cardiovascular Events: The Multi Ethnic Study of Atherosclerosis (MESA) and Health, Aging, and Body Composition (Health ABC). Cardiol Res Pract. 2012;2012:919425. doi: 10.1155/2012/919425. Epub 2012 Mar 21. PMID: 22536533; PMCID: PMC3318892.
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