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A Ruthenium(II)-Copper(II) Dyad for the Photocatalytic Oxygenation of Organic Substrates Mediated by Dioxygen Activation.

Angewandte Chemie (International ed. in English)

Iali W, Lanoe PH, Torelli S, Jouvenot D, Loiseau F, Lebrun C, Hamelin O, Ménage S.
PMID: 26013299
Angew Chem Int Ed Engl. 2015 Jul 13;54(29):8415-9. doi: 10.1002/anie.201501180. Epub 2015 May 27.

Dioxygen activation by copper complexes is a valuable method to achieve oxidation reactions for sustainable chemistry. The development of a catalytic system requires regeneration of the Cu(I) active redox state from Cu(II). This is usually achieved using extra reducers...

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Iali W, Lanoe PH, Torelli S, et al. A Ruthenium(II)-Copper(II) Dyad for the Photocatalytic Oxygenation of Organic Substrates Mediated by Dioxygen Activation. Angew Chem Int Ed Engl. 2015;54(29):8415-9doi: 10.1002/anie.201501180.
Iali, W., Lanoe, P. H., Torelli, S., Jouvenot, D., Loiseau, F., Lebrun, C., Hamelin, O., & Ménage, S. (2015). A Ruthenium(II)-Copper(II) Dyad for the Photocatalytic Oxygenation of Organic Substrates Mediated by Dioxygen Activation. Angewandte Chemie (International ed. in English), 54(29), 8415-9. https://doi.org/10.1002/anie.201501180
Iali, Wissam, et al. "A Ruthenium(II)-Copper(II) Dyad for the Photocatalytic Oxygenation of Organic Substrates Mediated by Dioxygen Activation." Angewandte Chemie (International ed. in English) vol. 54,29 (2015): 8415-9. doi: https://doi.org/10.1002/anie.201501180
Iali W, Lanoe PH, Torelli S, Jouvenot D, Loiseau F, Lebrun C, Hamelin O, Ménage S. A Ruthenium(II)-Copper(II) Dyad for the Photocatalytic Oxygenation of Organic Substrates Mediated by Dioxygen Activation. Angew Chem Int Ed Engl. 2015 Jul 13;54(29):8415-9. doi: 10.1002/anie.201501180. Epub 2015 May 27. PMID: 26013299.
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Impact of country of birth on genetic testing of metastatic lung adenocarcinomas in France: African women exhibit a mutational spectrum more similar to Asians than to Caucasians.

Oncotarget

Saffroy R, Morère JF, Bosselut N, Innominato PF, Hamelin J, Trédaniel J, Masse S, Dussaule-Duchatelle V, Balaton A, Validire P, Guettier C, Bouchahda M, Lemoine A.
PMID: 28881604
Oncotarget. 2017 Feb 07;8(31):50792-50803. doi: 10.18632/oncotarget.15132. eCollection 2017 Aug 01.

BACKGROUND: Limited data are available on the prevalence of oncogenic driver mutations in Caucasian populations, and especially in Europeans.AIM: To evaluate the targetable mutational spectra in unselected patients with lung adenocarcinoma in routine clinical practice from several French hospitals,...

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Saffroy R, Morère JF, Bosselut N, et al. Impact of country of birth on genetic testing of metastatic lung adenocarcinomas in France: African women exhibit a mutational spectrum more similar to Asians than to Caucasians. Oncotarget. 2017;8(31):50792-50803doi: 10.18632/oncotarget.15132.
Saffroy, R., Morère, J. F., Bosselut, N., Innominato, P. F., Hamelin, J., Trédaniel, J., Masse, S., Dussaule-Duchatelle, V., Balaton, A., Validire, P., Guettier, C., Bouchahda, M., & Lemoine, A. (2017). Impact of country of birth on genetic testing of metastatic lung adenocarcinomas in France: African women exhibit a mutational spectrum more similar to Asians than to Caucasians. Oncotarget, 8(31), 50792-50803. https://doi.org/10.18632/oncotarget.15132
Saffroy, Raphael, et al. "Impact of country of birth on genetic testing of metastatic lung adenocarcinomas in France: African women exhibit a mutational spectrum more similar to Asians than to Caucasians." Oncotarget vol. 8,31 (2017): 50792-50803. doi: https://doi.org/10.18632/oncotarget.15132
Saffroy R, Morère JF, Bosselut N, Innominato PF, Hamelin J, Trédaniel J, Masse S, Dussaule-Duchatelle V, Balaton A, Validire P, Guettier C, Bouchahda M, Lemoine A. Impact of country of birth on genetic testing of metastatic lung adenocarcinomas in France: African women exhibit a mutational spectrum more similar to Asians than to Caucasians. Oncotarget. 2017 Feb 07;8(31):50792-50803. doi: 10.18632/oncotarget.15132. eCollection 2017 Aug 01. PMID: 28881604; PMCID: PMC5584205.
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Detection of Brevetoxin in Human Plasma by ELISA.

Journal of analytical toxicology

Cunningham BR, Coleman RM, Schaefer AM, Hamelin EI, Johnson RC.
PMID: 33515246
J Anal Toxicol. 2021 Jan 30; doi: 10.1093/jat/bkab010. Epub 2021 Jan 30.

Florida red tides have become more common and persistent in and around the Gulf of Mexico. When in bloom, red tides can produce brevetoxins in high concentrations, leading to human exposures primarily through contaminated food and ocean spray. The...

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Cunningham BR, Coleman RM, Schaefer AM, et al. Detection of Brevetoxin in Human Plasma by ELISA. J Anal Toxicol. 2021;doi: 10.1093/jat/bkab010.
Cunningham, B. R., Coleman, R. M., Schaefer, A. M., Hamelin, E. I., & Johnson, R. C. (2021). Detection of Brevetoxin in Human Plasma by ELISA. Journal of analytical toxicology, . https://doi.org/10.1093/jat/bkab010
Cunningham, Brady R, et al. "Detection of Brevetoxin in Human Plasma by ELISA." Journal of analytical toxicology vol. (2021). doi: https://doi.org/10.1093/jat/bkab010
Cunningham BR, Coleman RM, Schaefer AM, Hamelin EI, Johnson RC. Detection of Brevetoxin in Human Plasma by ELISA. J Anal Toxicol. 2021 Jan 30; doi: 10.1093/jat/bkab010. Epub 2021 Jan 30. PMID: 33515246; PMCID: PMC8679180.
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Design of specific inhibitors of quinolinate synthase based on [4Fe-4S] cluster coordination.

Chemical communications (Cambridge, England)

Saez Cabodevilla J, Volbeda A, Hamelin O, Latour JM, Gigarel O, Clémancey M, Darnault C, Reichmann D, Amara P, Fontecilla-Camps JC, Ollagnier de Choudens S.
PMID: 30855610
Chem Commun (Camb). 2019 Mar 26;55(26):3725-3728. doi: 10.1039/c8cc09023h.

Quinolinate synthase (NadA) is a [4Fe-4S] cluster-containing enzyme involved in the formation of quinolinic acid, the precursor of the essential NAD coenzyme. Here, we report the synthesis and activity of derivatives of the first inhibitor of NadA. Using multidisciplinary...

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Saez Cabodevilla J, Volbeda A, Hamelin O, et al. Design of specific inhibitors of quinolinate synthase based on [4Fe-4S] cluster coordination. Chem Commun (Camb). 2019;55(26):3725-3728doi: 10.1039/c8cc09023h.
Saez Cabodevilla, J., Volbeda, A., Hamelin, O., Latour, J. M., Gigarel, O., Clémancey, M., Darnault, C., Reichmann, D., Amara, P., Fontecilla-Camps, J. C., & Ollagnier de Choudens, S. (2019). Design of specific inhibitors of quinolinate synthase based on [4Fe-4S] cluster coordination. Chemical communications (Cambridge, England), 55(26), 3725-3728. https://doi.org/10.1039/c8cc09023h
Saez Cabodevilla, Jaione, et al. "Design of specific inhibitors of quinolinate synthase based on [4Fe-4S] cluster coordination." Chemical communications (Cambridge, England) vol. 55,26 (2019): 3725-3728. doi: https://doi.org/10.1039/c8cc09023h
Saez Cabodevilla J, Volbeda A, Hamelin O, Latour JM, Gigarel O, Clémancey M, Darnault C, Reichmann D, Amara P, Fontecilla-Camps JC, Ollagnier de Choudens S. Design of specific inhibitors of quinolinate synthase based on [4Fe-4S] cluster coordination. Chem Commun (Camb). 2019 Mar 26;55(26):3725-3728. doi: 10.1039/c8cc09023h. PMID: 30855610.
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Prolonged Consumption of Sweetened Beverages Lastingly Deteriorates Cognitive Functions and Reward Processing in Mice.

Cerebral cortex (New York, N.Y. : 1991)

Hamelin H, Poizat G, Florian C, Kursa MB, Pittaras E, Callebert J, Rampon C, Taouis M, Hamed A, Granon S.
PMID: 34491298
Cereb Cortex. 2021 Sep 07; doi: 10.1093/cercor/bhab274. Epub 2021 Sep 07.

We investigated the detrimental effects of chronic consumption of sweet or sweetened beverages in mice. We report that consumption of beverages containing small amounts of sucrose during several weeks impaired reward systems. This is evidenced by robust changes in...

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Hamelin H, Poizat G, Florian C, et al. Prolonged Consumption of Sweetened Beverages Lastingly Deteriorates Cognitive Functions and Reward Processing in Mice. Cereb Cortex. 2021;doi: 10.1093/cercor/bhab274.
Hamelin, H., Poizat, G., Florian, C., Kursa, M. B., Pittaras, E., Callebert, J., Rampon, C., Taouis, M., Hamed, A., & Granon, S. (2021). Prolonged Consumption of Sweetened Beverages Lastingly Deteriorates Cognitive Functions and Reward Processing in Mice. Cerebral cortex (New York, N.Y. : 1991), . https://doi.org/10.1093/cercor/bhab274
Hamelin, Héloïse, et al. "Prolonged Consumption of Sweetened Beverages Lastingly Deteriorates Cognitive Functions and Reward Processing in Mice." Cerebral cortex (New York, N.Y. : 1991) vol. (2021). doi: https://doi.org/10.1093/cercor/bhab274
Hamelin H, Poizat G, Florian C, Kursa MB, Pittaras E, Callebert J, Rampon C, Taouis M, Hamed A, Granon S. Prolonged Consumption of Sweetened Beverages Lastingly Deteriorates Cognitive Functions and Reward Processing in Mice. Cereb Cortex. 2021 Sep 07; doi: 10.1093/cercor/bhab274. Epub 2021 Sep 07. PMID: 34491298.
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Reply to P. Gazzaniga et al.

JCO precision oncology

Bouchahda M, Saffroy R, Karaboué A, Hamelin J, Innominato P, Saliba F, Bosselut N, Lemoine A, Lévi F.
PMID: 34994602
JCO Precis Oncol. 2021 Nov;5:391-392. doi: 10.1200/PO.20.00465.

No abstract available.

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Bouchahda M, Saffroy R, Karaboué A, et al. Reply to P. Gazzaniga et al. JCO Precis Oncol. 2021;5:391-392doi: 10.1200/PO.20.00465.
Bouchahda, M., Saffroy, R., Karaboué, A., Hamelin, J., Innominato, P., Saliba, F., Bosselut, N., Lemoine, A., & Lévi, F. (2021). Reply to P. Gazzaniga et al. JCO precision oncology, 5391-392. https://doi.org/10.1200/PO.20.00465
Bouchahda, Mohamed, et al. "Reply to P. Gazzaniga et al." JCO precision oncology vol. 5 (2021): 391-392. doi: https://doi.org/10.1200/PO.20.00465
Bouchahda M, Saffroy R, Karaboué A, Hamelin J, Innominato P, Saliba F, Bosselut N, Lemoine A, Lévi F. Reply to P. Gazzaniga et al. JCO Precis Oncol. 2021 Nov;5:391-392. doi: 10.1200/PO.20.00465. PMID: 34994602.
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Generation of HLA Allele-Specific Spectral Libraries to Identify and Quantify Immunopeptidomes by SWATH/DIA-MS.

Methods in molecular biology (Clifton, N.J.)

Kovalchik K, Hamelin D, Caron E.
PMID: 34905171
Methods Mol Biol. 2022;2420:137-147. doi: 10.1007/978-1-0716-1936-0_11.

Developing a deep and comprehensive understanding of the collection of peptides presented by class I human leukocyte antigens (HLA ), collectively referred to as the immunopeptidome , is conducive to the success of a wide range of immunotherapies. The...

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Kovalchik K, Hamelin D, Caron E. Generation of HLA Allele-Specific Spectral Libraries to Identify and Quantify Immunopeptidomes by SWATH/DIA-MS. Methods Mol Biol. 2022;2420:137-147doi: 10.1007/978-1-0716-1936-0_11.
Kovalchik, K., Hamelin, D., & Caron, E. (2022). Generation of HLA Allele-Specific Spectral Libraries to Identify and Quantify Immunopeptidomes by SWATH/DIA-MS. Methods in molecular biology (Clifton, N.J.), 2420137-147. https://doi.org/10.1007/978-1-0716-1936-0_11
Kovalchik, Kevin, et al. "Generation of HLA Allele-Specific Spectral Libraries to Identify and Quantify Immunopeptidomes by SWATH/DIA-MS." Methods in molecular biology (Clifton, N.J.) vol. 2420 (2022): 137-147. doi: https://doi.org/10.1007/978-1-0716-1936-0_11
Kovalchik K, Hamelin D, Caron E. Generation of HLA Allele-Specific Spectral Libraries to Identify and Quantify Immunopeptidomes by SWATH/DIA-MS. Methods Mol Biol. 2022;2420:137-147. doi: 10.1007/978-1-0716-1936-0_11. PMID: 34905171.
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Reply to P. Gazzaniga et al.

JCO precision oncology

Bouchahda M, Saffroy R, Karaboué A, Hamelin J, Innominato P, Saliba F, Bosselut N, Lemoine A, Lévi F.
PMID: 34994602
JCO Precis Oncol. 2021 Nov;5:391-392. doi: 10.1200/PO.20.00465.

No abstract available.

Cite
Bouchahda M, Saffroy R, Karaboué A, et al. Reply to P. Gazzaniga et al. JCO Precis Oncol. 2021;5:391-392doi: 10.1200/PO.20.00465.
Bouchahda, M., Saffroy, R., Karaboué, A., Hamelin, J., Innominato, P., Saliba, F., Bosselut, N., Lemoine, A., & Lévi, F. (2021). Reply to P. Gazzaniga et al. JCO precision oncology, 5391-392. https://doi.org/10.1200/PO.20.00465
Bouchahda, Mohamed, et al. "Reply to P. Gazzaniga et al." JCO precision oncology vol. 5 (2021): 391-392. doi: https://doi.org/10.1200/PO.20.00465
Bouchahda M, Saffroy R, Karaboué A, Hamelin J, Innominato P, Saliba F, Bosselut N, Lemoine A, Lévi F. Reply to P. Gazzaniga et al. JCO Precis Oncol. 2021 Nov;5:391-392. doi: 10.1200/PO.20.00465. PMID: 34994602.
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Optimized precursor to simplify assignment transfer between backbone resonances and stereospecifically labelled valine and leucine methyl groups: application to human Hsp90 N-terminal domain.

Journal of biomolecular NMR

Henot F, Kerfah R, Törner R, Macek P, Crublet E, Gans P, Frech M, Hamelin O, Boisbouvier J.
PMID: 34041691
J Biomol NMR. 2021 Jul;75(6):221-232. doi: 10.1007/s10858-021-00370-0. Epub 2021 May 27.

Methyl moieties are highly valuable probes for quantitative NMR studies of large proteins. Hence, their assignment is of the utmost interest to obtain information on both interactions and dynamics of proteins in solution. Here, we present the synthesis of...

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Henot F, Kerfah R, Törner R, et al. Optimized precursor to simplify assignment transfer between backbone resonances and stereospecifically labelled valine and leucine methyl groups: application to human Hsp90 N-terminal domain. J Biomol NMR. 2021;75(6):221-232doi: 10.1007/s10858-021-00370-0.
Henot, F., Kerfah, R., Törner, R., Macek, P., Crublet, E., Gans, P., Frech, M., Hamelin, O., & Boisbouvier, J. (2021). Optimized precursor to simplify assignment transfer between backbone resonances and stereospecifically labelled valine and leucine methyl groups: application to human Hsp90 N-terminal domain. Journal of biomolecular NMR, 75(6), 221-232. https://doi.org/10.1007/s10858-021-00370-0
Henot, Faustine, et al. "Optimized precursor to simplify assignment transfer between backbone resonances and stereospecifically labelled valine and leucine methyl groups: application to human Hsp90 N-terminal domain." Journal of biomolecular NMR vol. 75,6 (2021): 221-232. doi: https://doi.org/10.1007/s10858-021-00370-0
Henot F, Kerfah R, Törner R, Macek P, Crublet E, Gans P, Frech M, Hamelin O, Boisbouvier J. Optimized precursor to simplify assignment transfer between backbone resonances and stereospecifically labelled valine and leucine methyl groups: application to human Hsp90 N-terminal domain. J Biomol NMR. 2021 Jul;75(6):221-232. doi: 10.1007/s10858-021-00370-0. Epub 2021 May 27. PMID: 34041691.
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In Vitro and In Vivo Characterization of MCT1 Inhibitor AZD3965 Confirms Preclinical Safety Compatible with Breast Cancer Treatment.

Cancers

Benyahia Z, Blackman MCNM, Hamelin L, Zampieri LX, Capeloa T, Bedin ML, Vazeille T, Schakman O, Sonveaux P.
PMID: 33540599
Cancers (Basel). 2021 Feb 02;13(3). doi: 10.3390/cancers13030569.

To survive and proliferate in solid tumors, cancer cells adapt and evolve rapidly in microenvironments where oxygen and substrate bioavailability fluctuates over time and space. This creates metabolic heterogeneity. Cancer cells can further cooperate metabolically, for example by swapping...

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Benyahia Z, Blackman MCNM, Hamelin L, et al. In Vitro and In Vivo Characterization of MCT1 Inhibitor AZD3965 Confirms Preclinical Safety Compatible with Breast Cancer Treatment. Cancers (Basel). 2021;13(3)doi: 10.3390/cancers13030569.
Benyahia, Z., Blackman, M. C. N. M., Hamelin, L., Zampieri, L. X., Capeloa, T., Bedin, M. L., Vazeille, T., Schakman, O., & Sonveaux, P. (2021). In Vitro and In Vivo Characterization of MCT1 Inhibitor AZD3965 Confirms Preclinical Safety Compatible with Breast Cancer Treatment. Cancers, 13(3), . https://doi.org/10.3390/cancers13030569
Benyahia, Zohra, et al. "In Vitro and In Vivo Characterization of MCT1 Inhibitor AZD3965 Confirms Preclinical Safety Compatible with Breast Cancer Treatment." Cancers vol. 13,3 (2021). doi: https://doi.org/10.3390/cancers13030569
Benyahia Z, Blackman MCNM, Hamelin L, Zampieri LX, Capeloa T, Bedin ML, Vazeille T, Schakman O, Sonveaux P. In Vitro and In Vivo Characterization of MCT1 Inhibitor AZD3965 Confirms Preclinical Safety Compatible with Breast Cancer Treatment. Cancers (Basel). 2021 Feb 02;13(3). doi: 10.3390/cancers13030569. PMID: 33540599; PMCID: PMC7867268.
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The importance of evaluating differences in HES formulations used in hematopoietic progenitor cell cryopreservation.

Cytotherapy

Halpenny M, William N, Elmoazzen H, Giulivi A, Martin L, Perron D, Bredeson C, Hamelin L, Huebsch L, Yang L, Birch P, Acker JP.
PMID: 34688545
Cytotherapy. 2021 Oct 20; doi: 10.1016/j.jcyt.2021.09.006. Epub 2021 Oct 20.

No abstract available.

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Halpenny M, William N, Elmoazzen H, et al. The importance of evaluating differences in HES formulations used in hematopoietic progenitor cell cryopreservation. Cytotherapy. 2021;doi: 10.1016/j.jcyt.2021.09.006.
Halpenny, M., William, N., Elmoazzen, H., Giulivi, A., Martin, L., Perron, D., Bredeson, C., Hamelin, L., Huebsch, L., Yang, L., Birch, P., & Acker, J. P. (2021). The importance of evaluating differences in HES formulations used in hematopoietic progenitor cell cryopreservation. Cytotherapy, . https://doi.org/10.1016/j.jcyt.2021.09.006
Halpenny, Michael, et al. "The importance of evaluating differences in HES formulations used in hematopoietic progenitor cell cryopreservation." Cytotherapy vol. (2021). doi: https://doi.org/10.1016/j.jcyt.2021.09.006
Halpenny M, William N, Elmoazzen H, Giulivi A, Martin L, Perron D, Bredeson C, Hamelin L, Huebsch L, Yang L, Birch P, Acker JP. The importance of evaluating differences in HES formulations used in hematopoietic progenitor cell cryopreservation. Cytotherapy. 2021 Oct 20; doi: 10.1016/j.jcyt.2021.09.006. Epub 2021 Oct 20. PMID: 34688545.
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A cluster of tetrodotoxin poisoning in Oman.

Clinical toxicology (Philadelphia, Pa.)

Alhatali B, Al Lawatia S, Khamis F, Kantur S, Al-Abri S, Kapil V, Thomas J, Johnson R, Hamelin EI, Coleman RM, Kazzi Z.
PMID: 33913398
Clin Toxicol (Phila). 2021 Apr 29;1-5. doi: 10.1080/15563650.2021.1917595. Epub 2021 Apr 29.

INTRODUCTION: Tetrodotoxin (TTX) is a potent sodium channel blocker, with significant neurotoxicity, found in marine animals like pufferfish and blue-ringed octopus. The severity of toxicity depends on the amount of toxin ingested and the outcome depends on the time-lapse...

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Alhatali B, Al Lawatia S, Khamis F, et al. A cluster of tetrodotoxin poisoning in Oman. Clin Toxicol (Phila). 2021;1-5doi: 10.1080/15563650.2021.1917595.
Alhatali, B., Al Lawatia, S., Khamis, F., Kantur, S., Al-Abri, S., Kapil, V., Thomas, J., Johnson, R., Hamelin, E. I., Coleman, R. M., & Kazzi, Z. (2021). A cluster of tetrodotoxin poisoning in Oman. Clinical toxicology (Philadelphia, Pa.), 1-5. https://doi.org/10.1080/15563650.2021.1917595
Alhatali, Badria, et al. "A cluster of tetrodotoxin poisoning in Oman." Clinical toxicology (Philadelphia, Pa.) vol. (2021): 1-5. doi: https://doi.org/10.1080/15563650.2021.1917595
Alhatali B, Al Lawatia S, Khamis F, Kantur S, Al-Abri S, Kapil V, Thomas J, Johnson R, Hamelin EI, Coleman RM, Kazzi Z. A cluster of tetrodotoxin poisoning in Oman. Clin Toxicol (Phila). 2021 Apr 29;1-5. doi: 10.1080/15563650.2021.1917595. Epub 2021 Apr 29. PMID: 33913398.
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Showing 25 to 36 of 89 entries