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Proteomic profiling of MIS-C patients indicates heterogeneity relating to interferon gamma dysregulation and vascular endothelial dysfunction.

Nature communications

Diorio C, Shraim R, Vella LA, Giles JR, Baxter AE, Oldridge DA, Canna SW, Henrickson SE, McNerney KO, Balamuth F, Burudpakdee C, Lee J, Leng T, Farrel A, Lambert MP, Sullivan KE, Wherry EJ, Teachey DT, Bassiri H, Behrens EM.
PMID: 34893640
Nat Commun. 2021 Dec 10;12(1):7222. doi: 10.1038/s41467-021-27544-6.

Multi-system Inflammatory Syndrome in Children (MIS-C) is a major complication of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection in pediatric patients. Weeks after an often mild or asymptomatic initial infection with SARS-CoV-2 children may present with a severe...

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Diorio C, Shraim R, Vella LA, et al. Proteomic profiling of MIS-C patients indicates heterogeneity relating to interferon gamma dysregulation and vascular endothelial dysfunction. Nat Commun. 2021;12(1):7222doi: 10.1038/s41467-021-27544-6.
Diorio, C., Shraim, R., Vella, L. A., Giles, J. R., Baxter, A. E., Oldridge, D. A., Canna, S. W., Henrickson, S. E., McNerney, K. O., Balamuth, F., Burudpakdee, C., Lee, J., Leng, T., Farrel, A., Lambert, M. P., Sullivan, K. E., Wherry, E. J., Teachey, D. T., Bassiri, H., & Behrens, E. M. (2021). Proteomic profiling of MIS-C patients indicates heterogeneity relating to interferon gamma dysregulation and vascular endothelial dysfunction. Nature communications, 12(1), 7222. https://doi.org/10.1038/s41467-021-27544-6
Diorio, Caroline, et al. "Proteomic profiling of MIS-C patients indicates heterogeneity relating to interferon gamma dysregulation and vascular endothelial dysfunction." Nature communications vol. 12,1 (2021): 7222. doi: https://doi.org/10.1038/s41467-021-27544-6
Diorio C, Shraim R, Vella LA, Giles JR, Baxter AE, Oldridge DA, Canna SW, Henrickson SE, McNerney KO, Balamuth F, Burudpakdee C, Lee J, Leng T, Farrel A, Lambert MP, Sullivan KE, Wherry EJ, Teachey DT, Bassiri H, Behrens EM. Proteomic profiling of MIS-C patients indicates heterogeneity relating to interferon gamma dysregulation and vascular endothelial dysfunction. Nat Commun. 2021 Dec 10;12(1):7222. doi: 10.1038/s41467-021-27544-6. PMID: 34893640.
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3D Non-Local Neural Network: A Non-Invasive Biomarker for Immunotherapy Treatment Outcome Prediction. Case-Study: Metastatic Urothelial Carcinoma.

Journal of imaging

Rundo F, Banna GL, Prezzavento L, Trenta F, Conoci S, Battiato S.
PMID: 34460530
J Imaging. 2020 Dec 03;6(12). doi: 10.3390/jimaging6120133.

Immunotherapy is regarded as one of the most significant breakthroughs in cancer treatment. Unfortunately, only a small percentage of patients respond properly to the treatment. Moreover, to date, there are no efficient bio-markers able to early discriminate the patients...

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Rundo F, Banna GL, Prezzavento L, et al. 3D Non-Local Neural Network: A Non-Invasive Biomarker for Immunotherapy Treatment Outcome Prediction. Case-Study: Metastatic Urothelial Carcinoma. J Imaging. 2020;6(12)doi: 10.3390/jimaging6120133.
Rundo, F., Banna, G. L., Prezzavento, L., Trenta, F., Conoci, S., & Battiato, S. (2020). 3D Non-Local Neural Network: A Non-Invasive Biomarker for Immunotherapy Treatment Outcome Prediction. Case-Study: Metastatic Urothelial Carcinoma. Journal of imaging, 6(12), . https://doi.org/10.3390/jimaging6120133
Rundo, Francesco, et al. "3D Non-Local Neural Network: A Non-Invasive Biomarker for Immunotherapy Treatment Outcome Prediction. Case-Study: Metastatic Urothelial Carcinoma." Journal of imaging vol. 6,12 (2020). doi: https://doi.org/10.3390/jimaging6120133
Rundo F, Banna GL, Prezzavento L, Trenta F, Conoci S, Battiato S. 3D Non-Local Neural Network: A Non-Invasive Biomarker for Immunotherapy Treatment Outcome Prediction. Case-Study: Metastatic Urothelial Carcinoma. J Imaging. 2020 Dec 03;6(12). doi: 10.3390/jimaging6120133. PMID: 34460530; PMCID: PMC8321180.
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Coalescence and splitting of confined droplets at microfluidic junctions.

Lab on a chip

Christopher GF, Bergstein J, End NB, Poon M, Nguyen C, Anna SL.
PMID: 19350092
Lab Chip. 2009 Apr 21;9(8):1102-9. doi: 10.1039/b813062k. Epub 2009 Jan 23.

The ability to merge two droplets is an important component of droplet-based lab-on-a-chip devices, yet flow-induced coalescence is difficult to achieve due to long film drainage times compared with relatively short residence times. We examine droplet collisions at a...

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Christopher GF, Bergstein J, End NB, et al. Coalescence and splitting of confined droplets at microfluidic junctions. Lab Chip. 2009;9(8):1102-9doi: 10.1039/b813062k.
Christopher, G. F., Bergstein, J., End, N. B., Poon, M., Nguyen, C., & Anna, S. L. (2009). Coalescence and splitting of confined droplets at microfluidic junctions. Lab on a chip, 9(8), 1102-9. https://doi.org/10.1039/b813062k
Christopher, G F, et al. "Coalescence and splitting of confined droplets at microfluidic junctions." Lab on a chip vol. 9,8 (2009): 1102-9. doi: https://doi.org/10.1039/b813062k
Christopher GF, Bergstein J, End NB, Poon M, Nguyen C, Anna SL. Coalescence and splitting of confined droplets at microfluidic junctions. Lab Chip. 2009 Apr 21;9(8):1102-9. doi: 10.1039/b813062k. Epub 2009 Jan 23. PMID: 19350092.
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Activated but functionally impaired memory Tregs are expanded in slow progressors to type 1 diabetes.

Diabetologia

Boldison J, Long AE, Aitken RJ, Wilson IV, Megson C, Hanna SJ, Wong FS, Gillespie KM.
PMID: 34709423
Diabetologia. 2022 Feb;65(2):343-355. doi: 10.1007/s00125-021-05595-0. Epub 2021 Oct 28.

AIMS/HYPOTHESIS: Slow progressors to type 1 diabetes are individuals positive for multiple pancreatic islet autoantibodies who have remained diabetes-free for at least 10 years; regulation of the autoimmune response is understudied in this group. Here, we profile CD4METHODS: Peripheral...

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Boldison J, Long AE, Aitken RJ, et al. Activated but functionally impaired memory Tregs are expanded in slow progressors to type 1 diabetes. Diabetologia. 2021;65(2):343-355doi: 10.1007/s00125-021-05595-0.
Boldison, J., Long, A. E., Aitken, R. J., Wilson, I. V., Megson, C., Hanna, S. J., Wong, F. S., & Gillespie, K. M. (2022). Activated but functionally impaired memory Tregs are expanded in slow progressors to type 1 diabetes. Diabetologia, 65(2), 343-355. https://doi.org/10.1007/s00125-021-05595-0
Boldison, Joanne, et al. "Activated but functionally impaired memory Tregs are expanded in slow progressors to type 1 diabetes." Diabetologia vol. 65,2 (2022): 343-355. doi: https://doi.org/10.1007/s00125-021-05595-0
Boldison J, Long AE, Aitken RJ, Wilson IV, Megson C, Hanna SJ, Wong FS, Gillespie KM. Activated but functionally impaired memory Tregs are expanded in slow progressors to type 1 diabetes. Diabetologia. 2022 Feb;65(2):343-355. doi: 10.1007/s00125-021-05595-0. Epub 2021 Oct 28. PMID: 34709423.
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Cancers of the appendix: review of the literatures.

ISRN oncology

Ruoff C, Hanna L, Zhi W, Shahzad G, Gotlieb V, Saif MW.
PMID: 22084738
ISRN Oncol. 2011;2011:728579. doi: 10.5402/2011/728579. Epub 2011 Aug 11.

Cancers of the appendix are rare. Most of them are found accidentally on appendectomies performed for appendicitis. When reviewed, majority of the tumors were carcinoid, adenoma, and lymphoma. Adenocarcinomas of appendix are only 0.08% of all cancers and the...

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Ruoff C, Hanna L, Zhi W, et al. Cancers of the appendix: review of the literatures. ISRN Oncol. 2011;2011:728579doi: 10.5402/2011/728579.
Ruoff, C., Hanna, L., Zhi, W., Shahzad, G., Gotlieb, V., & Saif, M. W. (2011). Cancers of the appendix: review of the literatures. ISRN oncology, 2011728579. https://doi.org/10.5402/2011/728579
Ruoff, Carl, et al. "Cancers of the appendix: review of the literatures." ISRN oncology vol. 2011 (2011): 728579. doi: https://doi.org/10.5402/2011/728579
Ruoff C, Hanna L, Zhi W, Shahzad G, Gotlieb V, Saif MW. Cancers of the appendix: review of the literatures. ISRN Oncol. 2011;2011:728579. doi: 10.5402/2011/728579. Epub 2011 Aug 11. PMID: 22084738; PMCID: PMC3200132.
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Variation in Early Management Practices in Moderate-to-Severe ARDS in the United States: The Severe ARDS: Generating Evidence Study.

Chest

Qadir N, Bartz RR, Cooter ML, Hough CL, Lanspa MJ, Banner-Goodspeed VM, Chen JT, Giovanni S, Gomaa D, Sjoding MW, Hajizadeh N, Komisarow J, Duggal A, Khanna AK, Kashyap R, Khan A, Chang SY, Tonna JE, Anderson HL, Liebler JM, Mosier JM, Morris PE, Genthon A, Louh IK, Tidswell M, Stephens RS, Esper AM, Dries DJ, Martinez A, Schreyer KE, Bender W, Tiwari A, Guru PK, Hanna S, Gong MN, Park PK.
PMID: 34089739
Chest. 2021 Oct;160(4):1304-1315. doi: 10.1016/j.chest.2021.05.047. Epub 2021 Jun 04.

BACKGROUND: Although specific interventions previously demonstrated benefit in patients with ARDS, use of these interventions is inconsistent, and patient mortality remains high. The impact of variability in center management practices on ARDS mortality rates remains unknown.RESEARCH QUESTION: What is...

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Qadir N, Bartz RR, Cooter ML, et al. Variation in Early Management Practices in Moderate-to-Severe ARDS in the United States: The Severe ARDS: Generating Evidence Study. Chest. 2021;160(4):1304-1315doi: 10.1016/j.chest.2021.05.047.
Qadir, N., Bartz, R. R., Cooter, M. L., Hough, C. L., Lanspa, M. J., Banner-Goodspeed, V. M., Chen, J. T., Giovanni, S., Gomaa, D., Sjoding, M. W., Hajizadeh, N., Komisarow, J., Duggal, A., Khanna, A. K., Kashyap, R., Khan, A., Chang, S. Y., Tonna, J. E., Anderson, H. L., Liebler, J. M., Mosier, J. M., Morris, P. E., Genthon, A., Louh, I. K., Tidswell, M., Stephens, R. S., Esper, A. M., Dries, D. J., Martinez, A., Schreyer, K. E., Bender, W., Tiwari, A., Guru, P. K., Hanna, S., Gong, M. N., Park, P. K. (2021). Variation in Early Management Practices in Moderate-to-Severe ARDS in the United States: The Severe ARDS: Generating Evidence Study. Chest, 160(4), 1304-1315. https://doi.org/10.1016/j.chest.2021.05.047
Qadir, Nida, et al. "Variation in Early Management Practices in Moderate-to-Severe ARDS in the United States: The Severe ARDS: Generating Evidence Study." Chest vol. 160,4 (2021): 1304-1315. doi: https://doi.org/10.1016/j.chest.2021.05.047
Qadir N, Bartz RR, Cooter ML, Hough CL, Lanspa MJ, Banner-Goodspeed VM, Chen JT, Giovanni S, Gomaa D, Sjoding MW, Hajizadeh N, Komisarow J, Duggal A, Khanna AK, Kashyap R, Khan A, Chang SY, Tonna JE, Anderson HL, Liebler JM, Mosier JM, Morris PE, Genthon A, Louh IK, Tidswell M, Stephens RS, Esper AM, Dries DJ, Martinez A, Schreyer KE, Bender W, Tiwari A, Guru PK, Hanna S, Gong MN, Park PK. Variation in Early Management Practices in Moderate-to-Severe ARDS in the United States: The Severe ARDS: Generating Evidence Study. Chest. 2021 Oct;160(4):1304-1315. doi: 10.1016/j.chest.2021.05.047. Epub 2021 Jun 04. PMID: 34089739; PMCID: PMC8176896.
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T2 relaxation measurement with solvent suppression and implications to solvent suppression in general.

Magnetic resonance in chemistry : MRC

Hoffmann MM, Sobstyl HS, Badali VA.
PMID: 19373850
Magn Reson Chem. 2009 Jul;47(7):593-600. doi: 10.1002/mrc.2434.

A number of suppression pulse sequences including Excitation Sculpting and WATERGATE were incorporated into the standard Carr-Purcell-Meiboom-Gill (CPMG) program for T(2) measurement and experimentally evaluated. The chosen suppression schemes were of varying complexity encompassing pulse program elements, such as...

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Hoffmann MM, Sobstyl HS, Badali VA. T2 relaxation measurement with solvent suppression and implications to solvent suppression in general. Magn Reson Chem. 2009;47(7):593-600doi: 10.1002/mrc.2434.
Hoffmann, M. M., Sobstyl, H. S., & Badali, V. A. (2009). T2 relaxation measurement with solvent suppression and implications to solvent suppression in general. Magnetic resonance in chemistry : MRC, 47(7), 593-600. https://doi.org/10.1002/mrc.2434
Hoffmann, Markus M, et al. "T2 relaxation measurement with solvent suppression and implications to solvent suppression in general." Magnetic resonance in chemistry : MRC vol. 47,7 (2009): 593-600. doi: https://doi.org/10.1002/mrc.2434
Hoffmann MM, Sobstyl HS, Badali VA. T2 relaxation measurement with solvent suppression and implications to solvent suppression in general. Magn Reson Chem. 2009 Jul;47(7):593-600. doi: 10.1002/mrc.2434. PMID: 19373850.
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Short-term analysis on the combined use of sugarcane bagasse ash and rice husk ash as supplementary cementitious material in concrete production.

Environmental science and pollution research international

Channa SH, Mangi SA, Bheel N, Soomro FA, Khahro SH.
PMID: 34387820
Environ Sci Pollut Res Int. 2022 Jan;29(3):3555-3564. doi: 10.1007/s11356-021-15877-0. Epub 2021 Aug 13.

Globally, concrete is widely implemented as a construction material and is progressively being utilized because of growth in urbanization. However, limited resources and gradual depravity of the environment are forcing the research community to obtain alternative materials from large...

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Channa SH, Mangi SA, Bheel N, et al. Short-term analysis on the combined use of sugarcane bagasse ash and rice husk ash as supplementary cementitious material in concrete production. Environ Sci Pollut Res Int. 2021;29(3):3555-3564doi: 10.1007/s11356-021-15877-0.
Channa, S. H., Mangi, S. A., Bheel, N., Soomro, F. A., & Khahro, S. H. (2022). Short-term analysis on the combined use of sugarcane bagasse ash and rice husk ash as supplementary cementitious material in concrete production. Environmental science and pollution research international, 29(3), 3555-3564. https://doi.org/10.1007/s11356-021-15877-0
Channa, Shahid Hussain, et al. "Short-term analysis on the combined use of sugarcane bagasse ash and rice husk ash as supplementary cementitious material in concrete production." Environmental science and pollution research international vol. 29,3 (2022): 3555-3564. doi: https://doi.org/10.1007/s11356-021-15877-0
Channa SH, Mangi SA, Bheel N, Soomro FA, Khahro SH. Short-term analysis on the combined use of sugarcane bagasse ash and rice husk ash as supplementary cementitious material in concrete production. Environ Sci Pollut Res Int. 2022 Jan;29(3):3555-3564. doi: 10.1007/s11356-021-15877-0. Epub 2021 Aug 13. PMID: 34387820.
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The detection of germline and somatic BRCA1/2 genetic variants through parallel testing of patients with high-grade serous ovarian cancer: a national retrospective audit.

BJOG : an international journal of obstetrics and gynaecology

Frugtniet B, Morgan S, Murray A, Palmer-Smith S, White R, Jones R, Hanna L, Fuller C, Hudson E, Mullard A, Quinton AE.
PMID: 34657373
BJOG. 2021 Oct 17; doi: 10.1111/1471-0528.16975. Epub 2021 Oct 17.

OBJECTIVE: To determine the frequency of germline and somatic pathogenic BRCA1 and BRCA2 variants in patients with high-grade serous ovarian cancer tested by next-generation sequencing (NGS), with the aim of defining the best strategy to be implemented in future...

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Frugtniet B, Morgan S, Murray A, et al. The detection of germline and somatic BRCA1/2 genetic variants through parallel testing of patients with high-grade serous ovarian cancer: a national retrospective audit. BJOG. 2021;doi: 10.1111/1471-0528.16975.
Frugtniet, B., Morgan, S., Murray, A., Palmer-Smith, S., White, R., Jones, R., Hanna, L., Fuller, C., Hudson, E., Mullard, A., & Quinton, A. E. (2021). The detection of germline and somatic BRCA1/2 genetic variants through parallel testing of patients with high-grade serous ovarian cancer: a national retrospective audit. BJOG : an international journal of obstetrics and gynaecology, . https://doi.org/10.1111/1471-0528.16975
Frugtniet, B, et al. "The detection of germline and somatic BRCA1/2 genetic variants through parallel testing of patients with high-grade serous ovarian cancer: a national retrospective audit." BJOG : an international journal of obstetrics and gynaecology vol. (2021). doi: https://doi.org/10.1111/1471-0528.16975
Frugtniet B, Morgan S, Murray A, Palmer-Smith S, White R, Jones R, Hanna L, Fuller C, Hudson E, Mullard A, Quinton AE. The detection of germline and somatic BRCA1/2 genetic variants through parallel testing of patients with high-grade serous ovarian cancer: a national retrospective audit. BJOG. 2021 Oct 17; doi: 10.1111/1471-0528.16975. Epub 2021 Oct 17. PMID: 34657373.
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Systematic Review on the Efficacy and Safety of Oral Janus Kinase Inhibitors for the Treatment of Atopic Dermatitis.

Frontiers in medicine

Le M, Berman-Rosa M, Ghazawi FM, Bourcier M, Fiorillo L, Gooderham M, Guenther L, Hanna S, Hong HC, Landells I, Lansang P, Marcoux D, Wiseman MC, Yeung J, Lynde C, Litvinov IV.
PMID: 34540860
Front Med (Lausanne). 2021 Sep 01;8:682547. doi: 10.3389/fmed.2021.682547. eCollection 2021.

No abstract available.

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Le M, Berman-Rosa M, Ghazawi FM, et al. Systematic Review on the Efficacy and Safety of Oral Janus Kinase Inhibitors for the Treatment of Atopic Dermatitis. Front Med (Lausanne). 2021;8:682547doi: 10.3389/fmed.2021.682547.
Le, M., Berman-Rosa, M., Ghazawi, F. M., Bourcier, M., Fiorillo, L., Gooderham, M., Guenther, L., Hanna, S., Hong, H. C., Landells, I., Lansang, P., Marcoux, D., Wiseman, M. C., Yeung, J., Lynde, C., & Litvinov, I. V. (2021). Systematic Review on the Efficacy and Safety of Oral Janus Kinase Inhibitors for the Treatment of Atopic Dermatitis. Frontiers in medicine, 8682547. https://doi.org/10.3389/fmed.2021.682547
Le, Michelle, et al. "Systematic Review on the Efficacy and Safety of Oral Janus Kinase Inhibitors for the Treatment of Atopic Dermatitis." Frontiers in medicine vol. 8 (2021): 682547. doi: https://doi.org/10.3389/fmed.2021.682547
Le M, Berman-Rosa M, Ghazawi FM, Bourcier M, Fiorillo L, Gooderham M, Guenther L, Hanna S, Hong HC, Landells I, Lansang P, Marcoux D, Wiseman MC, Yeung J, Lynde C, Litvinov IV. Systematic Review on the Efficacy and Safety of Oral Janus Kinase Inhibitors for the Treatment of Atopic Dermatitis. Front Med (Lausanne). 2021 Sep 01;8:682547. doi: 10.3389/fmed.2021.682547. eCollection 2021. PMID: 34540860; PMCID: PMC8440866.
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Transport and dispersion of tracers simulating COVID-19 aerosols in passenger aircraft.

Indoor air

Hanna S.
PMID: 34921460
Indoor Air. 2021 Dec 17; doi: 10.1111/ina.12974. Epub 2021 Dec 17.

Many laboratory experiments and model development activities have been underway to better estimate the risk of a person indoors becoming infected with COVID-19. The current paper focusses on the near-field (distances 

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Hanna S. Transport and dispersion of tracers simulating COVID-19 aerosols in passenger aircraft. Indoor Air. 2021;doi: 10.1111/ina.12974.
Hanna, S. (2021). Transport and dispersion of tracers simulating COVID-19 aerosols in passenger aircraft. Indoor air, . https://doi.org/10.1111/ina.12974
Hanna, Steven. "Transport and dispersion of tracers simulating COVID-19 aerosols in passenger aircraft." Indoor air vol. (2021). doi: https://doi.org/10.1111/ina.12974
Hanna S. Transport and dispersion of tracers simulating COVID-19 aerosols in passenger aircraft. Indoor Air. 2021 Dec 17; doi: 10.1111/ina.12974. Epub 2021 Dec 17. PMID: 34921460.
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Cross-cultural adaptation and translation of the Constant Murley Score into Arabic.

SICOT-J

Maqdes A, Hanna SS, Bouhamra AK, Khaja AF.
PMID: 33220719
SICOT J. 2020;6:44. doi: 10.1051/sicotj/2020042. Epub 2020 Oct 20.

INTRODUCTION: Shoulder pain is a major disorder of the musculoskeletal system. To the best of our knowledge, there is no documentation of an Arabic version of the shoulder disability and pain measurements. Constant Murley Score (CMS) is one of...

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Maqdes A, Hanna SS, Bouhamra AK, et al. Cross-cultural adaptation and translation of the Constant Murley Score into Arabic. SICOT J. 2020;6:44doi: 10.1051/sicotj/2020042.
Maqdes, A., Hanna, S. S., Bouhamra, A. K., & Khaja, A. F. (2020). Cross-cultural adaptation and translation of the Constant Murley Score into Arabic. SICOT-J, 644. https://doi.org/10.1051/sicotj/2020042
Maqdes, Ali, et al. "Cross-cultural adaptation and translation of the Constant Murley Score into Arabic." SICOT-J vol. 6 (2020): 44. doi: https://doi.org/10.1051/sicotj/2020042
Maqdes A, Hanna SS, Bouhamra AK, Khaja AF. Cross-cultural adaptation and translation of the Constant Murley Score into Arabic. SICOT J. 2020;6:44. doi: 10.1051/sicotj/2020042. Epub 2020 Oct 20. PMID: 33220719; PMCID: PMC7680506.
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