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Showing 445 to 449 of 449 entries
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Ripasudil eyedrops ameliorated bullous keratopathy complicated with cytomegalovirus corneal endotheliitis: a case report.

Ocular immunology and inflammation

Yoshida M, Yokokura S, Hariya T, Kobayashi W, Hashimoto K, Nakazawa T.
PMID: 34726564
Ocul Immunol Inflamm. 2021 Nov 02;1-4. doi: 10.1080/09273948.2021.1988114. Epub 2021 Nov 02.

PURPOSE: We describe a case of bullous keratopathy complicated with cytomegalovirus (CMV) corneal endotheliitis that was successfully treated with ripasudil eye drops.METHODS: A retrospective case report.RESULTS: A 65-year-old female patient diagnosed with CMV-associated anterior uveitis in the right eye...

Challenges for the Development of Extracellular Vesicle-Based Nucleic Acid Medicines.

Cancers

Kuriyama N, Yoshioka Y, Kikuchi S, Okamura A, Azuma N, Ochiya T.
PMID: 34885247
Cancers (Basel). 2021 Dec 06;13(23). doi: 10.3390/cancers13236137.

Nucleic acid drugs, such as siRNAs, antisense oligonucleotides, and miRNAs, exert their therapeutic effects by causing genetic changes in cells. However, there are various limitations in their delivery to target organs and cells, making their application to cancer treatment...

Longitudinal DNA methylation dynamics as a practical indicator in clinical epigenetics.

Clinical epigenetics

Komaki S, Ohmomo H, Hachiya T, Sutoh Y, Ono K, Furukawa R, Umekage S, Otsuka-Yamasaki Y, Tanno K, Sasaki M, Shimizu A.
PMID: 34903243
Clin Epigenetics. 2021 Dec 13;13(1):219. doi: 10.1186/s13148-021-01202-6.

BACKGROUND: One of the fundamental assumptions of DNA methylation in clinical epigenetics is that DNA methylation status can change over time with or without interplay with environmental and clinical conditions. However, little is known about how DNA methylation status...

Administration of cyclophosphamide to rats induces pica and potentiates 5-hydroxytryptamine synthesis in the intestine without causing severe intestinal injury.

Journal of pharmacological sciences

Kamiya A, Machida T, Hirano M, Machida M, Shiga S, Hamaue N, Hirafuji M, Iizuka K.
PMID: 34507634
J Pharmacol Sci. 2021 Nov;147(3):251-259. doi: 10.1016/j.jphs.2021.07.007. Epub 2021 Aug 02.

The effects of cyclophosphamide on 5-hydroxytryptamine (5-HT) synthesis in the intestinal tissue of rats were investigated. Rats received 120 mg/kg cyclophosphamide intraperitoneally as a single administration, and kaolin and food intake was measured by an automatic monitoring apparatus. Ileal...

Amorphous cellulose nanofiber supercapacitors.

Scientific reports

Fukuhara M, Kuroda T, Hasegawa F, Hashida T, Takeda M, Fujima N, Morita M, Nakatani T.
PMID: 33742038
Sci Rep. 2021 Mar 19;11(1):6436. doi: 10.1038/s41598-021-85901-3.

Despite the intense interest in cellulose nanofibers (CNFs) for biomedical and engineering applications, no research findings about the electrical energy storage of CNF have been reported yet. Here, we present the first electroadsorption effects of an amorphous cellulose nanofiber...

Showing 445 to 449 of 449 entries