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Showing 457 to 465 of 465 entries
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Spray-Congealing and Wet-Sieving as Alternative Processes for Engineering of Inhalation Carrier Particles: Comparison of Surface Properties, Blending and In Vitro Performance.

Pharmaceutical research

Pinto JT, Zellnitz S, Guidi T, Schiaretti F, Schroettner H, Paudel A.
PMID: 34114162
Pharm Res. 2021 Jun;38(6):1107-1123. doi: 10.1007/s11095-021-03061-5. Epub 2021 Jun 10.

PURPOSE: Traditionally, α-lactose monohydrate is the carrier of choice in dry powder inhaler (DPI) formulations. Nonetheless, other sugars, such as D-mannitol, have emerged as potential alternatives. Herein, we explored different particle engineering processes to produce D-mannitol carriers for inhaled...

Treatment of necrotizing enterocolitis by conditioned medium derived from human amniotic fluid stem cells.

PloS one

O'Connell JS, Li B, Zito A, Ahmed A, Cadete M, Ganji N, Lau E, Alganabi M, Farhat N, Lee C, Eaton S, Mitchell R, Ray S, De Coppi P, Patel K, Pierro A.
PMID: 34855833
PLoS One. 2021 Dec 02;16(12):e0260522. doi: 10.1371/journal.pone.0260522. eCollection 2021.

PURPOSE: Necrotizing enterocolitis (NEC) is one of the most distressing gastrointestinal emergencies affecting neonates. Amniotic fluid stem cells (AFSC) improve intestinal injury and survival in experimental NEC but are difficult to administer. In this study, we evaluated whether conditioned...

Dual effects of atorvastatin on angiogenesis pathways in the differentiation of mesenchymal stem cells.

European journal of pharmacology

Khalighfard S, Khori V, Alizadeh AM, Vahabzadeh G, Tajaldini M, Sedighi S, Nozarian Z, Khodayari H, Khodayari S, Ganji F, Veisi Malekshahi Z, Mirmajidi T.
PMID: 34217710
Eur J Pharmacol. 2021 Sep 15;907:174281. doi: 10.1016/j.ejphar.2021.174281. Epub 2021 Jul 01.

Atorvastatin (ATO) can improve the transplantation efficacy of mesenchymal stem cells (MSCs) after acute myocardial infarction. The present study aimed at ATO effects on the angiogenesis-signaling pathways from MSCs' differentiation to tissue angiogenesis. MSCs were first prepared from BALB/c...

Mitochondrial complex-I abnormalities underlie neurodegeneration and cognitive decline in Alzheimer's disease.

European journal of neurology

Terada T, Therriault J, Kang MS, Savard M, Pascoal TA, Lussier F, Tissot C, Wang YT, Benedet A, Poltronetti NM, Ottoy J, Arias JF, Bezgin G, Matsudaira T, Bunai T, Obi T, Tsukada H, Ouchi Y, Rosa-Neto P.
PMID: 35007366
Eur J Neurol. 2022 Jan 10; doi: 10.1111/ene.15246. Epub 2022 Jan 10.

BACKGROUND: Abnormal mitochondrial metabolism has been described in Alzheimer's disease (AD) brain. However, the relationship between AD pathophysiology and key mitochondrial processes remains elusive. The purpose of this study is to investigate whether mitochondrial complex I dysfunction is associated...

High-frequency near-infrared diode laser irradiation suppresses IL-1β-induced inflammatory cytokine expression and NF-κB signaling pathways in human primary chondrocytes.

Lasers in medical science

Sakata S, Kunimatsu R, Tsuka Y, Nakatani A, Gunji H, Yanoshita M, Kado I, Ito S, Putranti NAR, Prasetya RC, Hirose N, Tanimoto K.
PMID: 34363129
Lasers Med Sci. 2021 Aug 07; doi: 10.1007/s10103-021-03371-5. Epub 2021 Aug 07.

Osteoarthritis (OA) and rheumatoid arthritis (RA) are common inflammation-associated cartilage degenerative diseases. Recent studies have shown that low-level diode laser treatment can reduce inflammatory cytokine expressions in cartilage. We recently reported that high-frequency low-level diode laser irradiation attenuates matrix...

Huge carbuncle leading to necrotizing fasciitis in the COVID-19 pandemic era.

Clinical case reports

Gheisari M, Baghani M, Ganji R, Forouzanfar MM.
PMID: 33768893
Clin Case Rep. 2021 Jan 28;9(3):1583-1586. doi: 10.1002/ccr3.3839. eCollection 2021 Mar.

Although Necrotizing fasciitis can evolve from a trivial lesion, whenever it develops it requires a prompt surgical intervention and broad-spectrum antibiotic therapy.

A Randomized Clinical Trial of Intratracheal Administration of Surfactant and Budesonide Combination in Comparison to Surfactant for Prevention of Bronchopulmonary Dysplasia.

Oman medical journal

Gharehbaghi MM, Ganji S, Mahallei M.
PMID: 34447583
Oman Med J. 2021 Jul 31;36(4):e289. doi: 10.5001/omj.2021.84. eCollection 2021 Jul.

OBJECTIVES: Bronchopulmonary dysplasia (BPD) remains a major problem in preterm infants occurring in up to 50% of infants born at < 28 weeks gestational age. Inflammation plays an important role in the pathogenesis of BPD. This study was conducted...

The Italian Deaf Community at the Time of Coronavirus.

Frontiers in sociology

Tomasuolo E, Gulli T, Volterra V, Fontana S.
PMID: 33869529
Front Sociol. 2021 Jan 14;5:612559. doi: 10.3389/fsoc.2020.612559. eCollection 2020.

The present paper will explore the impacts of the recent pandemic crisis on the Italian Deaf community, as a linguistic minority. Recent research has shown that minorities are suffering much more the effects of the pandemia because their lack...

The Relationship Between Selected Load-Velocity Profile Parameters and 50 m Front Crawl Swimming Performance.

Frontiers in physiology

Gonjo T, Njøs N, Eriksrud O, Olstad BH.
PMID: 33679439
Front Physiol. 2021 Feb 19;12:625411. doi: 10.3389/fphys.2021.625411. eCollection 2021.

The purpose of the present study was to establish relationships between sprint front crawl performance and a swimming load-velocity profile. Fourteen male national-level swimmers performed 50 m front crawl and semi-tethered swimming with three progressive loads. The 50 m...

Showing 457 to 465 of 465 entries