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A mobile angular scattering microscope for organelle size estimation.

The Review of scientific instruments

Cannaday AE, Hanna S, Hoelle J.
PMID: 34470384
Rev Sci Instrum. 2021 Aug 01;92(8):083702. doi: 10.1063/5.0054975.

Angular light scattering measurements have been used to determine the size parameters of spherical particles. By measuring the angular scattering from biological specimen, the average size of the cellular organelles can be estimated, which can be used to determine...

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Cannaday AE, Hanna S, Hoelle J. A mobile angular scattering microscope for organelle size estimation. Rev Sci Instrum. 2021;92(8):083702doi: 10.1063/5.0054975.
Cannaday, A. E., Hanna, S., & Hoelle, J. (2021). A mobile angular scattering microscope for organelle size estimation. The Review of scientific instruments, 92(8), 083702. https://doi.org/10.1063/5.0054975
Cannaday, Ashley E, et al. "A mobile angular scattering microscope for organelle size estimation." The Review of scientific instruments vol. 92,8 (2021): 083702. doi: https://doi.org/10.1063/5.0054975
Cannaday AE, Hanna S, Hoelle J. A mobile angular scattering microscope for organelle size estimation. Rev Sci Instrum. 2021 Aug 01;92(8):083702. doi: 10.1063/5.0054975. PMID: 34470384.
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Proteomic profiling of MIS-C patients indicates heterogeneity relating to interferon gamma dysregulation and vascular endothelial dysfunction.

Nature communications

Diorio C, Shraim R, Vella LA, Giles JR, Baxter AE, Oldridge DA, Canna SW, Henrickson SE, McNerney KO, Balamuth F, Burudpakdee C, Lee J, Leng T, Farrel A, Lambert MP, Sullivan KE, Wherry EJ, Teachey DT, Bassiri H, Behrens EM.
PMID: 34893640
Nat Commun. 2021 Dec 10;12(1):7222. doi: 10.1038/s41467-021-27544-6.

Multi-system Inflammatory Syndrome in Children (MIS-C) is a major complication of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection in pediatric patients. Weeks after an often mild or asymptomatic initial infection with SARS-CoV-2 children may present with a severe...

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Diorio C, Shraim R, Vella LA, et al. Proteomic profiling of MIS-C patients indicates heterogeneity relating to interferon gamma dysregulation and vascular endothelial dysfunction. Nat Commun. 2021;12(1):7222doi: 10.1038/s41467-021-27544-6.
Diorio, C., Shraim, R., Vella, L. A., Giles, J. R., Baxter, A. E., Oldridge, D. A., Canna, S. W., Henrickson, S. E., McNerney, K. O., Balamuth, F., Burudpakdee, C., Lee, J., Leng, T., Farrel, A., Lambert, M. P., Sullivan, K. E., Wherry, E. J., Teachey, D. T., Bassiri, H., & Behrens, E. M. (2021). Proteomic profiling of MIS-C patients indicates heterogeneity relating to interferon gamma dysregulation and vascular endothelial dysfunction. Nature communications, 12(1), 7222. https://doi.org/10.1038/s41467-021-27544-6
Diorio, Caroline, et al. "Proteomic profiling of MIS-C patients indicates heterogeneity relating to interferon gamma dysregulation and vascular endothelial dysfunction." Nature communications vol. 12,1 (2021): 7222. doi: https://doi.org/10.1038/s41467-021-27544-6
Diorio C, Shraim R, Vella LA, Giles JR, Baxter AE, Oldridge DA, Canna SW, Henrickson SE, McNerney KO, Balamuth F, Burudpakdee C, Lee J, Leng T, Farrel A, Lambert MP, Sullivan KE, Wherry EJ, Teachey DT, Bassiri H, Behrens EM. Proteomic profiling of MIS-C patients indicates heterogeneity relating to interferon gamma dysregulation and vascular endothelial dysfunction. Nat Commun. 2021 Dec 10;12(1):7222. doi: 10.1038/s41467-021-27544-6. PMID: 34893640.
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Constraints and performance trade-offs in Auger-suppressed HgCdTe focal plane arrays.

Applied optics

Vallone M, Goano M, Bertazzi F, Ghione G, Hanna S, Eich D, Sieck A, Figgemeier H.
PMID: 32543506
Appl Opt. 2020 Jun 10;59(17):E1-E8. doi: 10.1364/AO.385075.

Majority carrier depletion has been proposed as a method to suppress the dark current originating from quasi-neutral regions in HgCdTe infrared focal plane array detectors. However, a very low doping level is usually required for the absorber layer, a...

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Vallone M, Goano M, Bertazzi F, et al. Constraints and performance trade-offs in Auger-suppressed HgCdTe focal plane arrays. Appl Opt. 2020;59(17):E1-E8doi: 10.1364/AO.385075.
Vallone, M., Goano, M., Bertazzi, F., Ghione, G., Hanna, S., Eich, D., Sieck, A., & Figgemeier, H. (2020). Constraints and performance trade-offs in Auger-suppressed HgCdTe focal plane arrays. Applied optics, 59(17), E1-E8. https://doi.org/10.1364/AO.385075
Vallone, Marco, et al. "Constraints and performance trade-offs in Auger-suppressed HgCdTe focal plane arrays." Applied optics vol. 59,17 (2020): E1-E8. doi: https://doi.org/10.1364/AO.385075
Vallone M, Goano M, Bertazzi F, Ghione G, Hanna S, Eich D, Sieck A, Figgemeier H. Constraints and performance trade-offs in Auger-suppressed HgCdTe focal plane arrays. Appl Opt. 2020 Jun 10;59(17):E1-E8. doi: 10.1364/AO.385075. PMID: 32543506.
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Polymorphisms within Immune Regulatory Pathways Predict Cetuximab Efficacy and Survival in Metastatic Colorectal Cancer Patients.

Cancers

Volz NB, Hanna DL, Stintzing S, Zhang W, Yang D, Cao S, Ning Y, Matsusaka S, Sunakawa Y, Berger MD, Cremolini C, Loupakis F, Falcone A, Lenz HJ.
PMID: 33065994
Cancers (Basel). 2020 Oct 13;12(10). doi: 10.3390/cancers12102947.

Cetuximab, an IgG1 EGFR-directed antibody, promotes antibody-dependent cell-mediated cytotoxicity. We hypothesized that single-nucleotide polymorphisms (SNPs) in immune regulatory pathways may predict outcomes in patients with metastatic colorectal cancer treated with cetuximab-based regimens. A total of 924 patients were included:...

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Volz NB, Hanna DL, Stintzing S, et al. Polymorphisms within Immune Regulatory Pathways Predict Cetuximab Efficacy and Survival in Metastatic Colorectal Cancer Patients. Cancers (Basel). 2020;12(10)doi: 10.3390/cancers12102947.
Volz, N. B., Hanna, D. L., Stintzing, S., Zhang, W., Yang, D., Cao, S., Ning, Y., Matsusaka, S., Sunakawa, Y., Berger, M. D., Cremolini, C., Loupakis, F., Falcone, A., & Lenz, H. J. (2020). Polymorphisms within Immune Regulatory Pathways Predict Cetuximab Efficacy and Survival in Metastatic Colorectal Cancer Patients. Cancers, 12(10), . https://doi.org/10.3390/cancers12102947
Volz, Nico B, et al. "Polymorphisms within Immune Regulatory Pathways Predict Cetuximab Efficacy and Survival in Metastatic Colorectal Cancer Patients." Cancers vol. 12,10 (2020). doi: https://doi.org/10.3390/cancers12102947
Volz NB, Hanna DL, Stintzing S, Zhang W, Yang D, Cao S, Ning Y, Matsusaka S, Sunakawa Y, Berger MD, Cremolini C, Loupakis F, Falcone A, Lenz HJ. Polymorphisms within Immune Regulatory Pathways Predict Cetuximab Efficacy and Survival in Metastatic Colorectal Cancer Patients. Cancers (Basel). 2020 Oct 13;12(10). doi: 10.3390/cancers12102947. PMID: 33065994; PMCID: PMC7601940.
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Differential influence of antibiotic therapy and other medications on oncological outcomes of patients with non-small cell lung cancer treated with first-line pembrolizumab versus cytotoxic chemotherapy.

Journal for immunotherapy of cancer

Cortellini A, Di Maio M, Nigro O, Leonetti A, Cortinovis DL, Aerts JG, Guaitoli G, Barbieri F, Giusti R, Ferrara MG, Bria E, D'Argento E, Grossi F, Rijavec E, Guida A, Berardi R, Torniai M, Sforza V, Genova C, Mazzoni F, Garassino MC, De Toma A, Signorelli D, Gelibter A, Siringo M, Marchetti P, Macerelli M, Rastelli F, Chiari R, Rocco D, Della Gravara L, Inno A, Michele T, Grassadonia A, Di Marino P, Mansueto G, Zoratto F, Filetti M, Santini D, Citarella F, Russano M, Cantini L, Tuzi A, Bordi P, Minuti G, Landi L, Ricciardi S, Migliorino MR, Passiglia F, Bironzo P, Metro G, Adamo V, Russo A, Spinelli GP, Banna GL, Friedlaender A, Addeo A, Cannita K, Ficorella C, Porzio G, Pinato DJ.
PMID: 33827906
J Immunother Cancer. 2021 Apr;9(4). doi: 10.1136/jitc-2021-002421.

BACKGROUND: Some concomitant medications including antibiotics (ATB) have been reproducibly associated with worse survival following immune checkpoint inhibitors (ICIs) in unselected patients with non-small cell lung cancer (NSCLC) (according to programmed death-ligand 1 (PD-L1) expression and treatment line). Whether...

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Cortellini A, Di Maio M, Nigro O, et al. Differential influence of antibiotic therapy and other medications on oncological outcomes of patients with non-small cell lung cancer treated with first-line pembrolizumab versus cytotoxic chemotherapy. J Immunother Cancer. 2021;9(4)doi: 10.1136/jitc-2021-002421.
Cortellini, A., Di Maio, M., Nigro, O., Leonetti, A., Cortinovis, D. L., Aerts, J. G., Guaitoli, G., Barbieri, F., Giusti, R., Ferrara, M. G., Bria, E., D'Argento, E., Grossi, F., Rijavec, E., Guida, A., Berardi, R., Torniai, M., Sforza, V., Genova, C., Mazzoni, F., Garassino, M. C., De Toma, A., Signorelli, D., Gelibter, A., Siringo, M., Marchetti, P., Macerelli, M., Rastelli, F., Chiari, R., Rocco, D., Della Gravara, L., Inno, A., Michele, T., Grassadonia, A., Di Marino, P., Mansueto, G., Zoratto, F., Filetti, M., Santini, D., Citarella, F., Russano, M., Cantini, L., Tuzi, A., Bordi, P., Minuti, G., Landi, L., Ricciardi, S., Migliorino, M. R., Passiglia, F., Bironzo, P., Metro, G., Adamo, V., Russo, A., Spinelli, G. P., Banna, G. L., Friedlaender, A., Addeo, A., Cannita, K., Ficorella, C., Porzio, G., & Pinato, D. J. (2021). Differential influence of antibiotic therapy and other medications on oncological outcomes of patients with non-small cell lung cancer treated with first-line pembrolizumab versus cytotoxic chemotherapy. Journal for immunotherapy of cancer, 9(4), . https://doi.org/10.1136/jitc-2021-002421
Cortellini, Alessio, et al. "Differential influence of antibiotic therapy and other medications on oncological outcomes of patients with non-small cell lung cancer treated with first-line pembrolizumab versus cytotoxic chemotherapy." Journal for immunotherapy of cancer vol. 9,4 (2021). doi: https://doi.org/10.1136/jitc-2021-002421
Cortellini A, Di Maio M, Nigro O, Leonetti A, Cortinovis DL, Aerts JG, Guaitoli G, Barbieri F, Giusti R, Ferrara MG, Bria E, D'Argento E, Grossi F, Rijavec E, Guida A, Berardi R, Torniai M, Sforza V, Genova C, Mazzoni F, Garassino MC, De Toma A, Signorelli D, Gelibter A, Siringo M, Marchetti P, Macerelli M, Rastelli F, Chiari R, Rocco D, Della Gravara L, Inno A, Michele T, Grassadonia A, Di Marino P, Mansueto G, Zoratto F, Filetti M, Santini D, Citarella F, Russano M, Cantini L, Tuzi A, Bordi P, Minuti G, Landi L, Ricciardi S, Migliorino MR, Passiglia F, Bironzo P, Metro G, Adamo V, Russo A, Spinelli GP, Banna GL, Friedlaender A, Addeo A, Cannita K, Ficorella C, Porzio G, Pinato DJ. Differential influence of antibiotic therapy and other medications on oncological outcomes of patients with non-small cell lung cancer treated with first-line pembrolizumab versus cytotoxic chemotherapy. J Immunother Cancer. 2021 Apr;9(4). doi: 10.1136/jitc-2021-002421. PMID: 33827906; PMCID: PMC8031700.
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Effects of voluntary exercise on the expression of browning markers in visceral and subcutaneous fat tissue of normotensive and spontaneously hypertensive rats.

Pflugers Archiv : European journal of physiology

Karadedeli MS, Schreckenberg R, Kutsche HS, Schlüter KD.
PMID: 34893937
Pflugers Arch. 2022 Feb;474(2):205-215. doi: 10.1007/s00424-021-02629-9. Epub 2021 Dec 10.

High physical activity is important to optimize the function of adipose tissue. Dysfunctional adipose tissue contributes to the development of metabolic stress, chronic inflammation, and hypertension. To improve our current understanding of the interaction between physical exercise and adipose...

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Karadedeli MS, Schreckenberg R, Kutsche HS, et al. Effects of voluntary exercise on the expression of browning markers in visceral and subcutaneous fat tissue of normotensive and spontaneously hypertensive rats. Pflugers Arch. 2021;474(2):205-215doi: 10.1007/s00424-021-02629-9.
Karadedeli, M. S., Schreckenberg, R., Kutsche, H. S., & Schlüter, K. D. (2022). Effects of voluntary exercise on the expression of browning markers in visceral and subcutaneous fat tissue of normotensive and spontaneously hypertensive rats. Pflugers Archiv : European journal of physiology, 474(2), 205-215. https://doi.org/10.1007/s00424-021-02629-9
Karadedeli, Meryem Sevval, et al. "Effects of voluntary exercise on the expression of browning markers in visceral and subcutaneous fat tissue of normotensive and spontaneously hypertensive rats." Pflugers Archiv : European journal of physiology vol. 474,2 (2022): 205-215. doi: https://doi.org/10.1007/s00424-021-02629-9
Karadedeli MS, Schreckenberg R, Kutsche HS, Schlüter KD. Effects of voluntary exercise on the expression of browning markers in visceral and subcutaneous fat tissue of normotensive and spontaneously hypertensive rats. Pflugers Arch. 2022 Feb;474(2):205-215. doi: 10.1007/s00424-021-02629-9. Epub 2021 Dec 10. PMID: 34893937.
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Transport and dispersion of tracers simulating COVID-19 aerosols in passenger aircraft.

Indoor air

Hanna S.
PMID: 34921460
Indoor Air. 2021 Dec 17; doi: 10.1111/ina.12974. Epub 2021 Dec 17.

Many laboratory experiments and model development activities have been underway to better estimate the risk of a person indoors becoming infected with COVID-19. The current paper focusses on the near-field (distances 

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Hanna S. Transport and dispersion of tracers simulating COVID-19 aerosols in passenger aircraft. Indoor Air. 2021;doi: 10.1111/ina.12974.
Hanna, S. (2021). Transport and dispersion of tracers simulating COVID-19 aerosols in passenger aircraft. Indoor air, . https://doi.org/10.1111/ina.12974
Hanna, Steven. "Transport and dispersion of tracers simulating COVID-19 aerosols in passenger aircraft." Indoor air vol. (2021). doi: https://doi.org/10.1111/ina.12974
Hanna S. Transport and dispersion of tracers simulating COVID-19 aerosols in passenger aircraft. Indoor Air. 2021 Dec 17; doi: 10.1111/ina.12974. Epub 2021 Dec 17. PMID: 34921460.
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A historical overview of the activation and porosity of metal-organic frameworks.

Chemical Society reviews

Zhang X, Chen Z, Liu X, Hanna SL, Wang X, Taheri-Ledari R, Maleki A, Li P, Farha OK.
PMID: 32955065
Chem Soc Rev. 2020 Oct 19;49(20):7406-7427. doi: 10.1039/d0cs00997k.

Since the first reports of metal-organic frameworks (MOFs), this unique class of crystalline, porous materials has garnered increasing attention in a wide variety of applications such as gas storage and separation, catalysis, enzyme immobilization, drug delivery, water capture, and...

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Zhang X, Chen Z, Liu X, et al. A historical overview of the activation and porosity of metal-organic frameworks. Chem Soc Rev. 2020;49(20):7406-7427doi: 10.1039/d0cs00997k.
Zhang, X., Chen, Z., Liu, X., Hanna, S. L., Wang, X., Taheri-Ledari, R., Maleki, A., Li, P., & Farha, O. K. (2020). A historical overview of the activation and porosity of metal-organic frameworks. Chemical Society reviews, 49(20), 7406-7427. https://doi.org/10.1039/d0cs00997k
Zhang, Xuan, et al. "A historical overview of the activation and porosity of metal-organic frameworks." Chemical Society reviews vol. 49,20 (2020): 7406-7427. doi: https://doi.org/10.1039/d0cs00997k
Zhang X, Chen Z, Liu X, Hanna SL, Wang X, Taheri-Ledari R, Maleki A, Li P, Farha OK. A historical overview of the activation and porosity of metal-organic frameworks. Chem Soc Rev. 2020 Oct 19;49(20):7406-7427. doi: 10.1039/d0cs00997k. PMID: 32955065.
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Heterometal incorporation in NH.

Chemical communications (Cambridge, England)

Hanna L, Long CL, Zhang X, Lockard JV.
PMID: 33000804
Chem Commun (Camb). 2020 Oct 01;56(78):11597-11600. doi: 10.1039/d0cc05339b.

Optical and X-ray spectroscopy studies reveal the location and role of Fe3+ sites incorporated through direct synthesis in NH2-MIL-125(Ti). Fe K-edge XAS analysis confirms its metal-oxo cluster node coordination while time-resolved optical and X-ray transient absorption studies disclose its...

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Hanna L, Long CL, Zhang X, et al. Heterometal incorporation in NH. Chem Commun (Camb). 2020;56(78):11597-11600doi: 10.1039/d0cc05339b.
Hanna, L., Long, C. L., Zhang, X., & Lockard, J. V. (2020). Heterometal incorporation in NH. Chemical communications (Cambridge, England), 56(78), 11597-11600. https://doi.org/10.1039/d0cc05339b
Hanna, Lauren, et al. "Heterometal incorporation in NH." Chemical communications (Cambridge, England) vol. 56,78 (2020): 11597-11600. doi: https://doi.org/10.1039/d0cc05339b
Hanna L, Long CL, Zhang X, Lockard JV. Heterometal incorporation in NH. Chem Commun (Camb). 2020 Oct 01;56(78):11597-11600. doi: 10.1039/d0cc05339b. PMID: 33000804.
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A rare case report of apixaban-induced lichenoid eruption.

Therapeutic advances in drug safety

Patil T, Hanna S, Torre W.
PMID: 32874531
Ther Adv Drug Saf. 2020 Aug 17;11:2042098620937884. doi: 10.1177/2042098620937884. eCollection 2020.

No abstract available.

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Patil T, Hanna S, Torre W. A rare case report of apixaban-induced lichenoid eruption. Ther Adv Drug Saf. 2020;11:2042098620937884doi: 10.1177/2042098620937884.
Patil, T., Hanna, S., & Torre, W. (2020). A rare case report of apixaban-induced lichenoid eruption. Therapeutic advances in drug safety, 112042098620937884. https://doi.org/10.1177/2042098620937884
Patil, Tanvi, et al. "A rare case report of apixaban-induced lichenoid eruption." Therapeutic advances in drug safety vol. 11 (2020): 2042098620937884. doi: https://doi.org/10.1177/2042098620937884
Patil T, Hanna S, Torre W. A rare case report of apixaban-induced lichenoid eruption. Ther Adv Drug Saf. 2020 Aug 17;11:2042098620937884. doi: 10.1177/2042098620937884. eCollection 2020. PMID: 32874531; PMCID: PMC7436782.
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Rictor/mTORC2 facilitates central regulation of energy and glucose homeostasis.

Molecular metabolism

Kocalis HE, Hagan SL, George L, Turney MK, Siuta MA, Laryea GN, Morris LC, Muglia LJ, Printz RL, Stanwood GD, Niswender KD.
PMID: 24944899
Mol Metab. 2014 Feb 19;3(4):394-407. doi: 10.1016/j.molmet.2014.01.014. eCollection 2014 Jul.

Insulin signaling in the central nervous system (CNS) regulates energy balance and peripheral glucose homeostasis. Rictor is a key regulatory/structural subunit of the mTORC2 complex and is required for hydrophobic motif site phosphorylation of Akt at serine 473. To...

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Kocalis HE, Hagan SL, George L, et al. Rictor/mTORC2 facilitates central regulation of energy and glucose homeostasis. Mol Metab. 2014;3(4):394-407doi: 10.1016/j.molmet.2014.01.014.
Kocalis, H. E., Hagan, S. L., George, L., Turney, M. K., Siuta, M. A., Laryea, G. N., Morris, L. C., Muglia, L. J., Printz, R. L., Stanwood, G. D., & Niswender, K. D. (2014). Rictor/mTORC2 facilitates central regulation of energy and glucose homeostasis. Molecular metabolism, 3(4), 394-407. https://doi.org/10.1016/j.molmet.2014.01.014
Kocalis, Heidi E, et al. "Rictor/mTORC2 facilitates central regulation of energy and glucose homeostasis." Molecular metabolism vol. 3,4 (2014): 394-407. doi: https://doi.org/10.1016/j.molmet.2014.01.014
Kocalis HE, Hagan SL, George L, Turney MK, Siuta MA, Laryea GN, Morris LC, Muglia LJ, Printz RL, Stanwood GD, Niswender KD. Rictor/mTORC2 facilitates central regulation of energy and glucose homeostasis. Mol Metab. 2014 Feb 19;3(4):394-407. doi: 10.1016/j.molmet.2014.01.014. eCollection 2014 Jul. PMID: 24944899; PMCID: PMC4060224.
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Molecular Characterization of Prostate Cancers in the Precision Medicine Era.

Cancers

Giunta EF, Annaratone L, Bollito E, Porpiglia F, Cereda M, Banna GL, Mosca A, Marchiò C, Rescigno P.
PMID: 34638258
Cancers (Basel). 2021 Sep 24;13(19). doi: 10.3390/cancers13194771.

Prostate cancer (PCa) therapy has been recently revolutionized by the approval of new therapeutic agents in the metastatic setting. However, the optimal therapeutic strategy in such patients should be individualized in the light of prognostic and predictive molecular factors,...

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Giunta EF, Annaratone L, Bollito E, et al. Molecular Characterization of Prostate Cancers in the Precision Medicine Era. Cancers (Basel). 2021;13(19)doi: 10.3390/cancers13194771.
Giunta, E. F., Annaratone, L., Bollito, E., Porpiglia, F., Cereda, M., Banna, G. L., Mosca, A., Marchiò, C., & Rescigno, P. (2021). Molecular Characterization of Prostate Cancers in the Precision Medicine Era. Cancers, 13(19), . https://doi.org/10.3390/cancers13194771
Giunta, Emilio Francesco, et al. "Molecular Characterization of Prostate Cancers in the Precision Medicine Era." Cancers vol. 13,19 (2021). doi: https://doi.org/10.3390/cancers13194771
Giunta EF, Annaratone L, Bollito E, Porpiglia F, Cereda M, Banna GL, Mosca A, Marchiò C, Rescigno P. Molecular Characterization of Prostate Cancers in the Precision Medicine Era. Cancers (Basel). 2021 Sep 24;13(19). doi: 10.3390/cancers13194771. PMID: 34638258; PMCID: PMC8507555.
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