Advanced Search
Display options
Filter resources
Text Availability
Article type
Publication date
Species
Language
Sex
Age
Showing 25 to 36 of 200 entries
Sorted by: Best Match Show Resources per page
PLCG1 is required for AML1-ETO leukemia stem cell self-renewal.

Blood

Schnoeder TM, Schwarzer A, Jayavelu AK, Hsu CJ, Kirkpatrick J, Döhner K, Perner F, Eifert T, Huber N, Arreba-Tutusaus P, Dolnik A, Assi SA, Nafria M, Jiang L, Dai YT, Chen Z, Chen SJ, Kellaway SG, Ptasinska A, Ng ES, Stanley EG, Elefanty AG, Buschbeck M, Bierhoff H, Brodt S, Matziolis G, Fischer KD, Hochhaus A, Chen CW, Heidenreich O, Mann M, Lane SW, Bullinger L, Ori A, Eyss BV, Bonifer C, Heidel F.
PMID: 34695195
Blood. 2021 Oct 25; doi: 10.1182/blood.2021012778. Epub 2021 Oct 25.

In an effort to identify novel drugs targeting fusion-oncogene induced acute myeloid leukemia (AML), we performed high-resolution proteomic analysis. In AML1-ETO (AE) driven AML we uncovered a de-regulation of phospholipase C (PLC) signaling. We identified PLCgamma 1 (PLCG1) as...

Cite
Schnoeder TM, Schwarzer A, Jayavelu AK, et al. PLCG1 is required for AML1-ETO leukemia stem cell self-renewal. Blood. 2021;doi: 10.1182/blood.2021012778.
Schnoeder, T. M., Schwarzer, A., Jayavelu, A. K., Hsu, C. J., Kirkpatrick, J., Döhner, K., Perner, F., Eifert, T., Huber, N., Arreba-Tutusaus, P., Dolnik, A., Assi, S. A., Nafria, M., Jiang, L., Dai, Y. T., Chen, Z., Chen, S. J., Kellaway, S. G., Ptasinska, A., Ng, E. S., Stanley, E. G., Elefanty, A. G., Buschbeck, M., Bierhoff, H., Brodt, S., Matziolis, G., Fischer, K. D., Hochhaus, A., Chen, C. W., Heidenreich, O., Mann, M., Lane, S. W., Bullinger, L., Ori, A., Eyss, B. V., Bonifer, C., & Heidel, F. (2021). PLCG1 is required for AML1-ETO leukemia stem cell self-renewal. Blood, . https://doi.org/10.1182/blood.2021012778
Schnoeder, Tina M, et al. "PLCG1 is required for AML1-ETO leukemia stem cell self-renewal." Blood vol. (2021). doi: https://doi.org/10.1182/blood.2021012778
Schnoeder TM, Schwarzer A, Jayavelu AK, Hsu CJ, Kirkpatrick J, Döhner K, Perner F, Eifert T, Huber N, Arreba-Tutusaus P, Dolnik A, Assi SA, Nafria M, Jiang L, Dai YT, Chen Z, Chen SJ, Kellaway SG, Ptasinska A, Ng ES, Stanley EG, Elefanty AG, Buschbeck M, Bierhoff H, Brodt S, Matziolis G, Fischer KD, Hochhaus A, Chen CW, Heidenreich O, Mann M, Lane SW, Bullinger L, Ori A, Eyss BV, Bonifer C, Heidel F. PLCG1 is required for AML1-ETO leukemia stem cell self-renewal. Blood. 2021 Oct 25; doi: 10.1182/blood.2021012778. Epub 2021 Oct 25. PMID: 34695195.
Copy Download .nbib Format: NLM
Wheat growth responses to soil mechanical impedance are dependent on phosphorus supply.

Soil & tillage research

Wang X, Shen J, Hedden P, Phillips AL, Thomas SG, Ge Y, Ashton RW, Whalley WR.
PMID: 33390631
Soil Tillage Res. 2021 Jan;205:104754. doi: 10.1016/j.still.2020.104754.

Increased mechanical impedance induced by soil drying or compaction causes reduction in plant growth and crop yield. However, how mechanical impedance interacts with nutrient stress has been largely unknown. Here, we investigated the effect of mechanical impedance on the...

Cite
Wang X, Shen J, Hedden P, et al. Wheat growth responses to soil mechanical impedance are dependent on phosphorus supply. Soil Tillage Res. 2021;205:104754doi: 10.1016/j.still.2020.104754.
Wang, X., Shen, J., Hedden, P., Phillips, A. L., Thomas, S. G., Ge, Y., Ashton, R. W., & Whalley, W. R. (2021). Wheat growth responses to soil mechanical impedance are dependent on phosphorus supply. Soil & tillage research, 205104754. https://doi.org/10.1016/j.still.2020.104754
Wang, Xin, et al. "Wheat growth responses to soil mechanical impedance are dependent on phosphorus supply." Soil & tillage research vol. 205 (2021): 104754. doi: https://doi.org/10.1016/j.still.2020.104754
Wang X, Shen J, Hedden P, Phillips AL, Thomas SG, Ge Y, Ashton RW, Whalley WR. Wheat growth responses to soil mechanical impedance are dependent on phosphorus supply. Soil Tillage Res. 2021 Jan;205:104754. doi: 10.1016/j.still.2020.104754. PMID: 33390631; PMCID: PMC7729824.
Copy Download .nbib Format: NLM
Connectivity Patterns of Deep Brain Stimulation Targets in Patients with Gilles de la Tourette Syndrome.

Brain sciences

Heiden P, Hoevels M, Bayram D, Baldermann JC, Schüller T, Huys D, Visser-Vandewalle V, Andrade P.
PMID: 33440771
Brain Sci. 2021 Jan 11;11(1). doi: 10.3390/brainsci11010087.

Since 1999, several targets for deep brain stimulation (DBS) in Gilles de la Tourette syndrome (GTS) have emerged showing similar success rates. Studies using different tractography techniques have identified connectivity profiles associated with a better outcome for individual targets....

Cite
Heiden P, Hoevels M, Bayram D, et al. Connectivity Patterns of Deep Brain Stimulation Targets in Patients with Gilles de la Tourette Syndrome. Brain Sci. 2021;11(1)doi: 10.3390/brainsci11010087.
Heiden, P., Hoevels, M., Bayram, D., Baldermann, J. C., Schüller, T., Huys, D., Visser-Vandewalle, V., & Andrade, P. (2021). Connectivity Patterns of Deep Brain Stimulation Targets in Patients with Gilles de la Tourette Syndrome. Brain sciences, 11(1), . https://doi.org/10.3390/brainsci11010087
Heiden, Petra, et al. "Connectivity Patterns of Deep Brain Stimulation Targets in Patients with Gilles de la Tourette Syndrome." Brain sciences vol. 11,1 (2021). doi: https://doi.org/10.3390/brainsci11010087
Heiden P, Hoevels M, Bayram D, Baldermann JC, Schüller T, Huys D, Visser-Vandewalle V, Andrade P. Connectivity Patterns of Deep Brain Stimulation Targets in Patients with Gilles de la Tourette Syndrome. Brain Sci. 2021 Jan 11;11(1). doi: 10.3390/brainsci11010087. PMID: 33440771; PMCID: PMC7826809.
Copy Download .nbib Format: NLM
Hyperprogression fortgeschrittener Melanomerkrankung unter Pembrolizumab adjuvant.

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG

Geidel G, Ammann NL, Schneider SW, Gebhardt C.
PMID: 33835653
J Dtsch Dermatol Ges. 2021 Jul;19:37-39. doi: 10.1111/ddg.14480.

No abstract available.

Cite
Geidel G, Ammann NL, Schneider SW, et al. Hyperprogression fortgeschrittener Melanomerkrankung unter Pembrolizumab adjuvant. J Dtsch Dermatol Ges. 2021;19:37-39doi: 10.1111/ddg.14480.
Geidel, G., Ammann, N. L., Schneider, S. W., & Gebhardt, C. (2021). Hyperprogression fortgeschrittener Melanomerkrankung unter Pembrolizumab adjuvant. Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 1937-39. https://doi.org/10.1111/ddg.14480
Geidel, Glenn, et al. "Hyperprogression fortgeschrittener Melanomerkrankung unter Pembrolizumab adjuvant." Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG vol. 19 (2021): 37-39. doi: https://doi.org/10.1111/ddg.14480
Geidel G, Ammann NL, Schneider SW, Gebhardt C. Hyperprogression fortgeschrittener Melanomerkrankung unter Pembrolizumab adjuvant. J Dtsch Dermatol Ges. 2021 Jul;19:37-39. doi: 10.1111/ddg.14480. PMID: 33835653.
Copy Download .nbib Format: NLM
Potential Benefits and Risks Resulting From the Introduction of Health Apps and Wearables Into the German Statutory Health Care System: Scoping Review.

JMIR mHealth and uHealth

Heidel A, Hagist C.
PMID: 32965231
JMIR Mhealth Uhealth. 2020 Sep 23;8(9):e16444. doi: 10.2196/16444.

BACKGROUND: Germany is the first country worldwide that has introduced a digital care act as an incentive system to enhance the use of digital health devices, namely health apps and wearables, among its population. The act allows physicians to...

Cite
Heidel A, Hagist C. Potential Benefits and Risks Resulting From the Introduction of Health Apps and Wearables Into the German Statutory Health Care System: Scoping Review. JMIR Mhealth Uhealth. 2020;8(9):e16444doi: 10.2196/16444.
Heidel, A., & Hagist, C. (2020). Potential Benefits and Risks Resulting From the Introduction of Health Apps and Wearables Into the German Statutory Health Care System: Scoping Review. JMIR mHealth and uHealth, 8(9), e16444. https://doi.org/10.2196/16444
Heidel, Alexandra, and Hagist, Christian. "Potential Benefits and Risks Resulting From the Introduction of Health Apps and Wearables Into the German Statutory Health Care System: Scoping Review." JMIR mHealth and uHealth vol. 8,9 (2020): e16444. doi: https://doi.org/10.2196/16444
Heidel A, Hagist C. Potential Benefits and Risks Resulting From the Introduction of Health Apps and Wearables Into the German Statutory Health Care System: Scoping Review. JMIR Mhealth Uhealth. 2020 Sep 23;8(9):e16444. doi: 10.2196/16444. PMID: 32965231; PMCID: PMC7542416.
Copy Download .nbib Format: NLM
Unpacking Medical Students' Mixed Engagement in Health Systems Science Education.

Teaching and learning in medicine

Gonzalo JD, Davis C, Thompson BM, Haidet P.
PMID: 31875724
Teach Learn Med. 2020 Jun-Jul;32(3):250-258. doi: 10.1080/10401334.2019.1704765. Epub 2019 Dec 26.

No abstract available.

Cite
Gonzalo JD, Davis C, Thompson BM, et al. Unpacking Medical Students' Mixed Engagement in Health Systems Science Education. Teach Learn Med. 2019;32(3):250-258doi: 10.1080/10401334.2019.1704765.
Gonzalo, J. D., Davis, C., Thompson, B. M., & Haidet, P. (2020). Unpacking Medical Students' Mixed Engagement in Health Systems Science Education. Teaching and learning in medicine, 32(3), 250-258. https://doi.org/10.1080/10401334.2019.1704765
Gonzalo, Jed D, et al. "Unpacking Medical Students' Mixed Engagement in Health Systems Science Education." Teaching and learning in medicine vol. 32,3 (2020): 250-258. doi: https://doi.org/10.1080/10401334.2019.1704765
Gonzalo JD, Davis C, Thompson BM, Haidet P. Unpacking Medical Students' Mixed Engagement in Health Systems Science Education. Teach Learn Med. 2020 Jun-Jul;32(3):250-258. doi: 10.1080/10401334.2019.1704765. Epub 2019 Dec 26. PMID: 31875724.
Copy Download .nbib Format: NLM
A case report of a late left atrial appendage perforation 4 months after occluder implant: reason for or caused by a resuscitation?.

European heart journal. Case reports

Schenke K, Geidel S, Keller C, Grönefeld G.
PMID: 31911986
Eur Heart J Case Rep. 2019 Dec;3(4):1-4. doi: 10.1093/ehjcr/ytz170. Epub 2019 Oct 04.

BACKGROUND: Atrial fibrillation (AF) is a common disease and can lead to cardioembolic stroke. Stroke prevention according to the CHACASE SUMMARY: A 75-year-old man with AF and recurrent gastrointestinal bleedings was referred for an interventional closure of the LAA....

Cite
Schenke K, Geidel S, Keller C, et al. A case report of a late left atrial appendage perforation 4 months after occluder implant: reason for or caused by a resuscitation?. Eur Heart J Case Rep. 2019;3(4):1-4doi: 10.1093/ehjcr/ytz170.
Schenke, K., Geidel, S., Keller, C., & Grönefeld, G. (2019). A case report of a late left atrial appendage perforation 4 months after occluder implant: reason for or caused by a resuscitation?. European heart journal. Case reports, 3(4), 1-4. https://doi.org/10.1093/ehjcr/ytz170
Schenke, Karsten, et al. "A case report of a late left atrial appendage perforation 4 months after occluder implant: reason for or caused by a resuscitation?." European heart journal. Case reports vol. 3,4 (2019): 1-4. doi: https://doi.org/10.1093/ehjcr/ytz170
Schenke K, Geidel S, Keller C, Grönefeld G. A case report of a late left atrial appendage perforation 4 months after occluder implant: reason for or caused by a resuscitation?. Eur Heart J Case Rep. 2019 Dec;3(4):1-4. doi: 10.1093/ehjcr/ytz170. Epub 2019 Oct 04. PMID: 31911986; PMCID: PMC6939804.
Copy Download .nbib Format: NLM
The Transcriptional Repressor Orphan Nuclear Receptor TLX Is Responsive to Xanthines.

ACS pharmacology & translational science

Faudone G, Kilu W, Ni X, Chaikuad A, Sreeramulu S, Heitel P, Schwalbe H, Knapp S, Schubert-Zsilavecz M, Heering J, Merk D.
PMID: 34927011
ACS Pharmacol Transl Sci. 2021 Nov 23;4(6):1794-1807. doi: 10.1021/acsptsci.1c00195. eCollection 2021 Dec 10.

The orphan nuclear receptor tailless homologue (TLX) is expressed almost exclusively in neural stem cells acting as an essential factor for their survival and is hence considered as a promising drug target in neurodegeneration. However, few studies have characterized...

Cite
Faudone G, Kilu W, Ni X, et al. The Transcriptional Repressor Orphan Nuclear Receptor TLX Is Responsive to Xanthines. ACS Pharmacol Transl Sci. 2021;4(6):1794-1807doi: 10.1021/acsptsci.1c00195.
Faudone, G., Kilu, W., Ni, X., Chaikuad, A., Sreeramulu, S., Heitel, P., Schwalbe, H., Knapp, S., Schubert-Zsilavecz, M., Heering, J., & Merk, D. (2021). The Transcriptional Repressor Orphan Nuclear Receptor TLX Is Responsive to Xanthines. ACS pharmacology & translational science, 4(6), 1794-1807. https://doi.org/10.1021/acsptsci.1c00195
Faudone, Giuseppe, et al. "The Transcriptional Repressor Orphan Nuclear Receptor TLX Is Responsive to Xanthines." ACS pharmacology & translational science vol. 4,6 (2021): 1794-1807. doi: https://doi.org/10.1021/acsptsci.1c00195
Faudone G, Kilu W, Ni X, Chaikuad A, Sreeramulu S, Heitel P, Schwalbe H, Knapp S, Schubert-Zsilavecz M, Heering J, Merk D. The Transcriptional Repressor Orphan Nuclear Receptor TLX Is Responsive to Xanthines. ACS Pharmacol Transl Sci. 2021 Nov 23;4(6):1794-1807. doi: 10.1021/acsptsci.1c00195. eCollection 2021 Dec 10. PMID: 34927011; PMCID: PMC8669710.
Copy Download .nbib Format: NLM
How Are the Arts and Humanities Used in Medical Education? Results of a Scoping Review.

Academic medicine : journal of the Association of American Medical Colleges

Moniz T, Golafshani M, Gaspar CM, Adams NE, Haidet P, Sukhera J, Volpe RL, de Boer C, Lingard L.
PMID: 33830951
Acad Med. 2021 Apr 06; doi: 10.1097/ACM.0000000000004118. Epub 2021 Apr 06.

PURPOSE: Although focused reviews have characterized subsets of the literature on the arts and humanities in medical education, a large-scale overview of the field is needed to inform efforts to strengthen these approaches in medicine.METHOD: The authors conducted a...

Cite
Moniz T, Golafshani M, Gaspar CM, et al. How Are the Arts and Humanities Used in Medical Education? Results of a Scoping Review. Acad Med. 2021;doi: 10.1097/ACM.0000000000004118.
Moniz, T., Golafshani, M., Gaspar, C. M., Adams, N. E., Haidet, P., Sukhera, J., Volpe, R. L., de Boer, C., & Lingard, L. (2021). How Are the Arts and Humanities Used in Medical Education? Results of a Scoping Review. Academic medicine : journal of the Association of American Medical Colleges, . https://doi.org/10.1097/ACM.0000000000004118
Moniz, Tracy, et al. "How Are the Arts and Humanities Used in Medical Education? Results of a Scoping Review." Academic medicine : journal of the Association of American Medical Colleges vol. (2021). doi: https://doi.org/10.1097/ACM.0000000000004118
Moniz T, Golafshani M, Gaspar CM, Adams NE, Haidet P, Sukhera J, Volpe RL, de Boer C, Lingard L. How Are the Arts and Humanities Used in Medical Education? Results of a Scoping Review. Acad Med. 2021 Apr 06; doi: 10.1097/ACM.0000000000004118. Epub 2021 Apr 06. PMID: 33830951.
Copy Download .nbib Format: NLM
The Reply.

The American journal of medicine

Shapiro DE, Duquette C, Abbott LM, Babineau T, Pearl A, Haidet P.
PMID: 32867947
Am J Med. 2020 Sep;133(9):e534. doi: 10.1016/j.amjmed.2020.04.014.

No abstract available.

Cite
Shapiro DE, Duquette C, Abbott LM, et al. The Reply. Am J Med. 2020;133(9):e534doi: 10.1016/j.amjmed.2020.04.014.
Shapiro, D. E., Duquette, C., Abbott, L. M., Babineau, T., Pearl, A., & Haidet, P. (2020). The Reply. The American journal of medicine, 133(9), e534. https://doi.org/10.1016/j.amjmed.2020.04.014
Shapiro, Daniel E, et al. "The Reply." The American journal of medicine vol. 133,9 (2020): e534. doi: https://doi.org/10.1016/j.amjmed.2020.04.014
Shapiro DE, Duquette C, Abbott LM, Babineau T, Pearl A, Haidet P. The Reply. Am J Med. 2020 Sep;133(9):e534. doi: 10.1016/j.amjmed.2020.04.014. PMID: 32867947.
Copy Download .nbib Format: NLM
Multi-Sensor Spectral Imaging of Geological Samples: A Data Fusion Approach Using Spatio-Spectral Feature Extraction.

Sensors (Basel, Switzerland)

Lorenz S, Seidel P, Ghamisi P, Zimmermann R, Tusa L, Khodadadzadeh M, Contreras IC, Gloaguen R.
PMID: 31234309
Sensors (Basel). 2019 Jun 21;19(12). doi: 10.3390/s19122787.

Rapid, efficient and reproducible drillcore logging is fundamental in mineral exploration. Drillcore mapping has evolved rapidly in the recent decade, especially with the advances in hyperspectral spectral imaging. A wide range of imaging sensors is now available, providing rapidly...

Cite
Lorenz S, Seidel P, Ghamisi P, et al. Multi-Sensor Spectral Imaging of Geological Samples: A Data Fusion Approach Using Spatio-Spectral Feature Extraction. Sensors (Basel). 2019;19(12)doi: 10.3390/s19122787.
Lorenz, S., Seidel, P., Ghamisi, P., Zimmermann, R., Tusa, L., Khodadadzadeh, M., Contreras, I. C., & Gloaguen, R. (2019). Multi-Sensor Spectral Imaging of Geological Samples: A Data Fusion Approach Using Spatio-Spectral Feature Extraction. Sensors (Basel, Switzerland), 19(12), . https://doi.org/10.3390/s19122787
Lorenz, Sandra, et al. "Multi-Sensor Spectral Imaging of Geological Samples: A Data Fusion Approach Using Spatio-Spectral Feature Extraction." Sensors (Basel, Switzerland) vol. 19,12 (2019). doi: https://doi.org/10.3390/s19122787
Lorenz S, Seidel P, Ghamisi P, Zimmermann R, Tusa L, Khodadadzadeh M, Contreras IC, Gloaguen R. Multi-Sensor Spectral Imaging of Geological Samples: A Data Fusion Approach Using Spatio-Spectral Feature Extraction. Sensors (Basel). 2019 Jun 21;19(12). doi: 10.3390/s19122787. PMID: 31234309; PMCID: PMC6631011.
Copy Download .nbib Format: NLM
Therapeutic Effects of Inhibition of Sphingosine-1-Phosphate Signaling in HIF-2α Inhibitor-Resistant Clear Cell Renal Cell Carcinoma.

Cancers

Hoefflin R, Harlander S, Abhari BA, Peighambari A, Adlesic M, Seidel P, Zodel K, Haug S, Göcmen B, Li Y, Lahrmann B, Grabe N, Heide D, Boerries M, Köttgen A, Heikenwalder M, Frew IJ.
PMID: 34638286
Cancers (Basel). 2021 Sep 25;13(19). doi: 10.3390/cancers13194801.

Specific inhibitors of HIF-2α have recently been approved for the treatment of ccRCC in VHL disease patients and have shown encouraging results in clinical trials for metastatic sporadic ccRCC. However, not all patients respond to therapy and pre-clinical and...

Cite
Hoefflin R, Harlander S, Abhari BA, et al. Therapeutic Effects of Inhibition of Sphingosine-1-Phosphate Signaling in HIF-2α Inhibitor-Resistant Clear Cell Renal Cell Carcinoma. Cancers (Basel). 2021;13(19)doi: 10.3390/cancers13194801.
Hoefflin, R., Harlander, S., Abhari, B. A., Peighambari, A., Adlesic, M., Seidel, P., Zodel, K., Haug, S., Göcmen, B., Li, Y., Lahrmann, B., Grabe, N., Heide, D., Boerries, M., Köttgen, A., Heikenwalder, M., & Frew, I. J. (2021). Therapeutic Effects of Inhibition of Sphingosine-1-Phosphate Signaling in HIF-2α Inhibitor-Resistant Clear Cell Renal Cell Carcinoma. Cancers, 13(19), . https://doi.org/10.3390/cancers13194801
Hoefflin, Rouven, et al. "Therapeutic Effects of Inhibition of Sphingosine-1-Phosphate Signaling in HIF-2α Inhibitor-Resistant Clear Cell Renal Cell Carcinoma." Cancers vol. 13,19 (2021). doi: https://doi.org/10.3390/cancers13194801
Hoefflin R, Harlander S, Abhari BA, Peighambari A, Adlesic M, Seidel P, Zodel K, Haug S, Göcmen B, Li Y, Lahrmann B, Grabe N, Heide D, Boerries M, Köttgen A, Heikenwalder M, Frew IJ. Therapeutic Effects of Inhibition of Sphingosine-1-Phosphate Signaling in HIF-2α Inhibitor-Resistant Clear Cell Renal Cell Carcinoma. Cancers (Basel). 2021 Sep 25;13(19). doi: 10.3390/cancers13194801. PMID: 34638286; PMCID: PMC8508537.
Copy Download .nbib Format: NLM
Showing 25 to 36 of 200 entries