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Showing 1357 to 1368 of 3124 entries
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Complete genome for .

Microbial genomics

Bossé JT, Li Y, Cohen LM, Stegger M, Angen Ø, Lacouture S, Gottschalk M, Lei L, Koene M, Kuhnert P, Bandara AB, Inzana TJ, Holden MTG, Harris D, Oshota O, Maskell DJ, Tucker AW, Wren BW, Rycroft AN, Langford PR, On Behalf Of The BRaDP T Consortium.
PMID: 34818145
Microb Genom. 2021 Nov;7(11). doi: 10.1099/mgen.0.000687.

We report here the complete genome sequence of the widely studied

Mutational Signatures of Replication Timing and Epigenetic Modification Persist through the Global Divergence of Mutation Spectra across the Great Ape Phylogeny.

Genome biology and evolution

Goldberg ME, Harris K.
PMID: 33983415
Genome Biol Evol. 2022 Jan 04;14(1). doi: 10.1093/gbe/evab104.

Great ape clades exhibit variation in the relative mutation rates of different three-base-pair genomic motifs, with closely related species having more similar mutation spectra than distantly related species. This pattern cannot be explained by classical demographic or selective forces,...

Multimodal Mapping of the Tumor and Peripheral Blood Immune Landscape in Human Pancreatic Cancer.

Nature cancer

Steele NG, Carpenter ES, Kemp SB, Sirihorachai V, The S, Delrosario L, Lazarus J, Amir ED, Gunchick V, Espinoza C, Bell S, Harris L, Lima F, Irizarry-Negron V, Paglia D, Macchia J, Chu AKY, Schofield H, Wamsteker EJ, Kwon R, Schulman A, Prabhu A, Law R, Sondhi A, Yu J, Patel A, Donahue K, Nathan H, Cho C, Anderson MA, Sahai V, Lyssiotis CA, Zou W, Allen BL, Rao A, Crawford HC, Bednar F, Frankel TL, Pasca di Magliano M.
PMID: 34296197
Nat Cancer. 2020 Nov;1(11):1097-1112. doi: 10.1038/s43018-020-00121-4. Epub 2020 Oct 26.

Pancreatic ductal adenocarcinoma (PDA) is characterized by an immune-suppressive tumor microenvironment that renders it largely refractory to immunotherapy. We implemented a multimodal analysis approach to elucidate the immune landscape in PDA. Using a combination of CyTOF, single-cell RNA sequencing,...

Primary orthostatic tremor and orthostatic tremor-plus in dogs: 60 cases (2003-2020).

Journal of veterinary internal medicine

Liatis T, Gutierrez-Quintana R, Mari L, Czopowicz M, Polidoro D, Bhatti SFM, Cozzi F, Tirrito F, Brocal J, José-López R, Kaczmarska A, Cappello R, Harris G, Alves L, Rusbridge C, Rossmeisl JH.
PMID: 34897811
J Vet Intern Med. 2021 Dec 12; doi: 10.1111/jvim.16328. Epub 2021 Dec 12.

BACKGROUND: Orthostatic tremor (OT) is a rare movement disorder characterized by high-frequency (>12 Hz) involuntary, rhythmic, sinusoidal movements affecting predominantly the limbs while standing.OBJECTIVE: To describe the signalment, presenting complaints, phenotype, diagnostic findings, treatment, and outcome of a large...

Past due: improving the naming of psychiatric disorders.

The lancet. Psychiatry

Cohen BM, Öngür D, Harris PQ.
PMID: 34998479
Lancet Psychiatry. 2022 Jan 06; doi: 10.1016/S2215-0366(21)00478-8. Epub 2022 Jan 06.

No abstract available.

Clinical outcomes following pharyngolaryngectomy reconstruction: a 20-year single centre study.

The Journal of laryngology and otology

Layton T, Thomas R, Harris C, Holmes S, Fraser L, Silva P, Winter SC.
PMID: 35000624
J Laryngol Otol. 2022 Jan 10;1-18. doi: 10.1017/S0022215122000019. Epub 2022 Jan 10.

No abstract available.

NRF2 activation inhibits valproic acid-induced neural tube defects in mice.

Neurotoxicology and teratology

Piorczynski TB, Lapehn S, Ringer KP, Allen SA, Johnson GA, Call K, Lucas SM, Harris C, Hansen JM.
PMID: 34737154
Neurotoxicol Teratol. 2021 Oct 29;89:107039. doi: 10.1016/j.ntt.2021.107039. Epub 2021 Oct 29.

Valproic acid (VPA) is a widely prescribed medication that has traditionally been used to treat epilepsy, yet embryonic exposure to VPA increases the risk of the fetus developing neural tube defects (NTDs). While the mechanism by which VPA causes...

Feasibility and Provisional Efficacy of Embedding High-Intensity Interval Training Into Physical Education Lessons: A Pilot Cluster-Randomized Controlled Trial.

Pediatric exercise science

Harris N, Warbrick I, Atkins D, Vandal A, Plank L, Lubans DR.
PMID: 34348226
Pediatr Exerc Sci. 2021 Aug 04;33(4):186-195. doi: 10.1123/pes.2020-0255.

PURPOSE: The aim of this study was to determine the feasibility of generalist school teachers delivering curriculum connected high-intensity interval training in a school's physical education class time.METHOD: Two schools volunteered to participate. A total of 84 students (11.9...

Benefiting the NHS through innovation: how to ensure international health partnerships are genuinely reciprocal.

BMJ global health

Issa H, Townsend W, Harris M.
PMID: 34853066
BMJ Glob Health. 2021 Nov;6. doi: 10.1136/bmjgh-2021-004936.

No abstract available.

Unexpected benefit of COVID-19 hospital restrictions: Reduction in patients isolating with multidrug resistant organisms after restrictions were lifted.

Infection, disease & health

Elliott TM, Hurst C, Doidge M, Hurst T, Harris PN, Gordon LG.
PMID: 34507923
Infect Dis Health. 2021 Aug 18; doi: 10.1016/j.idh.2021.08.001. Epub 2021 Aug 18.

BACKGROUND: During the COVID-19 pandemic, measures to prevent microorganism transmission were implemented across hospitals, including wearing compulsory surgical masks, minimising non-urgent procedures and restricting visitors. Previously, concerns have been raised that MRO-associated deaths could rise during a future pandemic...

An examination of active inference in autistic adults using immersive virtual reality.

Scientific reports

Arthur T, Harris D, Buckingham G, Brosnan M, Wilson M, Williams G, Vine S.
PMID: 34645899
Sci Rep. 2021 Oct 13;11(1):20377. doi: 10.1038/s41598-021-99864-y.

The integration of prior expectations, sensory information, and environmental volatility is proposed to be atypical in Autism Spectrum Disorder, yet few studies have tested these predictive processes in active movement tasks. To address this gap in the research, we...

A new automated method for high-throughput carbon and hydrogen isotope analysis of gaseous and dissolved methane at atmospheric concentrations.

Rapid communications in mass spectrometry : RCM

Smith AC, Welsh S, Atkinson H, Harris D, Leng MJ.
PMID: 33738862
Rapid Commun Mass Spectrom. 2021 Jun 30;35(11):e9086. doi: 10.1002/rcm.9086.

RATIONALE: The dual isotope ratio analysis, carbon (δMETHODS: Here we describe a new gas chromatography, pyrolysis/combustion, isotope ratio mass spectrometry (IRMS) system for the automated analysis of either dissolved or gaseous CHRESULTS: The system routinely achieves precision of

Showing 1357 to 1368 of 3124 entries