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Showing 25 to 36 of 216 entries
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Uniportal Endoscopic Lumbar Interbody Fusion.

Neurospine

Wagner R, Haefner M.
PMID: 32746525
Neurospine. 2020 Jul;17:S120-S128. doi: 10.14245/ns.2040130.065. Epub 2020 Jul 31.

The cause of radiculopathy is the compression of the nerve root which can be secondary to sliding of the vertebra and reduced disc height. In some patients, decompression alone does not resolve this problem. We describe the uniportal endoscopic...

Efficacy and safety of a new low-volume PEG with citrate and simethicone bowel preparation for colonoscopy (Clensia): a multicenter randomized observer-blind clinical trial vs. a low-volume PEG with ascorbic acid (PEG-ASC).

Endoscopy international open

Kump P, Hassan C, Spada C, Brownstone E, Datz C, Haefner M, Renner F, Schoefl R, Schreiber F.
PMID: 30083580
Endosc Int Open. 2018 Aug;6(8):E907-E913. doi: 10.1055/a-0624-2266. Epub 2018 Aug 01.

BACKGROUND AND STUDY AIMS : Quality of inspection during colonoscopy is strictly related to the level of cleansing. High-volume (PEG-based) solutions are highly effective and safe, but their high volume affects tolerability and compliance. The aim of this study...

Epigenetic and transcriptional analysis reveals a core transcriptional program conserved in clonal prostate cancer metastases.

Molecular oncology

Severson TM, Zhu Y, De Marzo AM, Jones T, Simons JW, Nelson WG, Yegnasubramanian S, Freedman ML, Wessels L, Bergman AM, Haffner MC, Zwart W.
PMID: 33576154
Mol Oncol. 2021 Jul;15(7):1942-1955. doi: 10.1002/1878-0261.12923. Epub 2021 Mar 11.

The epigenomic regulation of transcriptional programs in metastatic prostate cancer is poorly understood. We studied the epigenomic landscape of prostate cancer drivers using transcriptional profiling and ChIP-seq in four clonal metastatic tumors derived from a single prostate cancer patient....

Elevated expression of the colony-stimulating factor 1 (CSF1) induces prostatic intraepithelial neoplasia dependent of epithelial-Gp130.

Oncogene

Kwon OJ, Zhang B, Jia D, Zhang L, Wei X, Zhou Z, Liu D, Huynh KT, Zhang K, Zhang Y, Labhart P, Sboner A, Barbieri C, Haffner MC, Creighton CJ, Xin L.
PMID: 34999736
Oncogene. 2022 Jan 08; doi: 10.1038/s41388-021-02169-7. Epub 2022 Jan 08.

Macrophages are increased in human benign prostatic hyperplasia and prostate cancer. We generate a Pb-Csf1 mouse model with prostate-specific overexpression of macrophage colony-stimulating factor (M-Csf/Csf1). Csf1 overexpression promotes immune cell infiltration into the prostate, modulates the macrophage polarity in...

Noninvasive Detection of Intracranial Hypertension by Novel Ultrasound Time-Harmonic Elastography.

Investigative radiology

Kreft B, Tzschätzsch H, Shahryari M, Haffner P, Braun J, Sack I, Streitberger KJ.
PMID: 34380993
Invest Radiol. 2022 Feb 01;57(2):77-84. doi: 10.1097/RLI.0000000000000817.

OBJECTIVE: A method for measuring intracranial pressure (ICP) noninvasively has long been sought after in neurology and neurosurgery. Treatment failure in individuals presenting with unspecific symptoms such as headache, gait disturbance, or visual impairment occurring in response to increased...

Presenting features and long-term effects of growth hormone treatment of children with optic nerve hypoplasia/septo-optic dysplasia.

International journal of pediatric endocrinology

Vedin AM, Karlsson H, Fink C, Borchert M, Geffner ME.
PMID: 22085631
Int J Pediatr Endocrinol. 2011 Nov 15;2011(1):17. doi: 10.1186/1687-9856-2011-17.

BACKGROUND: Optic nerve hypoplasia (ONH) with/or without septo-optic dysplasia (SOD) is a known concomitant of congenital growth hormone deficiency (CGHD).METHODS: Demographic and longitudinal data from KIGS, the Pfizer International Growth Database, were compared between 395 subjects with ONH/SOD and...

Laser direct writing of rotationally symmetric high-resolution structures.

Applied optics

Haefner M, Pruss C, Osten W.
PMID: 22086024
Appl Opt. 2011 Nov 01;50(31):5983-9. doi: 10.1364/AO.50.005983.

We present a laser direct writing system for the efficient fabrication of high-resolution axicon structures. The setup makes use of scanning beam interference lithography incorporated with a fringe locking scheme for tight fringe phase control and allows us to...

Genomic attributes of homology-directed DNA repair deficiency in metastatic prostate cancer.

JCI insight

De Sarkar N, Dasgupta S, Chatterjee P, Coleman I, Ha G, Ang LS, Kohlbrenner EA, Frank SB, Nunez TA, Salipante SJ, Corey E, Morrissey C, Van Allen E, Schweizer MT, Haffner MC, Patel R, Hanratty B, Lucas JM, Dumpit RF, Pritchard CC, Montgomery RB, Nelson PS.
PMID: 34877933
JCI Insight. 2021 Dec 08;6(23). doi: 10.1172/jci.insight.152789.

Cancers with homology-directed DNA repair (HRR) deficiency exhibit high response rates to poly(ADP-ribose) polymerase inhibitors (PARPi) and platinum chemotherapy. Though mutations disrupting BRCA1 and BRCA2 associate with HRR deficiency (HRRd), patterns of genomic aberrations and mutation signatures may be...

[Options and limits of arthroscopic treatment of joint empyema].

Der Unfallchirurg

Osti M, Simkovic M, Haffner N.
PMID: 34874471
Unfallchirurg. 2021 Dec 07; doi: 10.1007/s00113-021-01111-6. Epub 2021 Dec 07.

Due to its low invasive nature, arthroscopy nowadays represents the gold standard in the treatment of native joint empyema. This article gives a summary of the literature with expert recommendations, reviews and case reports on arthroscopic treatment of native...

Resistance to androgen receptor signaling inhibition does not necessitate development of neuroendocrine prostate cancer.

JCI insight

Brennen WN, Zhu Y, Coleman IM, Dalrymple SL, Antony L, Patel RA, Hanratty B, Chikarmane R, Meeker AK, Zheng SL, Hooper JE, Luo J, De Marzo AM, Corey E, Xu J, Yegnasubramanian S, Haffner MC, Nelson PS, Nelson WG, Isaacs WB, Isaacs JT.
PMID: 33724955
JCI Insight. 2021 Apr 22;6(8). doi: 10.1172/jci.insight.146827.

Resistance to AR signaling inhibitors (ARSis) in a subset of metastatic castration-resistant prostate cancers (mCRPCs) occurs with the emergence of AR- neuroendocrine prostate cancer (NEPC) coupled with mutations/deletions in PTEN, TP53, and RB1 and the overexpression of DNMTs, EZH2,...

Gestational diabetes in women living with HIV in Botswana: lower rates with dolutegravir- than with efavirenz-based antiretroviral therapy.

HIV medicine

Mmasa KN, Powis K, Sun S, Makhema J, Mmalane M, Kgole S, Masasa G, Moyo S, Gerschenson M, Mohammed T, Legbedze J, Abrams EJ, Kurland IJ, Geffner ME, Jao J.
PMID: 34003565
HIV Med. 2021 Sep;22(8):715-722. doi: 10.1111/hiv.13120. Epub 2021 May 18.

BACKGROUND: There are few data on the prevalence of gestational diabetes (GDM) in pregnant women living with HIV (WLHIV) in sub-Saharan Africa, particularly those using integrase strand transfer inhibitors such as dolutegravir (DTG).METHODS: We prospectively enrolled pregnant WLHIV and...

CT scans better assess lateral wall morphology of "stable appearing" intertrochanteric (IT) femur fractures and predict early failure of sliding hip screw (SHS) fixation.

OTA international : the open access journal of orthopaedic trauma

Hecht G, Saiz AM, Shelton TJ, Haffner MR, Delman C, Shieh A, Hallare J, Bhatti S, Wolinsky P.
PMID: 34746672
OTA Int. 2021 Aug 09;4(3):e140. doi: 10.1097/OI9.0000000000000140. eCollection 2021 Sep.

To compare the efficacy of plain x-ray images and computed tomography (CT) to assess the morphology of the lateral wall (LW) component of intertrochanteric (IT) femur fractures and determine predictors of early fixation failure.DESIGN: Retrospective cohort study.SETTING: Level-one trauma...

Showing 25 to 36 of 216 entries