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Showing 13 to 24 of 163 entries
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Modulation of firing and synaptic transmission of serotonergic neurons by intrinsic G protein-coupled receptors and ion channels.

Frontiers in integrative neuroscience

Maejima T, Masseck OA, Mark MD, Herlitze S.
PMID: 23734105
Front Integr Neurosci. 2013 May 23;7:40. doi: 10.3389/fnint.2013.00040. eCollection 2013.

Serotonergic neurons project to virtually all regions of the central nervous system and are consequently involved in many critical physiological functions such as mood, sexual behavior, feeding, sleep/wake cycle, memory, cognition, blood pressure regulation, breathing, and reproductive success. Therefore,...

Molecular dynamics simulations of polyelectrolyte brushes under poor solvent conditions: origins of bundle formation.

The Journal of chemical physics

He GL, Merlitz H, Sommer JU.
PMID: 24628209
J Chem Phys. 2014 Mar 14;140(10):104911. doi: 10.1063/1.4867466.

Molecular dynamics simulations are applied to investigate salt-free planar polyelectrolyte brushes under poor solvent conditions. Starting above the Θ-point with a homogeneous brush and then gradually reducing the temperature, the polymers initially display a lateral structure formation, forming vertical...

Polymer-induced inverse-temperature crystallization of nanoparticles on a substrate.

ACS nano

Cao XZ, Merlitz H, Wu CX, Sommer JU.
PMID: 24098894
ACS Nano. 2013 Nov 26;7(11):9920-6. doi: 10.1021/nn4037738. Epub 2013 Oct 07.

Using molecular dynamics simulations, we study the properties of liquid state polymer-nanoparticle composites confined between two parallel substrates, with an attractive polymer-substrate interaction. Polymers are in the semidilute regime at concentrations far above the overlap point, and nanoparticles are...

Toward Developing Laboratory-Based Parent-Adolescent Conflict Discussion Tasks that Consistently Elicit Adolescent Conflict-Related Stress Responses: Support from Physiology and Observed Behavior.

Journal of child and family studies

Thomas SA, Wilson T, Jain A, Deros DE, Um M, Hurwitz J, Jacobs I, Myerberg L, Ehrlich KB, Dunn EJ, Aldao A, Stadnik R, De Los Reyes A.
PMID: 29249892
J Child Fam Stud. 2017 Dec;26(12):3288-3302. doi: 10.1007/s10826-017-0844-z. Epub 2017 Aug 02.

Parent-adolescent conflict poses risk for youth maladjustment. One potential mechanism of this risk is that stress in the form of increased arousal during conflict interactions results in adolescents' impaired decision-making. However, eliciting consistent adolescent stress responses within laboratory-based tasks...

Mixed brush made of 4-arm stars and linear chains: MD simulations.

The Journal of chemical physics

Su CF, Merlitz H, Wu CX, Sommer JU.
PMID: 27984868
J Chem Phys. 2016 Dec 21;145(23):234905. doi: 10.1063/1.4971379.

We investigate the structural properties of binary polymer brushes, composed of functional 4-armed star polymers and chemically identical linear polymers of different molecular weights. The molecular dynamics simulations confirm recent self-consistent field studies, in which a considerable potential of...

Interplay of LIS1 and MeCP2: Interactions and Implications With the Neurodevelopmental Disorders Lissencephaly and Rett Syndrome.

Frontiers in cellular neuroscience

Keidar L, Gerlitz G, Kshirsagar A, Tsoory M, Olender T, Wang X, Yang Y, Chen YS, Yang YG, Voineagu I, Reiner O.
PMID: 31474834
Front Cell Neurosci. 2019 Aug 14;13:370. doi: 10.3389/fncel.2019.00370. eCollection 2019.

No abstract available.

Non-synchronization of lattice and carrier temperatures in light-emitting diodes.

Scientific reports

Zhang J, Shih T, Lu Y, Merlitz H, Chang RR, Chen Z.
PMID: 26785685
Sci Rep. 2016 Jan 20;6:19539. doi: 10.1038/srep19539.

Pulse implementation or switching-off (PISO) of electrical currents has become a common operation in junction-temperature (Tj) measurements for semiconductor devices since 2004. Here we have experimentally discovered a substantial discrepancy between Tj values with, and without, PISO (e.g., 36.8...

Role of Complement Activation in Allograft Inflammation.

Current transplantation reports

Chun N, Horwitz J, Heeger PS.
PMID: 31673484
Curr Transplant Rep. 2019 Mar;6(1):52-59. doi: 10.1007/s40472-019-0224-2. Epub 2019 Jan 15.

PURPOSE: Novel paradigms have broadened our understanding of mechanisms through which complement mediates allograft inflammation/injury. Herein we review advances in the field and highlight therapeutic implications.RECENT FINDINGS: Pre-clinical and translational human trials have elucidated complement-dependent mechanisms of post-transplant ischemia-reperfusion...

Design of binary polymer brushes with tuneable functionality.

Soft matter

Bos I, Merlitz H, Rosenthal A, Uhlmann P, Sommer JU.
PMID: 30132780
Soft Matter. 2018 Sep 11;14(35):7237-7245. doi: 10.1039/c8sm01108g.

Using coarse grained molecular dynamics simulations, we study how functionalized binary brushes may be used to create surfaces whose functionality can be tuned. Our model brushes consist of a mixture of nonresponsive polymers with functionalized responsive polymers. The functional...

Limited need for hospital resources among patients brought to hospital by the emergency medical services.

BMC emergency medicine

Magnusson C, Ryge H, Scott F, Herlitz J, Axelsson C.
PMID: 34911447
BMC Emerg Med. 2021 Dec 15;21(1):156. doi: 10.1186/s12873-021-00549-6.

BACKGROUND: In Sweden, the majority of patients who are transported to hospital by the emergency medical services (EMS) are relatively old and the majority suffer from comorbidity. About half these patients are admitted to a hospital ward and will...

8-hydroxyquinoline and quinazoline derivatives as potential new alternatives to combat Candida spp. biofilm.

Letters in applied microbiology

Reginatto P, Joaquim AR, Rocha DA, Berlitz SJ, Külkamp-Guerreiro IC, De Andrade SF, Fuentefria AM.
PMID: 34822194
Lett Appl Microbiol. 2021 Nov 25; doi: 10.1111/lam.13607. Epub 2021 Nov 25.

Often associated to the colonization by Candida spp. biofilm, the catheter-related infections are a serious health problem since the absence of a specific therapy. Hence, the main objective of this work was to evaluate the activity of 8-hydroxyquinoline and...

Inequalities in Income and Education Are Associated With Survival Differences After Out-of-Hospital Cardiac Arrest: Nationwide Observational Study.

Circulation

Jonsson M, Härkönen J, Ljungman P, Nordberg P, Ringh M, Hirlekar G, Rawshani A, Herlitz J, Ljung R, Hollenberg J.
PMID: 34767462
Circulation. 2021 Dec 14;144(24):1915-1925. doi: 10.1161/CIRCULATIONAHA.121.056012. Epub 2021 Nov 12.

BACKGROUND: Despite the acknowledged importance of socioeconomic factors as regards cardiovascular disease onset and survival, the relationship between individual-level socioeconomic factors and survival after out-of-hospital cardiac arrest is not established. Our aim was to investigate whether socioeconomic variables are...

Showing 13 to 24 of 163 entries