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Showing 733 to 744 of 2004 entries
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Significant changes in endogenous retinal gene expression assessed 1 year after a single intraocular injection of AAV-CNTF or AAV-BDNF.

Molecular therapy. Methods & clinical development

LeVaillant CJ, Sharma A, Muhling J, Wheeler LP, Cozens GS, Hellström M, Rodger J, Harvey AR.
PMID: 27933306
Mol Ther Methods Clin Dev. 2016 Dec 07;3:16078. doi: 10.1038/mtm.2016.78. eCollection 2016.

Use of viral vectors to deliver therapeutic genes to the central nervous system holds promise for the treatment of neurodegenerative diseases and neurotrauma. Adeno-associated viral (AAV) vectors encoding brain-derived neurotrophic factor (BDNF) or ciliary derived neurotrophic factor (CNTF) promote...

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LeVaillant CJ, Sharma A, Muhling J, et al. Significant changes in endogenous retinal gene expression assessed 1 year after a single intraocular injection of AAV-CNTF or AAV-BDNF. Mol Ther Methods Clin Dev. 2016;3:16078doi: 10.1038/mtm.2016.78.
LeVaillant, C. J., Sharma, A., Muhling, J., Wheeler, L. P., Cozens, G. S., Hellström, M., Rodger, J., & Harvey, A. R. (2016). Significant changes in endogenous retinal gene expression assessed 1 year after a single intraocular injection of AAV-CNTF or AAV-BDNF. Molecular therapy. Methods & clinical development, 316078. https://doi.org/10.1038/mtm.2016.78
LeVaillant, Chrisna J, et al. "Significant changes in endogenous retinal gene expression assessed 1 year after a single intraocular injection of AAV-CNTF or AAV-BDNF." Molecular therapy. Methods & clinical development vol. 3 (2016): 16078. doi: https://doi.org/10.1038/mtm.2016.78
LeVaillant CJ, Sharma A, Muhling J, Wheeler LP, Cozens GS, Hellström M, Rodger J, Harvey AR. Significant changes in endogenous retinal gene expression assessed 1 year after a single intraocular injection of AAV-CNTF or AAV-BDNF. Mol Ther Methods Clin Dev. 2016 Dec 07;3:16078. doi: 10.1038/mtm.2016.78. eCollection 2016. PMID: 27933306; PMCID: PMC5142514.
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Perceived discrimination and mental health among African American and Caribbean Black adolescents: ethnic differences in processes and effects.

Ethnicity & health

Smith NC, Nicholson HL.
PMID: 32977736
Ethn Health. 2020 Sep 25;1-18. doi: 10.1080/13557858.2020.1814998. Epub 2020 Sep 25.

No abstract available.

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Smith NC, Nicholson HL. Perceived discrimination and mental health among African American and Caribbean Black adolescents: ethnic differences in processes and effects. Ethn Health. 2020;1-18doi: 10.1080/13557858.2020.1814998.
Smith, N. C., & Nicholson, H. L. (2020). Perceived discrimination and mental health among African American and Caribbean Black adolescents: ethnic differences in processes and effects. Ethnicity & health, 1-18. https://doi.org/10.1080/13557858.2020.1814998
Smith, Nicholas C, and Nicholson, Harvey L. "Perceived discrimination and mental health among African American and Caribbean Black adolescents: ethnic differences in processes and effects." Ethnicity & health vol. (2020): 1-18. doi: https://doi.org/10.1080/13557858.2020.1814998
Smith NC, Nicholson HL. Perceived discrimination and mental health among African American and Caribbean Black adolescents: ethnic differences in processes and effects. Ethn Health. 2020 Sep 25;1-18. doi: 10.1080/13557858.2020.1814998. Epub 2020 Sep 25. PMID: 32977736.
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Critical decisions in metaproteomics: achieving high confidence protein annotations in a sea of unknowns.

The ISME journal

Timmins-Schiffman E, May DH, Mikan M, Riffle M, Frazar C, Harvey HR, Noble WS, Nunn BL.
PMID: 27824341
ISME J. 2017 Feb;11(2):309-314. doi: 10.1038/ismej.2016.132. Epub 2016 Nov 08.

No abstract available.

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Timmins-Schiffman E, May DH, Mikan M, et al. Critical decisions in metaproteomics: achieving high confidence protein annotations in a sea of unknowns. ISME J. 2016;11(2):309-314doi: 10.1038/ismej.2016.132.
Timmins-Schiffman, E., May, D. H., Mikan, M., Riffle, M., Frazar, C., Harvey, H. R., Noble, W. S., & Nunn, B. L. (2017). Critical decisions in metaproteomics: achieving high confidence protein annotations in a sea of unknowns. The ISME journal, 11(2), 309-314. https://doi.org/10.1038/ismej.2016.132
Timmins-Schiffman, Emma, et al. "Critical decisions in metaproteomics: achieving high confidence protein annotations in a sea of unknowns." The ISME journal vol. 11,2 (2017): 309-314. doi: https://doi.org/10.1038/ismej.2016.132
Timmins-Schiffman E, May DH, Mikan M, Riffle M, Frazar C, Harvey HR, Noble WS, Nunn BL. Critical decisions in metaproteomics: achieving high confidence protein annotations in a sea of unknowns. ISME J. 2017 Feb;11(2):309-314. doi: 10.1038/ismej.2016.132. Epub 2016 Nov 08. PMID: 27824341; PMCID: PMC5270573.
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Whole genome sequencing in transposition of the great arteries and associations with clinically relevant heart, brain and laterality genes.

American heart journal

Blue GM, Mekel M, Das D, Troup M, Rath E, Ip E, Gudkov M, Perumal G, Harvey RP, Sholler GF, Gecz J, Kirk EP, Liu J, Giannoulatou E, Hong H, Dunwoodie SL, Winlaw DS.
PMID: 34670123
Am Heart J. 2021 Oct 17;244:1-13. doi: 10.1016/j.ahj.2021.10.185. Epub 2021 Oct 17.

BACKGROUND: The most common cyanotic congenital heart disease (CHD) requiring management as a neonate is transposition of great arteries (TGA). Clinically, up to 50% of TGA patients develop some form of neurodevelopmental disability (NDD), thought to have a significant...

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Blue GM, Mekel M, Das D, et al. Whole genome sequencing in transposition of the great arteries and associations with clinically relevant heart, brain and laterality genes. Am Heart J. 2021;244:1-13doi: 10.1016/j.ahj.2021.10.185.
Blue, G. M., Mekel, M., Das, D., Troup, M., Rath, E., Ip, E., Gudkov, M., Perumal, G., Harvey, R. P., Sholler, G. F., Gecz, J., Kirk, E. P., Liu, J., Giannoulatou, E., Hong, H., Dunwoodie, S. L., & Winlaw, D. S. (2021). Whole genome sequencing in transposition of the great arteries and associations with clinically relevant heart, brain and laterality genes. American heart journal, 2441-13. https://doi.org/10.1016/j.ahj.2021.10.185
Blue, Gillian M, et al. "Whole genome sequencing in transposition of the great arteries and associations with clinically relevant heart, brain and laterality genes." American heart journal vol. 244 (2021): 1-13. doi: https://doi.org/10.1016/j.ahj.2021.10.185
Blue GM, Mekel M, Das D, Troup M, Rath E, Ip E, Gudkov M, Perumal G, Harvey RP, Sholler GF, Gecz J, Kirk EP, Liu J, Giannoulatou E, Hong H, Dunwoodie SL, Winlaw DS. Whole genome sequencing in transposition of the great arteries and associations with clinically relevant heart, brain and laterality genes. Am Heart J. 2021 Oct 17;244:1-13. doi: 10.1016/j.ahj.2021.10.185. Epub 2021 Oct 17. PMID: 34670123.
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Understanding the impact of professional motivation on the workforce crisis in medicine: a rapid review.

BJGP open

Andah E, Essang B, Friend C, Greenley S, Harvey K, Spears M, Reeve J.
PMID: 33653705
BJGP Open. 2021 Apr 26;5(2). doi: 10.3399/BJGPO.2021.0005. Print 2021 Apr.

BACKGROUND: The NHS is facing a workforce crisis. Responses to date have focused on improving recruitment of staff, but less attention has been paid to retention.AIM: To conduct a rapid review using Rosabeth Moss Kanter's three Ms model of...

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Andah E, Essang B, Friend C, et al. Understanding the impact of professional motivation on the workforce crisis in medicine: a rapid review. BJGP Open. 2021;5(2)doi: 10.3399/BJGPO.2021.0005.
Andah, E., Essang, B., Friend, C., Greenley, S., Harvey, K., Spears, M., & Reeve, J. (2021). Understanding the impact of professional motivation on the workforce crisis in medicine: a rapid review. BJGP open, 5(2), . https://doi.org/10.3399/BJGPO.2021.0005
Andah, Efioanwan, et al. "Understanding the impact of professional motivation on the workforce crisis in medicine: a rapid review." BJGP open vol. 5,2 (2021). doi: https://doi.org/10.3399/BJGPO.2021.0005
Andah E, Essang B, Friend C, Greenley S, Harvey K, Spears M, Reeve J. Understanding the impact of professional motivation on the workforce crisis in medicine: a rapid review. BJGP Open. 2021 Apr 26;5(2). doi: 10.3399/BJGPO.2021.0005. Print 2021 Apr. PMID: 33653705; PMCID: PMC8170605.
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Presence of ethanol-sensitive and ethanol-insensitive glycine receptors in the ventral tegmental area and prefrontal cortex in mice.

British journal of pharmacology

Araya A, Gallegos S, Viveros R, San Martin L, Muñoz B, Harvey RJ, Zeilhofer HU, Aguayo LG.
PMID: 34378188
Br J Pharmacol. 2021 Dec;178(23):4691-4707. doi: 10.1111/bph.15649. Epub 2021 Sep 17.

BACKGROUND AND PURPOSE: Glycine receptors composed of α1 and β subunits are primarily found in the spinal cord and brainstem and are potentiated by ethanol (10-100 mM). However, much less is known about the presence, composition and ethanol sensitivity...

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Araya A, Gallegos S, Viveros R, et al. Presence of ethanol-sensitive and ethanol-insensitive glycine receptors in the ventral tegmental area and prefrontal cortex in mice. Br J Pharmacol. 2021;178(23):4691-4707doi: 10.1111/bph.15649.
Araya, A., Gallegos, S., Viveros, R., San Martin, L., Muñoz, B., Harvey, R. J., Zeilhofer, H. U., & Aguayo, L. G. (2021). Presence of ethanol-sensitive and ethanol-insensitive glycine receptors in the ventral tegmental area and prefrontal cortex in mice. British journal of pharmacology, 178(23), 4691-4707. https://doi.org/10.1111/bph.15649
Araya, Anibal, et al. "Presence of ethanol-sensitive and ethanol-insensitive glycine receptors in the ventral tegmental area and prefrontal cortex in mice." British journal of pharmacology vol. 178,23 (2021): 4691-4707. doi: https://doi.org/10.1111/bph.15649
Araya A, Gallegos S, Viveros R, San Martin L, Muñoz B, Harvey RJ, Zeilhofer HU, Aguayo LG. Presence of ethanol-sensitive and ethanol-insensitive glycine receptors in the ventral tegmental area and prefrontal cortex in mice. Br J Pharmacol. 2021 Dec;178(23):4691-4707. doi: 10.1111/bph.15649. Epub 2021 Sep 17. PMID: 34378188.
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Early Use of High-Dose Glucocorticoid for the Management of irAE Is Associated with Poorer Survival in Patients with Advanced Melanoma Treated with Anti-PD-1 Monotherapy.

Clinical cancer research : an official journal of the American Association for Cancer Research

Bai X, Hu J, Betof Warner A, Quach HT, Cann CG, Zhang MZ, Si L, Tang B, Cui C, Yang X, Wei X, Pallan L, Harvey C, Manos MP, Ouyang O, Kim MS, Kasumova G, Cohen JV, Lawrence DP, Freedman C, Fadden RM, Rubin KM, Sharova T, Frederick DT, Flaherty KT, Rahma OE, Long GV, Menzies AM, Guo J, Shoushtari AN, Johnson DB, Sullivan RJ, Boland GM.
PMID: 34376536
Clin Cancer Res. 2021 Nov 01;27(21):5993-6000. doi: 10.1158/1078-0432.CCR-21-1283. Epub 2021 Aug 10.

PURPOSE: Programmed cell death receptor-1 (PD-1) inhibitors are frontline therapy in advanced melanoma. Severe immune-related adverse effects (irAEs) often require immunosuppressive treatment with glucocorticoids (GCCs), but GCC use and its correlation with patient survival outcomes during anti-PD-1 monotherapy remains...

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Bai X, Hu J, Betof Warner A, et al. Early Use of High-Dose Glucocorticoid for the Management of irAE Is Associated with Poorer Survival in Patients with Advanced Melanoma Treated with Anti-PD-1 Monotherapy. Clin Cancer Res. 2021;27(21):5993-6000doi: 10.1158/1078-0432.CCR-21-1283.
Bai, X., Hu, J., Betof Warner, A., Quach, H. T., Cann, C. G., Zhang, M. Z., Si, L., Tang, B., Cui, C., Yang, X., Wei, X., Pallan, L., Harvey, C., Manos, M. P., Ouyang, O., Kim, M. S., Kasumova, G., Cohen, J. V., Lawrence, D. P., Freedman, C., Fadden, R. M., Rubin, K. M., Sharova, T., Frederick, D. T., Flaherty, K. T., Rahma, O. E., Long, G. V., Menzies, A. M., Guo, J., Shoushtari, A. N., Johnson, D. B., Sullivan, R. J., & Boland, G. M. (2021). Early Use of High-Dose Glucocorticoid for the Management of irAE Is Associated with Poorer Survival in Patients with Advanced Melanoma Treated with Anti-PD-1 Monotherapy. Clinical cancer research : an official journal of the American Association for Cancer Research, 27(21), 5993-6000. https://doi.org/10.1158/1078-0432.CCR-21-1283
Bai, Xue, et al. "Early Use of High-Dose Glucocorticoid for the Management of irAE Is Associated with Poorer Survival in Patients with Advanced Melanoma Treated with Anti-PD-1 Monotherapy." Clinical cancer research : an official journal of the American Association for Cancer Research vol. 27,21 (2021): 5993-6000. doi: https://doi.org/10.1158/1078-0432.CCR-21-1283
Bai X, Hu J, Betof Warner A, Quach HT, Cann CG, Zhang MZ, Si L, Tang B, Cui C, Yang X, Wei X, Pallan L, Harvey C, Manos MP, Ouyang O, Kim MS, Kasumova G, Cohen JV, Lawrence DP, Freedman C, Fadden RM, Rubin KM, Sharova T, Frederick DT, Flaherty KT, Rahma OE, Long GV, Menzies AM, Guo J, Shoushtari AN, Johnson DB, Sullivan RJ, Boland GM. Early Use of High-Dose Glucocorticoid for the Management of irAE Is Associated with Poorer Survival in Patients with Advanced Melanoma Treated with Anti-PD-1 Monotherapy. Clin Cancer Res. 2021 Nov 01;27(21):5993-6000. doi: 10.1158/1078-0432.CCR-21-1283. Epub 2021 Aug 10. PMID: 34376536.
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The Postural Tachycardia Syndrome (PoTS) Bladder-Urodynamic Findings.

Urology

Faure Walker N, Gall R, Gall N, Feuer J, Harvey H, Taylor C.
PMID: 33676954
Urology. 2021 Jul;153:107-112. doi: 10.1016/j.urology.2021.02.028. Epub 2021 Mar 04.

OBJECTIVE: To evaluate the urodynamics (UDS) of patients with postural tachycardia syndrome (PoTS).METHODS: Patients with a confirmed diagnosis of PoTS referred by the department of neuro-cardiology to the neuro-urology were identified and their UDS were retrospectively reviewed.RESULTS: In total,...

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Faure Walker N, Gall R, Gall N, et al. The Postural Tachycardia Syndrome (PoTS) Bladder-Urodynamic Findings. Urology. 2021;153:107-112doi: 10.1016/j.urology.2021.02.028.
Faure Walker, N., Gall, R., Gall, N., Feuer, J., Harvey, H., & Taylor, C. (2021). The Postural Tachycardia Syndrome (PoTS) Bladder-Urodynamic Findings. Urology, 153107-112. https://doi.org/10.1016/j.urology.2021.02.028
Faure Walker, Nicholas, et al. "The Postural Tachycardia Syndrome (PoTS) Bladder-Urodynamic Findings." Urology vol. 153 (2021): 107-112. doi: https://doi.org/10.1016/j.urology.2021.02.028
Faure Walker N, Gall R, Gall N, Feuer J, Harvey H, Taylor C. The Postural Tachycardia Syndrome (PoTS) Bladder-Urodynamic Findings. Urology. 2021 Jul;153:107-112. doi: 10.1016/j.urology.2021.02.028. Epub 2021 Mar 04. PMID: 33676954.
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Correction: Breadth and function of antibody response to acute SARS-CoV-2 infection in humans.

PLoS pathogens

Huang KA, Tan TK, Chen TH, Huang CG, Harvey R, Hussain S, Chen CP, Harding A, Gilbert-Jaramillo J, Liu X, Knight M, Schimanski L, Shih SR, Lin YC, Cheng CY, Cheng SH, Huang YC, Lin TY, Jan JT, Ma C, James W, Daniels RS, McCauley JW, Rijal P, Townsend AR.
PMID: 34890427
PLoS Pathog. 2021 Dec 10;17(12):e1010148. doi: 10.1371/journal.ppat.1010148. eCollection 2021 Dec.

[This corrects the article DOI: 10.1371/journal.ppat.1009352.].

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Huang KA, Tan TK, Chen TH, et al. Correction: Breadth and function of antibody response to acute SARS-CoV-2 infection in humans. PLoS Pathog. 2021;17(12):e1010148doi: 10.1371/journal.ppat.1010148.
Huang, K. A., Tan, T. K., Chen, T. H., Huang, C. G., Harvey, R., Hussain, S., Chen, C. P., Harding, A., Gilbert-Jaramillo, J., Liu, X., Knight, M., Schimanski, L., Shih, S. R., Lin, Y. C., Cheng, C. Y., Cheng, S. H., Huang, Y. C., Lin, T. Y., Jan, J. T., Ma, C., James, W., Daniels, R. S., McCauley, J. W., Rijal, P., & Townsend, A. R. (2021). Correction: Breadth and function of antibody response to acute SARS-CoV-2 infection in humans. PLoS pathogens, 17(12), e1010148. https://doi.org/10.1371/journal.ppat.1010148
Huang, Kuan-Ying A, et al. "Correction: Breadth and function of antibody response to acute SARS-CoV-2 infection in humans." PLoS pathogens vol. 17,12 (2021): e1010148. doi: https://doi.org/10.1371/journal.ppat.1010148
Huang KA, Tan TK, Chen TH, Huang CG, Harvey R, Hussain S, Chen CP, Harding A, Gilbert-Jaramillo J, Liu X, Knight M, Schimanski L, Shih SR, Lin YC, Cheng CY, Cheng SH, Huang YC, Lin TY, Jan JT, Ma C, James W, Daniels RS, McCauley JW, Rijal P, Townsend AR. Correction: Breadth and function of antibody response to acute SARS-CoV-2 infection in humans. PLoS Pathog. 2021 Dec 10;17(12):e1010148. doi: 10.1371/journal.ppat.1010148. eCollection 2021 Dec. PMID: 34890427; PMCID: PMC8664163.
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Compartmentalized cAMP signaling in cardiac ventricular myocytes.

Cellular signalling

Agarwal SR, Sherpa RT, Moshal KS, Harvey RD.
PMID: 34687901
Cell Signal. 2022 Jan;89:110172. doi: 10.1016/j.cellsig.2021.110172. Epub 2021 Oct 20.

Activation of different receptors that act by generating the common second messenger cyclic adenosine monophosphate (cAMP) can elicit distinct functional responses in cardiac myocytes. Selectively sequestering cAMP activity to discrete intracellular microdomains is considered essential for generating receptor-specific responses....

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Agarwal SR, Sherpa RT, Moshal KS, et al. Compartmentalized cAMP signaling in cardiac ventricular myocytes. Cell Signal. 2021;89:110172doi: 10.1016/j.cellsig.2021.110172.
Agarwal, S. R., Sherpa, R. T., Moshal, K. S., & Harvey, R. D. (2022). Compartmentalized cAMP signaling in cardiac ventricular myocytes. Cellular signalling, 89110172. https://doi.org/10.1016/j.cellsig.2021.110172
Agarwal, Shailesh R, et al. "Compartmentalized cAMP signaling in cardiac ventricular myocytes." Cellular signalling vol. 89 (2022): 110172. doi: https://doi.org/10.1016/j.cellsig.2021.110172
Agarwal SR, Sherpa RT, Moshal KS, Harvey RD. Compartmentalized cAMP signaling in cardiac ventricular myocytes. Cell Signal. 2022 Jan;89:110172. doi: 10.1016/j.cellsig.2021.110172. Epub 2021 Oct 20. PMID: 34687901; PMCID: PMC8602782.
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Rapalink-1 Increased Infarct Size in Early Cerebral Ischemia-Reperfusion With Increased Blood-Brain Barrier Disruption.

Frontiers in physiology

Chi OZ, Liu X, Cofano S, Patel N, Jacinto E, Weiss HR.
PMID: 34354602
Front Physiol. 2021 Jul 20;12:706528. doi: 10.3389/fphys.2021.706528. eCollection 2021.

It has been reported that the mechanistic target of rapamycin (mTOR) pathway is involved in cerebral ischemia-reperfusion injury. One of the important pathological changes during reperfusion after cerebral ischemia is disruption of blood-brain barrier (BBB). Rapamycin, a first-generation mTOR...

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Chi OZ, Liu X, Cofano S, et al. Rapalink-1 Increased Infarct Size in Early Cerebral Ischemia-Reperfusion With Increased Blood-Brain Barrier Disruption. Front Physiol. 2021;12:706528doi: 10.3389/fphys.2021.706528.
Chi, O. Z., Liu, X., Cofano, S., Patel, N., Jacinto, E., & Weiss, H. R. (2021). Rapalink-1 Increased Infarct Size in Early Cerebral Ischemia-Reperfusion With Increased Blood-Brain Barrier Disruption. Frontiers in physiology, 12706528. https://doi.org/10.3389/fphys.2021.706528
Chi, Oak Z, et al. "Rapalink-1 Increased Infarct Size in Early Cerebral Ischemia-Reperfusion With Increased Blood-Brain Barrier Disruption." Frontiers in physiology vol. 12 (2021): 706528. doi: https://doi.org/10.3389/fphys.2021.706528
Chi OZ, Liu X, Cofano S, Patel N, Jacinto E, Weiss HR. Rapalink-1 Increased Infarct Size in Early Cerebral Ischemia-Reperfusion With Increased Blood-Brain Barrier Disruption. Front Physiol. 2021 Jul 20;12:706528. doi: 10.3389/fphys.2021.706528. eCollection 2021. PMID: 34354602; PMCID: PMC8329705.
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Peer Review Guidance for Evaluating the Narrative Review: Lessons Applied From the Systematic Review.

Journal of cardiothoracic and vascular anesthesia

Harvey R, Williams TM, Hernandez-Morgan M, Fischer MA, Neelankavil J.
PMID: 34903460
J Cardiothorac Vasc Anesth. 2021 Nov 14; doi: 10.1053/j.jvca.2021.11.020. Epub 2021 Nov 14.

No abstract available.

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Harvey R, Williams TM, Hernandez-Morgan M, et al. Peer Review Guidance for Evaluating the Narrative Review: Lessons Applied From the Systematic Review. J Cardiothorac Vasc Anesth. 2021;doi: 10.1053/j.jvca.2021.11.020.
Harvey, R., Williams, T. M., Hernandez-Morgan, M., Fischer, M. A., & Neelankavil, J. (2021). Peer Review Guidance for Evaluating the Narrative Review: Lessons Applied From the Systematic Review. Journal of cardiothoracic and vascular anesthesia, . https://doi.org/10.1053/j.jvca.2021.11.020
Harvey, Reed, et al. "Peer Review Guidance for Evaluating the Narrative Review: Lessons Applied From the Systematic Review." Journal of cardiothoracic and vascular anesthesia vol. (2021). doi: https://doi.org/10.1053/j.jvca.2021.11.020
Harvey R, Williams TM, Hernandez-Morgan M, Fischer MA, Neelankavil J. Peer Review Guidance for Evaluating the Narrative Review: Lessons Applied From the Systematic Review. J Cardiothorac Vasc Anesth. 2021 Nov 14; doi: 10.1053/j.jvca.2021.11.020. Epub 2021 Nov 14. PMID: 34903460.
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Showing 733 to 744 of 2004 entries