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Showing 133 to 136 of 136 entries
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Water Dynamics in a Peptide-appended Pillar[5]arene Artificial Channel in Lipid and Biomimetic Membranes.

Frontiers in chemistry

Barden DR, Vashisth H.
PMID: 34778209
Front Chem. 2021 Oct 29;9:753635. doi: 10.3389/fchem.2021.753635. eCollection 2021.

Peptide-appended Pillar[5]arene (PAP) is an artificial water channel that can be incorporated into lipid and polymeric membranes to achieve high permeability and enhanced selectivity for angstrom-scale separations [Shen et al.

Affinity-based protein profiling identifies vitamin D3 as a heat shock protein 70 antagonist that regulates hedgehog transduction in murine basal cell carcinoma.

European journal of medicinal chemistry

Wen J, Hadden MK.
PMID: 34844141
Eur J Med Chem. 2021 Nov 20;228:114005. doi: 10.1016/j.ejmech.2021.114005. Epub 2021 Nov 20.

Vitamin D3 (VD3) is a seco-steroid that inhibits the Hedgehog (Hh) signaling pathway. Initial studies suggested its anti-Hh activity results from direct inhibition of Smoothened, a seven-transmembrane cell surface receptor that is a key regulator of the Hh signaling...

Language dysfunction-associated EEG findings in patients with CAR-T related neurotoxicity.

BMJ neurology open

Sokolov E, Karschnia P, Benjamin R, Hadden RDM, Elwes RCD, Drummond L, Amin D, Paiva V, Pennisi A, Herlopian A, Frigault M, Sanderson R, Inam S, Cole AJ, Dietrich J.
PMID: 33681787
BMJ Neurol Open. 2020 Jun 18;2(1):e000054. doi: 10.1136/bmjno-2020-000054. eCollection 2020.

Chimeric antigen receptor-modified T cells (CAR-T) have emerged as a promising immunotherapeutic approach in relapsed/refractory haematolgical malignancies. Broader application is limited by unique toxicities, notably, neurotoxicity (NTX). Language dysfunction is among the most frequent symptoms of NTX, the underlying...

Real-Time Data Collection to Examine Relations Between Physical Activity and Affect in Adults With Mental Illness.

Journal of sport & exercise psychology

Madden DR, Nok Lam C, Redline B, Dzubur E, Rhoades H, Intille SS, Dunton GF, Henwood B.
PMID: 33022657
J Sport Exerc Psychol. 2020 Oct 06;1-8. doi: 10.1123/jsep.2019-0035. Epub 2020 Oct 06.

Adults with serious mental illness engage in limited physical activity, which contributes to significant health disparities. This study explored the use of both ecological momentary assessments (EMAs) and activity trackers in adults with serious mental illness to examine the...

Showing 133 to 136 of 136 entries